Blow Out Fracture

Fractures of the bones in the orbit, which include parts of the frontal, ethmoidal, lacrimal, and sphenoid bones and the maxilla and zygoma.

Synonym
Orbital Fracture
Orbital Fractures
Fractures, Blow-Out
Blow Out Fracture
Blow-Out Fractures

Excerpt	Reference
"Although orbital fractures are common, orbital cellulitis rarely develops following orbital fracture."	( Chien, HF; Shieh, JY; Wen, CY; Wu, CH, 2001)
"Orbital fractures are frequently accompanied by ocular injury."	( Read, RW; Sires, BS, 1998)
"Orbital fractures are common."	( Asleh, SA; Lavy, T, 2003)
"Nasoethmoid orbital fractures are perhaps the most complicated aspect of craniomaxillofacial trauma."	( Rice, DH; Young, PA, 2007)
"Orbital fractures are some of the more challenging injuries faced by the plastic surgeon."	( Banerji, S; Boyd, V; Cole, P; Hollier, LH, 2007)
"Orbital fractures are not considered an ophthalmologic emergency unless there is visual impairment or globe injury."	( Briganti, F; Brunese, L; Cappabianca, S; Caranci, F; Cicala, D; Fonio, P, 2012)
"Orbital fractures are some of the most challenging injuries the oral surgeon deals with on a daily basis."	( Ghali, GE; Palmieri, CF, 2012)
"Orbital fractures are injuries frequently related to traumas of the midface."	( Cetira Filho, EL; Mello, MJR; Rocha, SSD; Rodrigues, PHC; Sales, PHDH; Silva, LF, 2017)
"Orbital fractures are common."	( Ellis, MF; Purnell, CA; Vaca, EE, 2018)
"Orbital fractures are high prevalent and result in several complications such as diplopia, muscular entrapment, visual impairment, and enophthalmos."	( Carvalho, PHA; Gabrielli, MAC; Moura, LB; Pereira-Filho, VA, 2018)
"Orbital fractures are among the most frequent facial traumas."	( Battisti, A; Della Monaca, M; Di Giorgio, D; Fadda, M; Marchese, G; Priore, P; Terenzi, V; Valentini, V, 2022)
"Although orbital fractures are common, prediction of outcomes in orbital surgery can be quite challenging."	( Amundson, M; Bell, RB; Demirel, S; Dierks, E; Govind, A; Lee, K, 2023)

Excerpt	Reference
"Pure orbital fractures have the tendency to occur on medial wall and orbital floor; because these points are more fragile, the endoscopy can be utilized for accomplishing the task of repositioning the herniated content, as well as serving as an additional tool, helping to view the orbital defects through a transantral approach."	( Bonardi, JP; Dallazen, E; Hochuli-Vieira, E; Martins, TH; Pereira-Stabile, CL; Stabile, GA, 2017)

Excerpt	Reference
"The location of the orbital fracture affects the enophthalmos, in our group of patients the largest incidence occurred in the fracture located in the orbital floor combined with medial wall."	( Gontarz, M; Koryczan, P; Wyszyńska-Pawelec, G; Zapała, J, 2020)

