Central Nervous System Infection

Pathogenic infections of the brain, spinal cord, and meninges. DNA VIRUS INFECTIONS; RNA VIRUS INFECTIONS; BACTERIAL INFECTIONS; MYCOPLASMA INFECTIONS; SPIROCHAETALES INFECTIONS; fungal infections; PROTOZOAN INFECTIONS; HELMINTHIASIS; and PRION DISEASES may involve the central nervous system as a primary or secondary process.

Synonym
CNS Infections
Infections, Central Nervous System
Central Nervous System Infection
Central Nervous System Infections

Excerpt	Reference
"CNS infections are associated with significant decreases in serum urate levels in comparison with previous values."	( Blanco, MS; Collazos, J; Guerra, E; Martínez, E; Mayo, J, 2000)
"When CNS infections are caused by multi-drug resistant Gram-negative bacteria, intrathecal colistin is considered an effective and safe option."	( Bargiacchi, O; De Rosa, FG, 2016)

Excerpt	Reference
"Suspected central nervous system infection was investigated and treated with cefotaxime."	( Adebajo, A; Grandidge, L; Sharlala, H; Thistleton, S, 2014)
"Antimicrobial treatment of CNS infections should be based not only on the susceptibility of the isolated microorganism, but also on the treatment's pharmacokinetic properties demonstrating the passage of the molecule through the blood-brain barrier."	( Bargiacchi, O; De Rosa, FG, 2016)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	1 (0.52)	23.3326
1990's	10 (5.21)	12.5806
2000's	58 (30.21)	18.1394
2010's	82 (42.71)	28.8240
2020's	41 (21.35)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
carbon monoxide	low	1	0
salicylic acid	low	1	0
lactic acid	low	7	0
glycerol	low	1	0
kynurenine	low	2	0
inositol	low	1	0
niacinamide	low	1	0
pyrazinamide	low	1	0
thiamine	low	1	0
uric acid	low	1	0
pleconaril	low	2	0
homovanillic acid	low	1	0
phenytoin	low	3	0
albendazole	low	1	0
diminazene	low	1	0
carbamazepine	low	1	0
cefuroxime	medium	1	1
ciprofloxacin	low	1	0
clonazepam	low	1	0
diazepam	low	3	0
valproic acid	low	2	0
erythrosine	low	1	0
fluconazole	low	1	0
fluorouracil	low	1	0
foscarnet	low	1	0
gentamicin	low	2	0
guanidine	low	1	0
lidocaine	low	1	0
isoniazid	low	1	0
lorazepam	low	1	0
midazolam	low	4	0
phenobarbital	low	2	0
propofol	low	1	0
prednisolone	medium	4	1
prednisone	low	2	0
penicillin g	low	1	0
chloramphenicol	low	1	0
aspartic acid	low	1	0
apomorphine	low	1	0
bromodeoxyuridine	low	1	0
methicillin	low	2	0
mannitol	medium	2	1
tryptophan	low	3	0
methylprednisolone	medium	1	1
nafcillin	low	1	0
oxazoles	low	3	0
gentian violet	low	1	0
vancomycin	low	9	0
stavudine	low	1	0
streptomycin	low	2	0
titanium	low	1	0
gadolinium	low	1	0
zalcitabine	low	1	0
trolamine salicylate	low	1	0
transferrin	low	1	0
cefazolin	low	2	0
ribavirin	low	1	0
amikacin	low	4	0
simvastatin	low	1	0
itraconazole	low	2	0
efavirenz	low	1	0
cephalosporin c	medium	6	1
triazoles	medium	6	1
fluorodeoxyglucose f18	low	2	0
voriconazole	low	9	0
oxazolidin-2-one	medium	4	1
d-aspartic acid	low	1	0
lopinavir	medium	1	1
glycidyl nitrate	low	1	0
oxoglaucine	low	1	0
quinapyramine	low	1	0
methotrexate	low	1	0
carbapenems	low	2	0
beta-lactams	low	1	0
anidulafungin	low	1	0
colistimethate sodium	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	7	0
ritonavir	medium	1	1
fibrin	low	1	0
epiglucan	low	1	0
oxytocin	low	1	0
meropenem	low	3	0
linezolid	medium	6	1
n-formylmethionine leucyl-phenylalanine	low	1	0
clindamycin	medium	4	1
fosfomycin	low	1	0
zithromax	low	1	0
l 743,872	low	1	0
micafungin	low	1	0
isomethyleugenol	low	1	0
ethionamide	low	1	0
thiopental	low	1	0
maraviroc	medium	1	1
methyl prednisolonate	medium	1	1
sphingosine	low	1	0
amphotericin b	low	10	0
phenylephrine hydrochloride	low	3	0
diminazene aceturate	low	1	0
biliverdine	low	1	0
indinavir sulfate	low	1	0
cefotaxime	low	2	0
rivaroxaban	low	1	0
oxadiazoles	low	2	0
tedizolid phosphate	low	1	0
technetium tc 99m exametazime	low	1	0
pituitrin	low	1	0
virginiamycin	low	2	0
clove	low	1	0
atrial natriuretic factor	low	1	0
enfuvirtide	medium	1	1
phosphatidylcholines	low	1	0
raltegravir potassium	low	1	0
ro13-9904	medium	7	1
quinupristin	low	2	0
pci 32765	low	1	0
piperidines	low	1	0
colistin	low	8	0
ascorbic acid	low	1	0
tetracycline	low	2	0
minocycline	medium	3	1
tigecycline	low	5	0
dolutegravir	low	1	0
calca protein, human	low	1	0
transforming growth factor beta	low	1	0
gsk-2816126	low	1	0
daptomycin	low	1	0
dalfopristin	low	2	0
cyclosporine	low	1	0
flavin mononucleotide	low	1	0
thromboplastin	low	1	0
amyloid beta-peptides	low	1	0
exudates	low	2	0
acyclovir	low	10	0
inosine diphosphate	low	1	0
neopterin	medium	6	1
rifampin	medium	4	1
filipin	low	1	0

