Page last updated: 2024-10-21

homovanillic acid and Depression

homovanillic acid has been researched along with Depression in 136 studies

Homovanillic Acid: A 3-O-methyl ETHER of (3,4-dihydroxyphenyl)acetic acid.
homovanillate : A hydroxy monocarboxylic acid anion which is obtained by deprotonation of the carboxy group of homovanillic acid.
homovanillic acid : A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.

Depression: Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders.

Research Excerpts

ExcerptRelevanceReference
"In the preset study, the authors investigated that effects of the antipsychotic drug risperidone on psychotic depression and examined the mechanism of risperidone to ameliorate psychotic depression."9.12Risperidone in the treatment of psychotic depression. ( Goto, M; Kaji, K; Kakihara, S; Nakamura, J; Shinkai, K; Ueda, N; Yamada, Y; Yoshimura, R, 2006)
"In 46 inpatients with severe DSM III depression, blood counts, serum and red cell folate, serum vitamin B12, total plasma homocysteine, and, in 28 patients, CSF folate, S-adenosylmethionine, and the monoamine neurotransmitter metabolites 5HIAA, HVA, and MHPG were examined."9.09Homocysteine, folate, methylation, and monoamine metabolism in depression. ( Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK, 2000)
" In the present study, clinical characteristics, plasma level of homovanillic acid (pHVA) and two scales - the Eating Attitudes Test (EAT) and the Beck Depression Inventory (BDI) - were assessed in 36 adolescent bulimia nervosa patients (mean age16."7.75Plasma homovanillic acid in adolescents with bulimia nervosa. ( Baeza, I; Bernardo, M; Castro-Fornieles, J; Deulofeu, R; Fernández, L; Lázaro, L; Martínez-Mallen, E; Toro, J; Vila, M, 2009)
"Dopaminergic abnormalities have been described in anorexia nervosa but studies about plasma level of homovanillic acid (pHVA) have yielded conflicting results probably due to the small number and the heterogeneity of patients."7.74Psychopathological and nutritional correlates of plasma homovanillic acid in adolescents with anorexia nervosa. ( Baeza, I; Bernardo, M; Castro-Fornieles, J; Casulà, V; Deulofeu, R; Lázaro, L; Puig, J; Saura, B; Toro, J, 2008)
"In this study we investigated the cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in Alzheimer (AD) patients (n=75), patients with mild cognitive impairment (MCI, n=9) and patients with depression (n=7)."7.725-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. ( Ganzer, S; Müller-Thomsen, T; Stuerenburg, HJ, 2004)
" We measured severity of depression with Beck's Depression Inventory (BDI) and Hamilton's Depression Rating Scale (HDRS), plasma concentrations of cortisol, DHEA and DHEA-S, and CSF concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG) and the dopamine metabolite homovanillic acid (HVA) in 21 abstinent alcoholics after 4 weeks of abstinence and in 11 age-matched healthy control subjects."7.70Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations. ( George, D; Heinz, A; Hommer, D; Linnoila, M; Weingartner, H; Wolkowitz, OM, 1999)
"Treatment of endogenous depression with nortriptyline (NT), at a daily dose of 150 mg, resulted in a pronounced improvement of seven of ten patients investigated."7.67Serotonin uptake inhibition during treatment of depression with nortriptyline caused by parent drug and not by 10-hydroxymetabolites. ( Aberg-Wistedt, A; Bertilsson, L; Malmgren, R, 1987)
"In the preset study, the authors investigated that effects of the antipsychotic drug risperidone on psychotic depression and examined the mechanism of risperidone to ameliorate psychotic depression."5.12Risperidone in the treatment of psychotic depression. ( Goto, M; Kaji, K; Kakihara, S; Nakamura, J; Shinkai, K; Ueda, N; Yamada, Y; Yoshimura, R, 2006)
"In 46 inpatients with severe DSM III depression, blood counts, serum and red cell folate, serum vitamin B12, total plasma homocysteine, and, in 28 patients, CSF folate, S-adenosylmethionine, and the monoamine neurotransmitter metabolites 5HIAA, HVA, and MHPG were examined."5.09Homocysteine, folate, methylation, and monoamine metabolism in depression. ( Bottiglieri, T; Carney, MW; Crellin, R; Laundy, M; Reynolds, EH; Toone, BK, 2000)
"In a double-blind study of 24 patients with endogenous depressiona group treated with clomipramine hydrochloride (chlorimipramine) plus tryptophan was compared with a group treated with clomipramine plus placebo."5.04Potentiation of the antidepressant action of clomipramine by tryptophan. ( Bjorn-Erik, R; Carlsson, A; Nagy, A; Skott, A; Walinder, J, 1976)
"Our hypothesis is that varenicline decreases the plasma levels of catecholamine metabolites; such a decrease is associated with the main mechanisms of smoking cessation and leads to a depressive state."3.78Plasma levels of metabolites of catecholamine in nicotine-dependent patients treated with varenicline. ( Hayashi, K; Hori, H; Ikenouchi-Sugita, A; Katsuki, A; Nakamura, J; Umene-Nakano, W; Yoshii, C; Yoshimura, R, 2012)
" In the present study, clinical characteristics, plasma level of homovanillic acid (pHVA) and two scales - the Eating Attitudes Test (EAT) and the Beck Depression Inventory (BDI) - were assessed in 36 adolescent bulimia nervosa patients (mean age16."3.75Plasma homovanillic acid in adolescents with bulimia nervosa. ( Baeza, I; Bernardo, M; Castro-Fornieles, J; Deulofeu, R; Fernández, L; Lázaro, L; Martínez-Mallen, E; Toro, J; Vila, M, 2009)
"Dopaminergic abnormalities have been described in anorexia nervosa but studies about plasma level of homovanillic acid (pHVA) have yielded conflicting results probably due to the small number and the heterogeneity of patients."3.74Psychopathological and nutritional correlates of plasma homovanillic acid in adolescents with anorexia nervosa. ( Baeza, I; Bernardo, M; Castro-Fornieles, J; Casulà, V; Deulofeu, R; Lázaro, L; Puig, J; Saura, B; Toro, J, 2008)
"In this study we investigated the cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) in Alzheimer (AD) patients (n=75), patients with mild cognitive impairment (MCI, n=9) and patients with depression (n=7)."3.725-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. ( Ganzer, S; Müller-Thomsen, T; Stuerenburg, HJ, 2004)