Excerpt	Reference
"One hundred forty-four orbital fractures treated between 1982 and 1987 were examined with special attention to the specific anatomic architecture and biomechanical aspects of the craniofacial skeleton."	( Wanyura, H, 1998)
"The goals of reconstruction when treating orbital fractures include restoration of internal wall continuity and provision of support to the orbital contents."	( Oliver, AJ, 2000)
"Treating orbital fractures under nasal endoscopic surgery has advantages such as no incision on face, less damage, clear view and easy recheck after operation."	( Hu, Y; Liu, W; Song, W; Wang, G; Wang, L; Xie, W, 2001)
"Twelve patients with orbital fractures were treated using individually preformed titanium implants."	( Gutwald, R; Metzger, MC; Schmelzeisen, R; Schön, R; Weyer, N; Zizelmann, C, 2007)
"This study consisted of 21 cases with orbital fractures treated at the Hospital of Stomatology, Sichuan University, China, between July 2002 and June 2006."	( Li, X; Lin, Y; Liu, L; Long, J; Tang, W; Tian, W; Wang, H; Wang, S; Xiao, J; Zheng, X, 2008)
"Treatment of zygomatic-orbital fractures with small local incisions is minimally invasive and the facial appearance and function can be recovered significantly with few complications."	( Dai, JH; Wang, SY; Yang, J, 2009)
"In this study, 588 cranio-orbital fractures following blunt trauma were evaluated retrospectively with regard to the anatomical site and surgical treatment."	( Atar, EK; Emel, E; Gocmen-Mas, N; Karabekir, HS; Karacayli, U; Koymen, R; Ozkan, N, 2012)
"Delay of the treatment of orbital fractures impacts the final result."	( Ghali, GE; Palmieri, CF, 2012)
"Next, ten cases for delayed surgical treatment of orbital fracture were included into this study (7 males, 3 females)."	( Kozakiewicz, M, 2014)
"The objectives of surgical treatment for orbital fracture are to return soft tissue to its original position as well as reduce and fix the bone fragments properly."	( Jo, EJ; Kim, JH; Yang, HJ, 2015)
"Surgical treatment of open orbital fractures with simultaneous repair of orbital fracture and soft tissue within 48 hours after trauma could correct enophthalmos, hypoglobus and eye movement function effectively and improve periorbital aesthetics."	( Dong, S; Hu, JY; Lu, W; Song, LY; Sun, H; Wu, PS, 2016)
"The best treatment of pediatric orbital fractures is debated and different strategies are proposed in the literature."	( Baj, A; Beltramini, GA; Giannì, AB; Laganà, FC; Segna, E, 2016)
"Patients with isolated orbital fractures, treated by the Oral and Maxillofacial Surgery Department in Auckland from 2010-2015, were reviewed."	( Anand, L; Sealey, C, 2017)
"Treatment of orbital fractures involves restoration of lost bone anatomy and orbital volume."	( Costa Filho, JZ; Costa, PJC; de Gauw, JH; Moreira, RT; Ribeiro Júnior, PD, 2018)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	162 (12.88)	23.3326
1990's	221 (17.57)	12.5806
2000's	265 (21.07)	18.1394
2010's	434 (34.50)	28.8240
2020's	176 (13.99)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	4	0
lactic acid	medium	21	1
formaldehyde	low	3	0
glycolic acid	low	1	0
dalteparin	low	1	0
methanol	low	11	0
nickel	low	4	0
acetaminophen	medium	1	1
acetazolamide	low	3	0
chlorpromazine	low	1	0
gentamicin	low	1	0
glyphosate	low	1	0
haloperidol	low	1	0
lidocaine	low	2	0
iodixanol	low	1	0
2-propanol	low	7	0
lorazepam	low	1	0
meperidine	low	1	0
ofloxacin	low	1	0
promethazine	low	1	0
saccharin	low	1	0
tetracaine	low	1	0
urethane	low	1	0
prednisolone	low	2	0
prednisone	medium	3	1
chloramphenicol	low	2	0
cephalothin	low	1	0
mannitol	low	1	0
ethylene	low	2	0
ethylene oxide	low	1	0
isoprene	low	5	0
methylmethacrylate	low	3	0
methylprednisolone	medium	10	1
dilactide	low	2	0
caprolactam	low	1	0
nafcillin	low	1	0
glycopyrrolate	low	2	0
durapatite	medium	27	3
enbucrilate	low	1	0
tantalum	low	2	0
technetium	low	1	0
titanium	medium	162	9
gold	low	1	0
phosphoric acid, trisodium salt	low	1	0
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	7	0
calcium sulfate	low	1	0
carticaine	low	1	0
propiconazole	medium	985	15
paroxetine	low	1	0
fomesafen	low	3	0
triazoles	low	2	0
voriconazole	low	1	0
ethyl 2-cyanoacrylate	low	1	0
fibrinogen	low	5	0
levofloxacin	low	1	0
terephthalamidine	low	1	0
calcium pyrophosphate	low	1	0
atropine	low	2	0
povidone-iodine	low	1	0
fibrin	low	1	0
glucosamine	low	1	0
inositol 3-phosphate	low	3	0
cocaine	low	1	0
posaconazole	low	1	0
phenylephrine hydrochloride	medium	67	1
oxycodone	medium	2	1
deamino arginine vasopressin	low	1	0
amoxicillin-potassium clavulanate combination	medium	4	2
scopolamine hydrobromide	low	1	0
jaw	low	2	0
bucladesine	low	1	0
tetracycline	low	1	0
warfarin	low	3	0
transforming growth factor beta	low	1	0
rome	low	2	0
agar	low	1	0
orabase	low	1	0
exudates	low	1	0
acyclovir	low	1	0
eye	low	36	0