Protein Targets (1,388)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Ferritin light chain	10	0	0	10
Thymidine kinase	0	1	0	1
thioredoxin reductase	15	0	0	15
phosphopantetheinyl transferase	14	0	0	14
GLS protein	12	0	0	12
TDP1 protein	34	0	0	34
Smad3	8	0	0	8
thyroid stimulating hormone receptor	12	0	0	12
EWS/FLI fusion protein	21	0	0	21
arylsulfatase A	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	24	0	0	24
activating transcription factor 6	11	0	0	11
Histone H2A.x	13	0	0	13
Bloom syndrome protein isoform 1	13	0	0	13
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
lamin isoform A-delta10	32	0	0	32
Solute carrier family 22 member 1	0	5	0	8
ATP-binding cassette sub-family C member 3	0	34	0	34
Multidrug resistance-associated protein 4	0	34	0	36
Solute carrier family 22 member 6	0	4	0	5
Bile salt export pump	0	9	0	9
Bile salt export pump	0	42	0	42
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	4
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	16	0	18
Cytochrome P450 2J2	0	4	0	4
Disintegrin and metalloproteinase domain-containing protein 17	2	1	0	3
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	3	0	6
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	5	0	8
Canalicular multispecific organic anion transporter 1	0	33	0	33
Thymidine kinase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	16	0	0	16
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
RAR-related orphan receptor gamma	23	0	0	23
AR protein	34	0	0	34
nuclear receptor subfamily 1, group I, member 3	20	0	0	20
cytochrome P450 family 3 subfamily A polypeptide 4	23	0	0	23
glucocorticoid receptor [Homo sapiens]	29	0	0	29
estrogen-related nuclear receptor alpha	36	0	0	36
pregnane X nuclear receptor	22	0	0	22
estrogen nuclear receptor alpha	44	0	0	44
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 2	14	0	0	14
heat shock protein beta-1	8	0	0	8
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	14	0	0	14
Cyclin-dependent kinase 1	0	1	1	2
Heat shock protein HSP 90-beta	0	1	0	1
Glutamate receptor 2	14	0	0	14
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	7	0	0	7
Protein mono-ADP-ribosyltransferase PARP15	0	3	0	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	16	0	0	16
Ataxin-2	17	0	0	17
Chain A, Beta-lactamase	7	0	0	7
Luciferase	10	0	0	10
glp-1 receptor, partial	5	0	0	5
hypoxia-inducible factor 1 alpha subunit	9	0	0	9
ATAD5 protein, partial	11	0	0	11
Fumarate hydratase	8	0	0	8
GLI family zinc finger 3	29	0	0	29
caspase 7, apoptosis-related cysteine protease	4	0	0	4
progesterone receptor	15	0	0	15
retinoic acid nuclear receptor alpha variant 1	28	0	0	28
retinoid X nuclear receptor alpha	21	0	0	21
farnesoid X nuclear receptor	17	0	0	17
polyprotein	8	0	0	8
67.9K protein	9	0	0	9
peroxisome proliferator activated receptor gamma	17	0	0	17
vitamin D (1,25- dihydroxyvitamin D3) receptor	17	0	0	17
caspase-3	4	0	0	4
IDH1	12	0	0	12
aryl hydrocarbon receptor	11	0	0	11
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
nuclear receptor subfamily 1, group I, member 2	9	0	0	9
cellular tumor antigen p53 isoform a	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
chromobox protein homolog 1	17	0	0	17
transcriptional regulator ERG isoform 3	4	0	0	4
thyroid hormone receptor beta isoform 2	22	0	0	22
histone deacetylase 9 isoform 3	2	0	0	2
mitogen-activated protein kinase 1	11	0	0	11
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
geminin	31	0	0	31
Vif	0	0	0	1
peripheral myelin protein 22	11	0	0	11
survival motor neuron protein isoform d	7	0	0	7
muscleblind-like protein 1 isoform 1	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
neuropeptide S receptor isoform A	3	0	0	3
Interferon beta	22	0	0	22
Cellular tumor antigen p53	24	0	0	24
Integrin beta-3	5	0	0	5
Integrin alpha-IIb	5	0	0	5
Methionine aminopeptidase	0	1	0	1
Fatty-acid amide hydrolase 1	1	4	0	5
Inositol monophosphatase 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	9	0	0	9
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	11	0	0	11
Chain A, Cruzipain	6	0	0	6
interleukin 8	8	0	0	8
