Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
| Member | Definition | Class |
|---|
| azaperone | An N-arylpiperazine that is 2-(piperazin-1-yl)pyridine in which the amino hydrogen is replaced by a 3-(4-fluobenzoyl)propyl group. Used mainly as a tranquiliser for pigs and elephants. | azaperone |
| benzquinamide | | benzquinamide |
| chlormezanone | A 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions. | chlormezanone |
| dapiprazole | | dapiprazole |
| etazolate | A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties. | etazolate |
| levosulpiride | An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, D1 and D5 receptors respectively). | (S)-(-)-sulpiride |
| loxapine | | loxapine |
| ly 379268 | An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia. | LY 379268 |
| ly 404039 | An organic heterobicyclic compound that is (1S,5R)-2-thiabicyclo[3.1.0]hexane carrying oxo, oxo, amino, carboxy, and carboxy groups at positions 2, 2, 4S, 4S, and 6S, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 mGluR3 (Ki = 149 nM and 92 nM, respectively) and exhibits antipsychotic and anxiolytic efficacy in animal models. | LY404039 |
| methiothepin | A dibenzothiepine that is 10,11-dihydrodibenzo[b,f]thiepine bearing additional methylthio and 4-methylpiperazin-1-yl substituents at positions 8 and 10 respectively. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays affinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively). | methiothepin |
| n,n-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride | An aromatic ether that is (2-phenoxyethyl)benzene which carries a 2-(dipropylamino)ethyl group at position 3 and a methoxy group at position 6. It is a potent and selective sigma1 receptor antagonist. | N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine hydrochloride |
| pimavanserin | A member of the class of ureas in which three of the four hydrogens are replaced by 4-fluorobenzyl, 1-methylpiperidin-4-yl, and 4-(isopropyloxy)benzyl groups. An atypical antipsychotic that is used (in the form of its tartrate salt) for treatment of hallucinations and delusions associated with Parkinson's disease. | pimavanserin |
| ritanserin | A thiazolopyrimidine that is 5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one which is substituted at position 7 by a methyl group and at position 6 by a 2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl group. A potent and long-acting seratonin (5-hydroxytryptamine, 5-HT) antagonist of the subtype 5-HT2 (Ki = 0.39 nM), it is used in the treatment of a variety of disorders including anxiety, depression and schizophrenia. It has little sedative action. | ritanserin |
| spiperone | An azaspiro compound that is 1,3,8-triazaspiro[4.5]decane which is substituted at positions 1, 4, and 8 by phenyl, oxo, and 4-(p-fluorophenyl)-4-oxobutyl groups, respectively. | spiperone |
| sulpiride | A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine. | sulpiride |
| ziprasidone | A piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms. | ziprasidone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 33.9972 | 1 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 29.3671 | 3 | 10 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 14.3185 | 2 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 17.9008 | 1 | 2 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 21.7986 | 10 | 31 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 47.3026 | 2 | 4 |
| arylsulfatase A | Homo sapiens (human) | Potency | 16.2743 | 1 | 6 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 17.0363 | 3 | 6 |
| Ataxin-2 | Homo sapiens (human) | Potency | 22.9986 | 2 | 5 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 11.9986 | 1 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 28.8993 | 2 | 3 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 23.9341 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 21.3016 | 1 | 2 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 5.9283 | 2 | 6 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 42.8000 | 1 | 2 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 33.4915 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 22.9342 | 1 | 5 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 13.9115 | 2 | 4 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 14.3295 | 2 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 40.0748 | 2 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 32.6448 | 2 | 5 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 28.1730 | 2 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 32.6448 | 2 | 5 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 33.4036 | 1 | 4 |
| CREB-binding protein | Homo sapiens (human) | Potency | 5.4415 | 3 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 12.0019 | 1 | 4 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 23.1103 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 25.1918 | 1 | 5 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 5.7604 | 1 | 6 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 8.0265 | 1 | 6 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 13.9667 | 2 | 12 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 19.0761 | 2 | 10 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 25.5098 | 1 | 5 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 3.7150 | 3 | 11 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 18.4927 | 1 | 1 |
| D(3) dopamine receptor isoform e | Homo sapiens (human) | Potency | 0.0891 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 21.1923 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 28.2580 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 29.9349 | 1 | 1 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 0.0580 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.8641 | 8 | 28 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 16.6529 | 2 | 5 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 21.5650 | 9 | 24 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 27.3723 | 1 | 11 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 20.9587 | 4 | 13 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 23.8751 | 2 | 4 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 31.4030 | 1 | 5 |
| G | Vesicular stomatitis virus | Potency | 25.1918 | 1 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 13.9667 | 1 | 6 |
| geminin | Homo sapiens (human) | Potency | 10.8425 | 3 | 11 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 14.2013 | 2 | 8 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 19.0919 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 12.6986 | 2 | 4 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 25.4348 | 3 | 12 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 17.5080 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 16.0341 | 2 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 33.4889 | 2 | 2 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 18.0750 | 2 | 17 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 29.0144 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 52.1952 | 2 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 25.1918 | 1 | 5 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 17.2966 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 12.6658 | 2 | 8 |