Protein Targets (868)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
RAR-related orphan receptor gamma	18	0	0	18
GLI family zinc finger 3	19	0	0	19
AR protein	22	0	0	22
aldehyde dehydrogenase 1 family, member A1	12	0	0	12
retinoic acid nuclear receptor alpha variant 1	20	0	0	20
retinoid X nuclear receptor alpha	12	0	0	12
estrogen nuclear receptor alpha	29	0	0	29
peroxisome proliferator-activated receptor delta	7	0	0	7
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
activating transcription factor 6	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	10	0	0	10
Histone H2A.x	8	0	0	8
thyroid hormone receptor beta isoform a	5	0	0	5
heat shock protein beta-1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	17	0	0	17
lamin isoform A-delta10	10	0	0	10
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Glutamate receptor 2	6	0	0	6
ATAD5 protein, partial	6	0	0	6
GLS protein	6	0	0	6
Microtubule-associated protein tau	5	0	0	5
Smad3	3	0	0	3
thyroid stimulating hormone receptor	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	12	0	0	12
progesterone receptor	13	0	0	13
EWS/FLI fusion protein	9	0	0	9
estrogen-related nuclear receptor alpha	21	0	0	21
peroxisome proliferator activated receptor gamma	10	0	0	10
aryl hydrocarbon receptor	6	0	0	6
chromobox protein homolog 1	7	0	0	7
thyroid hormone receptor beta isoform 2	13	0	0	13
peripheral myelin protein 22	6	0	0	6
cytochrome P450 3A4 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	4	2	0	7
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	16
Solute carrier family 22 member 6	0	4	0	5
Carbonic anhydrase 12	0	6	1	10
UDP-glucuronosyltransferase 1A9	0	1	0	3
Bile salt export pump	0	5	0	5
Bile salt export pump	0	23	0	23
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	9	1	15
Carbonic anhydrase 2	0	9	2	15
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	1	1	3
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 3	0	6	1	10
Cytochrome P450 3A4	0	10	1	12
Cytochrome P450 2D6	0	5	1	6
Cytochrome P450 2C9	0	9	0	9
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	2	0	7
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	4	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	4	2	0	7
UDP-glucuronosyltransferase 1-6	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	4	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	4	2	0	7
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	8	1	11
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 6	0	6	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	4	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	4	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	4	2	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	4	2	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	4	2	0	7
Carbonic anhydrase 5A, mitochondrial	0	7	1	11
Prostaglandin G/H synthase 2	0	2	0	3
Carbonic anhydrase 7	0	6	1	9
Nuclear receptor ROR-gamma	2	0	0	2
Cytochrome P450 2J2	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	4	2	0	7
Gamma-aminobutyric acid receptor subunit beta-3	4	2	0	7
Gamma-aminobutyric acid receptor subunit beta-2	4	2	0	7
Carbonic anhydrase 9	0	8	1	12
GABA theta subunit	4	2	0	7
Canalicular multispecific organic anion transporter 1	0	15	0	15
Carbonic anhydrase 15	0	4	0	5
Carbonic anhydrase 13	0	5	0	7
Gamma-aminobutyric acid receptor subunit epsilon	4	2	0	7
Carbonic anhydrase 14	0	6	1	10
Carbonic anhydrase 5B, mitochondrial	0	7	1	11
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	5	0	0	5
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	4	0	0	4
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	3	0	3
thioredoxin reductase	11	0	0	11
GALC protein	2	0	0	2
cytochrome P450 family 3 subfamily A polypeptide 4	12	0	0	12
glucocorticoid receptor [Homo sapiens]	21	0	0	21
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
arylsulfatase A	5	0	0	5
Carbonic anhydrase	0	3	0	3
euchromatic histone-lysine N-methyltransferase 2	13	0	0	13
Bloom syndrome protein isoform 1	3	0	0	3
