Bartonella henselae Infection

Synonym
Inoculative Lymphoreticulosis
Bartonella henselae Infection
Catscratch Disease
Cat Scratch Disease
Cat Scratch Fever
Inoculation Lymphoreticulosis

Excerpt	Reference
"Cat scratch disease is a subacute regional lymphadenitis usually preceded by a history of being scratched by a cat or young kitten."	( Hooper, DG; Meister, SJ; Peterson, TJ; Ulrich, GG; Waecker, NJ, 1992)
"Cat scratch disease is an infectious lymphadenitis frequently occurring in children and adolescents."	( de Lang, EE; Holt, PD, 1995)
"Cat scratch disease is a rarely diagnosed condition in our environment and it is easily misdiagnosed with other regional lymphadenitis; hence, a serologic test revealing a seroconversion or a significant increase in serologic titers will be very useful, as well as the epidemiologic antecedent of cat exposure."	( Bosch-Aparici, X; Bosch-Mestres, J; Martínez-Orozco, F; Segura-Corrales, J; Solé-Arqués, M, 1998)
"A Bartonella henselae infection is demonstrated by indirect immunofluorescence, and a diagnosis of a Parinaud's oculoglandular syndrome is established."	( Álvarez-Coronado, M; Galindo-Bocero, J; Rozas-Reyes, P; Sánchez-García, S, 2017)

Excerpt	Reference
"Catscratch disease has increased as many children are in close proximity to cats."	( Azri, M; Ismail, IH, 2022)

Excerpt	Reference
"Three patients with cat scratch diseases were treated with pefloxacin (800 mg p."	( Bouhali, R; Breuil, J; Chaplain, C; Lafaix, C; Patey, O; Roucayrol, AM, 1989)
"A 3 year old girl with hepatosplenic cat scratch disease developed prolonged fever unresponsive to treatment with multiple antibiotics, including gentamicin, azithromycin, rifampin, and ciprofloxacin."	( Bryant, K; Marshall, GS, 2003)
"We describe the first case of systemic cat scratch disease in a patient receiving peginterferon alpha-2a and ribavirin for treatment of hepatitis C."	( Berenson, CS; Bhatti, Z, 2007)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	35 (14.64)	23.3326
1990's	54 (22.59)	12.5806
2000's	72 (30.13)	18.1394
2010's	64 (26.78)	28.8240
2020's	14 (5.86)	9.53

Drug	Relationship Strength	Studies	Trials
formaldehyde	low	2	0
glycine	low	1	0
iodine	low	1	0
sarcosine	low	2	0
phenytoin	low	1	0
azathioprine	low	1	0
carbamazepine	low	1	0
carprofen	low	1	0
ciprofloxacin	low	22	0
disopyramide	low	1	0
erythrosine	low	1	0
gentamicin	low	15	0
guaifenesin	low	1	0
ibuprofen	low	1	0
2-propanol	low	1	0
ketorolac	low	1	0
lorazepam	low	1	0
phenylbutazone	low	1	0
sulfamethoxazole	low	3	0
tosufloxacin	low	1	0
trimethoprim	low	3	0
corticosterone	low	1	0
prednisolone	low	6	0
thymidine	low	1	0
prednisolone acetate	low	1	0
prednisone	low	15	0
methylprednisolone acetate	low	1	0
penicillin g	low	1	0
idoxuridine	low	1	0
aminopyrine	low	1	0
methylene blue	low	1	0
ampicillin	low	5	0
methylprednisolone	low	3	0
erythromycin	low	12	0
vancomycin	low	5	0
methylprednisolone hemisuccinate	low	1	0
benzophenoneidum	low	1	0
streptomycin	low	2	0
floxacillin	low	1	0
vidarabine	low	1	0
silver	low	3	0
gadolinium	low	1	0
silver nitrate	low	1	0
trolamine salicylate	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
ribavirin	low	1	0
amikacin	low	1	0
pefloxacin	low	1	0
itraconazole	low	1	0
fosphenytoin	low	1	0
orbifloxacin	low	1	0
glucose, (beta-d)-isomer	low	1	0
cephalosporin c	low	1	0
fluorodeoxyglucose f18	low	4	0
enrofloxacin	low	1	0
panipenem	low	1	0
clarithromycin	low	11	0
imatinib mesylate	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
moxifloxacin	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	10	0
carboplatin	low	1	0
tretinoin	low	1	0
tacrolimus	low	1	0
zithromax	medium	45	1
calcitriol	low	1	0
vitamin d 2	low	1	0
isotretinoin	low	1	0
cefotaxime	low	1	0
gadolinium dtpa	low	1	0
pradofloxacin	low	1	0
amoxicillin-potassium clavulanate combination	low	3	0
technetium tc 99m exametazime	low	1	0
indocyanine green	low	2	0
acid phosphatase	low	1	0
sarkosyl	low	2	0
ro13-9904	low	7	0
tetracycline	low	8	0
chlortetracycline	low	3	0
oxytetracycline, anhydrous	low	1	0
minocycline	low	1	0
rolitetracycline	low	1	0
tigecycline	low	1	0
agar	low	1	0
technetium tc 99m medronate	low	2	0
muramidase	low	2	0
exudates	low	1	0
acyclovir	low	2	0
rifampin	low	32	0
eye	low	4	0