" We measured severity of depression with Beck's Depression Inventory (BDI) and Hamilton's Depression Rating Scale (HDRS), plasma concentrations of cortisol, DHEA and DHEA-S, and CSF concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), the norepinephrine metabolite 3-methoxy-4-hydroxyphenylglycol (MHPG) and the dopamine metabolite homovanillic acid (HVA) in 21 abstinent alcoholics after 4 weeks of abstinence and in 11 age-matched healthy control subjects."3.70Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations. ( George, D; Heinz, A; Hommer, D; Linnoila, M; Weingartner, H; Wolkowitz, OM, 1999)
"We have measured the concentrations of dopamine, and the dopamine metabolites homovanillic acid (HVA) and dihydroxyphenylacetic acid (DOPAC), in five brain regions from suicide victims with a firm retrospective diagnosis of depression, and matched controls."3.69Reduced dopamine turnover in the basal ganglia of depressed suicides. ( Bowden, C; Cheetham, SC; Crompton, MR; Horton, RW; Katona, CL; Lowther, S, 1997)
"We have investigated the possible associations between the demographic, clinical and psychological characteristics of 80 patients with low back pain and the CSF levels of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and 3-methoxy-4-hydroxyphenylglycol (MHPG), the principal central nervous system metabolites of serotonin, dopamine and noradrenaline, and of tryptophan, the amino acid precursor of serotonin."3.67Neurotransmission and the experience of low back pain; no association between CSF monoamine metabolites and pain. ( Alaranta, H; Hurme, M; Hyyppä, MT; Lahtela, K; Scheinin, H; Scheinin, M, 1985)
"Treatment of endogenous depression with nortriptyline (NT), at a daily dose of 150 mg, resulted in a pronounced improvement of seven of ten patients investigated."3.67Serotonin uptake inhibition during treatment of depression with nortriptyline caused by parent drug and not by 10-hydroxymetabolites. ( Aberg-Wistedt, A; Bertilsson, L; Malmgren, R, 1987)
"5-Hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) were measured in the lumbar cerebrospinal fluid of 57 drug-free female patients with DSM-III diagnoses of major unipolar or bipolar depression (n = 14), schizophrenic disorder (n = 18), alcohol dependence (n = 13) and a group of other disorders (n = 12)."3.66Amine metabolites and neuroendocrine responses related to depression and suicide. ( Arató, M; Banki, CM, 1983)
"The authors report cerebrospinal fluid (CSF) concentrations of five monoamine metabolites before and after probenecid administration in normal subjects and patients with depression and schizophrenia."3.66CSF monoamine metabolites in depression and schizophrenia. ( Anderson, PJ; Barchas, JD; Berger, PA; Davis, KL; Faull, KF; Kilkowski, J; Kraemer, H, 1980)
"The probenecid technique was used in study of the central dopamine DA metabolism in patients with depressions, psychotic disorders, and Parkinson's disease."3.65Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders. ( Korf, J; Praag, HM; Schut, T, 1975)
" The ratio of blood tyrosine and tryptophan is disturbed during depression and recovers during remission."3.65Biochemical post-mortem findings in depressed patients. ( Birkmayer, W; Riederer, P, 1975)
"Depression is one of the leading causes of disability in developing countries including Pakistan."1.46Depressive symptoms, monoamines levels, MAO-B activity and effect of treatment in a subset of depressed individuals from government sector hospital at Karachi. ( Farooq, AD; Naqvi, S; Rahman, R; Zeb, F, 2017)
"Depression and aggression in Alzheimer's disease (AD) are 2 of the most severe and prominent neuropsychiatric symptoms (NPS)."1.40Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease. ( Aerts, T; De Deyn, PP; Engelborghs, S; Van Dam, D; Vermeiren, Y, 2014)
" Taken together, our data indicate that chronic use of stanozolol significantly affects brain monoamines leading to neurochemical modifications possibly involved in depression and stress-related states."1.38Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes. ( Colaianna, M; Cuomo, V; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P; Zotti, M, 2012)
" In 46 children from this sample it was dosed plasmatic cortisol and the urinary excretion of catecholamine, VMA, HVA and 5-HIAA."1.28Biochemical correlate of depression in children. ( Basques, JC; Fabre, ZL; Fernandes, ML; Furtado, CR; Lippi, JR; Lombardi, AB; Peixoto, CC; Queiroz, EA; Soares, TA, 1991)
"Patients with Parkinson's disease have a decrement in homovanillic acid that is reversed by treatment with L-3,4-dihydroxyphenylalanine."1.27Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method. ( Aguado, EG; de Yebenes, JG; Mena, MA, 1984)
"Depression is a common symptom in patients with Parkinson's disease."1.27Altered serotonin metabolism in depressed patients with parkinson's disease. ( Cote, L; Mayeux, R; Stern, Y; Williams, JB, 1984)
"50 pmol/ml) did not change after 1 wk of Li dosing (1."1.27Differences in lithium effects in depressed and healthy subjects. ( Karoum, F; Linnoila, M; Potter, WZ; Ross, RJ; Rudorfer, MV, 1985)
"Depression was by far the most important factor."1.26Cortisol in the CSF of depressed and suicidal patients. ( Asberg, M; Bertilsson, L; Lantto, O; Schalling, D; Träskman, L; Tybring, G, 1980)
"Nortriptyline is a preferential noradrenaline uptake inhibitor, while the dimethylated compound, chlorimipramine also has a profound influence on serotonin neurons."1.26Treatment of depression with tricyclic drugs--pharmacokinetic and pharmacodynamic aspects. ( Asberg, M, 1976)
"Lethargy and mental depression are early symptoms, followed by mild parkinsonism and progressive weight loss."1.26Familial fatal Parkinsonism with alveolar hypoventilation and mental depression. ( Ahmad, D; Barnett, HJ; Bratty, P; Hahn, A; Lloyd, KG; McGeer, EG; Perry, TL; Purdy, A, 1979)
"Two cases of depression are presented: One which responded to psychotherapy and the other which responded to medication."1.26Repertory grid and biochemical characterization of depression: a comparison of case reports. ( Berger, PA; Slater, P; Yesavage, JA, 1979)