geminin	13	0	0	13
survival motor neuron protein isoform d	3	0	0	3
muscleblind-like protein 1 isoform 1	3	0	0	3
Carbonic anhydrase	0	2	0	2
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	7	0	7
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
5-hydroxytryptamine receptor 2A	0	7	0	7
Androgen receptor	0	5	0	5
Translocator protein	0	1	1	2
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B6	0	2	0	2
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Adenosine receptor A1	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	2
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	1	0	1
5-hydroxytryptamine receptor 2B	0	7	0	7
Sodium-dependent serotonin transporter	0	8	1	10
Delta-type opioid receptor	0	5	0	6
Cytochrome P450 2C19	0	2	0	2
Delta-type opioid receptor	0	7	1	9
Mu-type opioid receptor	0	7	1	11
Carbonic anhydrase	0	2	0	2
Kappa-type opioid receptor	0	5	0	6
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	4	2	0	6
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	3	0	3
D(2) dopamine receptor	0	6	0	7
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	6	0	6
Fatty-acid amide hydrolase 1	0	2	0	2
Beta-carbonic anhydrase 1	0	3	0	3
Carbonic anhydrase 2	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	3	0	4
Carbonic anhydrase	0	3	0	3
Sigma intracellular receptor 2	0	2	0	2
Delta carbonic anhydrase	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Renin	0	1	0	1
Carbonic anhydrase	0	2	0	2
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	3	1	5
Carbonic anhydrase 4	0	4	0	4
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Ferritin light chain	3	0	0	3
Thymidine kinase	0	1	0	1
phosphopantetheinyl transferase	5	0	0	5
TDP1 protein	16	0	0	16
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
Solute carrier family 22 member 1	0	7	0	8
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	2	0	3
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	4
Thymidine kinase	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	8	0	0	8
pregnane X nuclear receptor	12	0	0	12
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	10	0	10
Muscarinic acetylcholine receptor M2	0	13	1	17
Muscarinic acetylcholine receptor M4	0	12	1	15
Muscarinic acetylcholine receptor M1	0	9	1	12
Muscarinic acetylcholine receptor M3	0	7	1	10
Muscarinic acetylcholine receptor M4	0	7	1	10
Muscarinic acetylcholine receptor M5	0	7	1	10
Muscarinic acetylcholine receptor M5	0	12	1	15
Muscarinic acetylcholine receptor M2	0	8	2	13
Muscarinic acetylcholine receptor M1	0	13	1	17
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	12	1	15
Alpha-1D adrenergic receptor	0	8	0	8
5-hydroxytryptamine receptor 2C	0	10	0	10
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	3	0	0	5
5-hydroxytryptamine receptor 7	0	5	0	5
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
glp-1 receptor, partial	4	0	0	4
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
SMAD family member 2	5	0	0	5
SMAD family member 3	5	0	0	5
caspase 7, apoptosis-related cysteine protease	4	0	0	4
caspase-3	4	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
endonuclease IV	1	0	0	1
WRN	1	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
vitamin D3 receptor isoform VDRA	6	0	0	6
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
importin subunit beta-1 isoform 1	1	0	0	1
flap endonuclease 1	4	0	0	4
serine/threonine-protein kinase PLK1	1	0	0	1
snurportin-1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	3	0	0	3
DNA polymerase kappa isoform 1	4	0	0	4
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-1	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	8	2	2	12
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 7	0	1	0	2
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	1	0	1
Beta-lactamase VIM-1	0	0	0	1
Solute carrier family 22 member 7	0	1	0	2
phosphoglycerate kinase	1	0	0	1
interleukin 8	3	0	0	3
farnesoid X nuclear receptor	6	0	0	6
G	6	0	0	6
cytochrome P450 2D6	7	0	0	7
