Conditions > Fluorosis, Dental
Page last updated: 2024-09-27

Fluorosis, Dental

A chronic endemic form of hypoplasia of the dental enamel caused by drinking water with a high fluorine content during the time of tooth formation, and characterized by defective calcification that gives a white chalky appearance to the enamel, which gradually undergoes brown discoloration. (Jablonski's Dictionary of Dentistry, 1992, p286)

Synonyms(1)

Synonym
Fluorosis, Dental

Research Excerpts

Overview

ExcerptReference
"Dental fluorosis is not a public health problem in East York, but parents should be advised to supervise toothbrushing by children under 2 years of age."( Chipman, ML; Leake, JL; Levine, N; Locker, D; Nikiforuk, G; Osuji, OO, 1988)
"Five expressions of dental fluorosis are described in cattle exposed to industrial fluoride pollution: 1."( Krook, L; Lillie, JH; Maylin, GA; Wallace, RS, 1983)
"However, dental fluorosis is a reflection of fluoride exposure only during the time of enamel formation, somewhat limiting its use as a biomarker."( Den Besten, PK, 1994)
"Mild dental fluorosis is frequently linked to fluoridated water, but discretionary fluoride sources may also be important."( Riordan, PJ, 1993)
"Dental fluorosis is endemic in Eastern Africa and a high prevalence has been found even in low-fluoride (approximately 0."( Affan, AA; Bjorvatn, K; Ibrahim, YE, 1995)
"Endemic dental fluorosis is a form of enamel hypoplasia characterized by moderate-to-severe staining of the tooth surface."( Erdogan, G, 1998)
"The incidence of dental fluorosis is best correlated with the total cumulative fluoride exposure to the developing dentition."( DenBesten, PK, 1999)
"The level of dental fluorosis is comparable with a naturally occurring fluoride level in water of between 1-2 ppm."( Littleton, J, 1999)
"Dental fluorosis is common in individuals exposed to different sources of fluoride during tooth development."( Cury, JA; de Souza, AP; Gerlach, RF; Line, SR, 2000)
"Dental fluorosis is closely associated with fluoride intake during the period of tooth development."( Ekstrand, J; Fomon, SJ; Ziegler, EE, 2000)
"The prevalence of dental fluorosis is on the increase in different parts of the world, even in areas with fluoride-deficient public water supplies."( Akpata, ES, 2001)
"Dental fluorosis is an endemic dental health problem around the world; so, it is important to develop clinical alternatives that are non-invasive and inexpensive."( Berumen-Maldonado, R; Hernandez-Hernandez, F; Loyola-Rodriguez, JP; Patiño-Marin, N; Pozos-Guillen, Ade J, 2003)
"Dental fluorosis is a major dental public health problem among children in Davangere district and is related to drinking water with 0."( Anuradha, KP; Chandrashekar, J, 2004)
"Dental fluorosis is defined by an alteration of dental hard tissues and occurs when fluoride intakes are excessive."( Arbab Chirani, R; Foray, H, 2005)
"Dental fluorosis is the sole risk of fluoride use, but it is not a fate."( Arbab Chirani, R; Foray, H, 2005)
"Dental fluorosis is a condition of enamel hypomineralization due to the effects of excessive fluoride on ameloblasts during enamel formation."( Manton, DJ; Ng, F, 2007)
"Dental fluorosis is known to occur in some parts of Plateau State, but the factors responsible for its occurrence are unknown."( Akosu, TJ; Zoakah, AI, 2008)
"Mild-to-moderate dental fluorosis is a significant side effect."( Hasson, H; Ismail, AI, 2008)
"One way to reduce dental fluorosis is by reducing the fluoride (F) concentration in dentifrice, but low-F dentifrice should be as effective as a standard dentifrice."( Castro, LP; Delbem, AC; Sassaki, KT; Takeshita, EM, 2009)
"Dental fluorosis is dependent on local fluoride levels in the extra cellular fluid surrounding the tooth during its development."( Cury, JA; Ellwood, RP, 2009)
"Chronic endemic dental fluorosis is a malformation of teeth caused by excessive ingestion of fluoride during period of tooth development."( Ichinose, S; Nikaido, T; Tagami, J; Tay, F; Waidyasekera, K; Watanabe, A; Weerasinghe, D, 2010)
"Dental fluorosis is a major public health problem in 17 states of India."( Chandrashekar, J; Sundaram, KR; Thankappan, KR, 2010)
"The severity of dental fluorosis is also dependent upon fluoride dose and the timing and duration of fluoride exposure."( Everett, ET, 2011)
"As dental fluorosis is very common (in about one-fourth) among the middle school children, in this resettlement colony of Delhi, various control measures e."( Kaur, S; Sodhi, A; Tiwari, P, 2010)
"In this area, dental fluorosis is an endemic disease."( Marimon, MP; Roisenberg, A; Suhogusoff, AV; Viero, AP, 2013)