Protein Targets (762)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
RAR-related orphan receptor gamma	21	0	0	21
GLI family zinc finger 3	25	0	0	25
AR protein	34	0	0	34
aldehyde dehydrogenase 1 family, member A1	17	0	0	17
retinoic acid nuclear receptor alpha variant 1	25	0	0	25
retinoid X nuclear receptor alpha	22	0	0	22
estrogen nuclear receptor alpha	43	0	0	43
peroxisome proliferator-activated receptor delta	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	23	0	0	23
activating transcription factor 6	15	0	0	15
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
Histone H2A.x	10	0	0	10
thyroid hormone receptor beta isoform a	11	0	0	11
heat shock protein beta-1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
lamin isoform A-delta10	14	0	0	14
Voltage-dependent calcium channel gamma-2 subunit	14	0	0	14
Glutamate receptor 2	14	0	0	14
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	9	0	0	9
Chain B, HADH2 protein	9	0	0	9
Chain A, ATP-DEPENDENT DNA HELICASE Q1	6	0	0	6
Chain A, Ferritin light chain	10	0	0	10
Thymidine kinase	0	3	0	4
thioredoxin reductase	14	0	0	14
phosphopantetheinyl transferase	8	0	0	8
GLS protein	11	0	0	11
TDP1 protein	30	0	0	30
Smad3	2	0	0	2
thyroid stimulating hormone receptor	8	0	0	8
EWS/FLI fusion protein	10	0	0	10
arylsulfatase A	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	24	0	0	24
Bloom syndrome protein isoform 1	10	0	0	10
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Solute carrier family 22 member 1	0	4	0	5
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	26
Solute carrier family 22 member 6	0	3	0	4
Bile salt export pump	0	8	0	8
Bile salt export pump	0	34	0	34
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	7
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	12	1	14
Cytochrome P450 2J2	0	7	0	7
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	2	0	3
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	4	0	6
Canalicular multispecific organic anion transporter 1	0	25	0	25
Thymidine kinase	0	1	0	2
peripheral myelin protein 22	7	0	0	7
histone acetyltransferase KAT2A isoform 1	8	0	0	8
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	9	0	0	9
Luciferase	14	0	0	14
interleukin 8	9	0	0	9
15-lipoxygenase, partial	3	0	0	3
estrogen receptor 2 (ER beta)	10	0	0	10
nuclear receptor subfamily 1, group I, member 3	15	0	0	15
cytochrome P450 family 3 subfamily A polypeptide 4	15	0	0	15
estrogen-related nuclear receptor alpha	30	0	0	30
pregnane X nuclear receptor	23	0	0	23
G	12	0	0	12
vitamin D (1,25- dihydroxyvitamin D3) receptor	18	0	0	18
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
chromobox protein homolog 1	13	0	0	13
thyroid hormone receptor beta isoform 2	22	0	0	22
histone deacetylase 9 isoform 3	4	0	0	4
geminin	34	0	0	34
Interferon beta	17	0	0	17
HLA class I histocompatibility antigen, B alpha chain	12	0	0	12
Nicotinate phosphoribosyltransferase	0	2	0	2
Inositol hexakisphosphate kinase 1	12	0	0	12
cytochrome P450 2C9, partial	12	0	0	12
ORF73	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	10	0	0	10
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Chain A, Cruzipain	5	0	0	5
Beta-lactamase	0	0	0	3
acid sphingomyelinase	2	0	0	2
apical membrane antigen 1, AMA1	2	0	0	2
farnesoid X nuclear receptor	16	0	0	16
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	0	3
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
DNA polymerase beta	3	0	0	3
DNA polymerase eta isoform 1	4	0	0	4
DNA polymerase iota isoform a (long)	12	0	0	12
DNA polymerase kappa isoform 1	9	0	0	9
Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	6	0	6
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	5	0	5
Solute carrier family 15 member 1	0	1	0	1
Spike glycoprotein	8	0	1	9
10 kDa heat shock protein, mitochondrial	0	6	0	6
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	3	0	3
Thiosulfate sulfurtransferase	0	6	0	6
