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trihydroxyflavone
Any hydroxyflavone carrying three hydroxy groups at unspecified positions.
ChEBI ID: 27116
Members (47)
| Member | Definition | Role |
|---|---|---|
| 3-methylkaempferol | A trihydroxyflavone that is apigenin substituted by a methoxy group at position 3. | 3-methoxyapigenin |
| 3,3'-di-o-methylquercetin | A dimethoxyflavone that is quercetin in which the hydroxy groups at position 3 and 3' have been replaced by methoxy groups. It has been isolated from several plant species and exhibits anti-bacterial and anti-cancer properties. | 3,3'-dimethylquercetin |
| 3,7-dimethoxy-5,3',4'-trihydroxyflavone | A dimethoxyflavone that the 3,7-di-O-methyl derivative of quercetin. | 3',4',5-trihydroxy-3,7-dimethoxyflavone |
| 5,7,3'-trihydroxy-3,4'-dimethoxyflavone | A dimethoxyflavone that is the 3,4'-dimethyl ether derivative of quercetin. Isolated from Combretum quadrangulare, it exhibits antineoplastic activity. | quercetin 3,4'-dimethyl ether |
| apigenin | A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. It induces autophagy in leukaemia cells. | apigenin |
| artocarpin lectin | A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 5, 2', and 4', a methoxy group at position 7, a prenyl group at position 3 and a (1E)-3-methylbut-1-enyl group at position 6. Isolated from Artocarpus heterophyllus and Artocarpus integrifolia, it exhibits antineoplastic activity. | artocarpin |
| astragalin | A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage. | kaempferol 3-O-beta-D-glucoside |
| baicalein | A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. | baicalein |
| centaureidin | A trihydroxyflavone that consists of quercetagetin in which the hydroxy groups at positions 3, 6 and 4' have been replaced by methoxy groups. It has been isolated from Eremophila mitchellii and Athroisma proteiforme. | centaureidin |
| chrysoeriol | The 3'-O-methyl derivative of luteolin. | 4',5,7-trihydroxy-3'-methoxyflavone |
| chrysosplenol c | A trimethoxyflavone that is the 3,7,3'-trimethyl ether derivative of quercetagetin. | chrysosplenol C |
| cirsiliol | A dimethoxyflavone that is flavone substituted by methoxy groups at positions 6 and 7 and hydroxy groups at positions 5, 3' and 4' respectively. | cirsiliol |
| dexmedetomidine | A trimethoxyflavone that is the 3,6,7-trimethyl ether derivative of quercetagetin. | 3',4',5-trihydroxy-3,6,7-trimethoxyflavone |
| diosmetin | A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. | diosmetin |
| eupatin | A trimethoxyflavone that is quercetagetin methylated at positions 4', 6 and 7. | eupatin |
| galangin | A 7-hydroxyflavonol with additional hydroxy groups at positions 3 and 5 respectively; a growth inhibitor of breast tumor cells. | galangin |
| hispidulin | A monomethoxyflavone that is scutellarein methylated at position 6. | hispidulin |
| isorhamnetin 3-o-glucoside | A glycosyloxyflavone that is isorhamnetin substituted at position 3 by a beta-D-glucosyl residue. | isorhamnetin 3-O-beta-D-glucopyranoside |
| isorhamnetin-3-o-galactoside | A glycosyloxyflavone that is isorhamnetin substituted at position 3 by a beta-D-galactosyl residue. | isorhamnetin 3-O-beta-D-galactopyranoside |
| isoschaftoside | A C-glycosyl compound that is apigenin substituted at positions 6 and 8 by alpha-L-arabinopyranosyl and beta-D-glucosyl residues respectively. | isoschaftoside |
| isovitexin | A C-glycosyl compound that consists of apigenin substituted by a 1,5-anhydro-D-glucitol moiety at position 6. | isovitexin |
| jaceosidin | A trihydroxyflavone that is flavone with hydroxy groups at positions 5, 7 and 4' and methoxy groups at positions 3' and 6. Isolated from Salvia tomentosa and Artemisia asiatica, it exhibits anti-allergic, anti-inflammatory and apoptosis inducing activties. | jaceosidin |
| kaempferide | A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol. | kaempferide |
| kaempferol 3-O-beta-L-glucopyranoside | A kaempferol O-glucoside that is kaempferol attached to a beta-L-glucopyranosyl moiety at position 3 via a glycosidic linkage. | kaempferol 3-O-beta-L-glucopyranoside |
| kaempferol 3-o-rhamnoside | A glycosyloxyflavone that is kaempferol attached to an alpha-L-rhamnosyl residue at position 3 via a glycosidic linkage. | afzelin |