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
streptokinase A precursor	0	0	3	3
lethal factor (plasmid)	3	0	0	3
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
Interferon beta	8	0	0	8
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
Cellular tumor antigen p53	15	0	0	15
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Inositol hexakisphosphate kinase 1	6	0	0	6
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	6	0	0	6
Proteasome subunit beta type-11	0	0	0	1
acetylcholinesterase	6	0	0	6
Fumarate hydratase	3	0	0	3
USP1 protein, partial	2	0	0	2
NFKB1 protein, partial	2	0	0	2
Thrombopoietin	2	0	0	2
estrogen receptor 2 (ER beta)	8	0	0	8
NADPH oxidase 1	0	1	0	1
polyprotein	3	0	0	3
67.9K protein	1	0	0	1
Snq2p	0	0	0	2
IDH1	4	0	0	4
Adenylate cyclase type 1	0	3	0	3
thyroid stimulating hormone receptor	7	0	0	7
Caspase-7	1	0	0	1
Spike glycoprotein	0	2	2	4
Replicase polyprotein 1ab	0	3	2	5
cytochrome P450 2D6 isoform 1	2	0	0	2
cellular tumor antigen p53 isoform a	3	0	0	3
D(1A) dopamine receptor	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	5	0	0	5
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
mitogen-activated protein kinase 1	5	0	0	5
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
ras-related protein Rab-9A	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
M-phase phosphoprotein 8	3	0	0	3
histone acetyltransferase KAT2A isoform 1	5	0	0	5
muscarinic acetylcholine receptor M1	4	0	0	4
Proteasome subunit alpha type-7	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Transmembrane protease serine 2	0	2	2	4
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Potassium channel subfamily K member 2	0	3	0	3
Epidermal growth factor receptor	0	1	0	1
Albumin	0	1	3	4
Albumin	0	0	3	3
Major prion protein	0	0	3	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Integrin beta-3	3	0	0	3
Tyrosine-protein kinase Fyn	0	1	0	1
Procathepsin L	0	2	2	4
Aldo-keto reductase family 1 member B1	0	9	0	9
ATP-dependent translocase ABCB1	0	5	0	8
Integrin alpha-IIb	3	0	0	3
5-hydroxytryptamine receptor 1A	0	3	1	4
Alpha-2A adrenergic receptor	0	7	1	8
Replicase polyprotein 1a	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Replicase polyprotein 1ab	0	2	2	4
Angiotensin-converting enzyme	0	5	0	5
D(2) dopamine receptor	0	6	1	10
Alpha-1B adrenergic receptor	0	6	0	6
Sphingomyelin phosphodiesterase	0	1	0	1
Alpha-2B adrenergic receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	7	0	7
D	0	5	0	5
D(3) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	7	0	7
Alpha-2B adrenergic receptor	0	5	0	5
D(2) dopamine receptor	0	3	0	3
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	6	0	8
D(4) dopamine receptor	0	4	1	8
D(1B) dopamine receptor	0	3	0	5
Adenylate cyclase type 3	0	3	0	3
Alpha-2C adrenergic receptor	0	5	0	5
UDP-glucuronosyltransferase 1A4	0	0	0	2
Alpha-2A adrenergic receptor	0	5	0	5
Alpha-1D adrenergic receptor	0	6	0	6
Sodium-dependent noradrenaline transporter	0	10	1	11
Sodium-dependent dopamine transporter	0	8	0	8
Histamine H2 receptor	0	6	0	6
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	8	0	8
5-hydroxytryptamine receptor 1B	0	6	0	6
Trypanothione reductase	0	4	0	4
D(4) dopamine receptor	0	4	0	4
Histamine H1 receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	10	1	11
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
5-hydroxytryptamine receptor 7	0	2	0	2
Histamine H1 receptor	0	6	0	6
Mu-type opioid receptor	0	8	4	13
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
D(3) dopamine receptor	0	6	1	10
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	3
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	5	2	8
Kappa-type opioid receptor	0	5	2	8
5-hydroxytryptamine receptor 2B	0	6	0	6
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	6	0	6
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
5-hydroxytryptamine receptor 6	0	5	0	5
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	1	2
