Alopecia Mucinosa

A disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss. It is caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. It may be primary (idiopathic) or secondary to mycosis fungoides or reticulosis.

Synonym
Alopecia Mucinosa
Mucinosis, Follicular

Excerpt	Reference
"On the other hand, follicular mucinosis has been described in association with numerous processes, mainly lymphomas, lupus erythematosus and, less frequently, with photoinduced eruptions and drug reactions."	( Fortea, JM; Martínez-Menchón, T; Pérez-Ferriols, A, 2005)

Excerpt	Reference
"When associated with follicular mucinosis, mycosis fungoides commonly pursues an aggressive course, often undergoing large-cell transformation, which is associated with resistance to therapy and poor prognosis."	( Apisarnthanarax, N; Duvic, M; Ha, CS, 2003)
"No effective standard therapy for follicular mucinosis is available."	( Arca, E; Gür, AR; Köse, O; Safali, M; Taştan, HB, 2004)
"There exists no treatment of choice for follicular mucinosis (FM)."	( Bonsmann, G; Metze, D; Schneider, SW, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	16 (27.59)	23.3326
1990's	9 (15.52)	12.5806
2000's	14 (24.14)	18.1394
2010's	16 (27.59)	28.8240
2020's	3 (5.17)	9.53

Drug	Relationship Strength	Studies
aminolevulinic acid	low	2
salicylic acid	low	15
glycolic acid	low	1
histamine	low	1
carbamazepine	low	1
dapsone	low	4
hydroxychloroquine	low	2
indomethacin	low	1
mechlorethamine	low	1
prednisolone	low	2
prednisone	low	5
cytarabine	low	1
triamcinolone acetonide	low	1
pantothenic acid	low	1
meglumine	low	1
betamethasone	low	1
triamcinolone	low	1
oxcarbazepine	low	1
captopril	low	1
meglumine antimoniate	low	1
bexarotene	low	3
fibrinogen	low	1
imatinib mesylate	low	1
methotrexate	low	1
tretinoin	low	1
retinol	low	1
tacrolimus	low	2
melphalan	low	1
leuprolide	low	1
isotretinoin	low	3
phenylephrine hydrochloride	low	1
acitretin	low	2
clobetasol	low	1
acid phosphatase	low	1
chondroitin	low	1
tetracycline	low	1
minocycline	low	5
1 alpha,24-dihydroxyvitamin d3	low	1
hyaluronoglucosaminidase	low	1