Research

Studies (136)

TimeframeStudies, this research(%)All Research%
pre-199086 (63.24)18.7374
1990's10 (7.35)18.2507
2000's20 (14.71)29.6817
2010's15 (11.03)24.3611
2020's5 (3.68)2.80

Authors

AuthorsStudies
Ikenouchi, A1
Okamoto, N1
Igata, R1
Natsuyama, T1
Yoshimura, R4
Tian, P1
Zhang, W1
Li, KY1
Li, HW1
Ma, K1
Han, DE1
Saloner, R1
Cherner, M1
Grelotti, DJ1
Paolillo, EW1
Moore, DJ1
Heaton, RK1
Letendre, SL1
Kumar, A1
Grant, I1
Ellis, RJ1
Chojnacki, C1
Poplawski, T1
Blasiak, J1
Fila, M1
Konrad, P1
Chojnacki, J1
Monchaux De Oliveira, C1
Pourtau, L1
Vancassel, S1
Pouchieu, C1
Capuron, L1
Gaudout, D1
Castanon, N1
Antkiewicz-Michaluk, L1
Romańska, I1
Wąsik, A1
Michaluk, J1
Khnychenko, LK1
Yakovleva, EE1
Bychkov, ER1
Shabanov, PD1
Gaum, PM1
Gube, M1
Schettgen, T1
Putschögl, FM1
Kraus, T1
Fimm, B1
Lang, J1
Zeb, F1
Naqvi, S1
Rahman, R1
Farooq, AD1
Ogawa, S1
Kunugi, H1
Knorr, U1
Forman, J1
Pech, J1
Kessing, LV1
Luykx, JJ1
Bakker, SC1
van Geloven, N1
Eijkemans, MJ1
Horvath, S1
Lentjes, E1
Boks, MP1
Strengman, E1
DeYoung, J1
Buizer-Voskamp, JE1
Cantor, RM1
Lu, A1
van Dongen, EP1
Borgdorff, P1
Bruins, P1
Kahn, RS1
Ophoff, RA1
Kutsuzawa, Y1
Kunii, Y1
Miura, I1
Kanno-Nozaki, K1
Mashiko, H1
Yabe, H1
Niwa, S1
Vermeiren, Y1
Van Dam, D1
Aerts, T1
Engelborghs, S1
De Deyn, PP1
Loseva, EV1
Sarkisova, KY1
Loginova, NA1
Kudrin, VS1
Hama, S1
Murakami, T1
Yamashita, H1
Onoda, K1
Yamawaki, S1
Kurisu, K1
Miller, AH2
Lindqvist, D1
Janelidze, S1
Hagell, P1
Erhardt, S1
Samuelsson, M1
Minthon, L1
Hansson, O1
Björkqvist, M1
Träskman-Bendz, L1
Brundin, L1
Castro-Fornieles, J2
Deulofeu, R2
Martínez-Mallen, E1
Baeza, I2
Fernández, L1
Lázaro, L2
Toro, J2
Vila, M1
Bernardo, M2
Brambilla, F1
Dalle Grave, R1
Calugi, S1
Marchesini, G1
Baroni, S1
Marazziti, D1
Nakano, W1
Nakamura, K1
Shi, X1
Zhang, L1
Fu, S1
Li, N1
Umene-Nakano, W1
Yoshii, C1
Hayashi, K1
Ikenouchi-Sugita, A1
Katsuki, A1
Hori, H1
Nakamura, J2
Tucci, P1
Morgese, MG1
Colaianna, M1
Zotti, M1
Schiavone, S1
Cuomo, V1
Trabace, L1
Miura, H2
Qiao, H2
Ohta, T2
Dalla, C1
Antoniou, K1
Papadopoulou-Daifoti, Z1
Balthazart, J1
Bakker, J1
Carpenter, LL1
Moreno, FA1
Kling, MA1
Anderson, GM1
Regenold, WT1
Labiner, DM1
Price, LH1
Stuerenburg, HJ1
Ganzer, S1
Müller-Thomsen, T1
Mitani, H1
Shirayama, Y1
Yamada, T1
Kawahara, R1
Goto, M1
Kakihara, S1
Shinkai, K1
Yamada, Y1
Kaji, K1
Ueda, N1
Sher, L1
Oquendo, MA1
Grunebaum, MF1
Burke, AK1
Huang, YY1
Mann, JJ1
Casulà, V1
Saura, B1
Puig, J1
Dávila, R1
Zumárraga, M1
Basterreche, N1
Arrúe, A1
Anguiano, JB1
Dhir, A1
Kulkarni, SK1
Felger, JC1
Alagbe, O1
Hu, F1
Mook, D1
Freeman, AA1
Sanchez, MM1
Kalin, NH1
Ratti, E1
Nemeroff, CB1
Mayeux, R2
Träskman, L3
Tybring, G2
Asberg, M5
Bertilsson, L3
Lantto, O1
Schalling, D1
Curzon, G2
Kantamaneni, BD2
Van Boxel, P1
Gillman, PK1
Bartlett, JR2
Bridges, PK2
Anokhina, IP1
Gamaleia, NB1
Oreland, L1
Wiberg, A1
Sjöstrand, L1
Thorén, P2
Krzyzowski, J1
Lewicka-Wysocka, H1
Lukaszewska, B1
Marcjan, K1
Pacyna, M1
Pietruszewska, I1
Roguska, E1
Stencka, K1
Misionzhnik, EIu2
Vertogradova, OP1
Krasnov, VN1
Salenko, BB1
Klok, CJ1
Brouwer, GJ1
van Praag, HM6
Doogan, D1
Hallert, C1
Aström, J1
Sedvall, G1
Banki, CM2
Arató, M1
Stern, Y1
Cote, L1
Williams, JB1
Mena, MA1
Aguado, EG1
de Yebenes, JG1
Berger, PA3
Faull, KF1
Kilkowski, J1
Anderson, PJ1
Kraemer, H2
Davis, KL1
Barchas, JD2
Rossetti, ZL1
Lai, M1
Hmaidan, Y1
Gessa, GL1
Suzuki, E1
Kanba, S1
Koshikawa, H1
Nibuya, M1
Yagi, G1
Asai, M1
Hibbeln, JR1
Umhau, JC1
George, DT1
Salem, N1
Bowden, C1
Cheetham, SC1
Lowther, S1
Katona, CL1
Crompton, MR1
Horton, RW1
Rilke, O1
Safar, C1
Israel, M1
Barth, T1
Felber, W1
Oehler, J1
Sallinen, J1
Haapalinna, A1
MacDonald, E1
Viitamaa, T1
Lähdesmäki, J1
Rybnikova, E1
Pelto-Huikko, M1
Kobilka, BK1
Scheinin, M2
Galinowski, A1
Heinz, A1
Weingartner, H1
George, D1
Hommer, D1
Wolkowitz, OM1
Linnoila, M2
Bottiglieri, T1
Laundy, M1
Crellin, R1
Toone, BK1
Carney, MW1
Reynolds, EH1
Yadid, G1
Overstreet, DH1
Zangen, A1
Ventura, R1
Cabib, S1
Puglisi-Allegra, S1
Pallis, E1
Thermos, K1
Spyraki, C1
Jimerson, DC3
Post, RM12
Skyler, J1
Bunney, WE5
Ringberger, VA1
Sjöqvist, F1
Tuck, JR1
Purdy, A1
Hahn, A1
Barnett, HJ1
Bratty, P1
Ahmad, D1
Lloyd, KG1
McGeer, EG1
Perry, TL1
Sweeney, D1
Nelson, C1
Bowers, M1
Maas, J1
Heninger, G2
Roccatagliata, G1
Albano, C1
Cocito, L1
Maffini, M1
Puca, FM3
Livrea, P3
Genco, S3
Specchio, LM3
Bandiera, L2
DiReda, L1
Gerner, RH3
Carman, JS1
Gillin, JC2
Goodwin, FK12
Bowers, MB6
Moore, D1
Tarsy, D1
Study, RE1
Maas, JW1
Riederer, P3
Tenk, H1
Werner, H1
Bischko, J1
Rett, A1
Krisper, H1
Praag, HM2
Meltzer, HY1
Young, M1
Metz, J1
Fang, VS1
Schyve, PM1
Arora, RC1
Zarcone, VP1
Brodie, KH1
Sack, R2
Van Scheyen, JD1
Korf, J4
Sandler, M1
Ruthven, CR1
Goodwin, BL1
Reynolds, GP1
Rao, VA1
Coppen, A2
Gold, PW1
Wehr, T1
Rebar, R1
Terenius, L1
Wahlström, A1
Agren, H1
Yesavage, JA1
Slater, P1
Heninger, GR1
Vestergaard, P1
Sørensen, T1
Hoppe, E1
Rafaelsen, OJ1
Yates, CM1
Nicolaou, N1
Major, LJ1
Murphy, DL1
Lipper, S1
Gordon, E1
Kirstein, L1
Schilkrut, R1
Rüther, E1
Ackenheil, M1
Eben, E1
Hippius, H1
Walinder, J1
Skott, A1
Carlsson, A1
Nagy, A1
Bjorn-Erik, R1
Sepping, P1
Di Reda, L2
Lamberti, P1
Papagno, G1
Takahashi, S2
Kondo, H2
Kato, N2
Ban, TA1
Jori, A1
Dolfini, E1
Casati, C1
Argenta, G1
Siever, L1
Angwin, P1
Berger, P1
Zarcone, V1
Barchas, J1
Brodie, HK1
Schut, T1
Gordon, EK1
Birkmayer, W2
Gaillard, JM1
Constantinidis, J1
Tissot, R1
Abrams, R1
Essman, WB1
Taylor, MA1
Fink, M1
Kotin, J1
Zubenko, GS1
Moossy, J1
Kopp, U1
Queiroz, EA1
Lombardi, AB1
Furtado, CR1
Peixoto, CC1
Soares, TA1
Fabre, ZL1
Basques, JC1
Fernandes, ML1
Lippi, JR1
Wägner, A1
Malmgren, R1
Aberg-Wistedt, A1
Przuntek, H1
Kuhn, W1
Kraus, P1
Rudorfer, MV1
Karoum, F1
Ross, RJ1
Potter, WZ1
Hyyppä, MT1
Scheinin, H1
Alaranta, H1
Hurme, M1
Lahtela, K1
Metcalfe, M1
Carroll, JD1
Morris, JG1
Ashcroft, GW1
Blackburn, IM1
Eccleston, D1
Glen, AI1
Hartley, W1
Kinloch, NE1
Lonergan, M1
Murray, LG1
Pullar, IA1
Schildkraut, JJ2
Weiss, BL1
Kupfer, DJ1
Foster, FG1
Delgado, J1
Yamane, H1
Tani, N1
Angrist, B1
Sathananthan, G1
Wilk, S1
Gershon, S1
McClure, DJ1
Sack, RL2
Neumayer, E1
Ambrozi, L1
Linauer, W1
Iurkin, MM1
Polishchuk, IuI1
Granerus, AK1
Magnusson, T1
Roos, BE1
Svanborg, A1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Kynurenine Pathway Metabolites in Perinatal Depression and Suicidality[NCT02566980]209 participants (Actual)Observational2014-10-23Completed
Repetitive Transcranial Magnetic Stimulation (rTMS) for Motor and Mood Symptoms of Parkinson's Disease (MASTER-PD), a Multicenter Clinical Trial[NCT01080794]61 participants (Actual)Interventional2010-05-31Completed
Study by 1H NMR of the Variations of the Metabolome During the Course of Electroconvulsive Therapy in Patients With Major Depressive Episode[NCT05973643]50 participants (Anticipated)Interventional2023-10-15Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

The Number All Types of Adverse Events.

