Borrelia hermsii Infection

An acute infection characterized by recurrent episodes of PYREXIA alternating with asymptomatic intervals of apparent recovery. This condition is caused by SPIROCHETES of the genus BORRELIA. It is transmitted by the BITES of either the body louse (PEDICULUS humanus corporis), for which humans are the reservoir, or by soft ticks of the genus ORNITHODOROS, for which rodents and other animals are the principal reservoirs.

Synonym
Borrelia recurrentis Infection
Relapsing Fever
Tick-borne Relapsing Fever
Louse-borne Relapsing Fever
Borrelia hermsii Infection

Excerpt	Reference
"Because tick-borne relapsing fever is eventually a self-limited disease in most patients, it is probably not recognized often enough."	( Fihn, S; Larson, EB, 1980)
"Relapsing fever is also associated with the infection of a variety of tissues, such as the central nervous system."	( Alugupalli, KR; Barbour, AG; Leong, JM; Magoun, L; Parveen, N; Robbins, D; Schwan, TG; Zückert, WR, 2000)
"Relapsing fever is a worldwide, endemic disease caused by several spirochetal species belonging to the genus Borrelia."	( Benz, R; Bergström, S; Bunikis, I; Cutler, S; Denker, K; Drancourt, M; Larsson, C; Lottspeich, F; Mentele, R; Schwan, TG; Thein, M, 2008)
"Relapsing fever is caused by the Borrelia species of spirochetes."	( Ayazi, P; Esmailzadehha, N; Mahyar, A; Nooroozi, S; Oveisi, S, 2015)

Excerpt	Reference
"Twelve men with louse-borne relapsing fever were treated with single doses of procaine penicillin plus aluminum monostearate (PAM) intramuscularly or of tetracycline intravenously."	( Bing, DH; Krause, DW; MacDougal, SJ; Perine, PL; Warrell, DA, 1983)
"In patients with louse-borne relapsing fever (Borrelia recurrentis infection), antimicrobial treatment is often followed by sudden fever, rigors, and persistent hypotension (Jarisch-Herxheimer reactions) that are associated with increases in plasma concentrations of tumor necrosis factor alpha (TNF-alpha), interleukin-6, and interleukin-8."	( Coxon, RE; Fekade, D; Hussein, K; Knox, K; Lalloo, DG; Melka, A; Warrell, DA, 1996)
"Fifteen patients with confirmed relapsing fever were infused intravenously with pentoxifylline 90 min before intramuscular injection of penicillin; 4 patients were not treated with pentoxifylline."	( Fekade, D; Griffin, G; Negussie, Y; Remick, DG, 1996)
"The optimum treatment for louse-borne relapsing fever (LBRF) has not been fully established."	( Doherty, T; Guerrier, G, 2011)
"Louse-borne relapsing fever (LBRF) with high untreated mortality caused by spirochete Borrelia recurrentis is predominantly endemic to Sub-Saharan Africa and has re-emerged in parts of Eastern Europe, Asia and Latin America due to population migrations."	( Anbarasu, A; Basu, S; Debroy, R; Kumar, H; Ramaiah, S; Singh, H, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	84 (56.00)	23.3326
1990's	17 (11.33)	12.5806
2000's	19 (12.67)	18.1394
2010's	24 (16.00)	28.8240
2020's	6 (4.00)	9.53

Drug	Relationship Strength	Studies	Trials
quinacrine	low	1	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	1	0
acetaminophen	low	1	0
cefuroxime	low	1	0
ciprofloxacin	low	1	0
ddt	low	3	0
fluorouracil	low	1	0
glutaral	low	1	0
hydrochlorothiazide	low	1	0
2-propanol	low	1	0
ketorolac	low	1	0
metoclopramide	low	1	0
pentoxifylline	medium	1	1
pyrimethamine	low	1	0
stearic acid	medium	1	1
trimethoprim	low	1	0
prednisolone	medium	3	1
cephaloridine	low	1	0
prednisone	low	1	0
etiocholanolone	low	2	0
penicillin g	low	12	0
chloramphenicol	low	9	0
edetic acid	low	1	0
colchicine	low	2	0
ampicillin	low	1	0
arginine	low	1	0
ethyl chloride	low	1	0
methylprednisolone	low	1	0
oxophenarsine	low	3	0
erythromycin	low	7	0
vancomycin	low	1	0
streptomycin	low	2	0
gold	low	1	0
trolamine salicylate	low	3	0
transferrin	low	1	0
amoxicillin	low	1	0
amikacin	low	1	0
permethrin	low	1	0
meptazinol	medium	2	1
acridine orange	low	3	0
cephalosporin c	medium	2	1
fibrinogen	low	3	0
glycidyl nitrate	low	1	0
pixantrone	medium	1	1
fibrin	low	1	0
mevalonic acid	low	1	0
meropenem	medium	1	1
erythromycin ethylsuccinate	low	1	0
fosfomycin	low	1	0
arsphenamine	low	2	0
sodium dodecyl sulfate	low	1	0
luteolin	low	1	0
naloxone	medium	1	1
lysophosphatidylcholines	low	1	0
aluminum	medium	1	1
