Page last updated: 2024-08-05 11:12:39

phenothiazines

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ChEBI ID: 38093

Members (73)

MemberDefinitionRole
(4-methylphenyl)-(10-phenothiazinyl)methanone(4-methylphenyl)-(10-phenothiazinyl)methanone
1-(1-benzotriazolyl)-3-(10-phenothiazinyl)-2-propanol1-(1-benzotriazolyl)-3-(10-phenothiazinyl)-2-propanol
1-(10-methyl-2-phenothiazinyl)ethanone1-(10-methyl-2-phenothiazinyl)ethanone
1-(10h-phenothiazin-2-yl)ethanone1-(10H-phenothiazin-2-yl)ethanone
1-(2-chloro-10-phenothiazinyl)-2-[(1-methyl-5-tetrazolyl)thio]ethanone1-(2-chloro-10-phenothiazinyl)-2-[(1-methyl-5-tetrazolyl)thio]ethanone
10-methyl-3-phenothiazinamine10-methyl-3-phenothiazinamine
10H-phenothiazine 5-oxide10H-phenothiazine 5-oxide
2-chloro-N-[1-[oxo(10-phenothiazinyl)methyl]-4-piperidinyl]benzamide2-chloro-N-[1-[oxo(10-phenothiazinyl)methyl]-4-piperidinyl]benzamide
3-[4-(2-hydroxyethyl)-1-piperazinyl]-1-[2-(trifluoromethyl)-10-phenothiazinyl]-1-propanone3-[4-(2-hydroxyethyl)-1-piperazinyl]-1-[2-(trifluoromethyl)-10-phenothiazinyl]-1-propanone
7-hydroxychlorpromazine8-chloro-10-[3-(dimethylamino)propyl]-3-phenothiazinol
acepromazineA member of the class of phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10.acepromazine
acetophenazineA member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the nitogen atom and an acetyl group at position 2.acetophenazine
butaperazinebutaperazine
chlorfenethazine2-(2-chloro-10-phenothiazinyl)-N,N-dimethylethanamine
chlorproethazinechlorproethazine
chlorpromazineA substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.chlorpromazine
chlorpromazine hydrochlorideThe hydrochloride salt of chlorpromazine.chlorpromazine hydrochloride
chlorpromazine n-oxideAn organochlorine compound that is chlorpromazine in which the acyclic tertiary amino group has been converted into the corresponding N-oxide.chlorpromazine N-oxide
cyamemazinecyamemazine
darunavir ethanolate2-[[4-ethyl-5-(2-furanyl)-1,2,4-triazol-3-yl]thio]-1-(10-phenothiazinyl)ethanone
didemethylchlorpromazine3-(2-chloro-10-phenothiazinyl)-1-propanamine
diethazinediethazine
dixyrazinedixyrazine
ethacizineethacizine
fenethazinefenethazine
fenoverinefenoverine
fluoracizinefluacizine
fluphenazineA member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.fluphenazine
fluphenazine depotThe prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia.fluphenazine decanoate
fluphenazine enanthateFluphenazine enanthate
fluphenazine hydrochlorideFluphenazine hydrochloride
fonazinedimetotiazine
hydromethylthionineA member of the class of phenothiazines that is 10H-phenothiazine in which the ring hydrogens at positions 3 and 7 have been replaced by dimethylamino groups.leucomethylene blue
mepazinepecazine
mequitazineMequitazine
mesoridazineA phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group.mesoridazine
methdilazineA phenothiazine substituted on nitrogen by a (1-methylpyrrolidin-3-yl)methyl group; a first-generation antihistamine with anticholinergic properties.methdilazine
methopromazinemethopromazine
methotrimeprazineA member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively.methotrimeprazine
methotrimeprazine sulfoxide10-[3-(dimethylamino)-2-methylpropyl]-2-methoxy-5lambda4-phenothiazin-5-one
metiazinic acidPhenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.metiazinic acid
metofenazateA phenothiazine derivative having a chloro subsitituent at the 2-position and a 4-substituted 3-(piperazin-1-yl)propyl group at the N-10 position.metofenazate
metopimazinemetopimazine
moricizineA phenothiazine substituted on the nitrogen by a 3-(morpholin-4-yl)propanoyl group, and at position 2 by an (ethoxycarbonyl)amino group.moricizine
n-methylphenothiazine10-methylphenothiazine
norchlorpromazine3-(2-chloro-10-phenothiazinyl)-N-methyl-1-propanamine
opromazine3-(2-chloro-5-oxo-10-phenothiazinyl)-N,N-dimethyl-1-propanamine
oxomemazineoxomemazine
perazineA phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position.perazine
periciazineA member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-(4-hydroxypiperidin-1-yl)propyl group at the nitrogen atom and a carbonitrile group at position 2. Periciazine is a first generation antipsychotic.periciazine
perphenazineA phenothiazine derivative in which the phenothiazine tricycle carries a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at N-10.perphenazine
perphenazine decanoateperphenazine decanoate
piperacetazine1-[10-[3-[4-(2-hydroxyethyl)-1-piperidinyl]propyl]-2-phenothiazinyl]ethanone
pipothiazine palmitatepipotiazine palmitate
prochlorperazineA member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.prochlorperazine
profenamineA member of the class of phenothiazines that is phenothiazine in which the hydrogen attached to the nitrogen is substituted by a 2-(diethylamino)propyl group. An antimuscarinic, it is used as the hydrochloride for the symptomatic treatment of Parkinson's disease.profenamine
promazineA phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position.promazine
promethazineA tertiary amine that is a substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropan-2-amine moiety.promethazine
promethazine sulfoxidePromethazine sulfoxide
propiomazineA member of the class of phenothiazines that is 10H-phenothiazine substituted by a 2-(dimethylamino)propyl group at nitrogen atom and a propanoyl group at position 2.propiomazine
pyrathiazineparathiazine
sk&f 7172-a210-[3-[4-(2-chloroethyl)-1-piperazinyl]propyl]-2-(trifluoromethyl)phenothiazine
sulforidazinesulforidazine
thiazinamiumthiazinam
thiethylperazineA member of the class of phenothiazines that is perazine substituted by a ethylsulfanyl group at position 2.thiethylperazine
thiopropazateA phenothiazine derivative in which 10H-phenothiazine has a chloro subsitituent at the 2-position and a 3-[4-(2-acetoxyethyl)piperazin-1-yl]propyl group at N-10.thiopropazate
thioproperazineA phenothiazine derivative in which the phenothiazine tricycle has a dimethylaminosulfonyl substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at N-10.thioproperazine
thioproperazine mesylateThioproperazine mesilate
thioridazineA phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position.thioridazine
trifluoperazineA member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position.trifluoperazine
trifluoromethylphenothiazine2-(trifluoromethyl)-10H-phenothiazine
triflupromazineA member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(dimethylamino)propyl group at the N-10 position.triflupromazine
trimeprazineTrimeprazine

Research

Studies (29,432)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199022,087 (75.04)18.7374
1990's3,140 (10.67)18.2507
2000's2,095 (7.12)29.6817
2010's1,671 (5.68)24.3611
2020's439 (1.49)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials3,005 (7.86%)5.53%
Reviews1,211 (3.17%)6.00%
Case Studies2,241 (5.86%)4.05%
Observational25 (0.07%)0.25%
Other31,753 (83.05%)84.16%