Roles > GHB receptor agonist
Page last updated: 2024-08-05 15:32:30

GHB receptor agonist

A drug that binds to and activates gamma-hydroxybutyric acid receptors.

ChEBI ID: 53353

Members (1)

MemberDefinitionClass
4-hydroxybutyric acidA 4-hydroxy monocarboxylic acid that is butyric acid in which one of the hydrogens at position 4 is replaced by a hydroxy group.4-hydroxybutyric acid

Research

Studies (434)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-199027 (6.22)18.7374
1990's22 (5.07)18.2507
2000's200 (46.08)29.6817
2010's147 (33.87)24.3611
2020's38 (8.76)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials14 (3.02%)5.53%
Reviews48 (10.37%)6.00%
Case Studies55 (11.88%)4.05%
Observational1 (0.22%)0.25%
Other345 (74.51%)84.16%

Protein Targets (20)

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)Ki4.300011
Calcium/calmodulin-dependent protein kinase type II subunit alphaRattus norvegicus (Norway rat)Ki19.433333
GABA theta subunitRattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Ki502.150022
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Ki502.150022
Proton-coupled amino acid transporter 1Homo sapiens (human)Ki65,000.000011
TetraspaninRattus norvegicus (Norway rat)IC5015.800022
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