Furrow Keratitis

A form of herpetic keratitis characterized by the formation of small vesicles which break down and coalesce to form recurring dendritic ulcers, characteristically irregular, linear, branching, and ending in knoblike extremities. (Dictionary of Visual Science, 3d ed)

Synonym
Keratitis, Furrow
Keratitis, Dendritic
Furrow Keratitis

Excerpt	Reference
"A case of herpes simplex dendritic keratitis is presented along with its treatment."	( Terry, JE, 1979)
"Twenty patients with dendritic keratitis were treated in a double-blind analysis study with either phosphonoformate 3% or trifluorthymidine 1% drops."	( Behrens-Baumann, W, 1992)
"Under BVDU therapy, dendritic keratitis in 44 patients healed within an average 7."	( De Clercq, E; Maudgal, PC, 1991)
"Significant progress in the treatment of dendritic keratitis is to be expected as soon as high-titer interferon preparations become commercially available."	( Sundmacher, R, 1985)
"We treated 32 patients with dendritic keratitis with a combination of acyclovir 3% ointment and vidarabine 3% ointment or acyclovir and placebo."	( Chastel, C; Colin, J; Kaufman, HE; Kissling, GE, 1987)
"Thirty-four patients with herpes simplex dendritic keratitis were randomized into three treatment categories: Group A had débridement alone; group B, trifluridine (trifluorothymidine) alone; and group C, débridement and trifluridine."	( Cohen, EJ; Dreizen, NG; Galentine, PG; Laibson, PR; Parlato, CJ; Sakauye, CM, 1985)
"23 patients with proven herpetic dendritic keratitis have been treated with combined blunt spatula debridement and trifluorothymidine."	( Herbort, CP; Matter, M, 1985)
"In one patient recurrence of dendritic keratitis, 5 weeks after scraping, was treated by topical bromovinyldeoxyuridine eye drops."	( Maudgal, PC; Missotten, L; Van Damme, B, 1983)
"Fourty-three eyes with active dendritic keratitis, nearly one third of which had failed to respond to other antiviral agents, were treated with acyclovir with or without preceding debridement."	( Jensen, KB; Jessen, F; Nissen, SH, 1982)
"We treated 25 patients with dendritic keratitis with debridement and 3% acyclovir ointment and another 25 with acyclovir alone."	( Coster, DJ; Jones, BR; Wilhelmus, KR, 1981)
"We treated two patients with dendritic keratitis that did not respond to acyclovir (ACV) ointment therapy."	( Inoue, Y; Kase, T; Mori, Y; Ohashi, Y; Uchihori, Y; Yao, YF, 1996)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	968 (90.55)	23.3326
1990's	70 (6.55)	12.5806
2000's	17 (1.59)	18.1394
2010's	12 (1.12)	28.8240
2020's	2 (0.19)	9.53

