A pyranone based on the structure of 2H-pyran-2-one and its substituted derivatives.
| Member | Definition | Role |
|---|
| (+-)-Dihydromethysticin | | (+/-)-Dihydromethysticin |
| 2-pyrone | The simplest member of the class of 2-pyranones that is 2H-pyran with an oxo substituent at position 2. | 2H-pyran-2-one |
| 2,4-dimethyl-6-oxo-N-[(2,4,6-trifluorophenyl)methyl]-3-pyrancarboxamide | | 2,4-dimethyl-6-oxo-N-[(2,4,6-trifluorophenyl)methyl]-3-pyrancarboxamide |
| 4-hydroxy-6-methyl-2-pyrone | | triacetate lactone |
| 5,6-dehydrokawain | | 5,6-Dehydrokawain |
| 6-pentylpyrone | | 6-n-Pentyl-alpha-pyrone |
| 7,8-dihydro-5,6-dehydrokawain | | Dihydro-5,6-dehydrokawain |
| 7,8-dihydromethysticin | | Dihydromethysticin |
| 7,8-Dihydroyangonin | | 7,8-Dihydroyangonin |
| citreoviridin | | Citreoviridin |
| cryptocaryol a | A member of the class of 2-pyranones that is 5,6-dihydro-2H-pyran-2-one substituted by a 2,4,6,8,10-pentahydroxypentacosyl group at position 6. It has been isolated from Cryptocarya species. | cryptocaryol A |
| dihydrokavain | | Dihydrokavain |
| dihydromonacolin l | A pyranone obtained by selective hydrogenation of the 4a,5-double bond in monacolin L. | dihydromonacolin L |
| fostriecin | A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines. | fostriecin |
| hispidin | Fungal metabolite first found in basidiomycete Inonotus hispidus (formerly Polyporus hispidus). | hispidin |
| kavain | | Kawain |
| kavain | | (R)-Kawain |
| methysticin | | Methysticin |
| methysticin | | (R)-Methysticin |
| mevastatin | A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. | mevastatin |
| ml 236a | A carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity. | compactin diol lactone |
| monacolin j | A polyketide that is monacolin L bearing an additional hydroxy substituent at position 8. | monacolin J |
| monacolin l | A polyketide that is 1-ethyl-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalene in which one of the methyl hydrogens from the ethyl group is replaced by a 4-hydroxy-6-ketopyran-2-yl group. | monacolin L |
| obolactone | A pyranone isolated from the trunk barks of Cryptocarya obovata and has been shown to exhibit cytotoxicity against the KB cell line. | obolactone |
| parasorbic acid | | Parasorbic acid |
| phoslactomycin b | | Phoslactomycin B |
| yangonin | | Yangonin |