Page last updated: 2024-09-27

Furcation Defects

Conditions in which a bifurcation or trifurcation of the molar tooth root becomes denuded as a result of periodontal disease. It may be followed by tooth mobility, temperature sensitivity, pain, and alveolar bone resorption.

Synonyms(1)

Synonym
Furcation Defects

Research Excerpts

Overview

ExcerptReference
"The treatment of furcation defects is a complex and difficult task that may compromise the success of periodontal therapy."( Deliberador, TM; Giovanini, AF; Lopes, TR; Mendes, RT; Storrer, CL; Zielak, JC, 2012)

Research

Studies (226)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's84 (37.17)12.5806
2000's72 (31.86)18.1394
2010's64 (28.32)28.8240
2020's6 (2.65)9.53
DrugIndicatedRelationship StrengthStudiesTrials
citric acid, anhydrous0medium112
lactic acid0medium2813
formaldehyde0low10
iodine0low10
melatonin0low10
niacinamide0low10
menthol0medium11
alendronate0medium84
aspirin0medium11
caffeine0low10
beta-glycerophosphoric acid0low10
eucalyptol0medium11
ciprofloxacin0medium11
erythrosine0low10
haloperidol0medium41
metformin0medium11
metronidazole0medium95
potassium iodide0low10
corticosterone0low10
thyroxine0low10
triiodothyronine0low10
bromodeoxyuridine0low20
edetic acid0medium92
methylene blue0low20
tributyl citrate0medium11
isoprene0low10
thymol0medium11
boric acid0low10
cyclohexanol0medium11
diphenhydramine hydrochloride0low10
benzoylarginine-2-naphthylamide0low10
limestone0low20
n-methylpyrrolidone0low10
benzoylarginine nitroanilide0medium33
durapatite0medium155
zinc oxide0medium11
silver0medium11
titanium0medium52
erbium0low10
calcium phosphate, dibasic, anhydrous0low10
calcium phosphate, monobasic, anhydrous0low10
tricalcium phosphate0medium202
calcium sulfate0medium123
ozone0low10
tricalcium silicate0low20
tetradecanoylphorbol acetate0low10
ornidazole0medium21
fluorides0low20
danazol0low10
azides0low10
amoxicillin0medium84
simvastatin0low20
atorvastatin0medium11
acemannan0low10
nicotine0low20
fibrinogen0low10
dihydrorhodamine 1230low10
fingolimod hydrochloride0low10
diphenylphosphorazidate0low10
polytrimethylene carbonate0low10
htr composite0medium22
calcium pyrophosphate0low10
olpadronic acid0low10
povidone-iodine0medium43
fibrin0medium63
elastin0low10
inositol 3-phosphate0low10
zithromax0low10
bromochloroacetic acid0low20
isomethyleugenol0low10
pyrophosphate0low10
osteoprotegerin0low10
dinoprostone0low10
bismuth0medium11
cysteine0low10
selenium0low10
chlorhexidine0medium105
amoxicillin-potassium clavulanate combination0medium32
mocetinostat0medium11
lipid a0low10
acid phosphatase0low40
cellulose0medium32
vendex0low10
chitosan0low20
sodium hypochlorite0low20
mannans0low10
interleukin-80medium11
methylcellulose0low10
tetracycline0medium176
minocycline0low20
transforming growth factor beta0medium121
chondroitin sulfates0low10
guanine0low10
pemetrexed0low10
alcian blue0low10
formocresol0medium11