To establish the safety and tolerability of rTMS in Parkinson's Disease. (NCT01080794)
Timeframe: Baseline through Month 6

Interventionincidents of an adverse event (Number)
Double rTMS18
M1 Active rTMS + DLPFC Sham rTMS14
DLPFC Active rTMS + M1 Sham rTMS1
Double Sham rTMS1

Apathy Evaluation Scale (AES)

To evaluate apathy in Parkinson's Disease. The AES mean scores were reported for each group at each time point. The AES Score Range is 0-42, where higher the score indicates greater severity of the apathy symptoms. (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post TreatmentMonth 1 Post TreatmentMonth 3 Post TreatmentMonth 6 Post Treatment
DLPFC Active rTMS + M1 Sham rTMS18.718.119.019.315.8
Double rTMS15.616.21716.917.8
Double Sham rTMS16.315.515.016.116.2
M1 Active rTMS + DLPFC Sham rTMS15.916.914.615.112.4

Beck Depression Inventory (BDI-II)

To assess mood symptoms in Parkinson's Disease. The BDI-II mean scores were reported for each group at each time point. The BDI-II Score Range is 0 - 63, where higher the score indicates greater severity of the mood symptoms. (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post TreatmentMonth 1 Post TreatmentMonth 3 Post TreatmentMonth 6 Post Treatment
DLPFC Active rTMS + M1 Sham rTMS21.718.220.219.015.7
Double rTMS23.220.716.417.920.1
Double Sham rTMS18.813.713.114.716.8
M1 Active rTMS + DLPFC Sham rTMS18.516.516.719.116.3

Clinical Anxiety Scale (CAS)

To evaluate anxiety in Parkinson's Disease. The CAS mean scores were reported for each group at each time point. The CAS Score Range is 0 - 100, where higher the score indicates greater severity of the anxiety symptoms. (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post TreatmentMonth 1 Post TreatmentMonth 3 Post TreatmentMonth 6 Post Treatment
DLPFC Active rTMS + M1 Sham rTMS33.427.630.831.424.8
Double rTMS36.334.231.733.133.4
Double Sham rTMS37.532.428.228.535.0
M1 Active rTMS + DLPFC Sham rTMS34.331.030.827.328.1

Global Impression Scales

To assess symptom severity and treatment response in Parkinson's Disease. The CGI mean scores were reported for each group at each time point. The CGI Score Range is 1 - 8, where higher the score indicates greater severity of illness or worsening of illness. (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment): SeverityWeek 1 Post Treatment: SeverityWeek 1 Post Treatment: ImprovementMonth 1 Post Treatment: SeverityMonth 1 Post Treatment: ImprovementMonth 3 Post Treatment: SeverityMonth 3 Post Treatment: ImprovementMonth 6 Post Treatment: SeverityMonth 6 Post Treatment: Improvement
DLPFC Active rTMS + M1 Sham rTMS4.34.73.54.43.74.43.64.33.7
Double rTMS4.94.83.64.43.54.63.74.23.5
Double Sham rTMS3.63.93.04.13.54.43.64.63.4
M1 Active rTMS + DLPFC Sham rTMS4.74.93.54.83.83.83.45.04.2

Hamilton Depression Scale (HAM-D)

"To evaluate the depressive mood symptoms in PD.~The HAM-D mean scores were reported for each group at each time point. The HAM-D Score Range is 0 - 56, where higher the score indicates greater severity of depressive mood symptoms." (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post-TreatmentMonth 1 Post-TreatmentMonth 3 Post-TreatmentMonth 6 Post-Treatment
DLPFC Active rTMS + M1 Sham rTMS13.89.412.410.410.4
Double rTMS15.211.310.610.710.4
Double Sham rTMS14.19.38.011.110.4
M1 Active rTMS + DLPFC Sham rTMS16.711.210.110.18.6

Montreal Cognitive Assessment (MoCA)

To screen and follow cognitive function in Parkinson's Disease. The MoCA mean scores were reported for each group at each time point. The MoCA Score Range is 0 - 30, where 26-30 indicates normal cognition. (NCT01080794)
Timeframe: pre-treatment; 0,1,3, and 6 months post-treatment

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post TreatmentMonth 1 Post TreatmentMonth 3 Post TreatmentMonth 6 Post Treatment
DLPFC Active rTMS + M1 Sham rTMS27.326.326.826.726.6
Double rTMS28.226.828.826.528.0
Double Sham rTMS26.227.828.724.928.0
M1 Active rTMS + DLPFC Sham rTMS26.627.127.225.327.9

Motor Subscale of the Unified Parkinson's Disease Rating Scale (UPDRS Part III)

"To evaluate the motor symptoms in Parkinson's Disease.~The UPDRS-III mean scores were reported for each group at each time point. The UPDRS-III Score Range is 0 - 56, where higher the score indicates greater severity of the motor symptoms." (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post-TreatmentMonth 1 Post-TreatmentMonth 3 Post-TreatmentMonth 6 Post-Treatment
DLPFC Active rTMS + M1 Sham rTMS32.830.329.331.528.8
Double rTMS32.331.230.129.630.5
Double Sham rTMS28.928.228.628.629.0
M1 Active rTMS + DLPFC Sham rTMS33.127.428.133.230.6

Parkinson's Disease Questionnaire 39 (PDQ-39)

To assess the quality of life (QOL) in Parkinson's Disease. The PDQ-39 mean scores were reported for each group at each time point. The PDQ-39 Score Range is 0 - 156, where higher the score indicates greater impact on quality of life. (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post TreatmentMonth 1 Post TreatmentMonth 3 Post TreatmentMonth 6 Post Treatment
DLPFC Active rTMS + M1 Sham rTMS51.946.849.449.449
Double rTMS57.651.249.951.750.5
Double Sham rTMS55.543.140.943.147.5
M1 Active rTMS + DLPFC Sham rTMS61.560.756.853.148.3

Unified Parkinson's Disease Rating Scale (UPDRS) Parts I, II, and IV

"To assess apathy, cognition, depression, activities of daily living (ADL), quality of life (QOL), and motor symptoms in Parkinson's Disease.~The UPDRS I, II, IV total mean scores were reported for each group at each time point. The UPDRS I, II, IV scores were added together for each patient, with a total score range of 0 - 91, where higher the score indicates greater severity of the symptoms." (NCT01080794)
Timeframe: Pre-treatment; Post-treatment 0,1,3, and 6 months.

,,,
Interventionunits on a scale (Mean)
Baseline (Pre-Treatment)Week 1 Post TreatmentMonth 1 Post TreatmentMonth 3 Post TreatmentMonth 6 Post Treatment
DLPFC Active rTMS + M1 Sham rTMS21.519.319.918.920.2
Double rTMS25.423.321.821.123.8
Double Sham rTMS19.615.516.516.918.8
M1 Active rTMS + DLPFC Sham rTMS26.123.223.023.222.7

Reviews

11 reviews available for homovanillic acid and Depression

ArticleYear
Behavioral manifestations of movement disorders. Parkinson's and Huntington's disease.
    Neurologic clinics, 1984, Volume: 2, Issue:3

    Topics: Adult; Aged; Dementia; Depression; Depressive Disorder; Homovanillic Acid; Humans; Huntington Diseas

1984
Do plasma polyunsaturates predict hostility and depression?
    World review of nutrition and dietetics, 1997, Volume: 82

    Topics: Adult; Cholesterol; Depression; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Female; Homovanillic

1997
Studies of amine metabolites in affective illness and in schizophrenia: a comparative analysis.
    Research publications - Association for Research in Nervous and Mental Disease, 1975, Volume: 54

    Topics: 3,4-Dihydroxyphenylacetic Acid; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depressio

1975
Therapy-resistant depressions: biochemical and pharmacological considerations.
    International journal of psychiatry in medicine, 1975, Volume: 6, Issue:1-2

    Topics: Adjustment Disorders; Antidepressive Agents; Brain; Depression; Drug Resistance; Homovanillic Acid;