arsenic	low	5	0
fenpyroximate	low	1	0
clove	low	2	0
acid phosphatase	low	1	0
phosphatidylcholines	low	1	0
ro13-9904	low	14	0
neoarsphenamine	low	2	0
cardiovascular agents	low	1	0
glycolipids	low	1	0
interleukin-8	medium	5	3
tetracycline	medium	38	5
chlortetracycline	low	11	0
oxytetracycline, anhydrous	low	6	0
minocycline	medium	2	1
demeclocycline	low	1	0
thromboplastin	low	1	0
chondroitin sulfates	low	1	0
cyclic gmp	low	1	0
bis(3',5')-cyclic diguanylic acid	low	1	0
eye	low	3	0

Protein Targets (847)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	9	0	0	9
USP1 protein, partial	7	0	0	7
TDP1 protein	15	0	0	15
vitamin D3 receptor isoform VDRA	6	0	0	6
importin subunit beta-1 isoform 1	3	0	0	3
flap endonuclease 1	8	0	0	8
serine/threonine-protein kinase PLK1	3	0	0	3
snurportin-1	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	10	0	0	10
urokinase-type plasminogen activator precursor	6	0	0	6
plasminogen precursor	6	0	0	6
urokinase plasminogen activator surface receptor precursor	6	0	0	6
geminin	17	0	0	17
DNA polymerase kappa isoform 1	8	0	0	8
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	1	0	1
Transthyretin	0	1	2	3
Fatty acid-binding protein, intestinal	0	2	2	4
Fatty acid-binding protein, adipocyte	0	1	2	3
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	2	1	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	4	0	0	4
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
RAR-related orphan receptor gamma	19	0	0	19
GLI family zinc finger 3	17	0	0	17
AR protein	19	0	0	19
aldehyde dehydrogenase 1 family, member A1	14	0	0	14
retinoic acid nuclear receptor alpha variant 1	16	0	0	16
retinoid X nuclear receptor alpha	13	0	0	13
estrogen nuclear receptor alpha	25	0	0	25
peroxisome proliferator-activated receptor delta	10	0	0	10
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	11	0	0	11
activating transcription factor 6	6	0	0	6
v-jun sarcoma virus 17 oncogene homolog (avian)	15	0	0	15
Histone H2A.x	8	0	0	8
thyroid hormone receptor beta isoform a	9	0	0	9
heat shock protein beta-1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 1	16	0	0	16
lamin isoform A-delta10	14	0	0	14
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Glutamate receptor 2	10	0	0	10
ATAD5 protein, partial	8	0	0	8
GLS protein	7	0	0	7
Microtubule-associated protein tau	4	0	0	4
Smad3	5	0	0	5
thyroid stimulating hormone receptor	10	0	0	10
nuclear receptor subfamily 1, group I, member 3	12	0	0	12
progesterone receptor	12	0	0	12
EWS/FLI fusion protein	9	0	0	9
estrogen-related nuclear receptor alpha	19	0	0	19
peroxisome proliferator activated receptor gamma	11	0	0	11
aryl hydrocarbon receptor	12	0	0	12
chromobox protein homolog 1	14	0	0	14
thyroid hormone receptor beta isoform 2	14	0	0	14
peripheral myelin protein 22	6	0	0	6
cytochrome P450 3A4 isoform 1	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	5	1	0	6
ATP-binding cassette sub-family C member 3	0	17	0	17
Multidrug resistance-associated protein 4	0	17	0	18
Solute carrier family 22 member 6	0	4	0	4
Carbonic anhydrase 12	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	3	0	3
Bile salt export pump	0	21	0	21
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	5	0	5
Carbonic anhydrase 2	0	6	0	6
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	2	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 3	0	2	0	2
Cytochrome P450 3A4	0	5	0	6
Cytochrome P450 2D6	0	5	0	5
Cytochrome P450 2C9	0	10	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	5	1	0	6
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	5	1	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	5	1	0	6
UDP-glucuronosyltransferase 1-6	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	5	1	0	6
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 6	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	5	1	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	5	1	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	5	1	0	6
Carbonic anhydrase 5A, mitochondrial	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	4
Carbonic anhydrase 7	0	3	0	3
Nuclear receptor ROR-gamma	6	0	0	6
Cytochrome P450 2J2	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-1	5	1	0	6
Gamma-aminobutyric acid receptor subunit beta-3	5	1	0	6