Protein Targets (915)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0101
Farnesyl pyrophosphate synthase0202
Acetylcholinesterase0303
Hypoxanthine-guanine phosphoribosyltransferase0202
Farnesyl pyrophosphate synthase 0101
Farnesyl pyrophosphate synthase 0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, Beta-lactamase5005
Chain A, 2-oxoglutarate Oxygenase6006
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
AR protein250025
apical membrane antigen 1, AMA13003
estrogen nuclear receptor alpha340034
Beta-lactamase 0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)4004
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
DNA polymerase kappa isoform 18008
ATP-binding cassette sub-family C member 3014014
Multidrug resistance-associated protein 4014015
Bile salt export pump0101
Bile salt export pump016016
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Cytochrome P450 2C9 0505
Beta-lactamase0001
Kappa-type opioid receptor0102
Solute carrier family 15 member 10101
Solute carrier family 15 member 10101
Cytochrome P450 2J20505
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Canalicular multispecific organic anion transporter 1014014
Chain A, TYROSYL-DNA PHOSPHODIESTERASE8008
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 87007
thioredoxin reductase7007
GLS protein4004
aldehyde dehydrogenase 1 family, member A1100010
thyroid stimulating hormone receptor9009
hypothetical protein, conserved4004
cytochrome P450 family 3 subfamily A polypeptide 4140014
EWS/FLI fusion protein120012
glucocorticoid receptor [Homo sapiens]210021
retinoic acid nuclear receptor alpha variant 1250025
estrogen-related nuclear receptor alpha250025
cytochrome P450 2D6100010
glucocerebrosidase5005
peroxisome proliferator-activated receptor delta110011
Rac1 protein0011
IDH17007
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
euchromatic histone-lysine N-methyltransferase 2140014
Bloom syndrome protein isoform 14004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
muscarinic acetylcholine receptor M15005
lethal factor (plasmid)5005
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0101
Carbonic anhydrase 10707
Carbonic anhydrase 20707
Fatty acid-binding protein, liver0101
Integrin beta-33104
Myeloperoxidase0202
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb3104
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10202
Adenosine receptor A10405
Adenosine receptor A2a0305
Substance-P receptor0101
Prostaglandin G/H synthase 20404
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma100010
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-15218
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10314
Sigma non-opioid intracellular receptor 10213
Chain A, Cruzipain4004
RAR-related orphan receptor gamma210021
SMAD family member 27007
SMAD family member 37007
GLI family zinc finger 3210021
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)8008
nuclear receptor subfamily 1, group I, member 3150015
retinoid X nuclear receptor alpha170017
pregnane X nuclear receptor180018
peroxisome proliferator activated receptor gamma120012
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
caspase-35005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a160016
Caspase-72002
vitamin D3 receptor isoform VDRA8008
thyroid hormone receptor beta isoform a110011
caspase-32002
thyroid hormone receptor beta isoform 2220022
nuclear factor erythroid 2-related factor 2 isoform 1210021
geminin200020
Voltage-dependent calcium channel gamma-2 subunit110011
Solute carrier organic anion transporter family member 2B1 0001
3-hydroxy-3-methylglutaryl-coenzyme A reductase0404
Cellular tumor antigen p53190019
ATP-dependent translocase ABCB10405
Insulin receptor 0202
Glutamate receptor 2110011
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
Histone deacetylase 10303
Histone deacetylase 20303
Solute carrier organic anion transporter family member 1B30002
Histone deacetylase 60202
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Solute carrier organic anion transporter family member 1B10205
Carbonic anhydrase 40303
Carbonic anhydrase0303
Carbonic anhydrase 150202
Eyes absent homolog 20202
lamin isoform A-delta10120012
Beta-lactamase0101
Beta-lactamase0101
thyroid stimulating hormone receptor130013
pregnane X receptor4004
ATAD5 protein, partial5005
TDP1 protein200020
Microtubule-associated protein tau5005
progesterone receptor100010
bromodomain adjacent to zinc finger domain 2B4004
arylsulfatase A3003
nuclear receptor subfamily 1, group I, member 24004
cellular tumor antigen p53 isoform a4004
Nuclear hormone receptor family member daf-120011
chromobox protein homolog 1100010
nuclear factor erythroid 2-related factor 2 isoform 25005
serine/threonine-protein kinase mTOR isoform 13003
oxysterols receptor LXR-beta isoform 10011
peripheral myelin protein 226006
survival motor neuron protein isoform d4004
Thymidine kinase, cytosolic0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Spike glycoprotein8008
Thymidine kinase0001
Thymidylate kinase0101
ATPase family AAA domain-containing protein 57007
Ataxin-27007
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase7007
farnesoid X nuclear receptor170017
