tetracycline and Penile-Diseases

Twenty nine patients with genital fixed drug eruptions were studied during one year. In 15 the genitalia were exclusively affected, whereas the other 14 had cutaneous lesions in addition. It was striking that those whose lesions were exclusively genital reported for consultation much earlier. Drug history was the mainstay of diagnosis. Provocation tests with graded doses of the suspected drug(s) were undertaken in all cases. Tetracycline was the commonest causative drug, followed by oxyphenbutazone and acetylsalicylic acid.

Topics: Adolescent; Adult; Child; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Penile Diseases; Skin Tests; Skin Ulcer; Tetracycline; Vaginal Diseases; Vulvar Diseases

Fixed drug eruptions are a rarely reported complication of tetracycline therapy. For poorly understood reasons, the epithelium of the glans penis seems unusually susceptible to this type of reaction. We report 3 additional cases of balanitis secondary to orally administered tetracycline and suggest that there may not be cross sensitivity to doxycycline.

Topics: Adult; Aged; Balanitis; Drug Eruptions; Humans; Male; Middle Aged; Penile Diseases; Tetracycline

Gonococcal pharyngitis has been correlated with fellatio in both heterosexual females and homosexual males. This report describes another complication of fellatio, group A beta-eaemolytic streptococcal pyroderma on the penis after exposure to a male who probably had pharyngitis. the erythematous, purulent lesions should be cultured. After the organism has been identified, adequate treatment with either a long-acting parenteral penicillin or a 10-day course of oral penicillin is important in order to prevent the possible life-threatening complication of post-streptococcal glomerulonephritis.

Topics: Adult; Homosexuality; Humans; Male; Penile Diseases; Pyoderma; Sexually Transmitted Diseases; Streptococcal Infections; Tetracycline

The improved control over most infectious disease does not extend to venereal infections, and these now provide the major medical problem encountered in wartime. This factor should be recognized when staff and facilities are being provided for wartime medical services. Unique problems of management of both physical and psychological illness may result from promiscuity in a foreign land during war, and specialist venereologists are as necessary as surgeons and physicians.

Topics: Australia; Chancroid; Drug Resistance, Microbial; Humans; Male; Military Medicine; Penile Diseases; Seasons; Sexually Transmitted Diseases; Skin Ulcer; Streptomycin; Sulfisoxazole; Tetracycline; Urethritis; Vietnam; Warfare; Warts

Topics: Adolescent; Adult; Ampicillin; Biopsy; Coitus; Female; Genital Diseases, Female; Gonorrhea; Humans; Hydrocortisone; Lip; Lip Diseases; Lymphangitis; Male; Penile Diseases; Penis; Tetracycline; Urethritis; Vulva

Topics: Adult; Drug Eruptions; Humans; Male; Penile Diseases; Tetracycline

Topics: Adolescent; Adult; Humans; Male; Middle Aged; Penile Diseases; Tetracycline

Topics: Humans; Male; Penile Diseases; Tetracycline

Topics: Diagnosis, Differential; Granuloma Inguinale; Humans; Madagascar; Male; Penile Diseases; Tetracycline

Topics: Adult; Blister; Drug Eruptions; Humans; Male; Middle Aged; Penile Diseases; Tetracycline

Topics: Adult; Carcinoma, Squamous Cell; Diagnosis, Differential; Granuloma Inguinale; Humans; Male; Middle Aged; Penile Diseases; Staining and Labeling; Streptomycin; Tetracycline