Protein Targets (647)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Luciferase	6	0	0	6
USP1 protein, partial	11	0	0	11
TDP1 protein	21	0	0	21
Microtubule-associated protein tau	9	0	0	9
AR protein	23	0	0	23
aldehyde dehydrogenase 1 family, member A1	9	0	0	9
glucocorticoid receptor [Homo sapiens]	20	0	0	20
estrogen nuclear receptor alpha	24	0	0	24
peroxisome proliferator activated receptor gamma	13	0	0	13
euchromatic histone-lysine N-methyltransferase 2	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	14	0	0	14
vitamin D3 receptor isoform VDRA	9	0	0	9
thyroid hormone receptor beta isoform 2	15	0	0	15
flap endonuclease 1	2	0	0	2
serine/threonine-protein kinase PLK1	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	3	0	0	3
geminin	18	0	0	18
peripheral myelin protein 22	11	0	0	11
survival motor neuron protein isoform d	5	0	0	5
histone acetyltransferase KAT2A isoform 1	5	0	0	5
ATP-binding cassette sub-family C member 3	0	18	0	18
Multidrug resistance-associated protein 4	0	18	0	19
Bile salt export pump	0	5	0	5
Bile salt export pump	0	21	0	21
Rap guanine nucleotide exchange factor 3	1	0	0	1
Cellular tumor antigen p53	16	0	0	16
Rap guanine nucleotide exchange factor 4	2	0	0	2
Chain A, Beta-lactamase	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	2	0	2
Solute carrier family 15 member 2	0	1	0	1
pregnane X receptor	4	0	0	4
GLI family zinc finger 3	14	0	0	14
progesterone receptor	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	11	0	0	11
estrogen-related nuclear receptor alpha	16	0	0	16
farnesoid X nuclear receptor	8	0	0	8
pregnane X nuclear receptor	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	12	0	0	12
IDH1	6	0	0	6
aryl hydrocarbon receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
thyroid hormone receptor beta isoform a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	9
galanin receptor type 3	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	13	0	0	13
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glutamate receptor 2	10	0	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Canalicular multispecific organic anion transporter 1	0	17	0	17
ORF73	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
RAR-related orphan receptor gamma	11	0	0	11
SMAD family member 2	6	0	0	6
Fumarate hydratase	3	0	0	3
PPM1D protein	2	0	0	2
SMAD family member 3	6	0	0	6
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	11	0	0	11
EWS/FLI fusion protein	12	0	0	12
retinoic acid nuclear receptor alpha variant 1	11	0	0	11
retinoid X nuclear receptor alpha	11	0	0	11
G	6	0	0	6
polyprotein	3	0	0	3
peroxisome proliferator-activated receptor delta	10	0	0	10
caspase-3	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
thyroid stimulating hormone receptor	6	0	0	6
activating transcription factor 6	4	0	0	4
thyrotropin-releasing hormone receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	3	0	0	3
Histone H2A.x	5	0	0	5
Caspase-7	4	0	0	4
Bloom syndrome protein isoform 1	7	0	0	7
caspase-3	4	0	0	4
heat shock protein beta-1	7	0	0	7
nuclear receptor ROR-gamma isoform 1	8	0	0	8
Cytochrome P450 26A1	0	1	0	1
Interferon beta	9	0	0	9
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
Cytochrome P450 1A2	0	1	1	2
Cytochrome P450 3A4	0	3	1	5
Retinoic acid receptor alpha	0	3	4	10
Retinoic acid receptor beta	0	3	4	10
Retinoic acid receptor gamma	0	3	4	10
Retinoic acid receptor RXR-alpha	0	4	4	9
Retinoic acid receptor RXR-alpha	0	2	3	5
Retinoic acid receptor RXR-beta	0	3	3	6
Retinoic acid receptor RXR-beta	0	2	4	6
Retinoic acid receptor RXR-gamma	0	2	4	6
Type-1 angiotensin II receptor	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Retinoic acid receptor RXR-gamma	0	3	3	6
Type-2 angiotensin II receptor	0	0	1	1
Oxysterols receptor LXR-beta	0	0	1	1
Spike glycoprotein	9	0	1	10
Retinoic acid receptor RXR-alpha	0	0	1	1
Oxysterols receptor LXR-alpha	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
ATPase family AAA domain-containing protein 5	9	0	0	9
Ataxin-2	10	0	0	10
Cytochrome P450 26B1	0	1	0	1
cytochrome P450 2C9, partial	6	0	0	6
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
15-lipoxygenase, partial	4	0	0	4
phosphopantetheinyl transferase	8	0	0	8
Thrombopoietin	1	0	0	1
thioredoxin glutathione reductase	5	0	0	5
Metallo-beta-lactamase type 2	0	1	1	2
peripheral myelin protein 22 isoform 1	4	0	0	4
chromobox protein homolog 1	7	0	0	7
M-phase phosphoprotein 8	4	0	0	4
transient receptor potential cation channel subfamily V member 1	1	0	0	1
lamin isoform A-delta10	12	0	0	12
Prothrombin	0	1	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	2	1	3
Angiotensin-converting enzyme	0	2	0	3
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	5	1	6
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	0	1	1
TAR DNA-binding protein 43	4	0	0	4
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	1	1	2
Beta-lactamase class B VIM-2	0	1	1	2
ATP-dependent phosphofructokinase	4	0	0	4
acetylcholinesterase	3	0	0	3
thyroid stimulating hormone receptor	4	0	0	4
mitogen-activated protein kinase 1	2	0	0	2
Vpr	2	0	0	2
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2C9	0	4	1	5
UDP-glucuronosyltransferase 2B7	0	0	0	2
Cytochrome P450 2B6	0	0	1	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Cytochrome P450 2J2	0	4	0	4
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	2	0	2
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	6	0	0	6
endonuclease IV	1	0	0	1
glp-1 receptor, partial	5	0	0	5
thioredoxin reductase	11	0	0	11
67.9K protein	5	0	0	5
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
DNA polymerase iota isoform a (long)	7	0	0	7
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	1	0	2
D(1A) dopamine receptor	1	0	0	1
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
