Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond.
| Member | Definition | Role |
|---|
| (2'-(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic acid 2-(2-pyridyl)ethylamide) | | S9947 |
| (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol | | (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]-6-purinyl]amino]-3-phenyl-1-propanol |
| (3R,3aS,7R,7aS)-3-[4-[4-(dimethylamino)phenyl]-2-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one | | (3R,3aS,7R,7aS)-3-[4-[4-(dimethylamino)phenyl]-2-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one |
| 1-(4-morpholinyl)-2-(4-phenylphenoxy)-1-propanone | | 1-(4-morpholinyl)-2-(4-phenylphenoxy)-1-propanone |
| 1-[3-(4-phenylphenoxy)propyl]-1,2,4-triazole | | 1-[3-(4-phenylphenoxy)propyl]-1,2,4-triazole |
| 2-(2-phenylanilino)-N-(phenylmethyl)acetamide | | 2-(2-phenylanilino)-N-(phenylmethyl)acetamide |
| 2-(2,5-dimethoxyphenyl)-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazole | | 2-(2,5-dimethoxyphenyl)-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazole |
| 2-(4-benzoyl-1-piperazinyl)-N-(2-phenylphenyl)propanamide | | 2-(4-benzoyl-1-piperazinyl)-N-(2-phenylphenyl)propanamide |
| 2-(4-morpholinyl)-N-(2-phenylphenyl)propanamide | | 2-(4-morpholinyl)-N-(2-phenylphenyl)propanamide |
| 2-(4-phenylphenoxy)propanoic acid | | 2-(4-phenylphenoxy)propanoic acid |
| 2-[(1-methyl-5-tetrazolyl)thio]-N-(2-phenylphenyl)acetamide | | 2-[(1-methyl-5-tetrazolyl)thio]-N-(2-phenylphenyl)acetamide |
| 2-[(3,4-dimethoxyphenyl)methyl]-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazole | | 2-[(3,4-dimethoxyphenyl)methyl]-5-[4-(4-methoxyphenyl)phenyl]-1,3,4-oxadiazole |
| 2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid | | 2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-3-methylbutanoic acid |
| 2-amino-4-phenylphenol | | 2-amino-4-phenylphenol |
| 2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide | A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including Botrytis spp., Alternaria spp. and Sclerotinia spp. for use on a wide range of crops including fruit, vegetables and ornamentals. | boscalid |
| 2-phenylbutanoic acid [2-oxo-2-(2-phenylanilino)ethyl] ester | | 2-phenylbutanoic acid [2-oxo-2-(2-phenylanilino)ethyl] ester |
| 2-tolidine | | 3,3'-Dimethylbenzidine |
| 3-(4-phenylphenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine | | 3-(4-phenylphenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine |
| 3-[4-[(2-hydroxy-5-phenylphenyl)methyl]-1-piperazinyl]propanenitrile | | 3-[4-[(2-hydroxy-5-phenylphenyl)methyl]-1-piperazinyl]propanenitrile |
| 3-phenyl-5-(2-phenylphenyl)-1,2,4-oxadiazole | | 3-phenyl-5-(2-phenylphenyl)-1,2,4-oxadiazole |
| 3,3'-diaminobenzidine | A member of the class of biphenyls that is benzidine in which one of the hydrogens ortho to each of the amino groups has been replaced by an amino group. | 3,3'-diaminobenzidine |
| 3,3'-dichlorobenzidine | | 3,3'-Dichlorobenzidine |
| 3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide | | 3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide |
| 4-(2-fluorophenyl)-N-(2-methylbut-3-yn-2-yl)benzamide | | 4-(2-fluorophenyl)-N-(2-methylbut-3-yn-2-yl)benzamide |
| 4-(4-acetyloxyphenyl)benzoic acid [2-[[2-(2-chloroanilino)-2-oxoethyl]-methylamino]-2-oxoethyl] ester | | 4-(4-acetyloxyphenyl)benzoic acid [2-[[2-(2-chloroanilino)-2-oxoethyl]-methylamino]-2-oxoethyl] ester |
| 4-[(1-methyl-5-tetrazolyl)thio]-5-(4-phenylphenyl)thieno[2,3-d]pyrimidine | | 4-[(1-methyl-5-tetrazolyl)thio]-5-(4-phenylphenyl)thieno[2,3-d]pyrimidine |
| 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide | | 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide |
| 4-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]benzonitrile | | 4-[4-[2-hydroxy-3-(4-morpholinyl)propoxy]phenyl]benzonitrile |
| 4-acetylaminobiphenyl | | 4-Acetylaminobiphenyl |
| 4-biphenylylacetic acid | A monocarboxylic acid in which one of the alpha-hydrogens is substituted by a biphenyl-4-yl group. An active metabolite of fenbufen, it is used as a topical medicine to treat muscle inflammation and arthritis. | biphenyl-4-ylacetic acid |
| 4-biphenylylacetic acid ethyl ester | | Felbinac ethyl |
| 4-hydroxy-2',3',4'-5'-tetrachlorobiphenyl | | 2,3,4,5-Tetrachloro-4'-biphenylol |
| 4-hydroxy-2',4',6'-trichlorobiphenyl | | 2,4,6-Trichloro-4'-biphenylol |
| 4-nitrobiphenyl | | 4-Nitrobiphenyl |
| 4-phenyl-N-(2-propyl-5-tetrazolyl)benzamide | | 4-phenyl-N-(2-propyl-5-tetrazolyl)benzamide |
| 4-phenylbenzoic acid (propan-2-ylideneamino) ester | | 4-phenylbenzoic acid (propan-2-ylideneamino) ester |
| 4,4'-bis(methylsulfonyl)-2,2',5,5'-tetrachlorobiphenyl | An member of the class of biphenyls that is 2,2',5,5'-tetrachlorobiphenyl in which the 4 and 4' positions are substituted by methylsulfonyl groups. | 2,2',5,5'-tetrachloro-4,4'-bis(methylsulfonyl)biphenyl |
| 4'-hydroxyflurbiprofen | | 4'-Hydroxyflurbiprofen |
| 5-oxo-3-(4-phenylphenyl)-2H-furan-4-carbonitrile | | 5-oxo-3-(4-phenylphenyl)-2H-furan-4-carbonitrile |
| a 769662 | | 4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile |
| abt-737 | A biphenyl that is 4-chloro-1,1'-biphenyl substituted by a (4-{4-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene-1-sulfonyl)carbamoyl]phenyl}piperazin-1-yl)methyl group at position 2'. It is a BH3-mimetic drug which targets the anti-apoptotic B-cell lymphoma-2 (BCL-2) family proteins, including BCL-2, BCL-xL, and BCL-w, and induces apoptosis in cancer cells. | ABT-737 |
| ac 55649 | | 4-(4-octylphenyl)benzoic acid |
| alx 5407 | | 2-[[(3R)-3-(4-fluorophenyl)-3-(4-phenylphenoxy)propyl]-methylamino]acetic acid |
| aucuparin | | Aucuparin |
| bay 12-9566 | | Tanomastat |
| bay h 4502 | A member of the class of imidazoles carrying an alpha-(biphenyl-4-yl)benzyl substituent at position 1. | 1-[biphenyl-4-yl(phenyl)methyl]imidazole |
| benzidine | A member of the class of biphenyls that is 1,1'-biphenyl in which the hydrogen at the para-position of each phenyl group has been replaced by an amino group. | benzidine |
| bifeprunox | | Bifeprunox |
| biphenyl-indanone a | | Biphenylindanone a |
| bitertanol | A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O-1 by a biphenyl-4-yl group. | 1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol |
| bms-790052 | A member of the class of biphenyls that is a potent inhibitor of nonstructural protein 5A and is used (as its hydrochloride salt) for treatment of hepatitis C. | daclatasvir |
| brequinar | A quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties. | brequinar |
| candesartan cilexetil | | Candesartan cilexetil |
| clobuzarit | | clobuzarit |
| dehydrodieugenol | | Dehydrodieugenol |
| dianisidine | | 3,3'-Dimethoxybenzidine |
| difenpiramide | A monocarboxylic acid amide obtained by formal condensation of the carboxy group from biphenyl-4-ylacetic acid with the amino group of 2-aminopyridine. Used for treatment of rheumatoid arthritis. | difenpiramide |
| diphenyl | A benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. Formerly used as a fungicide for citrus crops. | biphenyl |
| dityrosine | A biphenyl compound comprising two tyrosine residues linked at carbon-3 of their benzene rings. | dityrosine |
| fenbufen | | fenbufen |
| fexaramine | | Fexaramine |
| fimasartan | | fimasartan |
| fluxapyroxad | An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families. | fluxapyroxad |
| honokiol | | Honokiol |
| isodiospyrin | | Isodiospyrin |
| l-161982 | | N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonyl-3-methyl-2-thiophenecarboxamide |
| lde225 | A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma. | sonidegib |
| ly2183240 | | N,N-dimethyl-5-[(4-phenylphenyl)methyl]-1-tetrazolecarboxamide |
| magnolol | | Magnolol |
| ml228 probe | A member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. | ML228 |
| N-([biphenyl]-2-yl)-3-cyclopentylpropanamide | A secondary carboxamide resulting from the formal condensation of the carboxy group of 3-cyclopentylpropionic acid with the amino group of [biphenyl]-2-amine. | N-([biphenyl]-2-yl)-3-cyclopentylpropanamide |
| N-(2-methoxyethyl)-4-[4-(2-methoxyethylsulfamoyl)phenyl]benzenesulfonamide | | N-(2-methoxyethyl)-4-[4-(2-methoxyethylsulfamoyl)phenyl]benzenesulfonamide |
| N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide | A member of the class of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)[1,1'-biphenyl]-4-carboxylic acid with the amino group of 3-cyanoaniline. | N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide |
| N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide | | N-[[(6-methyl-2-pyridinyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide |
| N-[[methyl-(phenylmethyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide | | N-[[methyl-(phenylmethyl)amino]-sulfanylidenemethyl]-4-phenylbenzamide |
| N-[2-(2-phenylphenoxy)ethyl]-2-furancarboxamide | | N-[2-(2-phenylphenoxy)ethyl]-2-furancarboxamide |
| N-[3-(3-chlorophenyl)phenyl]-1-(3-isoxazolylmethyl)-4-piperidinecarboxamide | | N-[3-(3-chlorophenyl)phenyl]-1-(3-isoxazolylmethyl)-4-piperidinecarboxamide |
| N-[3-(3-chlorophenyl)phenyl]-1-(3-oxolanylmethyl)-4-piperidinecarboxamide | | N-[3-(3-chlorophenyl)phenyl]-1-(3-oxolanylmethyl)-4-piperidinecarboxamide |
| N-[4-[4-(ethylsulfonylamino)-3-methoxyphenyl]-2-methoxyphenyl]ethanesulfonamide | | N-[4-[4-(ethylsulfonylamino)-3-methoxyphenyl]-2-methoxyphenyl]ethanesulfonamide |
| N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide | A dicarboxylic acid diamide obtained by condensation of the 3- and 4'-carboxy groups of 6-methyl[1,1'-biphenyl]-3,4'-dicarboxylic acid with cyclpropylamine and cyclpropylmethylamine respectively. | N-cyclopropyl-3-{4-[(cyclopropylmethyl)carbamoyl]phenyl}-4-methylbenzamide |
| n,n'-diacetylbenzidine | | N,N'-Diacetylbenzidine |
| nitroflurbiprofen | A carboxylic ester obtained by formal condensation of the carboxy group of flurbiprofen with the free hydroxy group of 4-(nitrooxy)butanol. It is a non-steroidal anti-inflammatory agent showing inhibitory effects against the cyclooxygenases COX1 and COX2. | nitroflurbiprofen |
| olmesartan medoxomil | | Olmesartan medoxomil |
| sacubitril | | sacubitril |
| tak-875 | | Fasiglifam |
| tasosartan | | tasosartan |
| telmisartan | A member of the class of benzimidazoles used widely in the treatment of hypertension. | telmisartan |
| urb 597 | | URB597 |
| WWL113 | | WWL113 |