| Assay ID | Title | Year | Journal | Article |
|---|
| AID44422 | Inhibitory concentration against butyrylcholinesterase from human serum | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID496881 | Inhibition of AChE | 2010 | Journal of medicinal chemistry, Aug-26, Volume: 53, Issue:16
| Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy. |
| AID314092 | Antagonist activity at muscarinic M2 receptor | 2008 | Journal of medicinal chemistry, Feb-14, Volume: 51, Issue:3
| Multi-target-directed ligands to combat neurodegenerative diseases. |
| AID345206 | Inhibition of human serum BChE by Ellman's assay | 2008 | Journal of medicinal chemistry, Nov-27, Volume: 51, Issue:22
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer. |
| AID141203 | Antagonistic potency against Muscarinic acetylcholine receptor M3 (10 uM) | 1998 | Journal of medicinal chemistry, Oct-22, Volume: 41, Issue:22
| Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. |
| AID314091 | Inhibition of human AchE | 2008 | Journal of medicinal chemistry, Feb-14, Volume: 51, Issue:3
| Multi-target-directed ligands to combat neurodegenerative diseases. |
| AID31637 | Selectivity towards acetylcholinesterase over butyrylcholinesterase | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID140900 | Antagonistic potency against Muscarinic acetylcholine receptor M1 (10 uM) | 1998 | Journal of medicinal chemistry, Oct-22, Volume: 41, Issue:22
| Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. |
| AID482894 | Inhibition of AChE | 2010 | European journal of medicinal chemistry, Mar, Volume: 45, Issue:3
| Prediction of acetylcholinesterase inhibitors and characterization of correlative molecular descriptors by machine learning methods. |
| AID1587208 | Inhibition of AChE (unknown origin) | 2019 | European journal of medicinal chemistry, May-01, Volume: 169 | Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease. |
| AID345207 | Inhibition of human recombinant AChE-induced amyloid beta (1-40) aggregation at 100 uM by thioflavin T formation assay | 2008 | Journal of medicinal chemistry, Nov-27, Volume: 51, Issue:22
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer. |
| AID142247 | Antagonistic potency of compound towards Muscarinic acetylcholine receptor M2 in guinea pig left atrium | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID31769 | Inhibitory activity on Acetylcholinesterase (AChE) from human erythrocytes | 2002 | Journal of medicinal chemistry, Jul-18, Volume: 45, Issue:15
| Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure. |
| AID1587209 | Inhibition of BuChE (unknown origin) | 2019 | European journal of medicinal chemistry, May-01, Volume: 169 | Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease. |
| AID25333 | Apparent dissociation constant of compound was evaluated; n.d. indicates not determined | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID44423 | Inhibition of Butyrylcholinesterase (BChE) of human erythrocytes [-log IC50 (uM)] | 1998 | Journal of medicinal chemistry, Oct-22, Volume: 41, Issue:22
| Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. |
| AID31620 | Inhibitory activity of compound against acetylcholinesterase from human erythrocytes | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID496880 | Inhibition of muscarinic M2 receptor | 2010 | Journal of medicinal chemistry, Aug-26, Volume: 53, Issue:16
| Polyamines in drug discovery: from the universal template approach to the multitarget-directed ligand design strategy. |
| AID141211 | Antagonist activity against Muscarinic acetylcholine receptor M3 of isolated Guinea Pig Longitudinal ileum | 2002 | Journal of medicinal chemistry, Jul-18, Volume: 45, Issue:15
| Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure. |
| AID31771 | Inhibitory concentration against acetylcholinesterase from human erythrocytes | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID142125 | Antagonistic potency against Muscarinic acetylcholine receptor M2 | 1998 | Journal of medicinal chemistry, Oct-22, Volume: 41, Issue:22
| Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. |
| AID31618 | Inhibition constant determined against Acetylcholinesterase (AChE) receptor. | 1998 | Journal of medicinal chemistry, Oct-22, Volume: 41, Issue:22
| Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. |
| AID44421 | Inhibitory activity against butyrylcholinesterase (BChE) in human erythrocyte | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Hexahydrochromeno[4,3-b]pyrrole derivatives as acetylcholinesterase inhibitors. |
| AID31768 | Inhibitory activity against acetylcholinesterase in human erythrocytes | 2001 | Journal of medicinal chemistry, Jan-04, Volume: 44, Issue:1
| Hexahydrochromeno[4,3-b]pyrrole derivatives as acetylcholinesterase inhibitors. |
| AID238797 | Competitive inhibition constant for Acetylcholinesterase | 2005 | Journal of medicinal chemistry, Jan-13, Volume: 48, Issue:1
| Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation. |
| AID345205 | Inhibition of human recombinant AChE by Ellman's assay | 2008 | Journal of medicinal chemistry, Nov-27, Volume: 51, Issue:22
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer. |
| AID79858 | Ability to reverse the D-tubocurarine-induced neuromuscular blockade in guinea pig left atrium | 2003 | Journal of medicinal chemistry, Mar-13, Volume: 46, Issue:6
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine. |
| AID345208 | Inhibition of self-induced amyloid beta (1-40) aggregation at 10 uM by thioflavin T formation assay | 2008 | Journal of medicinal chemistry, Nov-27, Volume: 51, Issue:22
| Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer. |
| AID142244 | Antagonist activity against Muscarinic acetylcholine receptor M2 of isolated Guinea Pig Left artium | 2002 | Journal of medicinal chemistry, Jul-18, Volume: 45, Issue:15
| Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure. |
| AID241279 | Inhibition of Acetylcholinesterase | 2005 | Journal of medicinal chemistry, Jan-13, Volume: 48, Issue:1
| Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation. |
| AID248321 | Inhibitory concentration against amyloid-beta aggregation; NA: Not active | 2005 | Journal of medicinal chemistry, Jan-13, Volume: 48, Issue:1
| Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation. |
| AID145841 | Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated Torpedo | 2002 | Journal of medicinal chemistry, Jul-18, Volume: 45, Issue:15
| Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure. |
| AID241298 | Inhibition of Butyrylcholinesterase | 2005 | Journal of medicinal chemistry, Jan-13, Volume: 48, Issue:1
| Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation. |
| AID31775 | Inhibition of acetylcholinesterase (AChE) of human erythrocytes | 1998 | Journal of medicinal chemistry, Oct-22, Volume: 41, Issue:22
| Acetylcholinesterase noncovalent inhibitors based on a polyamine backbone for potential use against Alzheimer's disease. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |