Page last updated: 2024-08-05 11:20:10

benzenedicarboxamide

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ChEBI ID: 38800

Members (7)

MemberDefinitionRole
iobitridolA benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a 3-hydroxy-2-(hydroxymethyl)propanimido at position 5.iobitridol
iohexolA benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.iohexol
iomeprolA benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a glycoloyl(methyl)amino group at the 5-position.iomeprol
iopamidolA benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and a (2S)-2-hydroxypropanamido group at the 5-position.iopamidol
ioxaglateA benzenedicarboxamide compound having N-substituted carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an acetyl(methyl)amino group at the 5-position.ioxaglic acid
terephthalamideterephthalamide
tolvaptanA benzazepine derivative incorporating a benzenedicarboxamide function whch is a selective vasopressin V2 receptor antagonist used to treat euvolemic and hypervolemic hyponatremia. It is also used in the treatment of rapidly progressing autosomal dominant polycystic kidney disease to slow the rate of cyst development and renal insufficiency. Tolvaptan is a racemate consisting of a 1:1 mixture of 5R and 5S stereomers.tolvaptan

Research

Studies (7,996)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,056 (13.21)18.7374
1990's1,578 (19.73)18.2507
2000's1,659 (20.75)29.6817
2010's3,164 (39.57)24.3611
2020's539 (6.74)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,730 (15.83%)5.53%
Reviews389 (3.56%)6.00%
Case Studies941 (8.61%)4.05%
Observational85 (0.78%)0.25%
Other7,784 (71.22%)84.16%