Drug	Relationship Strength	Studies	Trials
dinitrochlorobenzene	low	1	0
adenine	medium	12	4
ammonium hydroxide	low	1	0
phosphonoacetic acid	low	6	0
cytosine	low	5	0
dimethyl sulfoxide	low	4	0
glycerol	low	2	0
iodine	medium	19	2
orotic acid	low	1	0
purine	low	1	0
pyridoxal phosphate	low	1	0
selenious acid	low	1	0
thymine	low	1	0
uracil	low	10	0
acetazolamide	low	1	0
amantadine	medium	17	4
aristolochic acid i	low	1	0
aspirin	low	2	0
azathioprine	low	1	0
berberine	low	1	0
betaxolol	low	1	0
chlorambucil	low	1	0
chloroquine	low	3	0
cimetidine	low	1	0
diclofenac	low	2	0
dipivefrin	low	1	0
erythrosine	medium	20	2
brl 42810	low	1	0
fluorouracil	low	3	0
flurbiprofen	low	4	0
foscarnet	medium	3	1
gentamicin	low	5	0
guanidine	low	1	0
p-hydroxyamphetamine	low	1	0
hydroxyurea	low	1	0
indomethacin	medium	7	2
2-propanol	medium	26	1
mechlorethamine	low	1	0
methenamine	low	1	0
ethylmaleimide	low	1	0
naphazoline	low	2	0
ofloxacin	low	1	0
oxidopamine	low	9	0
oxyphenbutazone	medium	3	2
phenacetin	low	1	0
phenylbutazone	low	1	0
potassium iodide	low	1	0
procaine	low	1	0
rimantadine	medium	3	2
sulfadiazine	low	2	0
sulfacetamide	low	1	0
sulfaphenazole	low	1	0
tetracaine	low	1	0
tolmetin	low	1	0
tropicamide	low	1	0
corticosterone	medium	2	1
prednisolone	medium	33	3
cephaloridine	low	1	0
thymidine	medium	76	24
floxuridine	low	4	0
bromouracil	low	1	0
hydroxyproline	low	2	0
prednisolone acetate	low	2	0
penicillamine	low	2	0
prednisone	low	8	0
methylprednisolone acetate	low	1	0
azauridine	low	1	0
penicillin g	low	1	0
idoxuridine	medium	383	44
pilocarpine	low	2	0
biguanides	low	4	0
chloramphenicol	medium	12	1
lysine	low	1	0
uridine	medium	10	1
kanamycin a	low	1	0
bromodeoxyuridine	medium	29	4
edetic acid	low	2	0
tyrosine	low	11	0
adenosine monophosphate	low	4	0
phenylalanine	medium	5	2
cytidine	low	2	0
cycloheximide	low	1	0
ampicillin	low	1	0
mannitol	low	2	0
cytarabine	medium	34	1
trifluridine	medium	114	34
valine	low	2	0
threonine	low	1	0
methandrostenolone	low	1	0
tryptophan	low	1	0
arginine	low	2	0
trichloroacetic acid	low	1	0
triamcinolone acetonide	low	3	0
tromethamine	low	1	0
isoprene	low	1	0
methylprednisolone	low	6	0
n-vinyl-2-pyrrolidinone	low	3	0
3,3'-diaminobenzidine	low	1	0
proflavine	medium	4	1
xanthenes	low	1	0
pyrroles	low	1	0
framycetin	low	7	0
3-amino-9-ethylcarbazole	low	1	0
uridine diphosphate glucose	low	1	0
acridines	low	8	0
thiazoles	low	2	0
pyrazines	low	1	0
dexamethasone 21-phosphate	medium	3	1
betamethasone	medium	12	4
fluorometholone	low	2	0
2-aminopurine	low	1	0
fusarium	low	2	0
medroxyprogesterone	low	3	0
luminol	low	1	0
malondialdehyde	low	3	0
neutral red	medium	2	1
erythromycin	low	3	0
deoxycytidine	medium	5	2
deoxyuridine	low	35	0
bucrylate	low	1	0
nsc 65346	low	1	0
fluorescein	low	4	0
streptomycin	low	3	0
nitracrine	low	1	0
vantocil	low	1	0
dihydrostreptomycin sulfate	low	1	0
vidarabine	medium	128	41
enbucrilate	low	1	0
mercury	low	1	0
promethium	low	1	0
silver	low	2	0
argon	low	3	0
zinc sulfate	low	2	0
silver nitrate	low	5	0
fluorine	medium	6	3
ancitabine	low	5	0
trolamine salicylate	low	2	0
coformycin	low	2	0
levamisole	medium	20	1
cromolyn sodium	medium	2	1
iodine	low	4	0