"Dental fluorosis is characterized by subsurface hypomineralization and increased porosity of enamel, associated with a delay in the removal of enamel matrix proteins."( Den Besten, PK; Ho, S; Horst, O; Kim, JY; Nakano, Y; Radlanski, RJ; Zhang, Y; Zhu, L, 2014)
"Dental fluorosis is characterized by subsurface hypomineralization and retention of enamel matrix proteins."( Antone, JV; Bartlett, JD; Everett, ET; Sierant, ML; Suzuki, M; Whitford, GM, 2014)
"A clear risk of dental fluorosis is apparent in infants and children of the study area."( Ali, MM; Bhattacharya, P; Mallick, A; Pyne, J; Samal, AC; Santra, SC, 2015)
"Assessment of dental fluorosis is typically undertaken by clinical examiners in epidemiological studies."( Ellwood, RP; Goodwin, M; Liu, Z; McGrady, M; Pretty, IA, 2018)
"Dental fluorosis is an undesirable side effect of too much fluoride ingestion during the early years of life."( Connett, M; Kanter, V; Limeback, H; Neurath, C; Osmunson, B; Wells, CR, 2019)
"Dental fluorosis is a developmental defect that results in hypo-mineralization and pronounced porosity of enamel in the affected individuals."( Goswami, R; Majumdar, KK; Pramanik, S; Saha, D; Sikdar, N, 2021)
"Dental fluorosis is the most common and prominent symptom in the early stage of chronic fluorosis, which is caused by excessive fluorine intake during tooth development."( Gu, LS; Ling, JQ; Wei, X, 2020)
"Dental fluorosis is endemic in the Rift Valley in Africa, especially around volcanic areas, due to the high fluoride content in daily drinking water."( Brunet-Llobet, L; Lahor-Soler, E; Mahande, MJ; Mashala, EI; Miranda-Rius, J; Mrina, O, 2020)
"Dental fluorosis is an increasing problem due to over exposure to fluoride from the environment."( Fried, D; Kashirtsev, F; Simon, JC; Tressel, J, 2021)
"Dental fluorosis is an irreversible condition caused by excessive fluoride consumption during tooth formation and is considered a public health problem in several world regions."( Irigoyen-Camacho, ME; Mejía-Gózalez, AM; Picquart, M; Zepeda-Zepeda, MA, 2021)

Context

ExcerptReference
"The milder forms of dental fluorosis have increased in prevalence since the original epidemiologic surveys of the 1930s."( Newbrun, E, 1999)
"Extensive dental fluorosis has been observed in the population exposed to drinking water of high fluoride content."( Asmellash, M; Fisahatsion, A; Kahsai, F; Srikanth, R; Viswanatham, KS, 2002)
"Dental fluorosis has been associated with consumption of fluoride-contaminated foliage by juvenile livestock and wildlife in Europe and North America."( Coulson, G; Death, C; Hufschmid, J; Kierdorf, H; Kierdorf, U; Morris, WK, 2015)
"Dental fluorosis has recently been diagnosed in wild marsupials inhabiting a high-fluoride area in Victoria, Australia."( Death, C; Hufschmid, J; Kierdorf, H; Kierdorf, U; Witzel, C, 2016)
"Dental fluorosis has been assessed only 3 times in nationally representative oral health surveys in the United States."( Connett, M; Kanter, V; Limeback, H; Neurath, C; Osmunson, B; Wells, CR, 2019)
"The prevalence of dental fluorosis has an upward trend arround the world, thus certain public prevention and treatment strategies need to be taken."( Gu, LS; Ling, JQ; Wei, X, 2020)
"Dental fluorosis has been reported in many sub-Saharan African countries including South Africa, Tanzania, Uganda, Ethiopia, Kenya, Sudan, Niger, Nigeria, Benin, Ghana and Malawi."( Edokpayi, JN; Odiyo, JO; Onipe, T, 2020)

Actions

ExcerptReference
"The fraction of dental fluorosis-affected children varied from 30% to 94."( Kataria, SK; Kumar, S; Lata, S; Yadav, JP, 2009)
"Dental fluorosis affects the quality of life."( Aceituno-Antezana, O; Astudillo-Rozas, W; Chimenos-Küstner, E; García-Escobar, TM; Lozano de Luaces, V; Manzanares-Céspedes, MC; Valdivia-Gandur, I; Yamadala, B, 2022)

Research

Studies (1,663)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990537 (32.29)23.3326
1990's302 (18.16)12.5806
2000's296 (17.80)18.1394
2010's404 (24.29)28.8240
2020's124 (7.46)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low10
chlorine0medium41
hydrochloric acid0medium273
gallic acid0low10
trimetaphosphoric acid0low10
cytosine0low10
dimethyl sulfoxide0low20
formaldehyde0low10
hydrogen carbonate0low60
iodine0low90
melatonin0low10
niacinamide0low10
nitrates0low20
hydroxide ion0low20
phosphoric acid0medium143
uric acid0low10
urea0medium134
aluminum fluoride0low10
caffeine0low20
ether0medium21
fipronil0low10
fpl 641760low10
glutethimide0low10
guanidine0low10
hexobarbital0low10
hydrochlorothiazide0low10
2-propanol0low10
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one0low10
nifedipine0low20
phenobarbital0low10
potassium chloride0low10
resorcinol0low10
hydroxyproline0low10
thyroxine0low10
triiodothyronine0low10
serine0low10
sucrose0low10
edetic acid0low50