peroxisome proliferator-activated receptor delta	15	0	0	15
tumor necrosis factor	2	0	0	2
vitamin D3 receptor isoform VDRA	12	0	0	12
nuclear factor erythroid 2-related factor 2 isoform 1	27	0	0	27
Cytochrome P450 1A2	0	10	0	11
Cytochrome P450 3A4	0	20	0	24
Cytochrome P450 2D6	0	11	0	12
Cytochrome P450 2C19	0	11	0	13
Nuclear receptor ROR-gamma	9	0	0	9
Potassium voltage-gated channel subfamily H member 2	0	13	0	14
Aurora kinase B	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	0	8
Replicase polyprotein 1ab	0	5	2	7
Cytochrome P450 2C8	0	4	0	5
Cytochrome P450 2B6	0	3	2	7
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	10	0	0	10
acetylcholinesterase	9	0	0	9
Microtubule-associated protein tau	14	0	0	15
aldehyde dehydrogenase 1 family, member A1	18	0	0	18
estrogen receptor 2 (ER beta)	14	0	0	14
regulator of G-protein signaling 4	5	0	0	5
cytochrome P450 2D6	13	0	0	13
thyroid stimulating hormone receptor	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
cytochrome P450 2D6 isoform 1	3	0	0	3
cytochrome P450 2C19 precursor	3	0	0	3
cytochrome P450 2C9 precursor	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	9	0	0	9
nuclear receptor ROR-gamma isoform 1	9	0	0	9
cytochrome P450 3A4 isoform 1	10	0	0	10
lethal factor (plasmid)	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	10	8	2	20
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	3
Tryptophan 5-hydroxylase 1	0	1	0	1
D(2) dopamine receptor	0	4	2	8
5-hydroxytryptamine receptor 2A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	10	8	2	20
Alpha-1B adrenergic receptor	0	8	0	8
Gamma-aminobutyric acid receptor subunit delta	10	8	2	20
Gamma-aminobutyric acid receptor subunit gamma-2	10	8	3	21
D	0	2	0	2
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	4	1	6
Alpha-2B adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	10	8	2	20
Gamma-aminobutyric acid receptor subunit alpha-3	10	8	2	20
D(2) dopamine receptor	0	2	0	2
D(1A) dopamine receptor	0	4	2	8
D(4) dopamine receptor	0	2	1	4
D(1B) dopamine receptor	0	2	0	3
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	10	8	2	20
Gamma-aminobutyric acid receptor subunit alpha-2	10	8	2	20
Alpha-1D adrenergic receptor	0	6	0	6
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	10	8	2	20
Gamma-aminobutyric acid receptor subunit gamma-3	10	8	2	20
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	10	8	2	20
D(4) dopamine receptor	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
D(3) dopamine receptor	0	4	1	6
5-hydroxytryptamine receptor 3A	0	1	0	1
Alpha-1A adrenergic receptor	0	8	0	8
Histamine H2 receptor	6	0	0	6
5-hydroxytryptamine receptor 7	0	1	0	1
Spike glycoprotein	11	0	2	13
D(2) dopamine receptor	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-1	10	8	3	21
Gamma-aminobutyric acid receptor subunit beta-3	10	8	2	20
Gamma-aminobutyric acid receptor subunit beta-2	10	8	3	21
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
GABA theta subunit	10	8	2	20
D	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	10	8	2	20
5-hydroxytryptamine receptor 3B	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	6	0	0	6
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Polyphenol oxidase 2	0	4	0	6
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	2	1	3
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	0	2	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	2	2
Carbonic anhydrase 1	0	4	0	7
Carbonic anhydrase 2	0	5	1	8
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	2
Excitatory amino acid transporter 1	0	2	0	2
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	2
Glutamate receptor ionotropic, NMDA 2B	0	1	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	2
Metabotropic glutamate receptor 1	0	0	2	2
Metabotropic glutamate receptor 2	0	0	2	2
Carbonic anhydrase-like protein, putative	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	2
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
NFKB1 protein, partial	3	0	0	3
D(1A) dopamine receptor	2	0	0	2
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
pregnane X receptor	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