1975
Pharmacotherapy of depression--a critical review.
    Psychosomatics, 1975, Volume: 16, Issue:1

    Topics: Adjustment Disorders; Antidepressive Agents, Tricyclic; Bipolar Disorder; Brain; Depression; Dopamin

1975
Biochemical effects of antidepressant treatment--studies of monoamine metabolites in cerebrospinal fluid and platelet [3H]imipramine binding.
    Ciba Foundation symposium, 1986, Volume: 123

    Topics: Antidepressive Agents; Blood Platelets; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic A

1986
Simulated behavior states: an approach to specificity in psychobiological research.
    Biological psychiatry, 1973, Volume: 7, Issue:3

    Topics: Biology; Bipolar Disorder; Cyclic AMP; Depression; Emotions; Homovanillic Acid; Humans; Hydroxyindol

1973
Biogenic amines and affective disorders.
    Annual review of medicine, 1974, Volume: 25, Issue:0

    Topics: Affective Symptoms; Biogenic Amines; Bipolar Disorder; Blood Platelets; Brain; Catechol O-Methyltran

1974
The current status of biological criteria for classifying the depressive disorders and predicting responses to treatment.
    Psychopharmacology bulletin, 1974, Volume: 10, Issue:1

    Topics: Adult; Aged; Catechol O-Methyltransferase; Depression; Dextroamphetamine; Dihydroxyphenylalanine; Do

1974
The role of dopamine in depression.
    Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Depression; Dopamine; Homovanillic Acid; Humans; Locomotion; Norepi

1973
Central dopamine function in affective illness: evidence from precursors, enzyme inhibitors, and studies of central dopamine turnover.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: Adult; Affective Symptoms; Anger; Bipolar Disorder; Central Nervous System; Depression; Diagnosis, D

1974

Trials

18 trials available for homovanillic acid and Depression

ArticleYear
Altered dopamine signalling in chronic epigastric pain syndrome.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2020, Volume: 71, Issue:6

    Topics: Abdominal Pain; Adult; Benzamides; Benzyl Compounds; Case-Control Studies; Chronic Pain; Depression;

2020
Effects of cognitive-behavioral therapy on Eating Disorders: neurotransmitter secretory response to treatment.
    Psychoneuroendocrinology, 2010, Volume: 35, Issue:5

    Topics: Adult; Anxiety; Biogenic Monoamines; Body Mass Index; Cognitive Behavioral Therapy; Depression; Feed

2010
Effect of vagus nerve stimulation on cerebrospinal fluid monoamine metabolites, norepinephrine, and gamma-aminobutyric acid concentrations in depressed patients.
    Biological psychiatry, 2004, Sep-15, Volume: 56, Issue:6

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Biogenic Monoamines; Case-Control Studies; Chrom

2004
Risperidone in the treatment of psychotic depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Antipsychotic Agents; Depression; Dose-Res

2006
Fluvoxamine and clomipramine in depressed patients. A double-blind clinical study.
    Acta psychiatrica Scandinavica, 1981, Volume: 64, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Clomipramine; Depression; Diazepam; Do

1981
Homocysteine, folate, methylation, and monoamine metabolism in depression.
    Journal of neurology, neurosurgery, and psychiatry, 2000, Volume: 69, Issue:2

    Topics: Adult; Biogenic Monoamines; Blood Cell Count; Body Weight; Depression; Erythrocytes; Female; Folic A

2000
Effects of a dopamine agonist piribedil in depressed patients: relationship of pretreatment homovanillic acid to antidepressant response.
    Archives of general psychiatry, 1978, Volume: 35, Issue:5

    Topics: Adult; Bipolar Disorder; Clinical Trials as Topic; Depression; Double-Blind Method; Female; Homovani

1978
Tardive dyskinesia: a clinical test of the supersensitivity hypothesis.
    Psychopharmacology, 1979, Mar-22, Volume: 61, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Cyclic AMP; Depression; Dyskinesia, Drug-Induced; Female; Hom

1979
The indoleamine hypothesis of depression: an overview and pilot study.
    Diseases of the nervous system, 1977, Volume: 38, Issue:8

    Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depression; Female; Homovanil

1977
Controlled study comparing nomifensine and clomipramine in unipolar depression, using the probenecid technique.
    British journal of clinical pharmacology, 1977, Volume: 4Suppl 2

    Topics: Adult; Clinical Trials as Topic; Clomipramine; Depression; Dibenzazepines; Double-Blind Method; Fema

1977
Potentiation of the antidepressant action of clomipramine by tryptophan.
    Archives of general psychiatry, 1976, Volume: 33, Issue:11

    Topics: Adolescent; Adult; Aged; Anxiety; Clomipramine; Depression; Dibenzazepines; Drug Synergism; Drug The

1976
Effect of ECT and imipramine treatment on the concentration of 5-hydroxyindoleacetic acid (5HIAA) and homovanillic acid (HVA) in the cerebrospinal fluid of depressed patients.
    Psychopharmacologia, 1975, Oct-14, Volume: 44, Issue:1

    Topics: Adult; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Female; Homovanillic Acid; H

1975
Levodopa and L-tryptophan therapy in Parkinsonism.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Gait; Homovanillic Acid; Humans; Hydroxyindoleacet

1972
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid.
    Psychotherapy and psychosomatics, 1974, Volume: 23, Issue:1-6

    Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans;

1974
Amitriptyline in man: decreased formation of central 5-hydroxyindoleacetic acid.
    Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:2

    Topics: Aged; Amitriptyline; Clinical Trials as Topic; Depression; Female; Homovanillic Acid; Humans; Hydrox

1974
Serotonin metabolism in depression: clinical application of the probenecid test.
    International pharmacopsychiatry, 1974, Volume: 9, Issue:1

    Topics: 5-Hydroxytryptophan; Adjustment Disorders; Administration, Oral; Clinical Trials as Topic; Depressio

1974
Behavioral effects of a new dopamine-beta-hydroxylase inhibitor (fusaric acid) in man.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Administration, Oral; Bipolar Disorder; Clinical Trials as Topic; Depression; Dopamine beta-Hydroxyl

1974
Effects of amitriptyline and imipramine on amine metabolites in the cerebrospinal fluid of depressed patients.
    Archives of general psychiatry, 1974, Volume: 30, Issue:2

    Topics: Adult; Amitriptyline; Biological Transport; Brain Chemistry; Depression; Dopamine; Female; Homovanil

1974

Other Studies

107 other studies available for homovanillic acid and Depression

ArticleYear
The Molecular Mechanism of Exercise for Treatment of Patients with Major Depression: A Preliminary Report on the Dynamics of Metabolites of Nitric Oxide and Catecholamines.
    Journal of integrative neuroscience, 2022, Jun-30, Volume: 21, Issue:4

    Topics: Catecholamines; Depression; Depressive Disorder, Major; Homovanillic Acid; Humans; Methoxyhydroxyphe

2022
[Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:17

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Chromatography, Liquid; Depression;

2022
Lower CSF homovanillic acid relates to higher burden of neuroinflammation and depression in people with HIV disease.
    Brain, behavior, and immunity, 2020, Volume: 90

    Topics: Adult; Biomarkers; Depression; Dopamine; HIV Infections; Homovanillic Acid; Humans

2020
Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission.
    Nutrients, 2021, Mar-11, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Antidepressive Agents; Anxiety; Behav

2021
Antidepressant-Like Effect of the Endogenous Neuroprotective Amine, 1MeTIQ in Clonidine-Induced Depression: Behavioral and Neurochemical Studies in Rats.
    Neurotoxicity research, 2017, Volume: 32, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Biogenic Monoamines; Brain; Brain Che

2017
Effects of Fluorencarbonic Acid Derivative on the Levels of Monoamines and Their Metabolites in Brain Structures of Rats with Modeled Depression-Like State.
    Bulletin of experimental biology and medicine, 2017, Volume: 163, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Chromatography, High Pressure L

2017
Polychlorinated biphenyls and depression: cross-sectional and longitudinal investigation of a dopamine-related Neurochemical path in the German HELPcB surveillance program.
    Environmental health : a global access science source, 2017, 10-10, Volume: 16, Issue:1

    Topics: Adult; Body Burden; Cross-Sectional Studies; Depression; Dopamine; Environmental Exposure; Environme

2017
Depressive symptoms, monoamines levels, MAO-B activity and effect of treatment in a subset of depressed individuals from government sector hospital at Karachi.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:4(Suppl.)

