Page last updated: 2024-09-28

Leg Length Inequality

A condition in which one of a pair of legs fails to grow as long as the other, which could result from injury or surgery.

Synonyms(1)

Synonym
Leg Length Inequality

Research

Studies (397)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990132 (33.25)23.3326
1990's71 (17.88)12.5806
2000's59 (14.86)18.1394
2010's57 (14.36)28.8240
2020's78 (19.65)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lactic acid0low10
pyruvic acid0low10
uracil0low10
amifostine anhydrous0low20
caffeine0low10
dantrolene0low10
diclofenac0low10
pentetic acid0low10
fentanyl0low10
gentamicin0low10
lamotrigine0low10
pentoxifylline0low20
succinylcholine0low10
thalidomide0low10
tranexamic acid0medium11
hydroxyproline0low10
apomorphine0low10
triamcinolone acetonide0medium11
6-methyluracil0low10
durapatite0low20
vancomycin0low20
triamcinolone hexacetonide0medium11
neodymium0low10
tantalum0low20
technetium0low40
titanium0low110
barium sulfate0low10
trolamine salicylate0medium162
melamine phosphate0low10
methotrexate0low10
technetium tc 99m pentetate0low10
cortisone0low10
metrizamide0low10
pyrophosphate0low10
fusidic acid0medium11
misoprostol0low20
strontium radioisotopes0low10
selenium0low20
radium0low10
calcitonin0low10
vendex0low40
tetracycline0low10
oxytetracycline, anhydrous0low20
transforming growth factor beta0low10