phencyclidine0low20
isoprene0low10
bisphenol a0low10
pyrroles0low10
pyrazolanthrone0low10
flurothyl0low10
perfluorooctanoic acid0low10
silicon carbide0medium41
limestone0medium31
magadi soda0low40
malondialdehyde0low80
c.i. 425100low10
hydroxyethyl methacrylate0medium11
durapatite0low30
potassium hydroxide0low10
hydrofluoric acid0low20
bisphenol a-glycidyl methacrylate0medium41
sabinene0low10
carbonates0low100
sodium metasilicate0medium11
manganese0low20
mercury0low20
molybdenum0low20
titanium0low10
cadmium0low30
chromium0low10
uranium0low10
zirconium0low10
magnesium sulfate0low10
tricalcium phosphate0low50
fluorine0low1070
chlorine0low20
beryllium fluoride0low10
calcium pyrophosphate0low10
sodium selenite0low10
trolamine salicylate0low20
ammonium fluoride0low10
ammonium chloride0low10
fluorides0medium1,35217
phenyl acetate0low10
cetylpyridinium chloride anhydrous0low50
carbamide peroxide0medium124
transferrin0low10
calcium oxalate0low10
glutamic acid0low20
adenosine diphosphate ribose0low10
amoxicillin0low50
1-carboxyglutamic acid0low10
atorvastatin0low10
coomassie brilliant blue r0low10
sodium molybdate(vi)0low10
dolomite0low10
trazodone hydrochloride0low10
glucose, (beta-d)-isomer0low10
5-methylcytosine0low10
fluorophosphate0medium242
deoxypyridinoline0low10
gastrodin0low10
caprylates0low10
glycerophosphoinositol 4,5-bisphosphate0low10
proline0low10
silver fluoride0low40
organophosphonates0low10
n-acetylneuraminic acid0low20
strychnine0medium11
brucine0medium11
cyclopamine0low20
tretinoin0low10
resveratrol0low10
lycopene0low20
sodium bicarbonate0low30
potassium fluoride0low20
bromochloroacetic acid0low10
pyrophosphate0low40
pica0low20
nitrogen dioxide0low10
dermatan sulfate0low20
calcium sucrose phosphate0low10
osteoprotegerin0low10
vitamin k semiquinone radical0low10
beta carotene0low10
cholecalciferol0medium11
zeaxanthin0low10
lutein0low10
casein kinase ii0low10
lead0low40
tin0low10
barium0low10
aluminum0low90
strontium0low30
arsenic0low140
sulfur0low10
beryllium0low10
cysteine0low10
cerotate0low10
silicon0low10
phosphorus0low150
boron0low20
selenium0low80
chlorhexidine0low10
mocetinostat0low20
aluminum oxide0low10
fluorapatite0low20
granite0low20
cytochrome c-t0low20
sodium borate0low10
cryolite0low10
sodium hypochlorite0medium91
superphosphate0low40
heparitin sulfate0low10
ascorbic acid0medium41
tetracycline0medium221
minocycline0low20
clay0low40
transforming growth factor beta0low10
rome0low10
caseins0low40
feldspar0low10
lactoferrin0low10
chondroitin sulfates0low40
exudates0low90
guanine0low10
neopterin0low10
amido black0low10
concanavalin a0low10
phosphorus radioisotopes0low10

Protein Targets (1,036)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, HADH2 protein100010
Chain B, HADH2 protein100010
Chain A, 2-oxoglutarate Oxygenase100010
Chain A, Cruzipain6006
Chain A, Methyltransferase Wbdd0101
thioredoxin reductase120012
15-lipoxygenase, partial3003
ATAD5 protein, partial8008
NFKB1 protein, partial4004
TDP1 protein260026
Thrombopoietin4004
aldehyde dehydrogenase 1 family, member A1160016
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
thyroid stimulating hormone receptor7007
regulator of G-protein signaling 47007
EWS/FLI fusion protein7007
67.9K protein9009
Parkin7007
euchromatic histone-lysine N-methyltransferase 2200020
cytochrome P450 2D6 isoform 16006
cellular tumor antigen p53 isoform a6006
cytochrome P450 2C19 precursor4004
cytochrome P450 2C9 precursor6006
chromobox protein homolog 1140014
flap endonuclease 13003
serine/threonine-protein kinase mTOR isoform 15005
survival motor neuron protein isoform d100010
cytochrome P450 3A4 isoform 1130013
M-phase phosphoprotein 86006
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0102
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha0101
Serine/threonine-protein kinase PLK40112
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0101
Gamma-aminobutyric acid receptor subunit pi130114
Polyunsaturated fatty acid lipoxygenase ALOX15B5005
Bromodomain-containing protein 40101
5-hydroxytryptamine receptor 40404
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Integrin beta-36017
Cytochrome P450 1A20415
Integrin alpha-IIb6017
Neuronal acetylcholine receptor subunit alpha-40202
Serine/threonine-protein kinase pim-10101
Neuronal acetylcholine receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit beta-1130114
Gamma-aminobutyric acid receptor subunit delta130114
Gamma-aminobutyric acid receptor subunit gamma-2130114
Casein kinase II subunit alpha'0303
Gamma-aminobutyric acid receptor subunit alpha-5130114
Gamma-aminobutyric acid receptor subunit alpha-3130114
Gamma-aminobutyric acid receptor subunit gamma-1130114
Gamma-aminobutyric acid receptor subunit alpha-2130114