    Topics: Adolescent; Adult; Affect; Aged; Antidepressive Agents, Second-Generation; Biomarkers; Case-Control

2017
Evidence for reduced homovanillic acid (HVA) in the cerebrospinal fluid of patients with depression.
    Journal of affective disorders, 2019, 08-01, Volume: 255

    Topics: Depression; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Neurotransmitt

2019
Low level of evidence for reduced homovanillic acid (HVA) in the cerebrospinal fluid of patients with depression compared to healthy non-psychiatric control individuals.
    Journal of affective disorders, 2019, 10-01, Volume: 257

    Topics: Depression; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Neurotransmitt

2019
Seasonal variation of serotonin turnover in human cerebrospinal fluid, depressive symptoms and the role of the 5-HTTLPR.
    Translational psychiatry, 2013, Oct-08, Volume: 3

    Topics: Adult; Alleles; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Longitudina

2013
High plasma monoamine metabolite levels in Cotard's syndrome.
    Psychiatry and clinical neurosciences, 2014, Volume: 68, Issue:5

    Topics: Catecholamines; Delusions; Depression; Female; Homovanillic Acid; Humans; Methoxyhydroxyphenylglycol

2014
Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:12

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Brain; Chromatography, High Pressure Liquid;

2014
Depressive Behavior and Monoamine Contents in Brain Structures of Rats During Chronic Overcrowding.
    Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Depression; Dopamine; Homovanillic Acid; Hypothalamus; Norepinephr

2015
Neuroanatomic pathways associated with monoaminergic dysregulation after stroke.
    International journal of geriatric psychiatry, 2017, Volume: 32, Issue:6

    Topics: Adult; Affective Symptoms; Aged; Aged, 80 and over; Apathy; Basal Ganglia; Biogenic Monoamines; Depr

2017
Norman Cousins Lecture. Mechanisms of cytokine-induced behavioral changes: psychoneuroimmunology at the translational interface.
    Brain, behavior, and immunity, 2009, Volume: 23, Issue:2

    Topics: Animals; Anxiety; Behavior; Cytokines; Depression; Dopamine; Homovanillic Acid; Humans; Indoleamine-

2009
Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity.
    Biological psychiatry, 2009, Aug-01, Volume: 66, Issue:3

    Topics: Adult; Analysis of Variance; Blood-Brain Barrier; Cytokines; Depression; Female; Homovanillic Acid;

2009
Plasma homovanillic acid in adolescents with bulimia nervosa.
    Psychiatry research, 2009, Dec-30, Volume: 170, Issue:2-3

    Topics: Adolescent; Body Mass Index; Bulimia Nervosa; Chromatography, High Pressure Liquid; Depression; Elec

2009
[Alcoholism and depression: catecholamines and brain-derived neurotrophic factors].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2009, Volume: 111, Issue:7

    Topics: Adult; Aged; Alcoholism; Antidepressive Agents; Biomarkers; Brain-Derived Neurotrophic Factor; Catec

2009
Co-involvement of psychological and neurological abnormalities in infertility with polycystic ovarian syndrome.
    Archives of gynecology and obstetrics, 2011, Volume: 284, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Anxiety; Checklist; Depression; Diagnostic Self Evaluation; Dopamine

2011
Plasma levels of metabolites of catecholamine in nicotine-dependent patients treated with varenicline.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012, Volume: 14, Issue:4

    Topics: Adult; Benzazepines; Catecholamines; Depression; Female; Homovanillic Acid; Humans; Male; Methoxyhyd

2012
Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes.
    Steroids, 2012, Volume: 77, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Depression; Dopamine; Hippocampus; Homovan

2012
Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress.
    Synapse (New York, N.Y.), 2002, Volume: 46, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain; Chromatography, High Pre

2002
Oestrogen-deficient female aromatase knockout (ArKO) mice exhibit depressive-like symptomatology.
    The European journal of neuroscience, 2004, Volume: 20, Issue:1

    Topics: Animals; Anxiety; Aromatase; Behavior, Animal; Biogenic Monoamines; Brain; Brain Chemistry; Depressi

2004
5-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment.
    Neuro endocrinology letters, 2004, Volume: 25, Issue:6

    Topics: Aged; Alzheimer Disease; Cognition Disorders; Depression; Dopamine; Female; Homovanillic Acid; Human

2004
Plasma levels of homovanillic acid, 5-hydroxyindoleacetic acid and cortisol, and serotonin turnover in depressed patients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2006, Volume: 30, Issue:3

    Topics: Adult; Case-Control Studies; Depression; Electrochemistry; Female; Homovanillic Acid; Humans; Hydroc

2006
CSF monoamine metabolites and lethality of suicide attempts in depressed patients with alcohol dependence.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2007, Volume: 17, Issue:1

    Topics: Adult; Alcoholism; Biogenic Monoamines; Depression; Female; Homovanillic Acid; Humans; Hydroxyindole

2007
Psychopathological and nutritional correlates of plasma homovanillic acid in adolescents with anorexia nervosa.
    Journal of psychiatric research, 2008, Volume: 42, Issue:3

    Topics: Adolescent; Anorexia Nervosa; Depression; Female; Follow-Up Studies; Homovanillic Acid; Humans; Male

2008
Plasma homovanillic acid levels in schizophrenic patients: correlation with negative symptoms.
    Psychiatry research, 2007, May-30, Volume: 151, Issue:1-2

    Topics: Adolescent; Adult; Antipsychotic Agents; Depression; Dopamine; Female; Hallucinations; Haloperidol;

2007
Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor.
    European journal of pharmacology, 2007, Jul-30, Volume: 568, Issue:1-3

    Topics: Animals; Antidepressive Agents, Second-Generation; Arginine; Behavior, Animal; Body Temperature; Bra

2007
Effects of interferon-alpha on rhesus monkeys: a nonhuman primate model of cytokine-induced depression.
    Biological psychiatry, 2007, Dec-01, Volume: 62, Issue:11

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Chromatography, High

2007
Cortisol in the CSF of depressed and suicidal patients.
    Archives of general psychiatry, 1980, Volume: 37, Issue:7

    Topics: Adjustment Disorders; Clomipramine; Depression; Female; Homovanillic Acid; Humans; Hydrocortisone; H

1980
Substances related to 5-hydroxytryptamine in plasma and in lumbar and ventricular fluids of psychiatric patients.
    Acta psychiatrica Scandinavica. Supplementum, 1980, Volume: 280

    Topics: Adult; Affective Symptoms; Cerebral Ventricles; Depression; Fatty Acids, Nonesterified; Female; Homo

1980
[Current biochemical conceptions of mental diseases. II. Role of changes in the biogenic amine system in the pathogenesis of affective disorders].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:6

    Topics: 3-Methoxy-4-hydroxyphenylethanol; Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic;

1980
Platelet MAO activity and monoamine metabolites in cerebrospinal fluid in depressed and suicidal patients and in healthy controls.
    Psychiatry research, 1981, Volume: 4, Issue:1

    Topics: Blood Platelets; Depression; Female; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; M

1981
[Metabolism of peripheral catecholamines and indole amines in healthy persons. Clinico-biochemical correlates].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1981, Mar-16, Volume: 36, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Carboxylic Acids; Catecholamines; Depression; Female; Glycols

1981
[Changes in the levels of adrenergic and serotoninergic indices in patients with depressive states].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:4

    Topics: Adolescent; Adult; Biogenic Amines; Depression; Dihydroxyphenylalanine; Dopamine; Epinephrine; Homov

1981
Psychic disturbances in adult coeliac disease. III. Reduced central monoamine metabolism and signs of depression.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:1

    Topics: Adult; Aged; Biogenic Amines; Celiac Disease; Depression; Dopamine; Homovanillic Acid; Humans; Hydro

1982
Amine metabolites and neuroendocrine responses related to depression and suicide.
    Journal of affective disorders, 1983, Volume: 5, Issue:3