Protein Targets (530)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
estrogen-related nuclear receptor alpha6006
Carbonic anhydrase 10404
regulator of G-protein signaling 45005
arylsulfatase A4004
euchromatic histone-lysine N-methyltransferase 2150015
Bloom syndrome protein isoform 15005
muscarinic acetylcholine receptor M15005
Cellular tumor antigen p538008
D(3) dopamine receptor0517
Spike glycoprotein6006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, 2-oxoglutarate Oxygenase4004
Luciferase3003
acetylcholinesterase2002
phosphopantetheinyl transferase6006
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma8008
GLS protein4004
TDP1 protein8008
GLI family zinc finger 37007
Microtubule-associated protein tau5005
AR protein110011
aldehyde dehydrogenase 1 family, member A19009
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 33003
progesterone receptor5005
cytochrome P450 family 3 subfamily A polypeptide 48008
retinoic acid nuclear receptor alpha variant 16006
farnesoid X nuclear receptor4004
estrogen nuclear receptor alpha150015
cytochrome P450 2D67007
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma4004
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
thyroid stimulating hormone receptor4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x4004
cytochrome P450 2D6 isoform 12002
cellular tumor antigen p53 isoform a3003
cytochrome P450 2C19 precursor2002
cytochrome P450 2C9 precursor1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
vitamin D3 receptor isoform VDRA7007
potassium voltage-gated channel subfamily H member 2 isoform d5005
thyroid hormone receptor beta isoform 26006
mitogen-activated protein kinase 13003
nuclear factor erythroid 2-related factor 2 isoform 19009
nuclear receptor ROR-gamma isoform 14004
geminin120012
peripheral myelin protein 224004
cytochrome P450 3A4 isoform 12002
lethal factor (plasmid)2002
lamin isoform A-delta107007
Gamma-aminobutyric acid receptor subunit pi2002
Solute carrier family 22 member 1 0202
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40708
Voltage-dependent calcium channel gamma-2 subunit5005
Bile salt export pump012012
Integrin beta-33003
Integrin alpha-IIb3003
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0203
Tryptophan 5-hydroxylase 10101
D(2) dopamine receptor0327
5-hydroxytryptamine receptor 2A0202
Gamma-aminobutyric acid receptor subunit beta-12002
Alpha-1B adrenergic receptor0303
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
D0202
D(3) dopamine receptor0101
5-hydroxytryptamine receptor 1A0101
Alpha-2B adrenergic receptor0202
Glutamate receptor 25005
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
D(2) dopamine receptor0202
D(1A) dopamine receptor0226
D(4) dopamine receptor0315
D(1B) dopamine receptor0203
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Alpha-1D adrenergic receptor0303
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 2A0101
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
Gamma-aminobutyric acid receptor subunit alpha-62002
D(4) dopamine receptor0112
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 60101
5-hydroxytryptamine receptor 7 0202
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0101
Alpha-1A adrenergic receptor0303
Histamine H2 receptor2002
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0224
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
E3 ubiquitin-protein ligase Mdm20101
D0101
5-hydroxytryptamine receptor 4 0101
GABA theta subunit2002
Canalicular multispecific organic anion transporter 10707
D0202
ATPase family AAA domain-containing protein 55005
Ataxin-25005
Sigma non-opioid intracellular receptor 10303
Gamma-aminobutyric acid receptor subunit epsilon2002
5-hydroxytryptamine receptor 3B0101
ATP-dependent phosphofructokinase4004
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
glucocorticoid receptor [Homo sapiens]6006
retinoid X nuclear receptor alpha6006
pregnane X nuclear receptor5005
atrial natriuretic peptide receptor 1 precursor2002
chromobox protein homolog 16006
thyroid hormone receptor beta isoform a3003
DNA polymerase beta4004
DNA polymerase kappa isoform 14004
Potassium channel subfamily K member 20011
Glycogen phosphorylase, muscle form0101
Renin0101
Carbonic anhydrase 20314
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30101
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0202
Adenosine receptor A10203
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0203
Adenosine receptor A2b0203
Adenosine receptor A10114
Adenosine receptor A2a0204
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10314
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10314
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Guanine deaminase0101
bromodomain adjacent to zinc finger domain 2B3003
Solute carrier family 22 member 60202
Interferon beta2002
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Solute carrier family 15 member 20102
Solute carrier family 22 member 80101
endonuclease IV3003
dopamine D1 receptor3003
thioredoxin reductase6006
pregnane X receptor1001
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
peripheral myelin protein 22 isoform 14004
heat shock protein beta-12002
flap endonuclease 14004
survival motor neuron protein isoform d3003
M-phase phosphoprotein 83003
Glucocorticoid receptor0404
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 434004
Multidrug and toxin extrusion protein 10202
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90102
Prostaglandin G/H synthase 1 0101
Transient receptor potential cation channel subfamily A member 10011
Dihydrofolate reductase0304
Cytochrome c oxidase subunit 20101
Fatty acid-binding protein, liver0101
Transthyretin0013
Albumin0235
Prostaglandin G/H synthase 10202
Cytochrome P450 3A40101
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Cytochrome P450 2C9 0102
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60202
UDP-glucuronosyltransferase 1A1 0202
UDP-glucuronosyltransferase 1A40101
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 2 0101
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0101
Sodium- and chloride-dependent betaine transporter0101
Cytochrome P450 2J20101
Prostaglandin G/H synthase 20202
Prostaglandin G/H synthase 20101
Carbonic anhydrase 90101
Solute carrier family 22 member 60102
Prostaglandin G/H synthase 1 0101
Carbonic anhydrase 40101
P2Y purinoceptor 120101
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Nuclear receptor subfamily 1 group I member 20011
ATP-dependent translocase ABCB10101
Delta-type opioid receptor0202
Delta-type opioid receptor0303
Mu-type opioid receptor0314
Kappa-type opioid receptor0202
Histamine H1 receptor0101
Mu-type opioid receptor0213
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20202
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10202
Chain A, Type Iii Chloramphenicol Acetyltransferase0101
thioredoxin glutathione reductase3003
streptokinase A precursor0011
Bile salt export pump0303
Estrogen receptor0011
Guanine nucleotide-binding protein G1001
Estrogen receptor beta0011
Canalicular multispecific organic anion transporter 10203
large T antigen0101
Chain A, Cruzipain2002
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
GALC protein2002
EWS/FLI fusion protein5005
D(1A) dopamine receptor2002
nuclear factor erythroid 2-related factor 2 isoform 23003
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Dihydrofolate reductase0426
Potassium voltage-gated channel subfamily E member 10101
Sodium channel protein type 4 subunit alpha0102
Potassium voltage-gated channel subfamily KQT member 10101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, Ferritin light chain1001
acid sphingomyelinase1001
ClpP1001
15-lipoxygenase, partial2002
ATAD5 protein, partial4004
USP1 protein, partial3003
67.9K protein1001
Thymidylate synthase 0101
alpha-galactosidase1001
IDH13003
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 32002
importin subunit beta-1 isoform 13003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-13003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)3003
transactivating tegument protein VP16 [Human herpesvirus 1]0101
muscleblind-like protein 1 isoform 12002
histone acetyltransferase KAT2A isoform 13003
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80002
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110002
Protein-arginine deiminase type-40202
Chain A, Beta-lactamase3003
GTP-binding nuclear protein Ran isoform 11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
G1001
neuropeptide S receptor isoform A1001
HLA class I histocompatibility antigen, B alpha chain 1001
Inositol hexakisphosphate kinase 11001
cytochrome P450 2C9, partial1001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
WRN1001
Valosin-containing protein0101
apical membrane antigen 1, AMA11001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
lysosomal alpha-glucosidase preproprotein1001
microphthalmia-associated transcription factor isoform 90101
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase PLK11001
eukaryotic translation initiation factor 4E isoform 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Rap guanine nucleotide exchange factor 31001
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Serum paraoxonase/arylesterase 10101
phosphoglycerate kinase1001
thyroid stimulating hormone receptor2002
nonstructural protein 11001
NFKB1 protein, partial1001
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
Disintegrin and metalloproteinase domain-containing protein 171001
Inositol monophosphatase 11001
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Carbonic anhydrase0101
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Prolyl 4-hydroxylase0101
Solute carrier organic anion transporter family member 2A10101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
Muscarinic acetylcholine receptor M20101
72 kDa type IV collagenase0101
Stromelysin-10101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Alpha-synuclein0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Solute carrier family 22 member 70001
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0416
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
SMAD family member 21001
SMAD family member 31001
nuclear receptor subfamily 1, group I, member 21001
Chain A, Uracil-DNA Glycosylase0101
Alpha-2A adrenergic receptor0101
60 kDa heat shock protein, mitochondrial0101
Sodium-dependent serotonin transporter0101
10 kDa heat shock protein, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]