Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6.
| Member | Definition | Role |
|---|
| amdinocillin | A penicillin in which the 6beta substituent is [(azepan-1-yl)methylidene]amino; an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. | mecillinam |
| amdinocillin pivoxil | A penicillanic acid ester that is the [(2,2-dimethylpropanoyl)oxy]methyl ester and prodrug of mecillinam. | pivmecillinam |
| amoxicillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group. | amoxicillin |
| ampicillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group. | ampicillin |
| apalcillin | | apalcillin |
| azidocillin | | azidocillin |
| azlocillin | A semisynthetic penicillin having a 6beta-{(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl}amino side-group. It is an antibiotic used in treating infections caused by Pseudomonas aeruginosa, Escherichia coli and Haemophilus influenzae. | azlocillin |
| carbenicillin | A penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain. | carbenicillin |
| carbenicillin indanyl | | carindacillin |
| carfecillin | | carfecillin |
| cloxacillin | A semisynthetic penicillin antibiotic carrying a 3-(2-chlorophenyl)-5-methylisoxazole-4-carboxamido group at position 6. | cloxacillin |
| cyclacillin | | cyclacillin |
| dicloxacillin | A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group. | dicloxacillin |
| epicillin | A penicillin in which the substituent at position 6 of the penam ring is a (2R)-2-amino-2-(cyclohexa-1,4-dien-1-yl)acetamido group. | epicillin |
| floxacillin | A penicillin compound having a 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido] side-chain. | flucloxacillin |
| hetacillin | | hetacillin |
| methampicillin | A penicillin compound having a 6beta-(2R)-2-(methylideneamino)-2-phenylacetamido side-group. | metampicillin |
| methicillin | A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group. | methicillin |
| mezlocillin | A penicillin in which the substituent at position 6 of the penam ring is a (2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido group. | mezlocillin |
| nafcillin | A penicillin in which the substituent at position 6 of the penam ring is a (2-ethoxy-1-naphthoyl)amino group. | nafcillin |
| oxacillin | A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta. | oxacillin |
| penicillin f | | Penicillin F |
| penicillin g | A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. | benzylpenicillin |
| penicillin k | | Penicillin K |
| penicillin n | | penicillin N |
| penicillin v | | 3,3-dimethyl-7-oxo-6-[(1-oxo-2-phenoxyethyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| penicillin v | A penicillin compound having a 6beta-(phenoxyacetyl)amino side-chain. | phenoxymethylpenicillin |
| penicillin x | | Penicillin X |
| phenethicillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-phenoxypropanamido group. | phenethicillin |
| piperacillin | A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group. | piperacillin |
| propicillin | | propicillin |
| quinacillin | A semisynthetic penicillase-resistant penicillin with antibacterial activity; it binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. | quinacillin |
| sulbenicillin | A penicillin antibiotic having a 6beta-[phenyl(sulfo)acetamido] side-chain. | sulbenicillin |
| temocillin | A penicillin compound having a 6alpha-methoxy and 6beta-[2-carboxy(thiophen-3-yl)acetamido side-groups. | temocillin |
| ticarcillin | A penicillin compound having a 6beta-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group. | ticarcillin |
| Tobicillin | | Tobicillin |