| IDH1 | Homo sapiens (human) | Potency | 23.1093 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 25.1918 | 1 | 10 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 3.5481 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 18.3174 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 18.3174 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 27.2193 | 2 | 6 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 16.8240 | 2 | 8 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 14.0260 | 1 | 3 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 30.5687 | 1 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 18.7484 | 2 | 7 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 13.6235 | 2 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 8.1005 | 2 | 5 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.2269 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 5.0119 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 19.3218 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 80.0783 | 1 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 12.0634 | 2 | 6 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 25.8598 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 25.1334 | 2 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 14.9893 | 2 | 6 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 0.0063 | 1 | 2 |
| Parkin | Homo sapiens (human) | Potency | 25.9290 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 32.8970 | 1 | 2 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 64.6340 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 18.1488 | 3 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 26.2788 | 2 | 5 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 45.2852 | 1 | 3 |
| polyprotein | Zika virus | Potency | 31.4030 | 1 | 5 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 12.4103 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 7.4479 | 1 | 7 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 9.7262 | 2 | 5 |
| progesterone receptor | Homo sapiens (human) | Potency | 26.5920 | 3 | 6 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 0.0063 | 2 | 3 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 22.3826 | 2 | 8 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 63.6286 | 1 | 4 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 25.2127 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 22.9861 | 3 | 7 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 17.1899 | 2 | 9 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 17.8929 | 4 | 5 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 27.0105 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 27.0105 | 2 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 14.3335 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 28.4661 | 1 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 17.8144 | 2 | 15 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 31.6228 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 5.0374 | 2 | 7 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 18.3058 | 2 | 10 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 81.1603 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 21.9596 | 5 | 11 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 9.9878 | 2 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 45.9115 | 2 | 6 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 14.2699 | 2 | 6 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 23.9460 | 3 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 56.0846 | 1 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 17.5080 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | Ki | 0.0130 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 4.2600 | 2 | 2 |
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | Ki | 0.0495 | 13 | 15 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 0.3576 | 7 | 7 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 2.0600 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 2.0457 | 3 | 3 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Ki | 0.1600 | 1 | 1 |
| 5-hydroxytryptamine receptor 1E | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Ki | 0.1600 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 0.0741 | 7 | 11 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 0.1258 | 7 | 8 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 0.0170 | 19 | 24 |
| 5-hydroxytryptamine receptor 2A | Mus musculus (house mouse) | Ki | 0.0008 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 1.9320 | 13 | 14 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 0.1927 | 2 | 6 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 0.1677 | 6 | 6 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.3368 | 2 | 2 |
| 5-hydroxytryptamine receptor 2B | Mus musculus (house mouse) | Ki | 0.0008 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 3.3758 | 7 | 8 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 0.1209 | 2 | 6 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.2866 | 7 | 7 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 0.3316 | 17 | 22 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 2.9606 | 9 | 10 |
| 5-hydroxytryptamine receptor 2C | Mus musculus (house mouse) | Ki | 0.0008 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | Ki | 0.3981 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | Ki | 0.3981 | 1 | 1 |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | Ki | 0.3981 | 1 | 1 |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | Ki | 0.3981 | 1 | 1 |
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | Ki | 0.3981 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 0.6250 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 0.3270 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 35.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | Ki | 12.6267 | 4 | 5 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 0.0300 | 5 | 5 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 0.1868 | 17 | 19 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Ki | 0.0679 | 3 | 3 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 0.0075 | 5 | 5 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | Ki | 0.1672 | 18 | 24 |
| 5-hydroxytryptamine receptor 7 | Mus musculus (house mouse) | Ki | 0.0630 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Ki | 0.0182 | 3 | 7 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.8427 | 6 | 6 |
| Alpha-1A adrenergic receptor | Bos taurus (cattle) | Ki | 0.0135 | 1 | 1 |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | Ki | 0.0090 | 4 | 4 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.5138 | 8 | 10 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.7405 | 4 | 4 |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | Ki | 0.0086 | 5 | 5 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 2.1604 | 6 | 7 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 0.0097 | 2 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.7405 | 4 | 4 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 0.0080 | 5 | 5 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.8931 | 7 | 8 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 2.0190 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1514 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.5123 | 3 | 3 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0072 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 1.1530 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1514 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.4353 | 3 | 3 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0072 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.1514 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.3900 | 2 | 2 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.0072 | 1 | 1 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | Ki | 0.0022 | 1 | 2 |
| Aspartate aminotransferase, cytoplasmic | Homo sapiens (human) | IC50 | 5.3900 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 2.3000 | 1 | 1 |
| Beta-casein | Rattus norvegicus (Norway rat) | Ki | 0.0015 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 354.8000 | 3 | 4 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Calcitonin gene-related peptide type 1 receptor | Homo sapiens (human) | Ki | 0.0520 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 0.7600 | 2 | 2 |
| Carbonic anhydrase | Helicobacter pylori 26695 | Ki | 0.1915 | 2 | 2 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ki | 0.1240 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 0.4150 | 1 | 1 |
| Carbonic anhydrase | Anopheles gambiae (African malaria mosquito) | Ki | 0.0295 | 1 | 1 |
| Carbonic anhydrase | Astrosclera willeyana | Ki | 0.3780 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Ki | 0.8120 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ki | 0.1130 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 0.4300 | 2 | 2 |
| Carbonic anhydrase | Sulfurihydrogenibium sp. YO3AOP1 | Ki | 0.0674 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 4.2183 | 33 | 35 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 0.0039 | 3 | 3 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 0.0730 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 0.0400 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 0.3170 | 40 | 43 |
| Carbonic anhydrase 2 | Mycobacterium tuberculosis H37Rv | Ki | 0.2660 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 10.6000 | 1 | 1 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | IC50 | 0.6200 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 0.1740 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 0.0180 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 2.0072 | 4 | 6 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 2.4212 | 3 | 3 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 0.0409 | 6 | 7 |
| Carbonic anhydrase, alpha family | Hydrogenovibrio crunogenus XCL-2 | Ki | 0.8730 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase A | Homo sapiens (human) | Ki | 12.0000 | 1 | 1 |
| cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Homo sapiens (human) | Ki | 12.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 52.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 49.8000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 75.0000 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.0610 | 1 | 2 |
| D | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D | Rattus norvegicus (Norway rat) | IC50 | 0.5757 | 2 | 2 |
| D | Bos taurus (cattle) | Ki | 50.0000 | 2 | 2 |
| D | Rattus norvegicus (Norway rat) | Ki | 1.1510 | 4 | 4 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 0.0942 | 4 | 5 |
| D(1B) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.8010 | 2 | 2 |
| D(2) dopamine receptor | Canis lupus familiaris (dog) | IC50 | 0.2000 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 1.0446 | 9 | 10 |
| D(2) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | IC50 | 0.2108 | 14 | 16 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 0.0413 | 34 | 40 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.0797 | 17 | 28 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 0.1413 | 7 | 8 |
| D(3) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.0319 | 21 | 26 |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.8010 | 2 | 2 |
| D(4) dopamine receptor | Homo sapiens (human) | IC50 | 0.0072 | 2 | 2 |
| D(4) dopamine receptor | Mus musculus (house mouse) | IC50 | 35.0000 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 0.3425 | 16 | 19 |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.8010 | 2 | 2 |
| Delta carbonic anhydrase | Conticribra weissflogii | Ki | 0.2590 | 1 | 1 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.6200 | 2 | 2 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0400 | 1 | 1 |
| Diacylglycerol kinase alpha | Homo sapiens (human) | IC50 | 12.8500 | 2 | 2 |
| Endothelin receptor type B | Homo sapiens (human) | Ki | 0.0179 | 2 | 4 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Ki | 0.0179 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Ki | 49.6000 | 1 | 1 |
| Glycogen phosphorylase, muscle form | Homo sapiens (human) | Ki | 49.6000 | 1 | 1 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0970 | 1 | 1 |
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 2 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0060 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 0.1531 | 4 | 4 |
| Histamine H4 receptor | Homo sapiens (human) | Ki | 4.2759 | 2 | 2 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | Ki | 0.3694 | 3 | 6 |
| Metabotropic glutamate receptor 3 | Homo sapiens (human) | Ki | 0.1937 | 3 | 6 |
| Metabotropic glutamate receptor 4 | Homo sapiens (human) | Ki | 21.0000 | 1 | 1 |
| Metabotropic glutamate receptor 5 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | Ki | 0.4000 | 1 | 1 |
| Metabotropic glutamate receptor 7 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | Ki | 1.7000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0400 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 1.2000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 17.4250 | 4 | 4 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Ki | 49.6000 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 27.3000 | 2 | 2 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | Ki | 49.6000 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 27.3000 | 2 | 2 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | Ki | 49.6000 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 27.3000 | 2 | 2 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | Ki | 49.6000 | 1 | 1 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | Ki | 27.3000 | 2 | 2 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | Ki | 49.6000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 7.6800 | 1 | 1 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 0.2481 | 9 | 10 |
| Sigma intracellular receptor 2 | Homo sapiens (human) | Ki | 0.0511 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 0.9550 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 0.4052 | 1 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.1514 | 1 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 0.2941 | 4 | 6 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.0031 | 2 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.0662 | 2 | 2 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.0210 | 1 | 1 |
| sphingosine 1-phosphate receptor 3 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 0.0480 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Vesicular acetylcholine transporter | Rattus norvegicus (Norway rat) | Ki | 1.0330 | 1 | 1 |