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terminal acetylenic compound

An acetylenic compound which a carbon of the C#C moiety is attached to a hydrogen atom.

ChEBI ID: 73477

Members (35)

MemberDefinitionRole
10-propargyl-10-deazaaminopterinA pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma.pralatrexate
17-octadecynoic acidAn acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid.octadec-17-ynoic acid
acetyleneacetylene
clorgylineAn aromatic ether that is the 2,4-dichlorophenyl ether of 3-aminopropan-1-ol in which the nitrogen is substituted by a methyl group and a prop-1-yn-3-yl group. A monoamine oxidase inhibitor, it was formerly used as an antidepressant.clorgyline
danazoldanazol
desogestreldesogestrel
erlotinibA quinazoline compound having a (3-ethynylphenyl)amino group at the 4-position and two 2-methoxyethoxy groups at the 6- and 7-positions.erlotinib
erlotinib hydrochlorideThe hydrochloride salt of erlotinib.erlotinib hydrochloride
ethinamateA carbamate ester that is the 1-vinylcyclohexyl ester of carbamic acid. A short-acting sedative-hypnotic, it was formerly used to treat insomnia.ethinamate
ethinyl estradiolA 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.17alpha-ethynylestradiol
ethisteroneA 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.ethisterone
ethyl propiolateThe ethyl ester of prop-2-ynoic acid.ethyl propiolate
ethynodiolethynodiol
ethynodiol diacetateethynodiol diacetate
etonogestreletonogestrel
levonorgestrellevonorgestrel
mandipropamidA monocarboxylic acid amide resulting from the condensation of the carboxy group of p-chloromandelic acid propargyl ether with the amino group of 2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethylamine.2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide
mestranolA terminal acetylenic compound that is (17alpha)-17-ethynylestra-1(10),2,4-triene substituted by a methoxy group at position 3 and a hydroxy group at position 17.mestranol
methylacetylenepropyne
norethindroneA 17beta-hydroxy steroid that is testosterone in which the hydrogen at position 17 is replaced by an ethynyl group and in which the methyl group attached to position 10 is replaced by hydrogen.norethisterone
norethindrone acetateA 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester.norethisterone acetate
norgestimatenorgestimate
pronamideA member of the class of benzamides resulting from the formal condensation of the carboxy group of 3,5-dichlorobenzoic acid with the amino group of 2-methylbut-3-yn-2-amine. It is used as a systemic post-emergent herbicide for the control grass and broadleaf weeds in a wide range of in a wide variety of fruit and root crops.propyzamide
propargitepropargite
propargyl alcoholA terminal acetylenic compound that is prop-2-yne substituted by a hydroxy group at position 1.prop-2-yn-1-ol
propiolaldehydeprop-2-ynal
propiolic acidA terminal acetylenic compound that is a 3-carbon, straight-chain, monounsaturated fatty acid having one acetylenic bond.propynoic acid
quinestrolquinestrol
rasagilineAn indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.rasagiline
s 23121A dicarboximide that is 4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione in which the nitrogen has been substituted by a 5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl group.2-[5-(but-3-yn-2-yloxy)-4-chloro-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
s 53482A benzoxazine that is N-(prop-2-yn-1-yl)-2H-1,4-benzoxazin-3(4H)-one which is substituted at position 6 by a 1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl group and at position 7 by a fluorine. A protoporphyrinogen oxidase inhibitor, it is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops.flumioxazin
selegiline(-)-selegiline
selegiline hydrochloride, (r)-isomerselegiline hydrochloride
tiboloneEstran-3-one with a double bond between positions 5 and 10, and bearing both an ethynyl group and a hydroxy group at position 17 (R-configuration). A synthetic steroid hormone drug which acts as an agonist at all five type I steroid hormone receptors, it is used in the prevention of postmenopausal osteoporosis and for treatment of endometriosis.tibolone
zr 777kinoprene

Research

Studies (31,116)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19909,763 (31.38)18.7374
1990's4,617 (14.84)18.2507
2000's6,714 (21.58)29.6817
2010's8,084 (25.98)24.3611
2020's1,938 (6.23)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials6,538 (16.34%)5.53%
Reviews3,441 (8.60%)6.00%
Case Studies2,694 (6.73%)4.05%
Observational160 (0.40%)0.25%
Other27,177 (67.93%)84.16%