extracellular space

Definition

Target type: cellularcomponent

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]

The extracellular space (ECS) is the space between cells in a multicellular organism. It is filled with a fluid called extracellular fluid (ECF), which is composed of water, ions, and various proteins. The ECS serves as a medium for cell communication, nutrient transport, and waste removal.

**Key components of the ECS include:**

* **Interstitial fluid (ISF):** This is the fluid that fills the spaces between cells. It is composed of water, dissolved salts, and other molecules.
* **Blood plasma:** This is the fluid portion of blood. It contains a high concentration of proteins, as well as other molecules such as glucose, amino acids, and hormones.
* **Lymph:** This is a fluid that circulates throughout the body, collecting excess fluid from the ISF and returning it to the bloodstream.

**The ECS plays a critical role in:**

* **Cell communication:** The ECS allows for the diffusion of signaling molecules, such as hormones and neurotransmitters, between cells.
* **Nutrient transport:** Nutrients from the bloodstream are transported to cells via the ECS.
* **Waste removal:** Waste products from cells are transported to the bloodstream via the ECS.
* **Structural support:** The ECS provides a scaffold for cells to attach to and maintain their shape.

**The ECS is also involved in:**

* **Inflammation:** The ECS is involved in the recruitment of immune cells to sites of injury or infection.
* **Wound healing:** The ECS is involved in the delivery of cells and nutrients to wounds.
* **Tissue development:** The ECS plays a role in the development and organization of tissues.

**The composition of the ECS can vary depending on the tissue or organ.** For example, the ECS in the brain is different from the ECS in the liver.

**The ECS is a complex and dynamic environment that is essential for the proper function of multicellular organisms.**'
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Proteins (368)

Compounds (5,714)