Page last updated: 2024-11-12

resolvin d5

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

resolvin D5: isolated from E coli; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

resolvin D5 : A member of the class of resolvins that is (4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying two hydroxy substituents at positions 7 and 17 (the 7S,17S-stereoisomer). [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID16061139
CHEBI ID138645
SCHEMBL ID12698945
MeSH IDM0574409

Synonyms (12)

Synonym
resolvin d5
(5z,7s,8e,10z,13z,15z,17s,19z)-7,17-dihydroxydocosahexaenoic acid
7s,17s-dihydroxy-5z,8e,10z,13z,15e,19z-docosahexaenoic acid
(5z,7s,8e,10z,13z,15z,17s,19z)-7,17-dihydroxydocosa-5,8,10,13,15,19-hexaenoic acid
CHEBI:138645
SCHEMBL12698945
LMFA04030003
7s,17s-dihydroxy-docosa-5z,8e,10z,13z,15e,19z-hexaenoic acid
7s,17s-dihydroxy-docosa-5z,8e,10z,13z,15e,19z-hexaenoate
rvd5
Q59864199
(5z,7s,8e,10z,13z,15e,17s,19z)-7,17-dihydroxydocosa-5,8,10,13,15,19-hexaenoic acid

Research Excerpts

Overview

Resolvin D5 (RvD5) is a metabolite of docosahexanoic acid with anti-inflammatory activity. It has not yet been thoroughly investigated because of its low biological availability.

ExcerptReferenceRelevance
"Resolvin D5 (RvD5) is a specialized pro-resolving lipid mediator with potent anti-inflammatory and analgesic properties. "( Sex Dimorphism in Resolvin D5-induced Analgesia in Rat Models of Trigeminal Pain.
Araya, EI; Baggio, DF; Chichorro, JG; da Luz, FMR; Ferreira, LEN; Lopes, RV, 2023
)
2.69
"Resolvin D5 (RvD5) is a metabolite of docosahexanoic acid with anti-inflammatory activity that has not yet been thoroughly investigated because of its low biological availability. "( Total Synthesis of Resolvin D5.
Kobayashi, Y; Morita, M; Ogawa, N; Suganuma, Y; Sugiyama, T, 2017
)
2.23
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pathways (6)

PathwayProteinsCompounds
Metabolism14961108
Metabolism of lipids500463
Biosynthesis of specialized proresolving mediators (SPMs)13107
Biosynthesis of DHA-derived SPMs1156
Biosynthesis of D-series resolvins415
Docosahexaenoic acid oxylipin metabolism036

Research

Studies (20)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (45.00)24.3611
2020's11 (55.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.22

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.22 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.71 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.22)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (4.76%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational1 (4.76%)0.25%
Other19 (90.48%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]