isoflurane has been researched along with Depression in 5 studies
Isoflurane: A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We employed the CUMS model of depression to assess the rapid antidepressant effect of isoflurane by the forced swimming test (FST), the sucrose preference test (SPT), and the novelty suppressed feeding test (NSFT)." | 3.91 | Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice. ( Jin, JY; Jin, SJ; Si, XM; Tian, YH; Wang, WC; Xu, H; Zhang, L; Zhang, SS; Zhao, JX, 2019) |
| "Depression is a profound mental disorder that dampens the mood and undermines volition, which exhibited an increased incidence over the years." | 3.01 | A synopsis of multitarget therapeutic effects of anesthetics on depression. ( Wu, G; Xu, H, 2023) |
| "Isoflurane was previously the major clinical anesthetic agent but is now mainly used for veterinary anesthesia." | 1.42 | Postanesthetic effects of isoflurane on behavioral phenotypes of adult male C57BL/6J mice. ( Asakura, A; Goto, T; Kobayashi, A; Miyazaki, T; Takase, K; Uchimoto, K; Yonezaki, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, G | 1 |
| Xu, H | 2 |
| Herbst, LS | 1 |
| Gaigher, T | 1 |
| Siqueira, AA | 1 |
| Joca, SRL | 1 |
| Sampaio, KN | 1 |
| Beijamini, V | 1 |
| Zhang, SS | 1 |
| Tian, YH | 1 |
| Jin, SJ | 1 |
| Wang, WC | 1 |
| Zhao, JX | 1 |
| Si, XM | 1 |
| Zhang, L | 1 |
| Jin, JY | 1 |
| Yonezaki, K | 1 |
| Uchimoto, K | 1 |
| Miyazaki, T | 1 |
| Asakura, A | 1 |
| Kobayashi, A | 1 |
| Takase, K | 1 |
| Goto, T | 1 |
| Sackey, PV | 1 |
| Martling, CR | 1 |
| Carlswärd, C | 1 |
| Sundin, O | 1 |
| Radell, PJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Mirus™ for Sedation in Resuscitation[NCT02889055] | 9 participants (Actual) | Observational | 2016-01-17 | Terminated (stopped due to Safety profile was not satisfying with sevolflurane) | |||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05327296] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-06-30 | Recruiting | ||
| A Phase 3, Multicenter, Randomized, Controlled, Open Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensi[NCT05312385] | Phase 3 | 235 participants (Anticipated) | Interventional | 2022-04-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for isoflurane and Depression
| Article | Year |
|---|---|
A synopsis of multitarget therapeutic effects of anesthetics on depression.
Topics: Anesthetics; Depression; Humans; Isoflurane; Ketamine; Propofol; Receptors, AMPA; Receptors, N-Methy | 2023 |
1 trial available for isoflurane and Depression
| Article | Year |
|---|---|
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
Short- and long-term follow-up of intensive care unit patients after sedation with isoflurane and midazolam--a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Conscious Sedation; Delusions; Depress | 2008 |
3 other studies available for isoflurane and Depression
| Article | Year |
|---|---|
New evidence for refinement of anesthetic choice in procedures preceding the forced swimming test and the elevated plus-maze.
Topics: Anesthetics, General; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal | 2019 |
Isoflurane produces antidepressant effects inducing BDNF-TrkB signaling in CUMS mice.
Topics: Anesthetics, Inhalation; Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Depressi | 2019 |
Postanesthetic effects of isoflurane on behavioral phenotypes of adult male C57BL/6J mice.
Topics: Anesthetics, Inhalation; Animals; Anxiety; Attention; Behavior, Animal; Depression; Isoflurane; Male | 2015 |