Proteinase-activated receptor 10001
Bromodomain-containing protein 20101
Phosphatidylinositol 3-kinase regulatory subunit alpha0102
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0404
Gamma-aminobutyric acid receptor subunit alpha-4130114
Gamma-aminobutyric acid receptor subunit gamma-3130114
Gamma-aminobutyric acid receptor subunit alpha-6130114
Sodium-dependent serotonin transporter0506
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0101
Type-1 angiotensin II receptor0101
5-hydroxytryptamine receptor 2B0404
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0203
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0103
Serine/threonine-protein kinase mTOR0202
Serine/threonine-protein kinase mTOR0101
Histamine H2 receptor8008
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0203
Glycogen synthase kinase-3 beta0101
D(1A) dopamine receptor3003
Serine/threonine-protein kinase PLK10202
Gamma-aminobutyric acid receptor subunit alpha-1130114
Gamma-aminobutyric acid receptor subunit beta-3130114
Gamma-aminobutyric acid receptor subunit beta-2130114
Casein kinase II subunit beta0303
Casein kinase II subunit alpha0303
DNA-dependent protein kinase catalytic subunit0303
Mu-type opioid receptor0202
Serine-protein kinase ATM0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
Serine/threonine-protein kinase ATR0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Bromodomain-containing protein 30101
Serine/threonine-protein kinase pim-30101
Phosphoinositide 3-kinase regulatory subunit 50101
GABA theta subunit130114
Gamma-aminobutyric acid receptor subunit epsilon130114
Serine/threonine-protein kinase PLK30202
Serine/threonine-protein kinase PLK20101
ATP-dependent phosphofructokinase110011
hypoxia-inducible factor 1 alpha subunit9009
RAR-related orphan receptor gamma270027
GLI family zinc finger 3280028
AR protein340034
retinoic acid nuclear receptor alpha variant 1270027
retinoid X nuclear receptor alpha250025
estrogen nuclear receptor alpha390039
peroxisome proliferator-activated receptor delta140014
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a210021
activating transcription factor 67007
v-jun sarcoma virus 17 oncogene homolog (avian)140014
Histone H2A.x9009
thyroid hormone receptor beta isoform a120012
heat shock protein beta-19009
nuclear factor erythroid 2-related factor 2 isoform 1270027
lamin isoform A-delta10190019
Voltage-dependent calcium channel gamma-2 subunit180018
Glutamate receptor 2182121
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE130013
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
nuclear receptor subfamily 1, group I, member 3220022
cytochrome P450 family 3 subfamily A polypeptide 4150015
glucocorticoid receptor [Homo sapiens]280028
estrogen-related nuclear receptor alpha330033
pregnane X nuclear receptor230023
nuclear factor erythroid 2-related factor 2 isoform 26006
importin subunit beta-1 isoform 15005
snurportin-15005
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 14004
Bile salt export pump013013
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 433003
Protein mono-ADP-ribosyltransferase PARP150303
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 5110011
Ataxin-2110011
Transient receptor potential cation channel subfamily M member 20011
Chain A, Beta-lactamase6006
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
apical membrane antigen 1, AMA13003
Beta-lactamase 0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
DNA polymerase eta isoform 14004
DNA polymerase iota isoform a (long)8008
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
DNA polymerase kappa isoform 1110011
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40808
Bile salt export pump0202
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Cytochrome P450 2C9 0516
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
Solute carrier family 15 member 10101
Cytochrome P450 2J20404
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Canalicular multispecific organic anion transporter 10707
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase8008
thioredoxin glutathione reductase3003
vitamin D (1,25- dihydroxyvitamin D3) receptor140014
IDH16006
thyroid hormone receptor beta isoform 2240024
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin240024
lethal factor (plasmid)9009
Polyphenol oxidase 20305
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0303
Alpha-2B adrenergic receptor0011
Spike glycoprotein6006
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
SMAD family member 27007
SMAD family member 37007
caspase 7, apoptosis-related cysteine protease8008
estrogen receptor 2 (ER beta)100010
peroxisome proliferator activated receptor gamma170017
caspase-38008
Caspase-73003
vitamin D3 receptor isoform VDRA100010
