Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
Member | Definition | Class |
4-aminopyridine | An aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis. | 4-aminopyridine |
4-phenylbutyric acid, sodium salt | The organic sodium salt of 4-phenylbutyric acid. A prodrug for phenylacetate, it is used to treat urea cycle disorders. | sodium phenylbutyrate |
carglumic acid | A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. | carglumic acid |
isavuconazole | A 1,3-thiazole that is butan-2-ol which is substituted at positions 1, 2, and 3 by 1,2,4-triazol-1-yl, 2,5-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively. It is an antifungal drug used for the treatment of invasive aspergillosis and invasive mucormycosis. | isavuconazole |
ixazomib | A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixazomib citrate, it is used in combination therapy for treatment of multiple myeloma. | ixazomib |
lenvatinib | A member of the class of quinolines that is the carboxamide of 4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxylic acid. A multi-kinase inhibitor and orphan drug used (as its mesylate salt) for the treatment of various types of thyroid cancer that do not respond to radioiodine. | lenvatinib |
lumacaftor | An aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis. | lumacaftor |
macitentan | A member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension. | macitentan |
mre 269 | A member of the class of pyrazines that is {4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetic acid carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. The active metabolite of selexipag, an orphan drug used for the treatment of pulmonary arterial hypertension. | ACT-333679 |
pn 401 | An acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity. | uridine triacetate |
rifaximin | A semisynthetic member of the class of rifamycins and non-systemic gastrointestinal site-specific broad spectrum antibiotic. Used in the treatment of traveller's diarrhoea, hepatic encephalopathy and irritable bowel syndrome. | rifaximin |
selexipag | A member of the class of pyrazines that is N-(methanesulfonyl)-2-{4-[(propan-2-yl)(pyrazin-2-yl)amino]butoxy}acetamide carrying two additional phenyl substituents at positions 5 and 6 on the pyrazine ring. An orphan drug used for the treatment of pulmonary arterial hypertension. It is a prodrug for ACT-333679 (the free carboxylic acid). | selexipag |
vx-770 | An aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis. | ivacaftor |
Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Activin receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Activin receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Activin receptor type-2B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
ATP-dependent Clp protease proteolytic subunit | Staphylococcus aureus subsp. aureus NCTC 8325 | EC50 | 3.6000 | 1 | 1 |
ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Aurora kinase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Aurora kinase B | Homo sapiens (human) | Kd | 1.7810 | 1 | 1 |
Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Breakpoint cluster region protein | Homo sapiens (human) | Kd | 4.1130 | 1 | 1 |
Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Casein kinase I isoform delta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | EC50 | 0.7447 | 17 | 17 |
Cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | Kd | 60.3000 | 2 | 2 |
Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 0.2180 | 1 | 1 |
DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 2.9100 | 1 | 1 |
Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Epidermal growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 0.0460 | 1 | 1 |
Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 2.9530 | 2 | 2 |
Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Guanine nucleotide-binding protein G(i) subunit alpha-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Insulin receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
LIM domain kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
LIM domain kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 0.0630 | 1 | 1 |
MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 0.2170 | 1 | 1 |
Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 1.5750 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 0.5780 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 3.1170 | 1 | 1 |
Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 9.1200 | 5 | 5 |
Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 0.3160 | 1 | 1 |
Potassium channel subfamily K member 2 | Homo sapiens (human) | EC50 | 2,750.0000 | 1 | 1 |
Potassium voltage-gated channel subfamily A member 3 | Homo sapiens (human) | Kd | 195.0000 | 1 | 1 |
Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Prostacyclin receptor | Homo sapiens (human) | EC50 | 0.0140 | 1 | 2 |
Prostacyclin receptor | Rattus norvegicus (Norway rat) | EC50 | 0.2000 | 1 | 1 |
Prostaglandin D2 receptor | Homo sapiens (human) | EC50 | 0.1270 | 1 | 2 |
Protein kinase C alpha type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Protein kinase C delta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Protein kinase C iota type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Protein kinase C theta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 0.1730 | 1 | 1 |
Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 0.0090 | 1 | 1 |
Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 0.0110 | 1 | 1 |
Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 0.3160 | 1 | 1 |
Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 1.5230 | 1 | 1 |
RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 0.7930 | 1 | 1 |
Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 2.2420 | 1 | 1 |
Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 3.8510 | 1 | 1 |
STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 0.5650 | 1 | 1 |
Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 3.7710 | 1 | 1 |
Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 0.0021 | 1 | 1 |
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
Wee1-like protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |