Page last updated: 2024-08-05 11:57:17

flavonols

Any hydroxyflavone in which is the ring hydrogen at position 3 of the heterocyclic ring is replaced by a hydroxy group.

ChEBI ID: 28802

Members (15)

MemberDefinitionRole
3-hydroxyflavoneA monohydroxyflavone that is the 3-hydroxy derivative of flavone.flavonol
eupatinA trimethoxyflavone that is quercetagetin methylated at positions 4', 6 and 7.eupatin
icariinA member of the class of flavonols that is kaempferol which is substituted at position 8 by a 3-methylbut-2-en-1-yl group and in which the hydroxy groups at positions 3, 4', and 7 have been converted to the corresponding 6-deoxy-alpha-L-mannopyranoside, methyl ether, and beta-D-glucopyranoside, respectively. A phoshphodiesterase-5 inhibitor, it is obtained from several species of plants in the genus Epimedium and is thought to be the main active ingredient of the Chinese herbal medicine Herba Epimedii (yinyanghuo).icariin
kaempferolA tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment.kaempferol
kaempferol 3-O-beta-L-glucopyranosideA kaempferol O-glucoside that is kaempferol attached to a beta-L-glucopyranosyl moiety at position 3 via a glycosidic linkage.kaempferol 3-O-beta-L-glucopyranoside
kaempferol 7-o-glucosideA kaempferol O-glucoside that is kaempferol attached to a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.kaempferol 7-O-beta-D-glucopyranoside
kaempferol-7-methyl etherA monomethoxyflavone that is the 7-methyl ether derivative of kaempferol.rhamnocitrin
ombuineA dimethoxyflavone that is quercetin in which the hydroxy groups at positions 7 and 4' are replaced by methoxy groups. Isolated from Cyperus teneriffae, it exhibits anti-inflammatory activity.ombuin
papyriflavonol aA pentahydroxyflavone that is flavone substituted with hydroxy groups at positions 3, 5, 7, 3' and 4' and prenyl groups at positions 6 and 5'. Isolated from Broussonetia papyrifera, it exhibits inhibitory activity against phospholipase A2 and tyrosinase.papyriflavonol A
patuletinA trimethoxyflavone that is quercetagetin methylated at position 6.patuletin
quercetagetinA hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 5, 6, 7, 3' and 4' respectively.quercetagetin
quercetin 5,7,3',4'-tetramethyl etherA tetramethoxyflavone that is the 5,7,3',4'-tetramethy-derivative of quercetin.quercetin 5,7,3',4'-tetramethyl ether
quercetin 7-rhamnosideA quercetin O-glycoside that is quercetin attached to a alpha-L-rhamnopyranosyl moiety at position 7 via a glycosidic linkage.quercetin 7-O-alpha-L-rhamnopyranoside
quercimeritrinA quercetin O-glucoside in which a glucosyl residue is attached at position 7 of quercetin via a beta-glycosidic linkage.quercetin 7-O-beta-D-glucoside
spiraeosideA quercetin O-glucoside that is quercetin with a beta-D-glucosyl residue attached at position 4'.quercetin 4'-O-beta-D-glucopyranoside

Research

Studies (5,771)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990106 (1.84)18.7374
1990's273 (4.73)18.2507
2000's1,367 (23.69)29.6817
2010's2,973 (51.52)24.3611
2020's1,052 (18.23)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials101 (1.62%)5.53%
Reviews296 (4.76%)6.00%
Case Studies2 (0.03%)4.05%
Observational4 (0.06%)0.25%
Other5,819 (93.52%)84.16%