Member | Definition | Role |
9-arabinofuranosylguanine | A purine nucleoside in which guanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. It inhibits DNA synthesis and causes cell death. | 9-beta-D-arabinofuranosylguanine |
cytarabine | A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties. | cytarabine |
nelarabine | A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G). | nelarabine |
vidarabine | A purine nucleoside in which adenine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. | adenine arabinoside |