Gamma-aminobutyric acid receptor subunit beta-2	5	1	0	6
Carbonic anhydrase 9	0	2	0	2
GABA theta subunit	5	1	0	6
Canalicular multispecific organic anion transporter 1	0	16	0	16
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	5	1	0	6
Carbonic anhydrase 14	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	2	0	2
toxin B	0	0	0	1
Telomerase reverse transcriptase	0	1	0	1
Amyloid-beta precursor protein	1	3	0	4
Reverse transcriptase/RNaseH	0	1	0	1
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Aminoglycoside 3'-phosphotransferase	0	0	0	1
ATP-dependent phosphofructokinase	9	0	0	9
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	11	0	0	11
Chain A, Beta-lactamase	7	0	0	7
Chain A, 2-oxoglutarate Oxygenase	5	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
apical membrane antigen 1, AMA1	4	0	0	4
Beta-lactamase	0	0	0	3
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	4
Beta-lactamase	0	0	0	4
Kappa-type opioid receptor	0	3	1	6
Solute carrier family 15 member 1	0	5	0	5
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	4
Solute carrier family 15 member 2	0	4	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	4	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Cruzipain	4	0	0	4
Beta-lactamase	0	0	0	2
farnesoid X nuclear receptor	11	0	0	11
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	1	4
Metallo-beta-lactamase VIM-11	0	0	0	3
euchromatic histone-lysine N-methyltransferase 2	18	0	0	18
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
DNA polymerase beta	3	0	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	1
Spike glycoprotein	6	0	1	7
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	1	0	4
Efflux transporter	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	3
Beta-lactamase	0	0	0	3
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	3	0	3
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	1	4
10 kDa chaperonin	0	3	0	3
Metallo-b-lactamase	0	0	0	4
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	4
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	1	5
Beta-lactamase VIM-1	0	1	0	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
phosphopantetheinyl transferase	3	0	0	3
NFKB1 protein, partial	3	0	0	3
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	4	0	0	4
muscarinic acetylcholine receptor M1	5	0	0	5
lethal factor (plasmid)	9	0	0	9
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Stimulator of interferon genes protein	0	0	1	1
Stimulator of interferon genes protein	0	0	2	2
RocR	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
Beta-lactamase	0	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	1	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 6	0	2	0	2
Beta-lactamase	0	0	0	3
Solute carrier family 22 member 7	0	1	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase IMP-1	0	0	0	3
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	2	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 22 member 11	0	1	0	2
Solute carrier family 22 member 8	0	2	0	3
Solute carrier family 22 member 7	0	1	0	2
interleukin 8	7	0	0	7
pregnane X nuclear receptor	16	0	0	16
G	7	0	0	7
cytochrome P450 2D6	6	0	0	6
vitamin D (1,25- dihydroxyvitamin D3) receptor	10	0	0	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
streptokinase A precursor	0	0	6	6
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	7	0	0	7
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
Cellular tumor antigen p53	15	0	0	15
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
50S ribosomal protein L36 2	0	3	1	4
Inositol hexakisphosphate kinase 1	7	0	0	7
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	7	0	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	8	0	8
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
cytochrome P450 2C9 precursor	4	0	0	4
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	1	0	3
DNA gyrase subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	0	4
DNA gyrase subunit A	0	1	0	2
Cytochrome P450 2C19	0	1	0	1
Multidrug resistance protein MdtK	0	0	1	1
Histamine H2 receptor	5	0	0	5
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	2
Potassium voltage-gated channel subfamily H member 2	0	4	0	5
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	3	0	3
Chain A, Ferritin light chain	1	0	0	1
Luciferase	6	0	0	6