phenyl acetate	low	3	0
triamcinolone	low	1	0
timolol	low	7	0
vidarabine phosphate	medium	4	1
pirprofen	medium	2	1
substance p	low	2	0
ribavirin	medium	9	1
lentinan	low	1	0
bezafibrate	low	1	0
levobunolol	low	1	0
denotivir	low	1	0
fiacitabine	low	1	0
fomesafen	low	1	0
adefovir	low	1	0
cidofovir anhydrous	low	3	0
propamidine	low	1	0
thymine arabinoside	low	1	0
ibacitabine	medium	4	2
3-hydroxynorvaline	low	1	0
5'-amino-2',5'-dideoxythymidine	low	1	0
cephalosporin c	low	1	0
edoxudin	low	1	0
triazoles	low	1	0
delphinidin	low	1	0
5-iodouracil	low	1	0
clobetasone butyrate	low	2	0
voriconazole	low	1	0
moroxydine	low	1	0
ketorolac tromethamine	low	1	0
5-bromouridine	low	1	0
homocysteine	low	1	0
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
deoxyglucose	low	6	0
5-methoxymethyl-2'-deoxyuridine	low	1	0
5-vinyl-1-arabinofuranosyluracil	low	2	0
methotrexate	low	2	0
2-(2-hydroxy-4-methylphenyl)aminothiazole	low	1	0
biotin	low	1	0
atropine	low	7	0
organophosphonates	low	4	0
5'-deoxy-5'-iodouridine	low	19	0
cortisone	medium	17	1
benzofurans	low	1	0
2'-fluorothymidine	low	1	0
s-adenosylhomocysteine	medium	2	1
glycogen	low	1	0
arabinose	medium	14	4
glucosamine	low	4	0
puromycin	low	1	0
pentostatin	low	2	0
inositol 3-phosphate	low	1	0
erythromycin ethylsuccinate	low	1	0
arachidonic acid	low	1	0
retinol	low	6	0
tacrolimus	low	1	0
cocaine	low	1	0
brivudine	medium	24	4
dactinomycin	low	2	0
bromodeoxycytidine	medium	4	2
riboflavin	low	1	0
5-(2-chloroethyl)-2'-deoxyuridine	low	1	0
methisazone	low	4	0
thiouracil	low	1	0
capsaicin	low	1	0
quinine	low	2	0
cystine	low	1	0
alpha-chymotrypsin	low	5	0
calcitriol	low	1	0
leukotriene b4	low	1	0
thromboxane a2	low	1	0
retinol palmitate	low	1	0
amphotericin b	low	5	0
mangiferin	low	1	0
sorivudine	low	3	0
phenylephrine hydrochloride	low	5	0
clobetasol	low	2	0
latanoprost	low	1	0
isomangiferin	low	1	0
strontium	low	1	0
cysteine	low	1	0
strontium radioisotopes	low	1	0
selenium	low	1	0
phtiobuzone	low	2	0
5-(2-iodovinyl)-2'-deoxyuridine	low	1	0
beta-escin	low	1	0
amphotericin a	low	1	0
nystatin a1	low	1	0
scopadulcic acid b	low	1	0
scopolamine hydrobromide	medium	4	1
arabinofuranosyluracil	low	4	0
rifamycins	low	1	0
acid phosphatase	low	1	0
nad	low	1	0
thimerosal	low	1	0
iodouracil	low	4	0
bucladesine	low	1	0
glycolipids	low	1	0
colistin	low	1	0
methylcellulose	low	3	0
chondroitin	low	2	0
ascorbic acid	low	2	0
tetracycline	low	6	0
chlortetracycline	low	6	0
oxytetracycline, anhydrous	low	1	0
agar	medium	1	1
hyaluronoglucosaminidase	low	2	0
ginkgolide b	low	1	0
cyclosporine	low	1	0
orabase	low	1	0
muramidase	low	11	0
chondroitin sulfates	low	1	0
acyclovir	medium	193	63
cyclic gmp	low	1	0
guanosine monophosphate	low	1	0
guanine	medium	41	19
guanosine	medium	4	2
inosinic acid	low	2	0
inosine	medium	5	2
rifampin	low	4	0
ganciclovir	medium	15	1
valacyclovir	low	4	0
acyclovir triphosphate	medium	1	1
hypoxanthine arabinoside	low	1	0
acyclovir monophosphate	medium	1	1
9-(4-hydroxybutyl)guanine	low	1	0
inosine pranobex	medium	6	2
9-((2-hydroxy-1,3,2-dioxaphosphorinan-5-yl)oxymethyl)guanine p-oxide	low	1	0
alcian blue	low	2	0
eye	medium	93	1
concanavalin a	low	1	0
phenanthrenes	low	1	0

