| Assay ID | Title | Year | Journal | Article |
|---|
| AID526332 | Analgesic activity in subcutaneously dosed mouse assessed as inhibition of acetic-acid-induced writhings | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. |
| AID1877607 | Increase in number of nociceptive behaviors in mouse at 3 to 30 ug, it | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID689650 | Selectivity ratio of Ki for mu opioid receptor in mouse whole brain without cerebellum to Ki for delta opioid receptor in mouse whole brain without cerebellum | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19
| Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands. |
| AID1461556 | Antimicrobial activity against Trichomonas vaginalis after 48 hrs by neutral red staining based invert microscopic analysis | 2017 | Bioorganic & medicinal chemistry, 08-15, Volume: 25, Issue:16
| Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives. |
| AID526328 | Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membranes | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. |
| AID1877609 | Increase in number of nociceptive behaviors in mouse at 30 ug, it | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID1877604 | Agonist activity at MRGPRX2 (unknown origin) expressed in HEK293 cells assessed as induction of G(o) dissociation by measuring luminescent decay at 32 uM by NanoBiT-G-protein dissociation assay | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID526329 | Selectivity ratio, ratio of Ki for mouse brain mu opioid receptor to Ki for mouse brain delta opioid receptor | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. |
| AID689648 | Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19
| Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands. |
| AID526327 | Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain membranes | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. |
| AID1877610 | Increase in number of scratching behaviors in mouse at 3 to 300 ug, id | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID526326 | Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain membranes | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. |
| AID689651 | Selectivity ratio of Ki for kappa opioid receptor in guinea pig cerebellum to Ki for delta opioid receptor in mouse whole brain without cerebellum | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19
| Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands. |
| AID1668244 | Antidepressant activity in mouse at 10 mg/kg, sc by forced swim tes | 2020 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 30, Issue:12
| Discovery of δ opioid receptor full agonists lacking a basic nitrogen atom and their antidepressant-like effects. |
| AID1668241 | Antidepressant activity in sc dosed mouse assessed as increase in total swimming count by forced swim test | 2020 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 30, Issue:12
| Discovery of δ opioid receptor full agonists lacking a basic nitrogen atom and their antidepressant-like effects. |
| AID526330 | Selectivity ratio, ratio of Ki for mouse brain mu opioid receptor to Ki for guinea pig cerebellum kappa opioid receptor | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. |
| AID1668240 | Antidepressant activity in sc dosed mouse assessed as decrease in total immobility count by forced swim test | 2020 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 30, Issue:12
| Discovery of δ opioid receptor full agonists lacking a basic nitrogen atom and their antidepressant-like effects. |
| AID1877606 | Agonist activity at mouse Mrgprb2 expressed in HEK293 cells assessed as induction of G(o) dissociation by measuring luminescent decay at 32 uM by NanoBiT-G-protein dissociation assay | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID689647 | Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19
| Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands. |
| AID1877611 | Increase in number of scratching behaviors in mouse at 400 ug, id trated after dosing of subcutaneous dosing of antipruritic-nalfurafin | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID1877602 | Binding affinity to opioid receptor (unknown origin) | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID1668242 | Antidepressant activity in sc dosed mouse assessed as increase in climbing count by forced swim test | 2020 | Bioorganic & medicinal chemistry letters, 06-15, Volume: 30, Issue:12
| Discovery of δ opioid receptor full agonists lacking a basic nitrogen atom and their antidepressant-like effects. |
| AID1877608 | Increase in number of nociceptive behaviors in mouse at 30 ug, it treated 5 mins after intrathecal dose of MRGPRX2/Mrgprb2 antagonist QWF | 2022 | Bioorganic & medicinal chemistry letters, 01-15, Volume: 56 | Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands. |
| AID689649 | Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum | 2012 | Bioorganic & medicinal chemistry, Oct-01, Volume: 20, Issue:19
| Synthesis of quinolinomorphinan derivatives as highly selective δ opioid receptor ligands. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |