An alpha,beta-unsaturated ketone of general formula R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the aldehydic C=O function is conjugated to a C#C triple bond at the alpha,beta position.
ChEBI ID: 51723
| Member | Definition | Role |
|---|---|---|
| acp-196 | A member of the class of imidazopyrazines that is imidazo[1,5-a]pyrazine substituted by 4-(pyridin-2-ylcarbamoyl)phenyl, (2S)-1-(but-2-ynoyl)pyrrolidin-2-yl, and amino groups at positions 1, 3 and 8, respectively. It is an irreversible second-generation Bruton's tyrosine kinase (BTK) inhibitor that is approved by the FDA for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. | acalabrutinib |
| capillin | capillin | |
| methylpentynol | methylpentynol |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 61 (21.71) | 18.7374 |
| 1990's | 3 (1.07) | 18.2507 |
| 2000's | 2 (0.71) | 29.6817 |
| 2010's | 59 (21.00) | 24.3611 |
| 2020's | 156 (55.52) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 40 (13.75%) | 5.53% |
| Reviews | 51 (17.53%) | 6.00% |
| Case Studies | 9 (3.09%) | 4.05% |
| Observational | 1 (0.34%) | 0.25% |
| Other | 190 (65.29%) | 84.16% |