Protein Targets (1,476)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	38	0	0	38
Chain A, Cruzipain	13	0	0	13
regulator of G-protein signaling 4	12	0	0	12
Platelet-activating factor receptor	0	2	0	2
Inositol monophosphatase 1	7	0	0	7
Chain A, Beta-lactamase	17	0	0	17
thioredoxin reductase	41	0	0	41
aldehyde dehydrogenase 1 family, member A1	43	0	0	43
IDH1	25	0	0	25
Phosphatidylinositol 4-kinase alpha	0	2	0	2
Xanthine dehydrogenase/oxidase	0	2	0	2
Guanine nucleotide-binding protein G	6	0	0	6
TAR DNA-binding protein 43	17	0	0	17
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	18	0	0	18
RAR-related orphan receptor gamma	48	0	0	48
GLI family zinc finger 3	52	0	0	52
AR protein	74	0	0	74
retinoic acid nuclear receptor alpha variant 1	54	0	0	54
retinoid X nuclear receptor alpha	38	0	0	38
estrogen nuclear receptor alpha	87	0	0	87
peroxisome proliferator-activated receptor delta	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	34	0	0	34
activating transcription factor 6	22	0	0	22
v-jun sarcoma virus 17 oncogene homolog (avian)	25	0	0	25
Histone H2A.x	25	0	0	25
thyroid hormone receptor beta isoform a	18	0	0	18
heat shock protein beta-1	23	0	0	23
nuclear factor erythroid 2-related factor 2 isoform 1	51	0	0	51
lamin isoform A-delta10	50	0	0	50
Voltage-dependent calcium channel gamma-2 subunit	26	0	0	26
Glutamate receptor 2	27	0	0	27
Replicase polyprotein 1ab	0	4	3	7
Replicase polyprotein 1ab	0	6	3	9
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	22	0	0	22
Chain A, HADH2 protein	19	0	0	19
Chain B, HADH2 protein	19	0	0	19
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
Chain A, Ferritin light chain	14	0	0	14
Luciferase	17	0	0	17
acid sphingomyelinase	5	0	0	5
glp-1 receptor, partial	19	0	0	19
ClpP	3	0	0	3
TDP1 protein	62	0	0	62
Microtubule-associated protein tau	33	0	0	33
estrogen receptor 2 (ER beta)	24	0	0	24
nuclear receptor subfamily 1, group I, member 3	38	0	0	38
progesterone receptor	36	0	0	36
nonstructural protein 1	10	0	0	10
estrogen-related nuclear receptor alpha	62	0	0	62
farnesoid X nuclear receptor	28	0	0	28
pregnane X nuclear receptor	48	0	0	48
vitamin D (1,25- dihydroxyvitamin D3) receptor	33	0	0	33
euchromatic histone-lysine N-methyltransferase 2	59	0	0	59
aryl hydrocarbon receptor	30	0	0	30
thyroid stimulating hormone receptor	15	0	0	15
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	16	0	0	16
hemoglobin subunit beta	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	16	0	0	16
chromobox protein homolog 1	40	0	0	40
thyroid hormone receptor beta isoform 2	42	0	0	42
histone deacetylase 9 isoform 3	7	0	0	7
huntingtin isoform 2	8	0	0	8
mitogen-activated protein kinase 1	14	0	0	14
rac GTPase-activating protein 1 isoform a	0	1	0	1
geminin	55	0	0	55
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Cellular tumor antigen p53	42	0	0	42
Histamine H2 receptor	10	2	1	14
glucocorticoid receptor [Homo sapiens]	57	0	0	57
5-hydroxytryptamine receptor 2A	0	5	0	5
Dihydropyrimidine dehydrogenase [NADP(+)]	0	1	0	1
Thymidine kinase 2	0	2	0	2
Thymidine kinase, cytosolic	0	2	0	4
Thymidylate kinase	0	6	0	6
Thymidine kinase	0	9	0	10
Thymidine kinase, cytosolic	0	9	0	14
Thymidine kinase	0	1	0	1
Thymidine kinase	0	5	0	6
Thymidine kinase	0	2	0	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GALC protein	5	0	0	5
cytochrome P450 family 3 subfamily A polypeptide 4	38	0	0	38
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	20	0	0	20
Carbonic anhydrase	0	1	0	1
Bloom syndrome protein isoform 1	22	0	0	22
peripheral myelin protein 22	29	0	0	29
survival motor neuron protein isoform d	25	0	0	25
muscleblind-like protein 1 isoform 1	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	23	3	3	29
ATP-binding cassette sub-family C member 3	0	37	0	37
Multidrug resistance-associated protein 4	0	37	0	39
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	11	0	14
Carbonic anhydrase 12	0	3	1	9
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	59	0	59
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	10	1	19
Carbonic anhydrase 2	0	12	2	21
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	5	0	7
Carbonic anhydrase 3	0	2	1	8
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	14	0	16
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	4	0	5
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	4
Cytochrome P450 2C8	0	3	0	3
Cytochrome P450 2D6	0	10	0	10
Cytochrome P450 2A6	0	2	1	3
Cytochrome P450 2C9	0	17	0	19
Androgen receptor	0	9	0	9
Gamma-aminobutyric acid receptor subunit beta-1	23	3	3	29
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	23	3	3	29
Gamma-aminobutyric acid receptor subunit gamma-2	23	3	3	29
Gamma-aminobutyric acid receptor subunit alpha-5	23	3	3	29
Gamma-aminobutyric acid receptor subunit alpha-3	23	3	3	29
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	2	1	3
Carbonic anhydrase 4	0	6	1	11
Carbonic anhydrase 6	0	3	1	8
Gamma-aminobutyric acid receptor subunit gamma-1	23	3	3	29
Gamma-aminobutyric acid receptor subunit alpha-2	23	3	3	29
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	4	0	6
Serum paraoxonase/arylesterase 1	0	4	0	4
Dipeptidyl peptidase 4	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	23	3	3	29
Gamma-aminobutyric acid receptor subunit gamma-3	23	3	3	29
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	23	3	3	29
Adenosine receptor A2a	0	4	0	6
5-hydroxytryptamine receptor 2B	0	3	0	3
Sodium-dependent serotonin transporter	0	3	0	4
Delta-type opioid receptor	0	1	0	1
Cytochrome P450 2C19	0	8	0	8
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	5	1	11
Carbonic anhydrase	0	2	0	5
Kappa-type opioid receptor	0	1	1	3
Carbonic anhydrase 7	0	2	1	7
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	2	1	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	4
D(2) dopamine receptor	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-1	23	4	3	30
Gamma-aminobutyric acid receptor subunit beta-3	23	3	3	29
Gamma-aminobutyric acid receptor subunit beta-2	23	3	3	29
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	4	0	7
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	7	1	14
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	5
GABA theta subunit	23	3	3	29
Canalicular multispecific organic anion transporter 1	0	36	0	36
Carbonic anhydrase 4	0	3	0	3
Carbonic anhydrase 15	0	2	0	6
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	5