    Topics: Alcoholism; Depression; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydro

1983
Altered serotonin metabolism in depressed patients with parkinson's disease.
    Neurology, 1984, Volume: 34, Issue:5

    Topics: Aged; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyp

1984
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression;

1984
CSF monoamine metabolites in depression and schizophrenia.
    The American journal of psychiatry, 1980, Volume: 137, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Mal

1980
Depletion of mesolimbic dopamine during behavioral despair: partial reversal by chronic imipramine.
    European journal of pharmacology, 1993, Oct-05, Volume: 242, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Depression; Disease Models, Animal; Dopami

1993
Negative symptoms in nondeficit syndrome respond to neuroleptic treatment with changes in plasma homovanillic acid concentrations.
    Journal of psychiatry & neuroscience : JPN, 1996, Volume: 21, Issue:3

    Topics: Adult; Aged; Antipsychotic Agents; Depression; Dopamine D2 Receptor Antagonists; Dose-Response Relat

1996
Reduced dopamine turnover in the basal ganglia of depressed suicides.
    Brain research, 1997, Sep-19, Volume: 769, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Aged; Antidepressive Agents; Basal Ganglia; Chrom

1997
Differences in whole blood serotonin levels based on a typology of parasuicide.
    Neuropsychobiology, 1998, Volume: 38, Issue:2

    Topics: Adult; Analysis of Variance; Biomarkers; Case-Control Studies; Depression; Female; Homovanillic Acid

1998
Genetic alteration of the alpha2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels.
    Molecular psychiatry, 1999, Volume: 4, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Cerebral Cortex; Corpus Striatum; Cortico

1999
[The concept of schizoaffective disorder: paraclinical validity of schizoaffective disorder].
    L'Encephale, 1999, Volume: 25 Spec No 4

    Topics: Delirium; Depression; Homovanillic Acid; Humans; Monoamine Oxidase; Psychiatric Status Rating Scales

1999
Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations.
    Psychiatry research, 1999, Dec-20, Volume: 89, Issue:2

    Topics: Adult; Case-Control Studies; Dehydroepiandrosterone; Depression; Ethanol; Female; Homovanillic Acid;

1999
Limbic dopaminergic adaptation to a stressful stimulus in a rat model of depression.
    Brain research, 2001, Mar-30, Volume: 896, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adaptation, Physiological; Animals; Depression; Disease Models, Anim

2001
Opposite genotype-dependent mesocorticolimbic dopamine response to stress.
    Neuroscience, 2001, Volume: 104, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Depression; Disease Models, Animal; Dopam

2001
Chronic desipramine treatment selectively potentiates somatostatin-induced dopamine release in the nucleus accumbens.
    The European journal of neuroscience, 2001, Volume: 14, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents, Tricyclic; Depression; Desipramine;

2001
Attenuating effects of the isolated rearing condition on increased brain serotonin and dopamine turnover elicited by novelty stress.
    Brain research, 2002, Feb-01, Volume: 926, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Depression; Dopamine; Exploratory Behavior; Homovani

2002
Treatment of depression with tricyclic drugs--pharmacokinetic and pharmacodynamic aspects.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:1

    Topics: Antidepressive Agents, Tricyclic; Clomipramine; Depression; Homovanillic Acid; Humans; Hydroxyindole

1976
Prolactin in cerebrospinal fluid and dopamine function in man.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:11

    Topics: Brain; Depression; Dopamine; Homovanillic Acid; Humans; Piribedil; Prolactin

1976
Monoamine metabolites in cerebrospinal fluid and serotonin uptake inhibition during treatment with chlorimipramine.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:2

    Topics: Biogenic Amines; Clomipramine; Depression; Depression, Chemical; Dibenzazepines; Homovanillic Acid;

1977
Familial fatal Parkinsonism with alveolar hypoventilation and mental depression.
    Annals of neurology, 1979, Volume: 6, Issue:6

    Topics: Brain; Brain Chemistry; Depression; Dopa Decarboxylase; Dopamine; gamma-Aminobutyric Acid; Glutamate

1979
Delusional versus non-delusional depression: Neurochemical differences.
    Lancet (London, England), 1978, Jul-08, Volume: 2, Issue:8080

    Topics: Adult; Delusions; Depression; Drug Resistance; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

1978
Interactions between central monoaminergic systems: dopamine-serotonin.
    Journal of neurology, neurosurgery, and psychiatry, 1979, Volume: 42, Issue:12

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Depression; Dopamine; Dyskinesia, Drug-Induced; Female; H

1979
[REM sleep deprivation in normal humans. Changes in anxiety, depression and aggressiveness, and HVA and 5-HIAA levels in the lumbar cerebrospinal fluid].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Jun-15, Volume: 52, Issue:11

    Topics: Adult; Aggression; Anxiety; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; P

1976
Biological and behavioral effects of one night's sleep deprivation in depressed patients and normals.
    Journal of psychiatric research, 1979, Volume: 15, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Body Temperature; Calcium; Circadian Rhythm; Depression; Electroencep

1979
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: studies in psychiatric patients.
    Psychopharmacology, 1979, Mar-29, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Biogenic Amines; Chlorpromazine; Cyclic AMP; Depression; Female; Homovanill

1979
Biochemistry of the affective disorders.
    Hospital practice, 1979, Volume: 14, Issue:5

    Topics: Affective Symptoms; Bipolar Disorder; Body Temperature; Cholinesterase Inhibitors; Circadian Rhythm;

1979
Manipulation of neurotransmitters by acupuncture (?) (A preliminary communication).
    Journal of neural transmission, 1975, Volume: 37, Issue:1

    Topics: Acupuncture Therapy; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Depression; Fema

1975
The Harold E. Himwich Memorial Lecture. Significance of biochemical parameters in the diagnosis, treatment, and prevention of depressive disorders.
    Biological psychiatry, 1977, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Autopsy; Bipolar Disorder; Brain Chemistry; C

1977
Extrapyramidal side effects and increased serum prolactin following fluoxetine, a new antidepressant.
    Journal of neural transmission, 1979, Volume: 45, Issue:2

    Topics: Adult; Antidepressive Agents; Blood Platelets; Depression; Dystonia; Extrapyramidal Tracts; Female;

1979
Deficient production of tyramine and octopamine in cases of depression.
    Nature, 1979, Mar-22, Volume: 278, Issue:5702

    Topics: Aged; Depression; Female; Homovanillic Acid; Humans; Hydroxy Acids; Male; Mandelic Acids; Middle Age

1979
Pituitary thyrotropin response to thyrotropin-releasing hormone in affective illness: relationship to spinal fluid amine metabolites.
    The American journal of psychiatry, 1977, Volume: 134, Issue:9

    Topics: Age Factors; Bipolar Disorder; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Ac

1977
Naloxone (Narcan) treatment in depression: clinical observations and effects on CSF endorphins and monoamine metabolites.
    Psychopharmacology, 1977, Aug-31, Volume: 54, Issue:1

    Topics: Adult; Alcoholism; Biogenic Amines; Depression; Endorphins; Female; Homovanillic Acid; Humans; Hydro

1977
Repertory grid and biochemical characterization of depression: a comparison of case reports.
    The Journal of clinical psychiatry, 1979, Volume: 40, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Depression; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic

1979
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:2

    Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalograp

1977
Biogenic amine metabolites in cerebrospinal fluid of patients with affective disorders.
    Acta psychiatrica Scandinavica, 1978, Volume: 58, Issue:1

    Topics: Adult; Aged; Biogenic Amines; Bipolar Disorder; Depression; Female; Homovanillic Acid; Humans; Hydro

1978
Effects of clorgyline and pargyline on deaminated metabolites of norepinephrine, dopamine and serotonin in human cerebrospinal fluid.
    Journal of neurochemistry, 1979, Volume: 32, Issue:1

    Topics: Clorgyline; Depression; Dopamine; Homovanillic Acid; Humans; Norepinephrine; Pargyline; Propylamines

1979
Cerebrospinal fluid amine metabolites after combined amitriptyline-triiodothyronine treatment of depressed women.
    European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4