Nuclear hormone receptor family member daf-12	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
oxysterols receptor LXR-beta isoform 1	0	0	1	1
muscarinic acetylcholine receptor M1	7	0	0	7
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
USP1 protein, partial	9	0	0	9
thyroid hormone receptor beta isoform a	10	0	0	10
Vpr	4	0	0	4
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	5
Sodium channel protein type 9 subunit alpha	0	4	0	4
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
apical membrane antigen 1, AMA1	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 22 member 11	0	2	0	4
Solute carrier family 22 member 8	0	3	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	1	4
Metallo-beta-lactamase VIM-11	0	0	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-19	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	2
Albumin	0	1	7	15
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase	0	0	0	3
Kappa-type opioid receptor	0	1	0	3
B2 metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Metallo-beta-lactamase VIM-13	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 7	0	1	0	3
Metallo-beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-b-lactamase	0	0	0	3
BlaVIM-1	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	1	4
Beta-lactamase VIM-1	0	0	0	3
Solute carrier family 22 member 7	0	1	0	2
G	18	0	0	18
DNA polymerase iota isoform a (long)	8	0	0	8
streptokinase A precursor	0	0	6	6
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
HLA class I histocompatibility antigen, B alpha chain	18	0	0	18
30S ribosomal protein S6	0	4	0	4
30S ribosomal protein S7	0	4	0	4
50S ribosomal protein L15	0	4	0	4
50S ribosomal protein L10	0	4	0	4
50S ribosomal protein L11	0	4	0	4
50S ribosomal protein L7/L12	0	4	0	4
50S ribosomal protein L19	0	4	0	4
50S ribosomal protein L1	0	4	0	4
50S ribosomal protein L20	0	4	0	4
50S ribosomal protein L27	0	4	0	4
50S ribosomal protein L28	0	4	0	4
50S ribosomal protein L29	0	4	0	4
50S ribosomal protein L31	0	4	0	4
50S ribosomal protein L31 type B	0	4	0	4
50S ribosomal protein L32	0	4	0	4
50S ribosomal protein L33	0	4	0	4
50S ribosomal protein L34	0	4	0	4
50S ribosomal protein L35	0	4	0	4
50S ribosomal protein L36	0	4	0	4
30S ribosomal protein S10	0	4	0	4
30S ribosomal protein S11	0	4	0	4
30S ribosomal protein S12	0	4	0	4
30S ribosomal protein S13	0	4	0	4
30S ribosomal protein S16	0	4	0	4
30S ribosomal protein S18	0	4	0	4
30S ribosomal protein S19	0	4	0	4
30S ribosomal protein S20	0	4	0	4
30S ribosomal protein S2	0	4	0	4
30S ribosomal protein S3	0	4	0	4
30S ribosomal protein S4	0	4	0	4
30S ribosomal protein S5	0	4	0	4
30S ribosomal protein S8	0	4	0	4
30S ribosomal protein S9	0	4	0	4
50S ribosomal protein L13	0	4	0	4
50S ribosomal protein L14	0	4	0	4
50S ribosomal protein L16	0	4	0	4
50S ribosomal protein L23	0	4	0	4
30S ribosomal protein S15	0	4	0	4
50S ribosomal protein L17	0	4	0	4
50S ribosomal protein L21	0	4	0	4
50S ribosomal protein L30	0	4	0	4
50S ribosomal protein L6	0	4	0	4
30S ribosomal protein S14	0	4	0	4
30S ribosomal protein S17	0	4	0	4
30S ribosomal protein S1	0	4	0	4
50S ribosomal protein L18	0	4	0	4
50S ribosomal protein L2	0	4	0	4
50S ribosomal protein L3	0	4	0	4
50S ribosomal protein L24	0	4	0	4
50S ribosomal protein L4	0	4	0	4
50S ribosomal protein L22	0	4	0	4
50S ribosomal protein L5	0	4	0	4
30S ribosomal protein S21	0	4	0	4
50S ribosomal protein L25	0	4	0	4
50S ribosomal protein L36 2	0	4	0	4
Inositol hexakisphosphate kinase 1	18	0	0	18
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	18	0	0	18
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	3	0	5
DNA gyrase subunit B	0	3	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	1	5
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	4	1	5
Protein-arginine deiminase type-4	0	8	0	8
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	5
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	5
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	3	9
Gamma-aminobutyric acid receptor subunit beta-1	0	5	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	2	8
