Any 3beta-hydroxy-steroid that contains a double bond between positions 5 and 6.
| Member | Definition | Role |
|---|
| (20s)-20-hydroxycholesterol | An oxysterol that is cholesterol substituted by a hydroxy group at position 20. | 20-hydroxycholesterol |
| (22r)-22-hydroxycholesterol | An oxysterol that is the 22R-hydroxy derivative of cholesterol. | (22R)-22-hydroxycholesterol |
| 16-dehydropregnenolone | A 3beta-hydroxy-Delta(5)-steroid that is pregnenolone with a double bond between positions 16 and 17. | 16,17-didehydropregnenolone |
| 16-hydroxydehydroepiandrosterone | | 16alpha-hydroxydehydroepiandrosterone |
| 17-alpha-hydroxypregnenolone | A hydroxypregnenolone carrying an alpha-hydroxy group at position 17. | 17alpha-hydroxypregnenolone |
| 20,22-dihydroxycholesterol | An oxysterol that is cholesterol substituted by hydroxy groups at positions 20 and 22 (the 20R,22R-stereoisomer). | (20R,22R)-20,22-dihydroxycholesterol |
| 22-ketocholesterol | A 3beta-sterol that is cholesterol carrying an oxo group at position 22. | 22-ketocholesterol |
| 22s-hydroxycholesterol | An oxysterol that is the 22S-hydroxy derivative of cholesterol. | (22S)-22-hydroxycholesterol |
| 24-hydroxycholesterol | An oxysterol that is cholesterol which is substituted by a hydroxy group at position 24. | 24-hydroxycholesterol |
| 24-methylenecholesterol | A 3beta-sterol having the structure of cholesterol with a methylene group at C-24. | 24-methylenecholesterol |
| 24,25-epoxycholesterol | A 3beta-hydroxy-Delta(5)-steroid that is desmosterol in which the double bond at position 24-25 has been oxidised to the corresponding epoxide (the 24S diastereoisomer). It is an oxysterol agonist of the liver X receptor. | 24(S),25-epoxycholesterol |
| 3-hydroxy-5-cholestenoic acid | A steroid acid resulting from the oxidation of one of the terminal methyl groups of cholesterol to the corresponding aldehyde. | 3beta-hydroxycholest-5-en-26-oic acid |
| 7-aminocholesterol | A 3beta-sterol that is cholesterol substituted at position 7 by an amino group. | 7-aminocholesterol |
| 7-dehydrocholesterol | | cholesta-5,7-dien-3beta-ol |
| 7-hydroxydehydroepiandrosterone | An androstanoid that is dehydroepiandrosterone carrying an additional hydroxy substituent at the 7alpha-position. | 7alpha-hydroxydehydroepiandrosterone |
| 7-ketocholesterol | A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7. | 7-ketocholesterol |
| 7-oxodehydroepiandrosterone | A 3beta-hydroxy-Delta(5)-steroid that is dehydroepiandrosterone carrying an additional oxo group at position 7. | 7-ketodehydroepiandrosterone |
| abiraterone | A 3beta-sterol that is androsta-5,16-dien-3beta-ol substituted at position 17 by a 3-pyridyl group. Administered as the O-acetate, it is used for treatment of metastatic castrate-resistant prostate cancer. | abiraterone |
| androstenediol | A 3beta-hydroxy-Delta(5)-steroid that is 3beta-hydroxyandrost-5-ene carrying an additional hydroxy group at position 17beta. | androst-5-ene-3beta,17beta-diol |
| brassicasterol | An 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil. | brassicasterol |
| campesterol | | campesterol |
| cholest-5-en-3 beta,7 alpha-diol | The 7alpha-hydroxy derivative of cholesterol. | 7alpha-hydroxycholesterol |
| cholest-5-ene-3 beta,26-diol | An oxysterol that is cholesterol substituted at position 26 by a hydroxy group. | 26-hydroxycholesterol |
| dehydroepiandrosterone | An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands. | dehydroepiandrosterone |
| dehydroergosterol | A phytosterol consiting of ergostane having double bonds at the 5,6-, 7,8- 9,11- and 22,23-positions as well as a 3beta-hydroxy group. | dehydroergosterol |
| desmosterol | A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol. | desmosterol |
| ergosterol | A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group. | ergosterol |
| gamma-sitosterol | A member of the class of phytosterols that is poriferast-5-ene carrying a beta-hydroxy substituent at position 3. | clionasterol |
| hydroxysitosterol | A 3beta-hydroxy steroid that is sitosterol substituted by an additional alpha-hydroxy group at position 7. It has been isolated from the roots of Breynia fruticosa. | stigmast-5-ene-3beta,7alpha-diol |
| nuatigenin | | nuatigenin |
| pregnenolone | A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20. | pregnenolone |
| sitosterol, (3beta)-isomer | A member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. | sitosterol |
| solanidine | | solanidine |
| stigmasterol | A 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions. | stigmasterol |