interleukin 8	3	0	0	3
Smad3	3	0	0	3
cytochrome P450 2C9 precursor	2	0	0	2
cytochrome P450 3A4 isoform 1	6	0	0	6
muscleblind-like protein 1 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	6	0	0	6
Myeloperoxidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	6	0	0	6
Dihydrofolate reductase	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	6	0	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	6	0	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	6	0	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	6	0	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	6	0	0	6
Histamine H2 receptor	2	0	1	3
5-hydroxytryptamine receptor 6	0	1	0	1
Nuclear receptor ROR-gamma	5	1	1	7
Gamma-aminobutyric acid receptor subunit alpha-1	6	0	0	6
Gamma-aminobutyric acid receptor subunit beta-3	6	0	0	6
Gamma-aminobutyric acid receptor subunit beta-2	6	0	0	6
GABA theta subunit	6	0	0	6
Gamma-aminobutyric acid receptor subunit epsilon	6	0	0	6
DNA polymerase kappa isoform 1	6	0	0	6
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	3	0	0	3
GLS protein	4	0	0	4
apical membrane antigen 1, AMA1	1	0	0	1
regulator of G-protein signaling 4	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 1	0	0	0	1
Carbonic anhydrase 12	0	1	0	2
Solute carrier family 22 member 3	0	1	0	2
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 2	0	2	1	5
Plasma kallikrein	0	0	0	1
Carbonic anhydrase 3	0	1	0	2
Macrophage migration inhibitory factor	0	2	0	2
Carbonic anhydrase 4	0	1	0	2
Carbonic anhydrase 6	0	1	0	2
Histamine H2 receptor	0	3	2	5
Adenosine receptor A1	0	1	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	1	0	2
Histamine H1 receptor	0	1	3	4
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Histamine H1 receptor	0	2	2	4
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase 7	0	1	0	2
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	1	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Solute carrier family 22 member 1	0	1	0	2
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 15	0	1	0	2
Carbonic anhydrase 13	0	1	0	2
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
Histamine H3 receptor	0	1	2	3
Genome polyprotein	0	1	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Procathepsin L	0	1	1	2
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Muscarinic acetylcholine receptor M1	0	1	0	1
Alpha-2B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Alpha-1D adrenergic receptor	0	4	0	4
Sigma intracellular receptor 2	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	1	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Tyrosine-protein kinase ABL1	0	1	2	3
Cytochrome P450 2C8	0	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	1	2
Breakpoint cluster region protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Cytochrome P450 3A5	0	1	0	2
cytochrome P450 2D6	3	0	0	3
DNA polymerase beta	2	0	0	2
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
Adenosine receptor A2a	0	2	0	2
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
Chain A, Cruzipain	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
glucocerebrosidase	2	0	0	2
Parkin	3	0	0	3
cytochrome P450 2D6 isoform 1	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	2
Prostaglandin G/H synthase 2	0	1	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Albumin	0	2	2	4
Prostaglandin G/H synthase 1	0	2	0	3
ATP-dependent translocase ABCB1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	1
Substance-P receptor	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 6	0	2	0	3
Solute carrier family 22 member 7	0	0	0	2
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 8	0	2	0	4
Multidrug and toxin extrusion protein 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	3	0	3
Chain A, Ferritin light chain	4	0	0	4
ATAD5 protein, partial	4	0	0	4
Ornithine decarboxylase	0	0	0	2
Adenosine receptor A3	0	4	0	4
Retinoic acid receptor alpha	0	2	2	4
Alpha-1B adrenergic receptor	0	5	0	5
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Mitogen-activated protein kinase 1	0	2	0	2
Cellular retinoic acid-binding protein 1	0	2	0	3
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	5	0	5
Cellular retinoic acid-binding protein 1	0	0	2	2
Mitogen-activated protein kinase 14	0	1	0	1
Olfactory receptor 51E2	0	1	0	1
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
dopamine D1 receptor	1	0	0	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
alpha-galactosidase	1	0	0	1
Thymidylate synthase	0	1	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
transcriptional regulator ERG isoform 3	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Integrin beta-3	1	0	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Integrin alpha-IIb	1	0	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	2
Protein-arginine deiminase type-4	0	4	0	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	2
Stromelysin-1	0	2	1	3
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
nonstructural protein 1	2	0	0	2
polyadenylate-binding protein 1	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
bcl-2-related protein A1	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Amyloid-beta precursor protein	0	2	0	2
Alpha-synuclein	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Cytochrome P450 2D6	0	0	1	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Cytochrome P450 2C19	0	0	1	1
Nuclear receptor ROR-alpha	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
NFKB1 protein, partial	1	0	0	1
arylsulfatase A	1	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Context

Treatment

Research

Studies (58)

Protein Targets (647)

Alopecia Mucinosa

Synonyms(2)

Research Excerpts

Context

Treatment

Research

Studies (58)

Drugs Studied (43)

Protein Targets (647)