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	5
Gamma-aminobutyric acid receptor subunit beta-3	0	6	2	8
Translocator protein	0	2	0	2
Translocator protein	0	3	0	3
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	5	3	8
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	2	7
Gamma-aminobutyric acid receptor subunit beta-2	0	5	2	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	1	6
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	5	1	6
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
Gamma-aminobutyric acid	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Fatty acid-binding protein, liver	0	3	0	3
Alpha-1-acid glycoprotein 1	0	0	0	1
ATP-dependent translocase ABCB1	0	7	0	8
Translocator protein	0	3	1	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Cathepsin B	0	1	0	1
Furin	0	1	0	1
Amiloride-sensitive amine oxidase [copper-containing]	0	1	0	1
Diamine acetyltransferase 1	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Acid-sensing ion channel 2	0	1	0	1
Chain A, PFV integrase	0	1	0	1
Chain A, PFV integrase	0	1	0	1
Chain A, PFV integrase	0	1	0	1
Solute carrier family 22 member 2	0	4	0	4
Cytochrome P450 2A6	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	3	0	4
Integrase	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Vesicular acetylcholine transporter	0	1	0	1
Reverse transcriptase/RNaseH	0	6	4	17
Solute carrier organic anion transporter family member 1B3	0	5	0	7
Solute carrier organic anion transporter family member 1B1	0	6	0	7
Chain A, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
SMAD family member 2	6	0	0	6
PPM1D protein	4	0	0	4
SMAD family member 3	6	0	0	6
Prothrombin	0	1	0	1
Gag-Pol polyprotein	0	4	0	4
Gag-Pol polyprotein	0	5	0	5
Acetylcholinesterase	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Microsomal triglyceride transfer protein large subunit	0	1	0	1
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120	0	1	0	1
Protease	0	5	3	13
Fructose-1,6-bisphosphatase 1	0	0	0	1
Reverse transcriptase	0	1	1	2
Cholesterol 24-hydroxylase	0	2	2	4
Env polyprotein	0	0	2	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
hypothetical protein, conserved	2	0	0	2
thyrotropin-releasing hormone receptor	2	0	0	2
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase kappa isoform 1	5	0	0	5
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
DNA polymerase beta	5	0	0	5
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
unnamed protein product	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	3	0	3
Rap guanine nucleotide exchange factor 3	2	0	0	2
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Lanosterol 14-alpha demethylase	0	1	2	3
Aromatase	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	3	0	3
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Histone deacetylase 1	0	3	0	3
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	2	2
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
14-alpha sterol demethylase	0	0	2	2
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
heat shock protein 90, putative	0	0	0	1
likely tRNA 2'-phosphotransferase	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
endonuclease IV	4	0	0	4
Skn7p	0	0	0	1
Thrombopoietin	2	0	0	2
nonstructural protein 1	3	0	0	3
peripheral myelin protein 22 isoform 1	4	0	0	4
huntingtin isoform 2	3	0	0	3
flap endonuclease 1	7	0	0	7
Solute carrier family 22 member 8	0	3	0	5
Epidermal growth factor receptor	0	4	2	6
Amyloid-beta precursor protein	1	1	0	2
Thymidylate synthase	0	3	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Carbonic anhydrase 4	0	2	0	3
DNA polymerase delta catalytic subunit	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	3
Carbonic anhydrase 9	0	2	0	3
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
alpha synuclein, partial	1	0	0	1
glucocerebrosidase	2	0	0	2
luciferase	1	0	0	1
Caspase-7	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
caspase-3	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Tyrosine-protein kinase Fyn	0	2	1	3
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	3	0	3
