Page last updated: 2024-08-05 12:23:27
steroid acid
Any steroid substituted by at least one carboxy group.
ChEBI ID: 47891
Members (10)
| Member | Definition | Role |
|---|---|---|
| 3-hydroxy-5-cholestenoic acid | A steroid acid resulting from the oxidation of one of the terminal methyl groups of cholesterol to the corresponding aldehyde. | 3beta-hydroxycholest-5-en-26-oic acid |
| 3,7,12-trihydroxycholestan-26-oic acid | A steroid acid that is 5beta-cholestan-26-oic acid which is substituted by hydroxy groups as the 3alpha, 7alpha, and 12alpha positions. | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid |
| 3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a hydroxy group at position 3, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic, anticholinergic and antiserotonergic activities. | zhankuic acid B |
| 3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by hydroxy groups at positions 3 and 12, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha,12alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits antineoplastic activity. | zhankuic acid C |
| 4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acid | A steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a methyl group at position 4 and oxo groups at positions 3, 7 and 11 (the 4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic and anti-inflammatory activity. | zhankuic acid A |
| canrenoic acid | canrenoic acid | |
| epristeride | Epristeride | |
| fusidic acid | A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum. | fusidic acid |
| helvolic acid | A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24. | helvolic acid |
| koetjapic acid | Koetjapic acid |
Research
Studies (2,066)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 935 (45.26) | 18.7374 |
| 1990's | 320 (15.49) | 18.2507 |
| 2000's | 352 (17.04) | 29.6817 |
| 2010's | 375 (18.15) | 24.3611 |
| 2020's | 84 (4.07) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 177 (8.00%) | 5.53% |
| Reviews | 108 (4.88%) | 6.00% |
| Case Studies | 187 (8.45%) | 4.05% |
| Observational | 6 (0.27%) | 0.25% |
| Other | 1,735 (78.40%) | 84.16% |