    Topics: Adult; Amitriptyline; Biogenic Amines; Depression; Drug Therapy, Combination; Female; Homovanillic A

1977
Nonstriatal dopaminergic neurons: Section XI. Dopaminergic neurons and mental diseases: Introduction: dopaminergic neurons and mental diseases.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Apomorphine; Bromocriptine; Catecholamines; Depression; Dopamine; Homovanillic Acid; Humans; Levodop

1977
CSF amine metabolites, clinical symptoms, and body movement in psychiatric patients.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: Adult; Anger; Anxiety; Arousal; Brain; Depression; Female; Homovanillic Acid; Humans; Hydroxyindolea

1976
A dopaminergic mechanism in mania.
    The American journal of psychiatry, 1976, Volume: 133, Issue:10

    Topics: Bipolar Disorder; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium

1976
Clinical and biochemical parameters during neuroleptic treatment. II. Antipsychotic effect of haloperidol in patients with chronic organic brain damage.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:1

    Topics: Adult; Aged; Brain Damage, Chronic; Depression; Female; Hallucinations; Haloperidol; Homovanillic Ac

1976
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanilli

1976
[Repeated arousal during non-REM sleep in normal humans. Changes in anxiety, depression and aggressiveness and HVA and 5-HIAA levels in the lumbar cerebrospinal fluid].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Jun-15, Volume: 52, Issue:11

    Topics: Adult; Aggression; Anxiety; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; P

1976
[Total sleep deprivation in normal humans. Changes in anxiety, depression and aggressiveness and HVA and 5-HIAA levels in the lumbar cerebrospinal fluid].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Jun-15, Volume: 52, Issue:11

    Topics: Adult; Anxiety; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylacetate

1976
Effect of l-5-hydroxytryptophan on brain monoamine metabolism and evaluation of its clinical effect in depressed patients.
    Journal of psychiatric research, 1975, Volume: 12, Issue:3

    Topics: 5-Hydroxytryptophan; Adjustment Disorders; Adult; Aged; Blood Platelets; Brain; Depression; Female;

1975
Central monoamine deficiency in depressions: causative of secondary phenomenon?
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1975, Volume: 8, Issue:5

    Topics: 5-Hydroxytryptophan; Clomipramine; Depression; Dopamine; Homovanillic Acid; Humans; Serotonin

1975
Gradients of biogenic amine metabolites in cerebrospinal fluid.
    Diseases of the nervous system, 1975, Volume: 36, Issue:1

    Topics: Alzheimer Disease; Amphetamine; Brain Diseases; Brain Neoplasms; Depression; Homovanillic Acid; Huma

1975
Dopamine metabolism in depressions, psychoses, and Parkinson's disease: the problem of the specificity of biological variables in behaviour disorders.
    Psychological medicine, 1975, Volume: 5, Issue:2

    Topics: Adjustment Disorders; Bipolar Disorder; Brain; Carboxy-Lyases; Depression; Dihydroxyphenylalanine; D

1975
Central noradrenergic function in man: vanillylmandelic acid in CSF.
    Brain research, 1975, Dec-05, Volume: 99, Issue:2

    Topics: Acute Disease; Affective Symptoms; Bipolar Disorder; Depression; Homovanillic Acid; Humans; Hydroxyi

1975
Biochemical post-mortem findings in depressed patients.
    Journal of neural transmission, 1975, Volume: 37, Issue:2

    Topics: Aged; Brain Chemistry; Brain Mapping; Circadian Rhythm; Depression; Dopamine; Female; Homovanillic A

1975
Effect of peripheral decarboxylase inhibition on HVA and 5HIAA in cerebrospinal fluid of depressed patients.
    Neuropsychobiology, 1975, Volume: 1, Issue:1

    Topics: Adult; Aged; Benserazide; Depression; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleac

1975
Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies.
    Psychopharmacology communications, 1975, Volume: 1, Issue:6

    Topics: Affective Symptoms; Amines; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipram

1975
Concentration of 5-hydroxyindoleacetic acid, homovanillic acid, and tryptophan in the cerebrospinal fluid of depressed patients before and after ECT.
    Biological psychiatry, 1976, Volume: 11, Issue:1

    Topics: Adult; Brain; Depression; Electroconvulsive Therapy; Homovanillic Acid; Humans; Hydroxyindoleacetic

1976
Effects of sleep deprivation on mood and central amine metabolism in depressed patients.
    Archives of general psychiatry, 1976, Volume: 33, Issue:5

    Topics: Adult; Affect; Aged; Brain; Depression; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleac

1976
Neurochemical correlates of major depression in primary dementia.
    Archives of neurology, 1990, Volume: 47, Issue:2

    Topics: Brain; Choline O-Acetyltransferase; Dementia; Depression; Homovanillic Acid; Humans; Hydroxyindoleac

1990
Biochemical correlate of depression in children.
    Arquivos de neuro-psiquiatria, 1991, Volume: 49, Issue:4

    Topics: Adolescent; Age Factors; Analysis of Variance; Catecholamines; Child; Child, Abandoned; Depression;

1991
Serotonin uptake inhibition during treatment of depression with nortriptyline caused by parent drug and not by 10-hydroxymetabolites.
    Psychopharmacology, 1987, Volume: 92, Issue:2

    Topics: Adult; Blood Platelets; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kin

1987
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPG, HIAA and HVA levels in the cerebrospinal fluid.
    Acta neurologica Scandinavica. Supplementum, 1989, Volume: 126

    Topics: Benserazide; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Glycols; Homovanill

1989
Differences in lithium effects in depressed and healthy subjects.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindol

1985
Neurotransmission and the experience of low back pain; no association between CSF monoamine metabolites and pain.
    Pain, 1985, Volume: 21, Issue:1

    Topics: Adult; Anxiety; Back Pain; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid;

1985
Changes on recovery in the concentrations of tryptophan and the biogenic amine metabolites in the cerebrospinal fluid of patients with affective illness.
    Psychological medicine, 1973, Volume: 3, Issue:3

    Topics: Adult; Affective Symptoms; Antipsychotic Agents; Biogenic Amines; Bipolar Disorder; Butyrophenones;

1973
Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Depression; Fenclo

1974
Psychomotor activity, sleep, and biogenic amine metabolites in depression.
    Biological psychiatry, 1974, Volume: 9, Issue:1

    Topics: Adult; Biological Transport, Active; Circadian Rhythm; Depression; Electroencephalography; Electromy

1974
CSF monoamine metabolites in alcoholism: a comparative study with depression.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:4

    Topics: Adult; Aged; Alcoholism; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Ma

1974
Amphetamine psychosis: behavioral and biochemical aspects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio

1974
Lumbar CSF 5-hydroxyindoleacetic acid and homovanillic acid in affective syndromes.
    The Journal of nervous and mental disease, 1974, Volume: 158, Issue:5

    Topics: Adult; Affective Symptoms; Amitriptyline; Animals; Bipolar Disorder; Brain Chemistry; Cats; Depressi

1974
The daily rhythm of HVA, VMA, (VA) and 5-HIAA in depression-syndrome.
    Journal of neural transmission, 1974, Volume: 35, Issue:1

    Topics: Benzoates; Chromatography, Thin Layer; Circadian Rhythm; Depression; Homovanillic Acid; Humans; Hydr

1974
[Characteristics of catecholamine metabolism in patients with endogenic depressions in the process of unloading-diet therapy].
    Vrachebnoe delo, 1974, Volume: 4

    Topics: Adult; Depression; Dopamine; Epinephrine; Fasting; Homovanillic Acid; Humans; Male; Norepinephrine;

1974
Toward a biochemical classification of depression.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Antidepressive Agents; Biogenic Amines; Brain; Brain Stem; Depression; Dopamine; Homovanillic Acid;

1974
Relationship of age and mood to monoamine metabolites in cerebrospinal fluid in parkinsonism.
    European journal of clinical pharmacology, 1974, Volume: 7, Issue:2

    Topics: Age Factors; Aged; Biogenic Amines; Depression; Dihydroxyphenylalanine; Emotions; Female; Homovanill

1974