v-jun sarcoma virus 17 oncogene homolog (avian)150015
atrial natriuretic peptide receptor 1 precursor1001
DNA polymerase beta2002
nuclear receptor ROR-gamma isoform 14004
Potassium channel subfamily K member 20112
Glycogen phosphorylase, muscle form0101
Renin0101
Cholinesterase0202
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0101
Adenosine receptor A30303
Replicase polyprotein 1ab0101
Amine oxidase [flavin-containing] A0202
Amine oxidase [flavin-containing] B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A30101
Adenosine receptor A2a0214
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A10316
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0224
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Guanine deaminase0102
ATP-dependent phosphofructokinase6006
Chain A, JmjC domain-containing histone demethylation protein 3A4004
Chain A, BCL-2-RELATED PROTEIN A10011
Luciferase7007
acid sphingomyelinase1001
acetylcholinesterase7007
PAX80001
glp-1 receptor, partial6006
15-lipoxygenase, partial3003
hypoxia-inducible factor 1 alpha subunit7007
USP1 protein, partial3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
PINK12002
G9009
67.9K protein1001
Parkin2002
heat shock protein 900011
calcineurin A1, putative0011
aryl hydrocarbon receptor140014
activating transcription factor 67007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
Histone H2A.x9009
cytochrome P450 2D6 isoform 13003
hepatocyte nuclear factor 4-alpha isoform 20202
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor3003
perilipin-50202
perilipin-10202
potassium voltage-gated channel subfamily H member 2 isoform d3003
transcriptional regulator ERG isoform 31001
heat shock protein beta-17007
huntingtin isoform 22002
importin subunit beta-1 isoform 11001
mitogen-activated protein kinase 18008
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 11001
flap endonuclease 12002
protein AF-9 isoform a0002
snurportin-11001
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0202
cytochrome P450 3A4 isoform 15005
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0002
bcl-2-like protein 11 isoform 10011
Gamma-aminobutyric acid receptor subunit pi5117
Synaptojanin-20101
Solute carrier family 22 member 20304
Solute carrier family 22 member 1 0507
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
Synaptojanin-10101
Solute carrier family 22 member 30202
Glutathione reductase, mitochondrial0204
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 9009
72 kDa type IV collagenase0202
Matrix metalloproteinase-90202
Gamma-aminobutyric acid receptor subunit beta-15117
Gamma-aminobutyric acid receptor subunit delta5117
Gamma-aminobutyric acid receptor subunit gamma-25117
Gamma-aminobutyric acid receptor subunit alpha-55117
Gamma-aminobutyric acid receptor subunit alpha-35117
Gamma-aminobutyric acid receptor subunit gamma-15117
Gamma-aminobutyric acid receptor subunit alpha-25117
Gamma-aminobutyric acid receptor subunit alpha-45117
Gamma-aminobutyric acid receptor subunit gamma-35117
Trypanothione reductase0101
Gamma-aminobutyric acid receptor subunit alpha-65117
Alpha-synuclein3104
Histamine H2 receptor5006
Gamma-aminobutyric acid receptor subunit beta-35117
Gamma-aminobutyric acid receptor subunit beta-25117
TAR DNA-binding protein 438008
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 41001
GABA theta subunit5117
Inositol hexakisphosphate kinase 19009
Multidrug and toxin extrusion protein 10202
Gamma-aminobutyric acid receptor subunit epsilon5117
Spermine oxidase0101
cytochrome P450 2C9, partial9009
Cytochrome P450 1A20404
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Cytochrome P450 3A40517
DNA gyrase subunit B0102
DNA gyrase subunit A0103
DNA gyrase subunit B0103
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
Cytochrome P450 2D60303
DNA topoisomerase 2-alpha0104
DNA gyrase subunit A0102
Cytochrome P450 2C190202
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Potassium voltage-gated channel subfamily H member 20607
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Protein-arginine deiminase type-40505
NFKB1 protein, partial2002
GALC protein1001
Thrombopoietin2002
nonstructural protein 12002
Solute carrier family 22 member 30101
Sex hormone-binding globulin0022
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0011
Androgen receptor0303
C-8 sterol isomerase0202
Solute carrier organic anion transporter family member 1A10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Solute carrier family 22 member 10304
Solute carrier family 22 member 20303
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Rap guanine nucleotide exchange factor 32002
Estrogen receptor0202
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Aldo-keto reductase family 1 member B10404
Alpha-2A adrenergic receptor0404
Beta-3 adrenergic receptor0202
Alpha-1B adrenergic receptor0606
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
Muscarinic acetylcholine receptor M30303
Glycine receptor subunit beta0202
Substance-K receptor0202
D(1A) dopamine receptor0405
Glycine receptor subunit alpha-20202
Sodium-dependent noradrenaline transporter 0415
Glycine receptor subunit alpha-30202
5-hydroxytryptamine receptor 2A0404
Sodium-dependent serotonin transporter0404