60 kDa chaperonin	0	1	0	1
Adenosine receptor A3	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Muscarinic acetylcholine receptor M1	0	2	0	2
Androgen receptor	0	5	0	5
Alpha-2C adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Substance-K receptor	0	6	0	6
Acetylcholinesterase	0	2	0	2
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Adenosine receptor A2a	0	3	0	3
Mu-type opioid receptor	0	4	0	4
Kappa-type opioid receptor	0	4	0	4
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
10 kDa heat shock protein, mitochondrial	0	3	0	3
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Leukotriene B4 receptor 1	1	0	0	1
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	3	0	3
Glutamate receptor ionotropic, kainate 5	1	0	0	1
10 kDa chaperonin	0	3	0	3
Leukotriene B4 receptor 2	1	0	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Polycomb protein EED	0	1	0	1
Polycomb protein SUZ12	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	2	0	2
Solute carrier family 22 member 3	0	5	0	5
Solute carrier family 22 member 1	0	4	0	5
Solute carrier family 22 member 2	0	3	0	4
ClpP	2	0	0	2
lysosomal alpha-glucosidase preproprotein	2	0	0	2
M-phase phosphoprotein 8	3	0	0	3
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, POL polyprotein	0	2	0	2
Chain B, POL polyprotein	0	2	0	2
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Gag-Pol polyprotein	0	4	0	4
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
Replicase polyprotein 1ab	0	2	2	4
Thromboxane-A synthase	0	2	0	2
Gag-Pol polyprotein	0	3	0	3
Thromboxane-A synthase	0	0	0	2
Genome polyprotein	0	1	1	3
Multidrug and toxin extrusion protein 2	0	3	0	3
Multidrug and toxin extrusion protein 1	0	4	0	4
Protease	0	6	4	10
Protease	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	2	0	2
Formamidopyrimidine-DNA glycosylase	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
GALC protein	3	0	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Estrogen receptor	0	0	2	2
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Prostaglandin G/H synthase 1	0	3	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	2	2
Renin	0	1	0	1
Chain A, protease	0	1	0	1
Chain B, protease	0	1	0	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, protease	0	0	1	1
Chain B, protease	0	0	1	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, Protease	0	1	0	1
Chain B, Protease	0	1	0	1
Chain A, PROTEASE RETROPEPSIN	0	1	0	1
Chain B, PROTEASE RETROPEPSIN	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Chain A, Protease Retropepsin	0	1	0	1
Chain B, Protease Retropepsin	0	1	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Transmembrane protease serine 2	0	0	2	2
Gag-Pol polyprotein	0	2	0	2
Procathepsin L	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
CAAX prenyl protease 1 homolog	0	1	0	1
Plasmepsin V	0	2	0	2
Angiotensin-converting enzyme 2	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Delta-type opioid receptor	0	2	0	2
C-C chemokine receptor type 5	0	1	2	4
C-C chemokine receptor type 5	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
C-C chemokine receptor type 5	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	1	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	1	3
Beta-lactamase IMP-1	0	0	0	2
Beta-lactamase	0	0	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	2	0	0	2
dopamine D1 receptor	2	0	0	2
15-lipoxygenase, partial	3	0	0	3
Thymidylate synthase	0	1	0	1
alpha-galactosidase	4	0	0	4
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
DNA polymerase eta isoform 1	3	0	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	2	0	2
caspase-1 isoform alpha precursor	2	0	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	2	2
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Stromelysin-1	0	3	1	4
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Formyl peptide receptor-related sequence 1	0	0	1	1
fMet-Leu-Phe receptor	0	2	2	4
N-formyl peptide receptor 2	0	0	2	2
FML2_HUMAN	0	0	1	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	2	0	2
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
