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guaiacols

Any phenol carrying an additional methoxy substituent at the ortho-position.

ChEBI ID: 134251

Members (16)

MemberDefinitionRole
(2S,3R)-dihydrodehydrodiconiferyl alcohol(2S,3R)-dihydrodehydrodiconiferyl alcohol
2-vanillinA member of the class of benzaldehydes that is salicylaldehyde substituted by a methoxy group at position 3.ortho-vanillin
4-hydroxy-3-methoxybenzene-1-sulfonic acidAn arenesulfonic acid that is guaiacol sulfated at position 4. Commonly used (in the form of its potassium salt) as an expectorant.4-hydroxy-3-methoxybenzene-1-sulfonic acid
coniferaldehydeA member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3.coniferyl aldehyde
coniferyl alcoholA phenylpropanoid that is one of the main monolignols, produced by the reduction of the carboxy functional group in cinnamic acid and the addition of a hydroxy and a methoxy substituent to the aromatic ring.coniferol
dehydrodiconiferyl alcoholA guaiacyl lignin obtained by cyclodimerisation of coniferol.dehydrodiconiferyl alcohol
dihydroferulic acidA monocarboxylic acid that is propanoic acid in which one of the hydrogens at position 3 has been replaced by a 4-hydroxy-3-methoxyphenyl group.dihydroferulic acid
gingerolA beta-hydroxy ketone that is 5-hydroxydecan-3-one substituted by a 4-hydroxy-3-methoxyphenyl moiety at position 1; believed to inhibit adipogenesis. It is a constituent of fresh ginger.gingerol
guaiacolA monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.guaiacol
hetacillinA lignan that consists of tetrahydrofuran substituted by a 3,4-dihydroxyphenyl group at position 2, a hydroxymethyl group at position 3 and a 4-hydroxy-3-methoxybenzyl group at position 4. It has been isolated from Taxus yunnanensis.taxiresinol
homovanillic acidA monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.homovanillic acid
isolariciresinolA lignan that is 5,6,7,8-tetrahydronaphthalen-2-ol substituted by hydroxymethyl groups at positions 6 and 7, a methoxy group at position 3 and a 4-hydroxy-3-methoxyphenyl group at position 8. It has been isolated from the roots of Rubia yunnanensis.(+)-isolariciresinol
meso-dihydroguaiaretic acidA lignan that is 2,3-dimethylbutane substituted by 2-methoxyphenol groups at positions 1 and 4 respectively. It has been isolated from the bark of Machilus robusta.meso-dihydroguaiaretic acid
methyl ferulateA cinnamate ester that is the methyl ester of ferulic acid. It has been isolated from Pisonia aculeata.trans-methylferulate
N-octylhomovanillamideA monocarboxylic acid amide that is the N-octyl amide of homovanillic acid.N-octylhomovanillamide
vanillyl alcoholA monomethoxybenzene that is 2-methoxyphenol substituted by a hydroxymethyl group at position 4.vanillyl alcohol

Research

Studies (8,511)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,217 (37.80)18.7374
1990's1,992 (23.41)18.2507
2000's1,414 (16.61)29.6817
2010's1,465 (17.21)24.3611
2020's423 (4.97)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials346 (3.84%)5.53%
Reviews248 (2.76%)6.00%
Case Studies199 (2.21%)4.05%
Observational2 (0.02%)0.25%
Other8,204 (91.17%)84.16%