Mu-type opioid receptor0415
D(3) dopamine receptor0417
Kappa-type opioid receptor0202
Alpha-1A adrenergic receptor0707
Sodium-dependent dopamine transporter 0202
regulator of G-protein signaling 45005
prostaglandin E2 receptor EP2 subtype1001
Solute carrier organic anion transporter family member 1A50003
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 60001
Solute carrier family 22 member 70001
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 80002
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110002
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70002
endonuclease IV1001
peripheral myelin protein 22 isoform 13003
eyes absent homolog 2 isoform a2002
Inositol monophosphatase 13003
Amyloid-beta precursor protein0202
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Genome polyprotein 0112
chaperonin-containing TCP-1 beta subunit homolog2002
Fumarate hydratase4004
thioredoxin glutathione reductase2002
polyprotein4004
thyrotropin-releasing hormone receptor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
histone acetyltransferase KAT2A isoform 14004
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
streptokinase A precursor0022
Estrogen receptor0011
5-hydroxytryptamine receptor 3A0202
Estrogen receptor beta0011
Transient receptor potential cation channel subfamily M member 80125
Ubiquitin carboxyl-terminal hydrolase isozyme L30101
Ubiquitin carboxyl-terminal hydrolase isozyme L10101
Sphingosine 1-phosphate receptor 10011
RCG53912, isoform CRA_a 0001
Sphingosine kinase 1 0001
Sphingosine kinase 20001
Sphingosine kinase 10001
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Adenylate cyclase type 1 0101
D(1A) dopamine receptor2002
transient receptor potential cation channel subfamily V member 11001
Cocaine esterase0101
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
UDP-glucuronosyltransferase 1A90102
Voltage-dependent L-type calcium channel subunit alpha-1F0202
5-hydroxytryptamine receptor 40202
Albumin0011
Major prion protein0011
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0011
Integrin beta-10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M10303
Muscarinic acetylcholine receptor M30303
Muscarinic acetylcholine receptor M40404
5-hydroxytryptamine receptor 1A0202
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M50303
Muscarinic acetylcholine receptor M50202
Beta-2 adrenergic receptor0202
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M10202
Angiotensin-converting enzyme0101
Integrin alpha-40202
D(2) dopamine receptor0215
5-hydroxytryptamine receptor 2A0202
Carbonyl reductase [NADPH] 10001
UDP-glucuronosyltransferase 2B70102
Beta-1 adrenergic receptor0202
D0202
D(3) dopamine receptor0202
5-hydroxytryptamine receptor 1A0202
Alpha-2B adrenergic receptor0101
D(2) dopamine receptor0202
D(4) dopamine receptor0215
D(1B) dopamine receptor0203
Adenylate cyclase type 30101
Alpha-2C adrenergic receptor0101
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0404
Sodium-dependent dopamine transporter0101
5-hydroxytryptamine receptor 3A0101
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
D(1B) dopamine receptor0202
Beta-3 adrenergic receptor0101
Adenylate cyclase type 20101
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
Histamine H1 receptor0202
Sodium-dependent serotonin transporter0101
5-hydroxytryptamine receptor 7 0101
Delta-type opioid receptor0202
Mu-type opioid receptor0303
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Kappa-type opioid receptor0101
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 2A0101
Histamine H1 receptor0202
Alpha-1B adrenergic receptor0101
Glutamate receptor ionotropic, NMDA 1 0101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
Adenylate cyclase type 80101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 2A0101
D(1A) dopamine receptor1102
5-hydroxytryptamine receptor 60101
5-hydroxytryptamine receptor 70101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
D(2) dopamine receptor0202
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
5-hydroxytryptamine receptor 40101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Sigma intracellular receptor 20101
Sigma non-opioid intracellular receptor 10213
Zinc finger protein 6640101
Glutamate receptor ionotropic, NMDA 2D0101
Vesicular acetylcholine transporter0101
Transporter0101
Cholecystokinin receptor type A0101
Protease 0202
Adenylyl cyclase 7 0101
Glutamate receptor ionotropic, NMDA 3B0101
D0101
Sodium channel protein type 2 subunit alpha0101
Transient receptor potential cation channel subfamily V member 40101
Sodium channel protein type 3 subunit alpha0101
Glutamate receptor ionotropic, NMDA 3A0101
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Transient receptor potential cation channel subfamily V member 20101
Sodium channel protein type 10 subunit alpha0101
histone deacetylase 9 isoform 33003
ClpP1001
ras-related protein Rab-9A1001
M-phase phosphoprotein 81001
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Cytochrome P450 2C11 0101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0101
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Carboxylic ester hydrolase 0101
Histamine H3 receptor0101