NAD-dependent protein deacetylase	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
POsterior Segregation	0	0	1	1
Sodium-dependent noradrenaline transporter	0	2	1	3
CREB-binding protein	1	0	0	1
Zinc finger protein mex-5	0	0	1	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1a receptor	0	4	1	5
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Putative nucleoside diphosphate kinase	0	0	1	1
Tyrosine-protein kinase JAK2	0	2	0	2
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	1	2
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	1	1	2
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	1	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	1	0	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Serine/threonine-protein kinase pim-1	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	0	1	1
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	1	0	1
Multifunctional protein ADE2	0	0	1	1
Nucleoside diphosphate kinase B	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	2	1	3
G1/S-specific cyclin-E1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	1	1	2
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	1	2
Receptor-type tyrosine-protein kinase FLT3	0	2	1	3
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Tyrosine-protein kinase CSK	0	1	1	2
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	1	1	2
Tyrosine-protein kinase TXK	0	1	1	2
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	1	1	2
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	1	1	2
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Cytoplasmic tyrosine-protein kinase BMX	0	2	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Tyrosine-protein kinase JAK3	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	2
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	2	2	4
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	1	1	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	1	1	2
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	1	1	2
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Peroxiredoxin-like 2A	0	1	0	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Platelet glycoprotein VI	0	1	0	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	2
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Genome polyprotein	0	0	2	2
Genome polyprotein	0	0	1	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Aldo-keto reductase family 1 member B1	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
NS5	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Prothrombin	0	1	0	1
Coagulation factor X	0	2	0	2
Coagulation factor XII	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Carbonic anhydrase 12	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Carbonic anhydrase 3	0	1	0	2
Tyrosine-protein phosphatase YopH	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Carbonic anhydrase 6	0	2	0	3
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 7	0	1	0	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	2
Carbonic anhydrase 13	0	1	0	2
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
Carbonic anhydrase 14	0	1	0	2
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
PINK1	1	0	0	1
Parkin	1	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
Thymidine kinase 2	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Substance-P receptor	0	1	0	1
Carbonic anhydrase	0	0	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Carbonic anhydrase	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase	0	0	0	1
Tryprostatin B synthase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Carbonic anhydrase	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Cocaine esterase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
C-X-C chemokine receptor type 4	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Central Nervous System Infection

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (192)

Protein Targets (1,388)

Central Nervous System Infection

Synonyms(4)

Research Excerpts

Overview

Treatment

Research

Studies (192)

Drugs Studied (154)

Protein Targets (1,388)