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	23	3	3	29
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	2	1	8
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	1	8
Smad3	11	0	0	11
alpha-galactosidase	5	0	0	5
flap endonuclease 1	15	0	0	15
DNA polymerase iota isoform a (long)	28	0	0	28
DNA topoisomerase 2-alpha	0	0	0	1
Acetylcholinesterase	0	4	0	4
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	10	0	0	10
phosphopantetheinyl transferase	25	0	0	25
GLS protein	18	0	0	18
thyroid stimulating hormone receptor	23	0	0	23
EWS/FLI fusion protein	25	0	0	25
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Solute carrier family 22 member 1	0	9	0	12
Bile salt export pump	0	9	0	9
Purine nucleoside phosphorylase	0	4	0	6
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2J2	0	9	0	9
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	9	0	14
Solute carrier family 22 member 8	0	6	0	12
Thymidine kinase	0	5	0	6
DNA polymerase subunit gamma-1	0	0	1	1
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
Phosphoribosyl pyrophosphate synthase-associated protein 2	0	1	0	2
Adenylate kinase isoenzyme 1	0	0	0	2
Adenylate kinase 2, mitochondrial	0	0	0	2
Adenosine deaminase	0	4	0	6
Capsid protein	0	0	1	1
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	29	0	0	29
importin subunit beta-1 isoform 1	10	0	0	10
snurportin-1	10	0	0	10
tumor susceptibility gene 101 protein	2	0	0	2
GTP-binding nuclear protein Ran isoform 1	6	0	0	6
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	19	0	0	19
Ataxin-2	25	0	0	25
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	2	0	2
Chain A, Ribonuclease pancreatic	0	2	0	2
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	4	0	5
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	1	1	2
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	2	2
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	1	1	2
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
ATP-dependent phosphofructokinase	20	0	0	20
acetylcholinesterase	17	0	0	17
NFKB1 protein, partial	9	0	0	9
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
putative alpha-glucosidase	1	0	0	1
histone acetyltransferase KAT2A isoform 1	16	0	0	16
Solute carrier family 22 member 2	0	7	0	10
Glutamate receptor ionotropic, NMDA 2D	0	1	1	2
Glutamate receptor ionotropic, NMDA 3B	0	1	1	2
Matrix protein 2	0	1	2	3
Matrix protein 2	0	2	3	5
Glutamate receptor ionotropic, NMDA 1	0	3	0	6
Spike glycoprotein	23	1	3	27
Glutamate receptor ionotropic, NMDA 2A	0	3	0	6
Glutamate receptor ionotropic, NMDA 2C	0	3	0	6
Glutamate receptor ionotropic, NMDA 1	0	1	1	2
Glutamate receptor ionotropic, NMDA 2A	0	1	1	2
Glutamate receptor ionotropic, NMDA 2B	0	1	1	2
Glutamate receptor ionotropic, NMDA 2C	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	3	0	6
Solute carrier family 22 member 1	0	9	0	11
Glutamate receptor ionotropic, NMDA 3A	0	1	1	2
Glutamate receptor ionotropic, NMDA 3B	0	3	0	6
Multidrug and toxin extrusion protein 1	0	10	0	10
Solute carrier family 22 member 2	0	9	0	10
Glutamate receptor ionotropic, NMDA 3A	0	3	0	6
interleukin 8	17	0	0	17
tumor necrosis factor	3	0	0	3
vitamin D3 receptor isoform VDRA	23	0	0	23
Nuclear receptor ROR-gamma	14	0	0	14
Potassium voltage-gated channel subfamily H member 2	0	10	0	10
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	2
apical membrane antigen 1, AMA1	6	0	0	6
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
DNA polymerase beta	5	0	0	5
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase kappa isoform 1	19	0	0	19
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	9	0	10
Solute carrier family 15 member 1	0	3	0	3
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	4	0	4
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	1	0	3
Efflux transporter	0	0	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	0	0	3
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	5	0	5
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	5	0	6
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	5	0	5
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	1	0	3
cytochrome P450 2C19 precursor	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
15-lipoxygenase, partial	9	0	0	9
USP1 protein, partial	22	0	0	22
thioredoxin glutathione reductase	15	0	0	15
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
cellular tumor antigen p53 isoform a	12	0	0	12
nuclear receptor ROR-gamma isoform 1	20	0	0	20
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
cytochrome P450 3A4 isoform 1	23	0	0	23
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	4	0	0	4
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	5
Trypsin	0	1	0	2
Coagulation factor VII	0	1	0	1
60 kDa chaperonin	0	3	0	3
Aromatase	0	2	0	2
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	1	1	2
Prostaglandin G/H synthase 2	0	9	2	12
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Calmodulin	0	0	0	1
Prostaglandin G/H synthase 2	0	4	0	5
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Lanosterol 14-alpha demethylase	0	4	0	4
Solute carrier organic anion transporter family member 1B3	0	10	0	12
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	9	0	10
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
muscarinic acetylcholine receptor M1	13	0	0	13
lethal factor (plasmid)	9	0	0	9
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
urokinase-type plasminogen activator precursor	17	0	0	17
plasminogen precursor	17	0	0	17
urokinase plasminogen activator surface receptor precursor	17	0	0	17
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Cyclin-dependent kinase 2	0	1	1	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
Polyphenol oxidase 2	0	1	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	3	2	6
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	4	0	0	4
cytochrome P450 2D6	19	0	0	19
glucocerebrosidase	5	0	0	5
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	3
Epidermal growth factor receptor	0	4	0	4
Fatty acid-binding protein, liver	0	5	0	5
Integrin beta-3	6	1	0	7
Myeloperoxidase	0	2	0	2
Prostaglandin G/H synthase 1	0	7	0	8
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	6	1	0	7
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	7	0	7
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	4	0	4
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	3	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	6	1	7
