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hydrate

An addition compound that contains water in weak chemical combination with another compound.

ChEBI ID: 35505

Members (33)

MemberDefinitionRole
alendronate sodiumA hydride that is the trihydrate of alendronate sodiumalendronate sodium trihydrate
amidotrizoic acid dihydrateThe dihydrate form of amidotrizoic acid. Both the dihydrate and the anhydrous form are used as X-ray contrast media.amidotrizoic acid dihydrate
amiloride hydrochlorideA hydrate that is the dihydrate of amiloride hydrochloride.amiloride hydrochloride dihydrate
ampicillin trihydrateampicillin trihydrate
calcipotrieneA hydrate that is the monohydrate form of calcipotriol. It is used in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.calcipotriol hydrate
calcium phosphate, dibasic, dihydratecalcium hydrogenphosphate dihydrate
calcium sulfate dihydratecalcium sulfate dihydrate
carbidopaThe hydrate of 3-(3,4-dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa.carbidopa
catechinThe monohydrate of (+)-catechin.(+)-catechin monohydrate
cetylpyridinium chloridecetylpyridinium chloride monohydrate
cordiumThe hydrochloride monohydrate of bepridril.bepridil hydrochloride monohydrate
cyclophosphamideThe monohydrate of cyclophosphamide.cyclophosphamide hydrate
dextromethorphan hydrobromideThe hydrobromide and monohydrate of the antitussive drug dextromethorphan.dextromethorphan hydrobromide
dicloxacillin sodiumdicloxacillin sodium monohydrate
docetaxelThe trihydrate form of docetaxel. It is used for the treatment of breast, ovarian, and non-small cell lung cancer, and with prednisone or prednisolone in hormone-refractory metastatic prostate cancer.docetaxel trihydrate
eflornithine hydrochlorideThe hydrochloride and hydrate of the trypanocidal drug eflornithine.eflornithine hydrochloride monohydrate
fenoprofen calciumThe dihydrate form of the calcium salt of fenoprofen. A non-steroidal anti-inflammatory drug, it is used for the management of mild to moderate pain and for the relief of pain and inflammation associated with disorders such as arthritis. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.fenoprofen calcium
gadodiamide hydrateThe hydrate of gadodiamide.gadodiamide hydrate
lidocaine hydrochlorideThe monohydrate form of lidocaine hydrochloride.lidocaine hydrochloride monohydrate
lisinoprillisinopril dihydrate
manganese chlorideA hydrate that is the tetrahydrate form of manganese(II) chloride.manganese(II) chloride tetrahydrate
meclofenamate sodium anhydrousA hydrate that is the monohydrate of the sodium salt of meclofenamic acid. It is used for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.sodium meclofenamate monohydrate
mercaptopurinemercaptopurine hydrate
methicillin sodiummethicillin sodium monohydrate
methixene hydrochloridemethixene hydrochloride
morphine sulfatemorphine sulfate pentahydrate
nafcillin sodiumnafcillin sodium monohydrate
quinine sulfatequinine sulfate dihydrate
sodium bromfenacThe sesquihydrate of the sodium salt of bromfenac. It is used for the management of ocular pain and treatment of postoperative inflammation in patients who have undergone cataract extraction.bromfenac sodium salt sesquihydrate
struviteA hydrate that is the hexahydrate form of ammonium magnesium phosphate. It is a constituent of urinary calculi.ammonium magnesium phosphate hexahydrate
sulfacetamide sodiumAn organic sodium salt that is the monohydrate form of sulfacetamide sodium.sulfacetamide sodium
tolmetin sodiumAn organic sodium salt that is the dihydrate form of tolmetin sodium. Used as a nonselective nonsteroidal anti-inflammatory drug.tolmetin sodium dihydrate
ziprasidone hydrochlorideThe hydrochloride hydrate salt of ziprasidone.ziprasidone hydrochloride hydrate

Research

Studies (3,124)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990241 (7.71)18.7374
1990's511 (16.36)18.2507
2000's787 (25.19)29.6817
2010's1,064 (34.06)24.3611
2020's521 (16.68)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials368 (10.45%)5.53%
Reviews288 (8.17%)6.00%
Case Studies242 (6.87%)4.05%
Observational8 (0.23%)0.25%
Other2,617 (74.28%)84.16%