caspase-33003
Solute carrier organic anion transporter family member 2B1 0001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
Cellular tumor antigen p53220022
ATP-dependent translocase ABCB10304
Insulin receptor 0101
Dipeptidyl peptidase 40101
Prostaglandin G/H synthase 20202
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Histone deacetylase 10303
Histone deacetylase 20303
Solute carrier organic anion transporter family member 1B30204
Histone deacetylase 60202
Broad substrate specificity ATP-binding cassette transporter ABCG20303
Solute carrier organic anion transporter family member 1B10306
core protein, partial0101
peripheral myelin protein 22100010
histone acetyltransferase KAT2A isoform 16006
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Luciferase9009
glp-1 receptor, partial6006
GALC protein1001
GLS protein9009
progesterone receptor150015
farnesoid X nuclear receptor140014
G100010
cytochrome P450 2D67007
aryl hydrocarbon receptor140014
thyroid stimulating hormone receptor9009
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
potassium voltage-gated channel subfamily H member 2 isoform d7007
GTPase KRas0011
Interferon beta110011
HLA class I histocompatibility antigen, B alpha chain 100010
Estrogen receptor0314
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Aldo-keto reductase family 1 member B10404
Androgen receptor0202
Polyunsaturated fatty acid lipoxygenase ALOX150202
Androgen receptor0202
Sodium-dependent noradrenaline transporter 0617
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 60202
Nuclear receptor ROR-gamma91111
Estrogen-related receptor gamma0101
Sodium-dependent dopamine transporter 0404
GTP-binding protein Rheb0011
Inositol hexakisphosphate kinase 1100010
Estrogen receptor beta0112
cytochrome P450 2C9, partial100010
TSHR protein1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Alpha-synuclein2406
Muscarinic acetylcholine receptor M10102
Taste receptor type 2 member 100024
nuclear receptor subfamily 1, group I, member 22002
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0022
Chain A, glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Chitinase0101
phosphopantetheinyl transferase9009
atrial natriuretic peptide receptor 1 precursor2002
DNA polymerase beta3003
nuclear receptor ROR-gamma isoform 1100010
muscarinic acetylcholine receptor M15005
Potassium channel subfamily K member 20022
Glycogen phosphorylase, muscle form0202
Renin0202
Carbonic anhydrase 1018019
Carbonic anhydrase 2020122
Cholinesterase0303
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30505
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0303
Adenosine receptor A10304
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A30101
Adenosine receptor A2a0315
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10518
Adenosine receptor A2a0406
Vasopressin V2 receptor0001
Adenosine receptor A2a0101
Adenosine receptor A10101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0224
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Guanine deaminase0203
Chain A, Beta-lactoglobulin0011
Chain A, Beta-lactoglobulin0011
UDP-3-O-acyl-N-acetylglucosamine deacetylase0011
Carbonic anhydrase 4015015
Carbonic anhydrase010010
Carbonic anhydrase 150707
Chain A, Protein kinase CK2, alpha Subunit0101
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT0101
Chain A, Protein Kinase Ck2, Alpha Subunit0101
Chain A, Ferritin light chain8008
endonuclease IV3003
dopamine D1 receptor1001
arylsulfatase A5005
Bloom syndrome protein isoform 16006
NPC intracellular cholesterol transporter 1 precursor3003
peripheral myelin protein 22 isoform 17007
mitogen-activated protein kinase 17007
ras-related protein Rab-9A3003
Serine/threonine-protein kinase Sgk10101
Ribosyldihydronicotinamide dehydrogenase [quinone]0527
Casein kinase II subunit alpha 0101
Cyclin-A20101
Cyclin-dependent kinase 20112
Casein kinase II subunit beta0101
Cyclin-A10101
Dual specificity mitogen-activated protein kinase kinase 10101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Ribosomal protein S6 kinase alpha-10101
Casein kinase II subunit alpha 30202
Single-stranded DNA cytosine deaminase2002
USP1 protein, partial110011
Microtubule-associated protein tau8008
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
thyrotropin-releasing hormone receptor2002
Caspase-20011
Inositol monophosphatase 13003
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, BCL-2-RELATED PROTEIN A10011
acid sphingomyelinase3003
interleukin 86006
PAX80001
pregnane X receptor3003
PINK11001
glucocerebrosidase3003
heat shock protein 900011
calcineurin A1, putative0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50202
perilipin-10202
transcriptional regulator ERG isoform 31001