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Sodium-dependent dopamine transporter	0	6	1	7
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	15	0	15
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	5	0	5
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
D	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	3	0	3
Proteasome subunit beta type-7	0	0	0	1
Ataxin-2	9	0	0	9
Sigma non-opioid intracellular receptor 1	0	14	0	14
Angiotensin-converting enzyme 2	0	2	2	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	3	0	3
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Liver carboxylesterase 1	0	0	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	4	0	4
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Androgen receptor	0	3	0	3
Luciferase	2	0	0	2
ATPase family AAA domain-containing protein 5	7	0	0	7
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
15-lipoxygenase, partial	2	0	0	2
regulator of G-protein signaling 4	3	0	0	3
nonstructural protein 1	3	0	0	3
glucocerebrosidase	2	0	0	2
peripheral myelin protein 22 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
nuclear receptor ROR-gamma isoform 1	3	0	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Cocaine esterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
Beta-1 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
Histamine H1 receptor	0	2	0	2
C-8 sterol isomerase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
Kappa-type opioid receptor	0	4	1	6
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
TAR DNA-binding protein 43	3	0	0	3
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	3	0	3
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
ATP-dependent phosphofructokinase	6	0	0	6
Chymotrypsinogen A	0	2	0	2
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Potassium channel subfamily K member 3	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Translocator protein	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Kappa-type opioid receptor	0	3	2	6
Mu-type opioid receptor	0	3	2	7
PPM1D protein	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
STE24	0	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
DNA gyrase subunit A	0	1	0	2
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit B	0	1	0	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Myeloperoxidase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	1	2
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Envelope glycoprotein	0	0	1	1
Rhodopsin kinase GRK1	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Sterol 14-alpha-demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	2	2
Aromatase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Sterol 14-alpha demethylase	0	0	2	2
Sterol 14-alpha demethylase	0	1	1	2
14-alpha sterol demethylase	0	0	2	2
14-alpha sterol demethylase	0	0	2	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
pregnane X receptor	2	0	0	2
thioredoxin glutathione reductase	2	0	0	2
huntingtin isoform 2	1	0	0	1
Inositol monophosphatase 1	1	0	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
Guanine nucleotide-binding protein G	1	0	0	1
heat shock protein 90, putative	0	0	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Genome polyprotein	0	1	0	1
Neuraminidase	0	2	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polyphenol oxidase 2	0	2	0	3
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Albumin	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Acetylcholinesterase	0	2	0	2
Substance-P receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Cholinesterase	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
RmtA	0	1	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
cGMP-gated cation channel alpha-1	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Alpha-synuclein	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (1,258)

Protein Targets (868)

Blow Out Fracture

Synonyms(5)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (1,258)

Drugs Studied (96)

Protein Targets (868)