Metallo-beta-lactamase VIM-13	0	0	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	6	0	6
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	6	0	6
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	3
Beta-lactamase VIM-1	0	0	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
acetylcholinesterase	12	0	0	12
SMAD family member 2	9	0	0	9
ATAD5 protein, partial	5	0	0	5
Fumarate hydratase	4	0	0	4
SMAD family member 3	9	0	0	9
Microtubule-associated protein tau	13	0	0	13
thioredoxin glutathione reductase	8	0	0	8
glucocorticoid receptor [Homo sapiens]	23	0	0	23
polyprotein	4	0	0	4
P53	1	0	0	1
peroxisome proliferator activated receptor gamma	16	0	0	16
IDH1	11	0	0	11
aryl hydrocarbon receptor	12	0	0	12
thyroid stimulating hormone receptor	10	0	0	10
peripheral myelin protein 22 isoform 1	6	0	0	6
cellular tumor antigen p53 isoform a	1	0	0	1
survival motor neuron protein isoform d	8	0	0	8
cytochrome P450 3A4 isoform 1	9	0	0	9
M-phase phosphoprotein 8	4	0	0	4
muscleblind-like protein 1 isoform 1	6	0	0	6
muscarinic acetylcholine receptor M1	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	9	3	0	12
Cellular tumor antigen p53	18	0	0	18
Gamma-aminobutyric acid receptor subunit beta-1	9	3	0	12
Gamma-aminobutyric acid receptor subunit delta	9	3	0	12
Gamma-aminobutyric acid receptor subunit gamma-2	9	3	0	12
Gamma-aminobutyric acid receptor subunit alpha-5	9	3	0	12
Gamma-aminobutyric acid receptor subunit alpha-3	9	3	0	12
Gamma-aminobutyric acid receptor subunit gamma-1	9	3	0	12
Gamma-aminobutyric acid receptor subunit alpha-2	9	3	0	12
Gamma-aminobutyric acid receptor subunit alpha-4	9	3	0	12
Gamma-aminobutyric acid receptor subunit gamma-3	9	3	0	12
Gamma-aminobutyric acid receptor subunit alpha-6	9	3	0	12
Nuclear receptor ROR-gamma	6	1	1	8
Gamma-aminobutyric acid receptor subunit alpha-1	9	3	0	12
Gamma-aminobutyric acid receptor subunit beta-3	9	3	0	12
Gamma-aminobutyric acid receptor subunit beta-2	9	3	0	12
GABA theta subunit	9	3	0	12
ATPase family AAA domain-containing protein 5	10	0	0	10
Ataxin-2	12	0	0	12
Gamma-aminobutyric acid receptor subunit epsilon	9	3	0	12
Protein-arginine deiminase type-4	0	11	0	11
pregnane X receptor	6	0	0	6
caspase 7, apoptosis-related cysteine protease	3	0	0	3
progesterone receptor	15	0	0	15
caspase-3	3	0	0	3
thyrotropin-releasing hormone receptor	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
mitogen-activated protein kinase 1	8	0	0	8
lethal factor (plasmid)	3	0	0	3
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
USP1 protein, partial	12	0	0	12
PPM1D protein	5	0	0	5
nuclear receptor ROR-gamma isoform 1	6	0	0	6
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 1A2	0	1	1	3
Cytochrome P450 3A4	0	9	1	12
Androgen receptor	0	3	0	3
Cytochrome P450 2D6	0	2	1	3
Vitamin D3 receptor	0	1	2	5
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	3	5
Cytochrome P450 2C19	0	2	1	3
Kappa-type opioid receptor	0	0	1	3
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
Vpr	3	0	0	3
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	3
Cytochrome P450 2B6	0	0	2	2
Sodium channel protein type 4 subunit alpha	0	2	0	4
Potassium voltage-gated channel subfamily H member 2	0	10	0	12
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
cytochrome P450 2D6	6	0	0	6
vitamin D3 receptor isoform VDRA	10	0	0	10
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
nonstructural protein 1	8	0	0	8
67.9K protein	7	0	0	7
Complement C5	0	0	1	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	5	0	5
Fatty-acid amide hydrolase 1	0	2	0	2
TAR DNA-binding protein 43	9	0	0	9
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	2
Beta-lactamase	0	0	0	2
Albumin	0	2	7	9
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase	0	0	0	2
B2 metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 7	0	1	0	1
Beta-lactamase	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	2	0	3
Solute carrier family 22 member 7	0	1	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
Caspase-2	0	0	1	1
Inositol monophosphatase 1	3	0	0	3
streptokinase A precursor	0	0	7	7
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	5	1	6
30S ribosomal protein S7	0	5	1	6
50S ribosomal protein L15	0	5	1	6
50S ribosomal protein L10	0	5	1	6
50S ribosomal protein L11	0	5	1	6
50S ribosomal protein L7/L12	0	5	1	6
50S ribosomal protein L19	0	5	1	6
50S ribosomal protein L1	0	5	1	6
50S ribosomal protein L20	0	5	1	6
50S ribosomal protein L27	0	5	1	6
50S ribosomal protein L28	0	5	1	6
50S ribosomal protein L29	0	5	1	6
50S ribosomal protein L31	0	5	1	6
50S ribosomal protein L31 type B	0	5	1	6
50S ribosomal protein L32	0	5	1	6
50S ribosomal protein L33	0	5	1	6
50S ribosomal protein L34	0	5	1	6
50S ribosomal protein L35	0	5	1	6
50S ribosomal protein L36	0	5	1	6
30S ribosomal protein S10	0	5	1	6
30S ribosomal protein S11	0	5	1	6
30S ribosomal protein S12	0	5	1	6
30S ribosomal protein S13	0	5	1	6
30S ribosomal protein S16	0	5	1	6
30S ribosomal protein S18	0	5	1	6
30S ribosomal protein S19	0	5	1	6
30S ribosomal protein S20	0	5	1	6
30S ribosomal protein S2	0	5	1	6
30S ribosomal protein S3	0	5	1	6
30S ribosomal protein S4	0	5	1	6
30S ribosomal protein S5	0	5	1	6
30S ribosomal protein S8	0	5	1	6
30S ribosomal protein S9	0	5	1	6
50S ribosomal protein L13	0	5	1	6
50S ribosomal protein L14	0	5	1	6
50S ribosomal protein L16	0	5	1	6
50S ribosomal protein L23	0	5	1	6
30S ribosomal protein S15	0	5	1	6
50S ribosomal protein L17	0	5	1	6
50S ribosomal protein L21	0	5	1	6
50S ribosomal protein L30	0	5	1	6
50S ribosomal protein L6	0	5	1	6
30S ribosomal protein S14	0	5	1	6
30S ribosomal protein S17	0	5	1	6
30S ribosomal protein S1	0	5	1	6
50S ribosomal protein L18	0	5	1	6
50S ribosomal protein L2	0	5	1	6
50S ribosomal protein L3	0	5	1	6
50S ribosomal protein L24	0	5	1	6
50S ribosomal protein L4	0	5	1	6
50S ribosomal protein L22	0	5	1	6
50S ribosomal protein L5	0	5	1	6
30S ribosomal protein S21	0	5	1	6
50S ribosomal protein L25	0	5	1	6
50S ribosomal protein L36 2	0	5	1	6
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
cytochrome P450 2C9 precursor	3	0	0	3
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	3	0	7
DNA gyrase subunit B	0	3	0	7
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
DNA topoisomerase 2-alpha	0	1	0	5
DNA gyrase subunit A	0	2	0	3
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	4	0	0	4
DNA gyrase subunit B	0	4	0	6
DNA gyrase subunit A	0	4	0	6
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	3	0	3
importin subunit beta-1 isoform 1	6	0	0	6
snurportin-1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
ATP-dependent translocase ABCB1	0	3	0	3
Solute carrier organic anion transporter family member 1B3	0	3	0	4
Solute carrier organic anion transporter family member 1B1	0	4	0	5
NFKB1 protein, partial	3	0	0	3
GALC protein	2	0	0	2
Thrombopoietin	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	3	0	3
Mineralocorticoid receptor	0	2	2	4
Androgen receptor	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	3
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Solute carrier family 22 member 1	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	0	1
Solute carrier family 22 member 2	0	3	0	3
endonuclease IV	3	0	0	3
dopamine D1 receptor	2	0	0	2
regulator of G-protein signaling 4	7	0	0	7
flap endonuclease 1	7	0	0	7
Glucocorticoid receptor	0	8	2	15
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 7	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Multidrug and toxin extrusion protein 2	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	3	0	0	3
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	5	0	0	5
ATP-dependent translocase ABCB1	0	2	0	2
60 kDa chaperonin	0	3	0	3
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
hypothetical protein, conserved	2	0	0	2
eyes absent homolog 2 isoform a	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Asialoglycoprotein receptor 1	0	1	1	2