Transient receptor potential cation channel subfamily A member 10033
Secreted chorismate mutase0202
Transient receptor potential cation channel subfamily A member 10022
Transient receptor potential cation channel subfamily M member 80123
Chain A, Ferritin light chain3003
Dihydrofolate reductase0303
Dipeptidyl peptidase 40101
Chain E, Fibrin beta chain0101
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
PPM1D protein3003
TSHR protein1001
Apoptotic peptidase activating factor 10101
Smad33003
isocitrate dehydrogenase 1, partial1001
luciferase1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Vpr1001
muscleblind-like protein 1 isoform 13003
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
neuropeptide S receptor isoform A2002
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0314
Cruzipain0101
Guanine nucleotide-binding protein G1001
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
Thioredoxin reductase 0101
Flavodoxin0001
Lanosterol 14-alpha demethylase0101
Albumin0011
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0202
Protein mono-ADP-ribosyltransferase PARP150202
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Leukotriene A-4 hydrolase0101
Histone deacetylase 40101
Histone deacetylase 70101
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
Bromodomain-containing protein 40101
Cannabinoid receptor 10101
CREB-binding protein0101
Bromodomain adjacent to zinc finger domain protein 2B0101
Chain A, NAD-dependent deacetylase0101
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
NAD-dependent protein deacetylase 0101
5-hydroxytryptamine receptor 3E0101
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3B0101
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-30225
Acetylcholine receptor subunit gamma0213
Neuronal acetylcholine receptor subunit alpha-40101
Neuronal acetylcholine receptor subunit alpha-40225
Acetylcholine receptor subunit beta0213
Cytochrome P450 2A60213
Neuronal acetylcholine receptor subunit alpha-20225
Neuronal acetylcholine receptor subunit beta-20225
Neuronal acetylcholine receptor subunit beta-30225
Neuronal acetylcholine receptor subunit beta-40225
Translocator protein0101
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-50225
Cytochrome P450 2A50101
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Delta-type opioid receptor0101
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-60225
Neuronal acetylcholine receptor subunit alpha-90225
Neuronal acetylcholine receptor subunit alpha-40213
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Mu-type opioid receptor0101
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Neuronal acetylcholine receptor subunit alpha-70225
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
5-hydroxytryptamine receptor 3D0101
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-100225
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Transporter0113
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Thymidylate synthase 0101
Thymidylate synthase 0101
tyrosine-protein kinase Yes1001
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Thymidylate synthase0202
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0101
Folate receptor beta0101
Folate receptor alpha0101
Dihydrofolate reductase0101
Trifunctional purine biosynthetic protein adenosine-30202
Bifunctional purine biosynthesis protein ATIC0202
Serine hydroxymethyltransferase, cytosolic0112
Reduced folate transporter0101
Thymidylate synthase 0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trifunctional purine biosynthetic protein adenosine-30101
Proton-coupled folate transporter0203
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 90101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
photoreceptor-specific nuclear receptor0101
serine/threonine-protein kinase PLK12002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Nuclear receptor subfamily 4 group A member 20011
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
Tetracycline resistance protein, class B0001
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
P2Y purinoceptor 120101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Protein kinase C alpha type0112
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain B, Odorant-binding Protein0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Chain A, ODORANT-BINDING PROTEIN0101
Acetylcholinesterase0101
Polyphenol oxidase 20101
Cholinesterase0101
Heat sensitive channel TRPV30011
Transient receptor potential cation channel subfamily A member 10112
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Solute carrier organic anion transporter family member 1A40103
Nuclear receptor subfamily 1 group I member 20011
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Prothrombin0011
Androgen receptor0101
Gamma-aminobutyric acid receptor subunit alpha-10101
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Solute carrier organic anion transporter family member 4C10001
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Solute carrier organic anion transporter family member 1C10101
Gamma-aminobutyric acid receptor subunit theta0101
twin arginine protein translocation system - TatA protein0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]