huntingtin isoform 22002
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 11012
protein AF-9 isoform a0001
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0202
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
Synaptojanin-20101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
Synaptojanin-10101
Solute carrier family 22 member 30303
Glutathione reductase, mitochondrial0506
72 kDa type IV collagenase0303
Matrix metalloproteinase-90202
Trypanothione reductase0101
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 42002
Multidrug and toxin extrusion protein 10101
Spermine oxidase0101
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Vitamin D3 receptor0114
Glycine receptor subunit alpha-10213
Vitamin D3 receptor0011
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Amyloid-beta precursor protein0415
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10112
5-hydroxytryptamine receptor 2C0202
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0404
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit gamma-20303
D0101
5-hydroxytryptamine receptor 1A0203
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Liver carboxylesterase 10001
Sodium-dependent dopamine transporter0202
Gamma-aminobutyric acid receptor subunit beta-30303
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50303
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30303
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Glutamate receptor ionotropic, NMDA 1 0617
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0202
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit beta-20303
Gamma-aminobutyric acid receptor subunit alpha-40303
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0303
Glutamate receptor ionotropic, NMDA 2A 0516
Glutamate receptor ionotropic, NMDA 2B0516
Glutamate receptor ionotropic, NMDA 2C0517
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0102
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Potassium voltage-gated channel subfamily H member 20404
Leukotriene B4 receptor 10102
Gamma-aminobutyric acid receptor subunit alpha-60303
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0516
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10303
Glutamate receptor ionotropic, NMDA 3B0516
Sigma non-opioid intracellular receptor 10303
Gamma-aminobutyric acid receptor subunit gamma-30303
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20102
Glutamate receptor ionotropic, NMDA 3A0516
Gamma-aminobutyric acid receptor subunit theta0303
Transporter0202
Carbonic anhydrase 5A, mitochondrial010010
Carbonic anhydrase 9011112
Integrin beta-10202
Integrin alpha-40202
Smoothened homolog0101
Sonic hedgehog protein0101
Sonic hedgehog protein0112
Smoothened homolog0213
Deoxycytidine kinase0001
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Eyes absent homolog 20202
Angiotensin-converting enzyme 0303
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
histone deacetylase 9 isoform 33003
nonstructural protein 13003
neuropeptide S receptor isoform A2002
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
hypothetical protein, conserved2002
fructose-bisphosphate aldolase A1001
glyceraldehyde-3-phosphate dehydrogenase isoform 11001
Carbonic anhydrase 120404
Pancreatic triacylglycerol lipase0101
Urokinase-type plasminogen activator0101
Tissue-type plasminogen activator0101
Plasminogen activator inhibitor 10101
Urokinase-type plasminogen activator0101
Carbonic anhydrase 30404
Matrilysin0202
L-selectin0101
P-selectin0101
E-selectin0101
Prolyl 4-hydroxylase subunit alpha-10202
Carbonic anhydrase 60606
Dipeptidyl peptidase 40202
Proteasome subunit beta type-50101
Nitric oxide synthase, inducible0202
Carbonic anhydrase 70606
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT60101
Squalene monooxygenase 0101
Autoinducer 2-binding periplasmic protein LuxP0101
Anthrax toxin receptor 20101
Disintegrin and metalloproteinase domain-containing protein 170101
Lactoperoxidase0001
Polypeptide N-acetylgalactosaminyltransferase 20112
Alpha-(1,3)-fucosyltransferase 70101
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 10101
Carbonic anhydrase0202
Reverse transcriptase/RNaseH 0101
Carbonic anhydrase 130505
Toll-like receptor 2 0101
Carbonic anhydrase 140404
Carbonic anhydrase 5B, mitochondrial0707
Succinate-semialdehyde dehydrogenase, mitochondrial0101
4-aminobutyrate aminotransferase, mitochondrial0101
Asialoglycoprotein receptor 10112
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0202
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0022
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10213
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0303
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0202