Muscarinic acetylcholine receptor M2	0	11	3	17
Muscarinic acetylcholine receptor M4	0	9	1	12
Muscarinic acetylcholine receptor M1	0	8	2	13
Muscarinic acetylcholine receptor M3	0	6	2	11
Muscarinic acetylcholine receptor M4	0	6	2	11
Muscarinic acetylcholine receptor M5	0	6	2	11
Muscarinic acetylcholine receptor M5	0	9	1	12
Muscarinic acetylcholine receptor M2	0	7	3	14
Muscarinic acetylcholine receptor M1	0	11	4	18
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M3	0	9	2	13
Alpha-1D adrenergic receptor	0	4	2	7
5-hydroxytryptamine receptor 2C	0	6	1	7
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	0	3
Reverse transcriptase/RNaseH	0	2	2	5
Muscarinic acetylcholine receptor	0	1	1	2
SMAD family member 2	17	0	0	17
ATAD5 protein, partial	14	0	0	14
Fumarate hydratase	12	0	0	12
SMAD family member 3	17	0	0	17
G	24	0	0	24
polyprotein	12	0	0	12
P53	2	0	0	2
peroxisome proliferator activated receptor gamma	36	0	0	36
peripheral myelin protein 22 isoform 1	11	0	0	11
M-phase phosphoprotein 8	10	0	0	10
Interferon beta	36	0	0	36
HLA class I histocompatibility antigen, B alpha chain	24	0	0	24
Inositol hexakisphosphate kinase 1	24	0	0	24
Protein-arginine deiminase type-4	0	7	0	7
cytochrome P450 2C9, partial	24	0	0	24
Skn7p	0	0	0	2
67.9K protein	16	0	0	16
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Alpha-synuclein	4	4	0	8
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
PPM1D protein	8	0	0	8
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	18	0	0	18
cytochrome P450 2D6 isoform 1	7	0	0	7
Telomerase reverse transcriptase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Lysine-specific histone demethylase 1A	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Cholinesterase	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Aldo-keto reductase family 1 member C3	0	4	0	4
Prolyl endopeptidase	0	1	0	1
Aldo-keto reductase family 1 member C2	0	3	0	3
Cytochrome P450 1B1	0	3	0	3
pregnane X receptor	11	0	0	11
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	18	2	25
Glycine receptor subunit alpha-1	0	18	0	18
Glycine receptor subunit beta	0	18	0	18
Glycine receptor subunit alpha-2	0	18	0	18
Glycine receptor subunit alpha-3	0	18	0	18
ORF73	0	0	1	1
Beta-1 adrenergic receptor	0	1	3	5
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-1 adrenergic receptor	0	7	2	9
Beta-1 adrenergic receptor	0	3	2	6
5-hydroxytryptamine receptor 1A	0	7	4	12
Beta-2 adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	3	5
D(1A) dopamine receptor	4	0	0	4
Fatty acid-binding protein, intestinal	0	3	0	3
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	2
neuropeptide S receptor isoform A	7	0	0	7
relaxin receptor 1 isoform 1	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	11	0	0	11
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine phosphorylase	0	0	0	7
Thymidylate kinase	0	2	0	2
Thymidine kinase	0	0	0	6
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
relaxin receptor 2 isoform 1	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	3	1	4
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	1	1
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 22 member 8	0	5	0	6
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	1	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 7	0	1	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase IMP-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 11	0	2	0	4
Solute carrier family 22 member 7	0	1	0	2
Thrombopoietin	6	0	0	6
caspase 7, apoptosis-related cysteine protease	7	0	0	7
caspase-3	7	0	0	7
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
streptokinase A precursor	0	0	6	6
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	5	1	7
30S ribosomal protein S7	0	5	1	7
50S ribosomal protein L15	0	5	1	7
50S ribosomal protein L10	0	5	1	7
50S ribosomal protein L11	0	5	1	7
50S ribosomal protein L7/L12	0	5	1	7
50S ribosomal protein L19	0	5	1	7
50S ribosomal protein L1	0	5	1	7
50S ribosomal protein L20	0	5	1	7
50S ribosomal protein L27	0	5	1	7
50S ribosomal protein L28	0	5	1	7
50S ribosomal protein L29	0	5	1	7
50S ribosomal protein L31	0	5	1	7
50S ribosomal protein L31 type B	0	5	1	7
50S ribosomal protein L32	0	5	1	7
50S ribosomal protein L33	0	5	1	7
50S ribosomal protein L34	0	5	1	7
50S ribosomal protein L35	0	5	1	7
50S ribosomal protein L36	0	5	1	7
30S ribosomal protein S10	0	5	1	7
30S ribosomal protein S11	0	5	1	7
30S ribosomal protein S12	0	5	1	7
30S ribosomal protein S13	0	5	1	7
30S ribosomal protein S16	0	5	1	7
30S ribosomal protein S18	0	5	1	7
30S ribosomal protein S19	0	5	1	7
30S ribosomal protein S20	0	5	1	7
30S ribosomal protein S2	0	5	1	7
30S ribosomal protein S3	0	5	1	7
30S ribosomal protein S4	0	5	1	7
30S ribosomal protein S5	0	5	1	7
30S ribosomal protein S8	0	5	1	7
30S ribosomal protein S9	0	5	1	7
50S ribosomal protein L13	0	5	1	7
50S ribosomal protein L14	0	5	1	7
50S ribosomal protein L16	0	5	1	7
50S ribosomal protein L23	0	5	1	7
30S ribosomal protein S15	0	5	1	7
50S ribosomal protein L17	0	5	1	7
50S ribosomal protein L21	0	5	1	7
50S ribosomal protein L30	0	5	1	7
50S ribosomal protein L6	0	5	1	7
30S ribosomal protein S14	0	5	1	7
30S ribosomal protein S17	0	5	1	7
30S ribosomal protein S1	0	5	1	7
50S ribosomal protein L18	0	5	1	7
50S ribosomal protein L2	0	5	1	7
50S ribosomal protein L3	0	5	1	7
50S ribosomal protein L24	0	5	1	7
50S ribosomal protein L4	0	5	1	7
50S ribosomal protein L22	0	5	1	7
50S ribosomal protein L5	0	5	1	7
30S ribosomal protein S21	0	5	1	7
50S ribosomal protein L25	0	5	1	7
50S ribosomal protein L36 2	0	5	1	7
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
PAX8	0	0	0	1
PINK1	2	0	0	2
Parkin	5	0	0	5
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cytochrome P450 2C9 precursor	5	0	0	5
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
transcriptional regulator ERG isoform 3	7	0	0	7
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
protein AF-9 isoform a	0	0	0	1
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Synaptojanin-2	0	1	0	1
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	4	0	4
Glutathione reductase, mitochondrial	0	4	0	5
72 kDa type IV collagenase	0	2	0	2
Matrix metalloproteinase-9	0	2	0	2
Trypanothione reductase	0	3	0	3
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Rap guanine nucleotide exchange factor 4	1	0	0	1