| kaempferol 3-o-sophoroside | A sophoroside that is kaempferol attached to a beta-D-sophorosyl residue at position 3 via a glycosidic linkage. | 2)-beta-D-glucoside.html>kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside |
| kaempferol 7-o-glucoside | A kaempferol O-glucoside that is kaempferol attached to a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | kaempferol 7-O-beta-D-glucopyranoside |
| kaempferol-3-o-galactoside | A beta-D-galactoside compound with a 4',5,7-trihydroxychromen-3-yl group at the anomeric position. | kaempferol 3-O-beta-D-galactoside |
| kaempferol-3-o-rutinoside | A kaempferol O-glucoside that is kaempferol attached to a rutinosyl [6-deoxy-alpha-L-mannosyl-(1->6)-beta-D-glucosyl] residue at position 3 via a glycosidic linkage. It has been isolated from the leaves of Solanum campaniforme. | kaempferol-3-rutinoside |
| kaempferol-7-methyl ether | A monomethoxyflavone that is the 7-methyl ether derivative of kaempferol. | rhamnocitrin |
| luteolin 4'-o-glucoside | A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. It has been isolated from Olea europaea. | luteolin-4'-O-beta-D-glucopyranoside |
| luteolin-7-glucoside | A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | luteolin 7-O-beta-D-glucoside |
| luteolin-7-glucuronide | A luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 7-position. | luteolin 7-O-beta-D-glucosiduronic acid |
| morusin | An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8. | morusin |
| muromonab-cd3 | An extended flavonoid that consists of a pyranochromane skeleton that is 2H,6H-pyrano[3,2-g]chromen-6-one substituted by geminal methyl groups at position 2, a 2,4-dihydroxyphenyl group at position 8, a hydroxy group at position 5 and a prenyl group at position 7. Isolated from Morus alba and Morus species it exhibits anti-inflammatory activity. | cudraflavone B |
| narcissin flavonol | isorhamnetin-3-O-rutinoside | |
| norwogonin | A trihydroxyflavone with the hydroxy groups at positions C-5, -7 and -8. | norwogonin |
| ombuine | A dimethoxyflavone that is quercetin in which the hydroxy groups at positions 7 and 4' are replaced by methoxy groups. Isolated from Cyperus teneriffae, it exhibits anti-inflammatory activity. | ombuin |
| quercetin 3-o-glucoside-7-o-rhamnoside | A quercetin O-glucoside that is quercetin attached to beta-D-glucopyranosyl residue at position 3 and a alpha-L-rhamnopyranosyl residue at position 7 via glycosidic linkages. Isolated from the aerial parts of Delphinium staphisagria, it exhibits trypanocidal activity. | petiolaroside |
| rhamnazin | A dimethoxyflavone that is quercetin in which the hydroxy groups at the 3' and 7 positions have been replaced by methoxy groups. | rhamnacene |
| scutellarin | The glycosyloxyflavone which is the 7-O-glucuronide of scutellarein. | scutellarin |
| tiliroside | A glycosyloxyflavone that is kaempferol attached to a 6-O-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. | tribuloside |
| tricin | The 3',5'-di-O-methyl ether of tricetin. Known commonly as tricin, it is a constituent of rice bran and has been found to potently inhibit colon cancer cell growth. | 3',5'-di-O-methyltricetin |
| veronicastroside | A disaccharide derivative that is luteolin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. | luteolin 7-O-neohesperidoside |
| vicenin ii | A C-glycosyl compound that is isovitexin in which the hydrogen at position 8 is replaced by a beta-D-glucosyl residue. | isovitexin 8-C-beta-glucoside |
| vitexin | An apigenin flavone glycoside, which is found in the passion flower, bamboo leaves and pearl millet | vitexin |
| vitexin rhamnoside | A derivative of vitexin having an alpha-L-rhamnosyl residue attached at the 2''-position of the glucitol moiety. | vitexin 2''-O-alpha-L-rhamnoside |
Research
Studies (6,164)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 122 (1.98) | 18.7374 |
| 1990's | 300 (4.87) | 18.2507 |
| 2000's | 1,349 (21.89) | 29.6817 |
| 2010's | 3,098 (50.26) | 24.3611 |
| 2020's | 1,295 (21.01) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 94 (1.22%) | 5.53% |
| Reviews | 276 (3.57%) | 6.00% |
| Case Studies | 27 (0.35%) | 4.05% |
| Observational | 4 (0.05%) | 0.25% |
| Other | 7,333 (94.82%) | 84.16% |