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Solute carrier family 22 member 10203
Solute carrier family 22 member 20203
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Carbonic anhydrase 0202
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase0202
Carbonic anhydrase 0303
Hsf1 protein0011
Carbonic anhydrase 0101
Solute carrier family 22 member 60101
Albumin0112
Delta-type opioid receptor0102
Delta-type opioid receptor0101
Mu-type opioid receptor0404
Guanine nucleotide-binding protein G2002
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Neutral amino acid transporter A0303
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0303
Proton-coupled amino acid transporter 10303
Amino acid transporter0303
Chymotrypsinogen A0101
retinoic acid receptor alpha isoform 10101
retinoic acid receptor RXR-alpha isoform a0101
ClpP2002
Cytochrome P450 1A10202
Cytochrome P450 1A2 0101
Myeloperoxidase0101
Cytochrome P450 2C11 0101
Cytochrome P450 2D60213
Aromatase0303
Acetylcholinesterase 0101
Nociceptin receptor0202
Alpha-1A adrenergic receptor0606
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20013
Cytochrome P450 1B10303
Carboxylic ester hydrolase 0101
Histamine H3 receptor0101
Stromelysin-10202
Multidrug transporter MdfA0202
Protein-arginine deiminase type-40303
PPM1D protein2002
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Cytochrome P450 3A40415
Leukotriene A-4 hydrolase0202
Cytochrome P450 2C190213
Histone deacetylase 40101
Histone deacetylase 70101
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20112
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10114
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0112
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
Fumarate hydratase1001
Smad31001
polyprotein1001
bromodomain adjacent to zinc finger domain 2B2002
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
D(1A) dopamine receptor1001
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase PLK12002
eyes absent homolog 2 isoform a1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
muscleblind-like protein 1 isoform 14004
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Muscarinic acetylcholine receptor M20102
Muscarinic acetylcholine receptor M40001
Muscarinic acetylcholine receptor M50001
Phospholipase A2, membrane associated0001
Alpha-1B adrenergic receptor0505
Muscarinic acetylcholine receptor M30001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Thromboxane-A synthase 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 4 subunit alpha0101
C-C chemokine receptor type 20202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0203
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Sodium channel protein type 5 subunit alpha0101
Myosin light chain kinase, smooth muscle0101
Sodium channel protein type 9 subunit alpha0101
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Beta-2 adrenergic receptor0001
Indoleamine 2,3-dioxygenase 20202
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Sodium channel protein type 2 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
Sodium/iodide cotransporter0101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Cytochrome P450 2B60101
Muscarinic acetylcholine receptor M40012
Kappa-type opioid receptor0001
Mu-type opioid receptor0001
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
Ornithine transcarbamylase, mitochondrial0101
2-dehydropantoate 2-reductase0101
Proto-oncogene tyrosine-protein kinase Src0101
Fe(3+)-Zn(2+) purple acid phosphatase0101
Taste receptor type 2 member 310011
Taste receptor type 2 member 600011
Sodium/potassium/calcium exchanger 40112
Taste receptor type 2 member 140011
Taste receptor type 2 member 130011
Taste receptor type 2 member 90011
Taste receptor type 2 member 40011
Sodium/potassium/calcium exchanger 20112
Glutamate 5-kinase0001
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
RGS121001
TPA: protein transporter TIM100101
TPA: protein transporter TIM230101
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 11001
polyadenylate-binding protein 10101
caspase-1 isoform alpha precursor1001
Aurora kinase A0011
Cyclin-G-associated kinase0011
3-phosphoinositide-dependent protein kinase 10011
Death-associated protein kinase 30011
Serine/threonine-protein kinase/endoribonuclease IRE10101
Ribosomal protein S6 kinase alpha-50011
Serine/threonine-protein kinase 160011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Interferon-induced, double-stranded RNA-activated protein kinase0101
Ephrin type-A receptor 30011
Dual specificity protein kinase TTK0112
Mitogen-activated protein kinase 80112
Mitogen-activated protein kinase 90112
Casein kinase I isoform epsilon0011
Dual specificity protein kinase CLK20011
Tyrosine-protein kinase JAK30101