Spermine oxidase	0	1	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	1	3	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	1	3	4
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	2	3	5
Major prion protein	0	0	2	2
Amyloid-beta precursor protein	1	5	0	6
Histidine-rich protein PFHRP-II	0	3	0	4
Procathepsin L	0	2	3	5
Alpha-2A adrenergic receptor	0	4	2	7
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	2	3	5
Spike glycoprotein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	5	3	9
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Beta-secretase 1	0	2	1	3
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	3	4
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Solute carrier family 22 member 1	0	2	0	2
Solute carrier family 22 member 2	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	8	1	11
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Histamine H2 receptor	0	4	0	4
Histamine H1 receptor	0	0	3	3
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	2	0	2
Histamine H4 receptor	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
D	0	1	0	1
Alpha-2B adrenergic receptor	0	2	1	3
Alpha-2C adrenergic receptor	0	2	1	3
Alpha-2A adrenergic receptor	0	2	1	3
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent noradrenaline transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
5-hydroxytryptamine receptor 1B	0	7	1	8
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Sodium-dependent serotonin transporter	0	6	0	6
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Leukotriene B4 receptor 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Transporter	0	3	0	3
Adenosine deaminase	0	2	0	2
AMP deaminase 3	0	1	0	1
Adenosine deaminase	0	2	0	2
Solute carrier family 22 member 3	0	1	0	1
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	2	2	4
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
endonuclease IV	6	0	0	6
dopamine D1 receptor	4	0	0	4
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
RPL19A	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
ras-related protein Rab-9A	4	0	0	4
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
COUP transcription factor 2 isoform a	0	1	0	1
Glucose transporter	0	2	0	2
Hexose transporter 1	0	2	0	2
Solute carrier family 2, facilitated glucose transporter member 1	0	2	0	2
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	1	5
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	2
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	4	0	4
Thymidylate synthase	0	4	0	7
Thymidine kinase	0	3	0	3
Deoxycytidine kinase	0	0	0	3
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	2	0	5
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	3	0	3
Cdk-related protein kinase 6	0	1	0	1
Protein kinase domain-containing protein	0	1	0	1
Calcium-dependent protein kinase 1	0	1	0	1
Mitogen-activated protein kinase	0	1	0	1
Proline--tRNA ligase	0	1	0	1
Calcium-dependent protein kinase 4	0	1	0	1
Lysine--tRNA ligase	0	1	0	1
Uridine-cytidine kinase 1	0	0	0	2
Deoxycytidine kinase	0	0	0	1
Rap guanine nucleotide exchange factor 3	8	0	0	8
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
RAD51	0	1	0	1
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	3	0	0	3
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Lactoylglutathione lyase	0	3	0	3
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
AAA family ATPase	0	0	0	1
Chain A, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	6	0	7
Cytochrome c oxidase subunit 2	0	2	0	2
Transthyretin	0	0	1	3
Albumin	0	4	7	11
Interleukin-8	0	3	0	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	3	0	6
UDP-glucuronosyltransferase 1-6	0	4	0	4
UDP-glucuronosyltransferase 1A1	0	4	0	4
UDP-glucuronosyltransferase 1A4	0	3	0	4
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	2
UDP-glucuronosyltransferase 2B10	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Prostaglandin G/H synthase 1	0	4	0	4
P2Y purinoceptor 12	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	6	0	6
Vpr	4	0	0	4
Glutathione S-transferase omega-1	0	2	0	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	3	0	3
exodeoxyribonuclease V subunit RecB	0	3	0	3
exodeoxyribonuclease V subunit RecC	0	3	0	3
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	4	0	0	4
Motilin receptor	0	1	1	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
thyrotropin-releasing hormone receptor	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	2	0	2
Ghrelin O-acyltransferase	0	1	0	1
Monoglyceride lipase	0	1	0	1
14 kDa phosphohistidine phosphatase	0	1	0	1
interferon gamma precursor	0	0	0	1
Sodium/nucleoside cotransporter 2	0	3	0	3
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Neuronal acetylcholine receptor subunit alpha-4	3	1	0	4
Neuronal acetylcholine receptor subunit beta-2	3	1	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	3
Acid-sensing ion channel 3	0	1	0	1
Aldo-keto reductase family 1 member C4	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Aldo-keto reductase family 1 member C1	0	2	0	2
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
DNA polymerase delta catalytic subunit	0	1	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	3
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Guanine deaminase	0	0	0	1
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Chain A, Membrane lipoprotein tmpC	0	0	2	2
Adenosylhomocysteinase	0	2	0	6
Chain A, Hypoxanthine Phosphoribosyltransferase	0	2	0	2
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE	0	2	0	2
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	2	2
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	2	2
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE	0	0	2	2
Chain A, Xanthine phosphoribosyltransferase	0	0	1	1
Histidine triad nucleotide-binding protein 1	0	0	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
Stromelysin-1	0	2	1	3
Urease subunit alpha	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Phospholipase A2, major isoenzyme	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	1	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, ADENOSINE DEAMINASE	0	1	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	3	3
Chain A, hypoxanthine phosphoribosyltransferase	0	0	1	1
Chain A, hypoxanthine phosphoribosyltransferase	0	0	1	1
Chain A, Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
5'-nucleotidase	0	2	0	2
