A ketone that is 1,3-diphenylpropenone (benzylideneacetophenone), ArCH=CH(=O)Ar, and its derivatives formed by substitution.
| Member | Definition | Role |
|---|
| 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one | | 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one |
| 1-phenyl-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one | | 1-phenyl-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one |
| 2,4,2',4'-Tetrahydroxychalcone | | 2,4,2',4'-Tetrahydroxychalcone |
| 2'-hydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 2'. | 2'-hydroxychalcone |
| 2',3,4-trihydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2', 3 and 4. The precursor of 3',4'-dihydroxyaurone. | 2',3,4-trihydroxy-trans-chalcone |
| 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' and 4', a methoxy group at position 6' and methyl groups at positions 3' and 5'. Isolated from the buds of Cleistocalyx operculatus, it has been shown to exhibit inhibitory effects on the viral neuraminidases from two influenza viral strains, H1N1 and H9N2. | 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone |
| 2',4',6'-trihydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2', 4' and 6' respectively. | pinocembrin chalcone |
| 2',4',6'-Trihydroxydihydrochalcone | | 2',4',6'-Trihydroxydihydrochalcone |
| 2',5'-dihydroxychalcone | | 2',5'-Dihydroxychalcone |
| 2',6'-dihydroxy-4'-methoxychalcone | | Pinostrobin chalcone |
| 3-deoxysappanchalcone | A member of the class of chalcones that is isoliquiritigenin in which one of the hydroxy groups at position 2' is replaced by a methoxy group. | 2'-O-methylisoliquiritigenin |
| 3-hydroxyphloretin | | 3-Hydroxyphloretin |
| 3-o-methylbutein | | Homobutein |
| 4-chlorochalcone | A member of the class of chalcones that is trans-chalcone substituted by a chloro group at position 4. | 4-chlorochalcone |
| 4-hydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4. | 4-hydroxychalcone |
| 4-hydroxycordoin | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at position 4 and 2' and a (3-methylbut-2-en-1-yl)oxy group at position 4'. It has been isolated from Lonchocarpus neuroscapha. | 4-hydroxycordoin |
| 4-hydroxyderricin | | 4-Hydroxyderricin |
| 4-Methoxylonchocarpin | | 4-Methoxylonchocarpin |
| 4'-hydroxychalcone | A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4'. | 4'-hydroxychalcone |
| 4'-methoxychalcone | | 4'-Methoxychalcone |
| bavachalcone | | Bavachalcone |
| butein | A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'. | butein |
| calythropsin | | Calythropsin |
| cardamonin | | Cardamonin |
| Crotaoprostrin | | Crotaoprostrin |
| derricidin | | Derricidin |
| flavokawain a | | Flavokawain A |
| flavokawain b | A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy group at positions 2' and methoxy groups at positions 4' and 6'. Isolated from Piper methysticum and Piper rusbyi, it exhibits antileishmanial, anti-inflammatory and antineoplastic activities. | flavokawain B |
| flavokawain C | | flavokawain C |
| helichrysetin | | Helichrysetin |
| isobavachalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4' and a prenyl group at position 3'. | isobavachalcone |
| isobutrin | A member of the class of chalcones that is trans-chalcone substituted by beta-D-glucopyranosyloxy groups at positions 3 and 4' and hydroxy groups at positions 4 and 2' respectively. | isobutrin |
| isocordoin | | Isocordoin |
| isoliquiritigenin | A member of the class of chalcones that is trans-chalcone hydroxylated at C-2', -4 and -4'. | isoliquiritigenin |
| Isoliquiritigenin 4,4'-dimethyl ether | | Isoliquiritigenin 4,4'-dimethyl ether |
| isosalipurposide | A monosaccharide derivative that is trans-chalcone substituted by hydroxy groups at positions 4, 4' and 6 and a beta-D-glucopyranosyloxy group at position 2' respectively. | phlorizin chalcone |
| Kanzonol B | | Kanzonol B |
| licochalcone a | | Licochalcone A |
| licochalcone b | | Licochalcone B |
| linderol a | | (-)-Linderol A |
| Lonchocarpin | | Lonchocarpin |
| morachalcone a | | Morachalcone A |
| myrigalone b | | Myrigalon B |
| naringenin chalcone | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively. | 2',4,4',6'-tetrahydroxychalcone |
| okanin | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 3, 4, 2', 3', and 4' respectively. | okanin |
| perflubron | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2', 4', and 6' and a 3-methylbut-2-en-1-yl group at position 3'. | desmethylxanthohumol |
| sappanchalcone | A member of the class of chalcones that consists of trans-chalcone substituted by hydroxy groups at positions 3, 4 and 4' and a methoxy group at position 2'. Isolated from Caesalpinia sappan, it exhibits neuroprotective and cytoprotective activity. | sappanchalcone |
| sofalcone | A member of the class of chalcones that is benzene in which the hydrogens at positions 1,2 and 5 are replaced by carboxymethoxy, (1E)-1-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}-3-oxoprop-1-en-3-yl, and (3-methylbut-2-en-1-yl)oxy groups, respectively. It is a gastrointestinal drug currently used for treatment of gastritis and gastric ulcers in Japan and South Korea. | sofalcone |
| Uvangoletin | | Uvangoletin |
| Xanthoangelol D | | Xanthoangelol D |
| xanthohumol | A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. | xanthohumol |
| xanthohumol c | | Xanthohumol C |