A compound that inhibits the growth of marine organisms.
ChEBI ID: 51076
| Member | Definition | Class |
|---|---|---|
| 2-methyl-4-isothiazolin-3-one | A 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom. It is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM). | methylisothiazolinone |
| 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1h-pyrrole-3-carbonitrile | A pyrrole resulting from the N-dealkylation of the ethoxymethyl group of chlorfenapyr. It is the active insecticide of the proinsecticide chlorfenapyr. | tralopyril |
| chloramine-t | An organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen. | chloramine T |
| irgarol 1051 | A diamino-1,3,5-triazine that is 1,3,5-triazine-2,4-diamine carrying a N-tert-butyl, N'-cyclopropyl and a methylsulfanyl group at position 6. | irgarol 1051 |
| zosteric acid | An aryl sulfate that is (2E)-3-phenylprop-2-enoic acid which is substituted by a sulfooxy group at position 4. It is produced by the seagrass Zostera marina and has very promising antifouling potential against several micro- and macrofouling organisms. | 4-(sulfooxy)-cinnamic acid |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 177 (18.17) | 18.7374 |
| 1990's | 166 (17.04) | 18.2507 |
| 2000's | 206 (21.15) | 29.6817 |
| 2010's | 337 (34.60) | 24.3611 |
| 2020's | 88 (9.03) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 14 (1.32%) | 5.53% |
| Reviews | 34 (3.21%) | 6.00% |
| Case Studies | 140 (13.22%) | 4.05% |
| Observational | 3 (0.28%) | 0.25% |
| Other | 868 (81.96%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 41.9968 | 3 | 4 |
| AR protein | Homo sapiens (human) | Potency | 36.9394 | 4 | 8 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 1.1042 | 2 | 2 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 33.3536 | 5 | 8 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 43.4488 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 30.3740 | 6 | 16 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 2.5551 | 2 | 6 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 2.1872 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 45.9302 | 1 | 3 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 43.0930 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 126.7930 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 54.9410 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 58.8080 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 58.5736 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 12.3097 | 3 | 8 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 28.3298 | 1 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 32.9932 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 18.8064 | 2 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 39.5739 | 2 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 16.2618 | 2 | 4 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 23.1413 | 2 | 3 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 23.1413 | 2 | 3 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 62.3264 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 12.5690 | 2 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 45.9302 | 1 | 3 |