Phospholipase A-2-activating protein	0	3	0	3
Beta-2 adrenergic receptor	0	6	1	7
Beta-3 adrenergic receptor	0	6	1	7
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
Queuine tRNA-ribosyltransferase	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Beta-glucuronidase	0	1	0	1
Sialidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Alpha-1A adrenergic receptor	0	1	3	5
Alpha-1B adrenergic receptor	0	0	2	3
Nischarin	0	1	0	1
Chain A, G protein-coupled receptor kinase 6	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Adenosine kinase	0	1	0	1
Adenosine kinase	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	3	1	4
STE24	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Nrf2	2	0	0	2
Microphthalmia-associated transcription factor	0	0	0	1
caspase recruitment domain family, member 15	0	2	0	2
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	2	0	2
Beta lactamase (plasmid)	0	2	0	2
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Trace amine-associated receptor 1	0	0	1	1
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Plasma kallikrein	0	0	0	3
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	5
SLC16A10 protein	0	0	0	3
Carbonic anhydrase-like protein, putative	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	3
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Chain A, Alkaline Phosphatase	0	1	0	1
Chain A, ALKALINE PHOSPHATASE	0	1	0	1
DNA polymerase III, partial	1	0	0	1
Fe(3+)-Zn(2+) purple acid phosphatase	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain H, ALPHA-THROMBIN	0	0	1	1
Chain A, Transcriptional regulator qacR	0	0	1	1
Chain A, Transcriptional regulator qacR	0	0	1	1
Chain A, TETR FAMILY TRANSCRIPTIONAL REPRESSOR LFRR	0	0	1	1
Prothrombin	0	1	0	1
Major pollen allergen Bet v 1-A	0	0	1	1
Acrosin	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Adenosine receptor A3	0	2	1	3
Beta-2 adrenergic receptor	0	2	0	3
D(2) dopamine receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	2	1	3
D(3) dopamine receptor	0	1	0	1
D(1A) dopamine receptor	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-1D adrenergic receptor	0	2	1	3
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	6	1	7
Adenosine receptor A2a	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Mu-type opioid receptor	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Delta-type opioid receptor	0	1	1	2
Kappa-type opioid receptor	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	1	3
Alpha-1A adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 6	0	2	1	3
Beta-2 adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium/bile acid cotransporter	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	1	0	1
P2X purinoceptor 4	0	0	1	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
P2X purinoceptor 2	0	0	1	1
N	0	1	0	1
NPYLR7B	0	0	2	2
Major prion protein	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
D(3) dopamine receptor	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Potassium channel subfamily K member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
NS5	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Adenine-n6-dna-methyltransferase Taqi	0	0	1	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Histamine N-Methyltransferase	0	1	0	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Modification Methylase Rsri	0	0	1	1
Chain A, Ermc' Methyltransferase	0	1	0	1
Chain A, Ermc' Rrna Methyltransferase	0	1	0	1
Chain A, Uroporphyrin-III C-methyltransferase	0	1	0	1
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase	0	0	1	1
tRNA (cytosine(38)-C(5))-methyltransferase	0	1	1	2
Protein arginine N-methyltransferase 5	0	1	0	1
Histone-lysine N-methyltransferase SUV39H1	0	2	0	2
Adenosylhomocysteinase	0	0	0	1
Protein arginine N-methyltransferase 3	0	1	0	1
Indolethylamine N-methyltransferase	0	1	0	1
Histone-lysine N-methyltransferase NSD2	0	1	0	1
Adenosylhomocysteinase	0	0	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
Phenylethanolamine N-methyltransferase	0	1	0	1
rRNA adenine N-6-methyltransferase	0	1	0	1
Catechol O-methyltransferase	0	0	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Nicotinamide N-methyltransferase	0	1	0	1
Fatty acid synthase	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Histone-lysine N-methyltransferase SETDB1	0	1	0	1
Retinoblastoma-binding protein 5	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N6-adenosine-methyltransferase catalytic subunit	0	1	0	1
Histone-arginine methyltransferase CARM1	0	1	0	1
Histone-lysine N-methyltransferase KMT5C	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Histone-lysine N-methyltransferase EZH1	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	2	0	2
Protein arginine N-methyltransferase 1	0	2	0	2
Methylosome protein 50	0	1	0	1
Protein dpy-30 homolog	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Histone-lysine N-methyltransferase SUV39H2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
N-lysine methyltransferase SMYD2	0	1	0	1
Protein arginine N-methyltransferase 7	0	1	0	1
DNA (cytosine-5)-methyltransferase 3B	0	1	0	1
Set1/Ash2 histone methyltransferase complex subunit ASH2	0	1	0	1
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Non-structural protein 1	0	1	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	2	0	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Aurora kinase A	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
cGMP-gated cation channel alpha-1	0	0	1	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
toll-like receptor 9	0	1	0	1
neurotensin receptor type 1	0	0	1	1
Taste receptor type 2 member 38	0	0	1	2
Thymidine phosphorylase	0	0	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine phosphorylase	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Chain A, Cytidine Deaminase	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Equilibrative nucleoside transporter 2	0	2	0	2
Equilibrative nucleoside transporter 1	0	2	0	2
Solute carrier family 28 member 3	0	2	0	2
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 14	0	0	1	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Amine oxidase [flavin-containing] B	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Treatment

Research

Studies (1,069)

Protein Targets (1,476)

Furrow Keratitis

Synonyms(3)

Research Excerpts

Treatment

Research

Studies (1,069)

Drugs Studied (306)

Protein Targets (1,476)