Mitogen-activated protein kinase 120011
Mitogen-activated protein kinase 100112
Caspase-71001
Cyclin-dependent kinase 160011
Serine/threonine-protein kinase 40011
Calcium/calmodulin-dependent protein kinase type 10011
Ribosomal protein S6 kinase alpha-20011
Mitogen-activated protein kinase 140101
AP2-associated protein kinase 10011
Serine/threonine-protein kinase ULK30011
Serine/threonine-protein kinase MARK20011
Calcium/calmodulin-dependent protein kinase type 1D0011
Calcium/calmodulin-dependent protein kinase type 1G0011
Calcium/calmodulin-dependent protein kinase kinase 20011
STE20-like serine/threonine-protein kinase 0011
Dual specificity protein kinase CLK40011
MAP kinase-interacting serine/threonine-protein kinase 20011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase 30011
BMP-2-inducible protein kinase0011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase 17A0011
Death-associated protein kinase 20011
TRAF2 and NCK-interacting protein kinase0011
Aurora kinase C0011
Serine/threonine-protein kinase 38-like0011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Chain A, Bacterial regulatory proteins, tetR family0011
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Prostaglandin G/H synthase 10123
Carbonic anhydrase 30101
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
BRCA11001
P531001
pyruvate kinase1001
M18 aspartyl aminopeptidase0101
cathepsin L10101
lysosomal alpha-glucosidase preproprotein1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
FAD-linked sulfhydryl oxidase ALR0001
Vif0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 10101
transcription factor p65 isoform 10011
serine/threonine-protein kinase 33 isoform a0011
POsterior Segregation0011
Aryl hydrocarbon receptor0101
Estrogen receptor beta0011
Acetylcholinesterase0202
Lysine-specific histone demethylase 1A0101
Transient receptor potential cation channel subfamily A member 10112
Tyrosine-protein kinase ABL10102
Myc proto-oncogene protein0102
Transthyretin0114
Tyrosine-protein kinase Lck0101
Cathepsin D0101
Luciferin 4-monooxygenase0101
DNA polymerase alpha catalytic subunit0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Breakpoint cluster region protein0102
Tyrosinase0202
Ornithine decarboxylase0101
Protein kinase C alpha type0011
Tyrosine-protein phosphatase non-receptor type 10101
Estrogen receptor0011
Nuclear factor NF-kappa-B p105 subunit0101
Endothelin receptor type B1001
Prostaglandin G/H synthase 10101
Sucrase-isomaltase, intestinal0101
Endothelin-1 receptor1001
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10101
Cannabinoid receptor 10202
Alpha-glucosidase MAL120101
Prostaglandin G/H synthase 20101
Cholinesterase0202
Nuclear factor NF-kappa-B p100 subunit 0101
Squalene synthase0101
Transcription factor p650101
Bcl-2-like protein 10101
Serine/threonine-protein kinase PAK 10101
N1L 0101
NAD(P)H dehydrogenase [quinone] 10002
Tubulin beta-2B chain0101
Lysosomal alpha-glucosidase0101
Transient receptor potential cation channel subfamily A member 10101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Carbonic anhydrase 130101
Prenyltransferase homolog0001
Zinc finger protein mex-50011
large T antigen0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Pyruvate kinase PKM0011
Carbonic anhydrase 0202
Gamma-aminobutyric acid receptor subunit rho-30001
Glycine receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit rho-10001
Gamma-aminobutyric acid receptor subunit rho-20001
Glycine receptor subunit beta0101
Taste receptor type 2 member 460011
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0202
Collagenase 30101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
Solute carrier family 22 member 80102
P2Y purinoceptor 120101
Solute carrier family 22 member 110001
Solute carrier family 22 member 70001
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Solute carrier organic anion transporter family member 1A40103
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 1A50002
Rap guanine nucleotide exchange factor 33003
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0246
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
HLA class I histocompatibility antigen, A alpha chain 0011
Chain A, Nuclear Receptor ROR-beta0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Nuclear receptor ROR-beta0101
Thyroid hormone receptor beta0101
Sigma non-opioid intracellular receptor 10011
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 4A10001
Solute carrier organic anion transporter family member 1C10101
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
Solute carrier family 22 member 60001
Solute carrier family 2, facilitated glucose transporter member 90112
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]