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	1	3
Sodium- and chloride-dependent glycine transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	1	3
Glutamate receptor ionotropic, NMDA 2B	0	2	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	1	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	1	3
Proton-coupled amino acid transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	1	3
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	1	2
Glutamate receptor ionotropic, NMDA 3A	0	2	1	3
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
transcriptional regulator ERG isoform 3	4	0	0	4
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Epidermal growth factor receptor	0	1	0	1
Fatty acid-binding protein, liver	0	4	0	4
Albumin	0	1	0	2
Cholinesterase	0	1	0	1
Fatty acid-binding protein, intestinal	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Acetylcholinesterase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Caspase-1	0	3	0	3
Adenosine receptor A2a	0	1	0	1
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	2	0	2
Caspase-4	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Thymidine phosphorylase	0	0	0	2
Thymidine kinase	0	0	0	2
glp-1 receptor, partial	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Tyrosine-protein kinase ABL1	0	1	1	2
Cytochrome P450 2C8	0	0	0	1
Mast/stem cell growth factor receptor Kit	0	1	1	2
Breakpoint cluster region protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Cytochrome P450 3A5	0	1	0	2
Parkin	3	0	0	3
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
Ornithine decarboxylase	0	0	0	2
Adenosine receptor A3	0	5	0	5
Retinoic acid receptor alpha	0	2	2	4
Alpha-1B adrenergic receptor	0	7	0	7
Alpha-2B adrenergic receptor	0	2	0	2
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Mitogen-activated protein kinase 1	0	2	0	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	7	0	7
Cellular retinoic acid-binding protein 1	0	0	2	2
Mitogen-activated protein kinase 14	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Translocator protein	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
huntingtin isoform 2	1	0	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
neuropeptide S receptor isoform A	2	0	0	2
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	1	0	2
Glycoprotein hormones alpha chain	1	0	0	1
Amyloid-beta precursor protein	0	2	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	0	1	1
Cruzipain	0	1	0	1
Alpha-synuclein	1	3	0	4
Guanine nucleotide-binding protein G	2	0	0	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
DNA gyrase subunit B	0	1	0	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
ClpP	2	0	0	2
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	2	0	2
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Estrogen receptor 1	0	1	0	1
D(1A) dopamine receptor	1	0	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
NS5	0	0	1	1
alpha-galactosidase	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Transmembrane protease serine 2	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Insulin-degrading enzyme	0	1	0	1
DNA repair protein RAD52 homolog	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Dihydrofolate reductase	0	3	0	4
Endothelin-1 receptor	0	1	0	1
Protease	0	1	1	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidylate synthase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
cytochrome P450 2C19 precursor	1	0	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
Adenosine deaminase	0	0	0	1
RNA-directed RNA polymerase	0	1	1	2
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bartonella henselae Infection

Synonyms(6)

Research Excerpts

Overview

Context

Treatment

Research

Studies (239)

Protein Targets (762)

Bartonella henselae Infection

Synonyms(6)

Research Excerpts

Overview

Context

Treatment

Research

Studies (239)

Drugs Studied (103)

Protein Targets (762)