Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
| Member | Definition | Role |
|---|
| (1S,3aR,4S,6S,6aS,9aS,9bS)-9a-isocyano-6-(2-isocyano-2-methylpropyl)-1,4-dimethyl-7-methylidene-2,3,3a,4,5,6,6a,8,9,9b-decahydro-1H-phenalene | | (1S,3aR,4S,6S,6aS,9aS,9bS)-9a-isocyano-6-(2-isocyano-2-methylpropyl)-1,4-dimethyl-7-methylidene-2,3,3a,4,5,6,6a,8,9,9b-decahydro-1H-phenalene |
| 1-(3-hydroxy-3-methylpent-4-en-1-yl)-2,5,5,8a-tetramethyl-decahydronaphthalen-2-ol | | 1-(3-hydroxy-3-methylpent-4-en-1-yl)-2,5,5,8a-tetramethyl-decahydronaphthalen-2-ol |
| alloxanthin | | Alloxanthin/Tetradehydrozeaxanthin/(Cynthiaxanthin)/(Pectenoxanthin) |
| bielschowskysin | A diterpenoid that is isolated from Pseudopterogorgia kallos and exhibits antimalarial and anticancer activity. | bielschowskysin |
| brasilicardin a | A diterpenoid antibiotic isolated from the culture broth of Nocardia brasiliensis IFM0406. It exhibits antitumour and strong immunosuppressive activity. | brasilicardin A |
| bromophycolide a | A diterpenoid that is a macrolide isolated from the Fijian red alga Callophycus serratus. It has been found to exhibit moderate cytotoxicity against several human tumour cell lines via specific apotopic cell death. It also displays anti-HIV, antibacterial, antifungal and antimalarial activity. | bromophycolide A |
| cafestol | An organic heteropentacyclic compound and furan diterpenoid with formula C20H28O3 obtained from the unsaponifiable fraction of coffee oil (a lipid fraction obtained from coffee beans by organic solvent extraction). | cafestol |
| callystatin a | | Callystatin A |
| cannabigerolic acid | A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant. | cannabigerolic acid |
| carnosol | | Carnosol |
| copalic acid | | Copalic acid |
| cyclooctatin | A diterpenoid characterized by a 5-8-5 dodecahydrodicyclopenta[a,d]cyclooctene fused-ring system, with a single double bond and one isopropyl, two hydroxy, one hydroxymethyl and two methyl substituents. | cyclooctatin |
| cyrneine a | | Cyrneine A |
| dehydroabietylamine | | [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine |
| Delcorine | | Delcorine |
| Delsoline | | Delsoline |
| delta(9)-tetrahydrocannabinolic acid | A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant. | Delta(9)-tetrahydrocannabinolic acid |
| diacetyl benzoyl lathyrol | | diacetyl benzoyl lathyrol |
| discodermolide | | Discodermolide |
| Diterpene deriv 329 | | Diterpene deriv 329 |
| dronabinol | A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. The principal psychoactive constituent of the cannabis plant, it is used for treatment of anorexia associated with AIDS as well as nausea and vomiting associated with cancer chemotherapy. | Delta(9)-tetrahydrocannabinol |
| ebc-46 | A diterpenoid natural product isolated from the kernels of the Australian blushwood tree (Fontainea picrosperma). It is approved as a veterinary pharmaceutical for the treatment of non-metastatic and non-resectable canine mast cell tumours. | tigilanol tiglate |
| ecabet | | ecabet |
| erinacine a | | Erinacine A |
| Erinacine C | | Erinacine C |
| gardenia yellow | A diester that is crocetin in which both of the carboxy groups have been converted to their gentiobiosyl esters. It is one of the water-soluble yellow-red pigments of saffron and is used as a spice for flavouring and colouring food. Note that in India, the term 'Crocin' is also used by GlaxoSmithKline as a brand-name for paracetamol. | crocin-1 |
| geranylgeranic acid | A diterpenoid obtained by formal oxidation of the CH2OH group of (E,E,E)-geranylgeraniol to the corresponding carboxylic acid. | (2E,6E,10E)-geranylgeranic acid |
| isopimaric acid | | isopimaric acid |
| isorenieratene | | Isorenieratene |
| isosteviol | | Isosteviol |
| jatrophatrione | | Jatrophatrione |
| kahweol | A diterpenoid with formula C20H26O3, isolated from the beans of Coffea arabica. It exhibits antioxidant, anti-inflammatory, anti-angiogenesis and anti-proliferative properties. | kahweol |
| kirenol | | Kirenol |
| lycoctonine | | Lycoctonine |
| mezerein | | Mezerein |
| n-acetyl-s-geranylgeranyl-cysteine | | N-acetyl-s-geranylgeranyl-l-cysteine |
| norbixin | | Norbixin |
| phytenic acid | | 2E-Phytenoic acid |
| pimaric acid | | (+)-Pimaric acid |
| plaunotol | A diterpenoid that is geranylgeraniol carrying an additional hydroxy substituent at position 18. | plaunotol |
| Pseudopterosin G-J aglycone | | Pseudopterosin G-J aglycone |
| rediocide a | A diterpenoid of the class of daphnane-type terpenes. It is isolated from Trigonostemon reidioides and has been shown to exhibit insecticidal activity. | rediocide A |
| resiniferatoxin | A heteropentacyclic compound found in Euphorbia poissonii with molecular formula C37H40O9. It is an agonist of the transient receptor potential cation channel subfamily V member 1 (TrpV1). | resiniferatoxin |
| salvileucalin b | A diterpenoid with a rearranged neo-clerodane skeleton isolated from Salvia leucantha and has been shown exhibit antineoplastic activity. | salvileucalin B |
| suberosanone | | Suberosanone |
| suillin | | Suillin |
| taxodione | | Taxodione |
| terpentecin | | terpentecin |
| tocotrienols | | (R)-3,4-Dihydro-2-methyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol |
| totarol | | totarol |
| trans-phytol | A diterpenoid that is hexadec-2-en-1-ol substituted by methyl groups at positions 3, 7, 11 and 15. | phytol |
| triptolide | | Triptolide |
| tuberculosinol | | tuberculosinol |
| yuanhuadine | | Yuanhuadine |