tetracycline and Puerperal-Disorders

The investigations were carried out on a total of 70 cows with puerperal endometritis. In addition to intrauterine antibiotic treatment, 30 experimental animals were administered 20 microg GnRH analogue, buserelin, between days 10 and 12 post-partum followed by 500 microg PGF2alpha analogue, cloprostenol, 10 days later. Forty control cows were treated only with intrauterine antibiotics. Blood samples for progesterone determination were collected from the tail vein twice weekly until day 70 post-partum. The first rise in progesterone level above 3.18 nmol/l occurred significantly earlier in the experimental than in control cows (21.6 +/- 9.2 versus 27.8 +/- 12.3 days; p < or = 0.05). The duration of the first cycle post-partum was 15.0 +/- 4.3 days in experimental and 19.7 +/- 7.3 days in control animals (p < or = 0.05). However, no significant differences were observed in the occurrence of first oestrus post-partum. The involution of the uterus was improved after hormone treatment. At day 42 post-partum, completion of uterine involution was found in 93.3% of hormone-treated cows and in 82.5% of those treated with antibiotic only (p < or = 0.05). Clinical recovery was 96.6% in the experimental and 82.5% in the control group (p < or = 0.05). First service pregnancy rate was significantly better in hormone-treated than control cows (51.7 versus 36.4%; p < or = 0.05). Total pregnancy rate and insemination index values were not significantly improved following GnRH and PGF2alpha treatment. The average service period was 89.8 +/- 21.2 days in cows after hormone treatment, and 112.6 +/- 24.5 days in control cows. The difference was statistically significant (p < or = 0.05). These results indicate, that the sequential GnRH and PGF2alpha application in cows with puerperal endometritis positively affected ovarian function and uterine involution, resulting in improved fertility performance.

Topics: Animals; Buserelin; Cattle; Cattle Diseases; Cloprostenol; Dairying; Dinoprost; Drug Administration Schedule; Drug Therapy, Combination; Endometritis; Erythromycin; Female; Fertility; Fertility Agents, Female; Progesterone; Puerperal Disorders; Tetracycline

In 11 specialised dairy farms belonging to the herd book and cattle health service of the Bureau of animal health in Hannover 1134 gynaecological examinations had been accomplished during a two and a half years period every four weeks. 120 cows (approximately 10%) showed an ichorous vaginal secretion between the second and third week post partum. The treatment was conducted beginning from ten days post partum with a high antibiotical dosage (4 g Tetracycline) in shape of small-sized pessaries (UT-forte, MSD) and additionally the cows received 20 micrograms GnRH (Receptal, Hoechst) by intramuscular injection. 3-4 weeks later the cows were reexamined, 36 cows did not reveal any abnormal signs, the remainder had to be treated in accordance with the diagnosis in the sexual tract (on average 1.16 times). After a mean interval calving to first service of 93 days 85% of the cows with lochiometra needed some more than two A. l's with a six weeks' delay to get pregnant. The reasons for the differences between the results of this study and those of other investigations are explained. It requires a great deal of veterinary labor to prevent the inflammatory processes in the genital tract from getting chronic, that is why lochiometra must be looked upon as one of the most aggravating puerperal disease. The medical care of the uterus with high doses of antibiotics combined with the application of GnRH must be recognized as a good supplement to the therapy of retained placenta favoured by Götze or other puerperal disorders such as lochiometra especially in regard to compatibility and high pregnancy rates.(ABSTRACT TRUNCATED AT 250 WORDS)

Topics: Animals; Cattle; Cattle Diseases; Drug Therapy, Combination; Female; Gonadotropin-Releasing Hormone; Puerperal Disorders; Tetracycline; Uterine Diseases

Topics: Animals; Drug Therapy, Combination; Female; Oxytocics; Pregnancy; Puerperal Disorders; Swine; Swine Diseases; Tetracycline

Topics: Acne Vulgaris; Adrenal Cortex Hormones; Adrenal Glands; Adult; Androgens; Dexamethasone; Estrogens; Female; Humans; Menstruation; Metabolic Diseases; Pregnancy; Puerperal Disorders; Tetracycline

Topics: Adolescent; Adult; Aged; Anemia, Macrocytic; Female; Folic Acid; Humans; Jejunum; Malabsorption Syndromes; Male; Middle Aged; Pregnancy; Puerperal Disorders; Radiography; South Africa; Sprue, Tropical; Tetracycline

Topics: Adolescent; Adult; Cyclohexanes; Endometritis; Female; Humans; Pregnancy; Puerperal Disorders; Puerperal Infection; Sulfuric Acids; Tetracycline; Urinary Tract Infections

Topics: Abortion, Septic; Adult; Anti-Inflammatory Agents; Female; Genital Diseases, Female; Humans; Middle Aged; Pregnancy; Puerperal Disorders; Tetracycline

Topics: Anti-Bacterial Agents; Biomedical Research; Female; Humans; Penicillin G; Penicillins; Pharmacology; Puerperal Disorders; Tetracycline

Topics: Communicable Diseases; Cross Infection; Drug Resistance; Drug Resistance, Microbial; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Israel; Mastitis; Mothers; Penicillins; Pregnancy; Pregnancy Complications, Infectious; Puerperal Disorders; Pyoderma; Staphylococcal Infections; Staphylococcus aureus; Streptomycin; Sulfathiazoles; Tetracycline

Topics: Anti-Bacterial Agents; Chloramphenicol; Female; Humans; Postpartum Period; Pregnancy; Puerperal Disorders; Puerperal Infection; Syndrome; Tetracycline