endonuclease IV	4	0	0	4
PAX8	0	0	0	1
pregnane X receptor	8	0	0	8
Fumarate hydratase	3	0	0	3
PPM1D protein	3	0	0	3
Thrombopoietin	2	0	0	2
estrogen receptor 2 (ER beta)	8	0	0	8
cytochrome P450 family 3 subfamily A polypeptide 4	8	0	0	8
glucocorticoid receptor [Homo sapiens]	15	0	0	15
polyprotein	3	0	0	3
67.9K protein	6	0	0	6
glucocerebrosidase	2	0	0	2
IDH1	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
cytochrome P450 2D6 isoform 1	4	0	0	4
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	3	0	0	3
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	5	0	0	5
caspase-1 isoform alpha precursor	1	0	0	1
neuropeptide S receptor isoform A	1	0	0	1
Solute carrier family 22 member 3	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	4	1	6
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	2	0	2
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	8	0	0	8
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
Phosphodiesterase	0	1	0	1
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
thyroid stimulating hormone receptor	8	0	0	8
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	9	0	0	9
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
mitogen-activated protein kinase 1	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
Androgen receptor	0	4	0	4
dopamine D1 receptor	4	0	0	4
regulator of G-protein signaling 4	4	0	0	4
arylsulfatase A	5	0	0	5
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
M-phase phosphoprotein 8	2	0	0	2
Eyes absent homolog 2	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Albumin	0	2	3	5
60 kDa chaperonin	0	1	0	1
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
Cytochrome P450 1B1	0	3	0	3
Lanosterol 14-alpha demethylase	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	1	0	0	1
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
acetylcholinesterase	5	0	0	5
glp-1 receptor, partial	2	0	0	2
Skn7p	0	0	0	1
nonstructural protein 1	2	0	0	2
peripheral myelin protein 22 isoform 1	3	0	0	3
hemoglobin subunit beta	1	0	0	1
huntingtin isoform 2	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
Vpr	1	0	0	1
survival motor neuron protein isoform d	5	0	0	5
Solute carrier family 22 member 8	0	1	0	3
Epidermal growth factor receptor	0	1	0	1
Thymidylate synthase	0	1	0	1
Aromatase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Hsf1 protein	0	0	1	1
Carbonic anhydrase	0	1	0	1
Delta-type opioid receptor	0	3	1	5
Delta-type opioid receptor	0	3	2	5
Mu-type opioid receptor	0	3	2	5
Mu-type opioid receptor	0	4	1	5
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
Fatty acid-binding protein, liver	0	2	0	2
Caspase-1	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
Chain B, Transthyretin	0	0	1	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein kinase II subunit alpha	0	1	0	1
Chain A, Casein Kinase Ii Subunit Alpha	0	1	0	1
Genome polyprotein	0	1	0	1
histidine kinase	0	1	0	1
BRCA1	1	0	0	1
15-lipoxygenase, partial	2	0	0	2
WRN	2	0	0	2
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Neuraminidase	0	2	0	2
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
P53	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Bloom syndrome protein isoform 1	2	0	0	2
lysosomal alpha-glucosidase preproprotein	2	0	0	2
galactokinase	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
nuclear receptor ROR-gamma isoform 1	2	0	0	2
POsterior Segregation	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Aldo-keto reductase family 1 member B10	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-1	0	1	0	1
Cationic trypsin	0	1	0	1
Interstitial collagenase	0	1	0	1
Glucocorticoid receptor	0	6	2	14
Integrin beta-3	2	0	0	2
Cyclin-dependent kinase 1	0	1	0	1
Chemotaxis protein CheA	0	1	0	1
Procathepsin L	0	0	1	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Tyrosine-protein kinase Yes	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Neutrophil elastase	0	2	0	2
72 kDa type IV collagenase	0	2	0	2
Stromelysin-1	0	3	0	3
Integrin alpha-IIb	2	0	0	2
Poly [ADP-ribose] polymerase 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	2	1	3
Alpha-amylase 1A	0	1	0	1
Androgen receptor	0	2	0	3
Sialidase	0	1	0	1
Fatty acid synthase	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Tyrosinase	0	1	0	1
Matrix metalloproteinase-9	0	2	0	2
Urease subunit alpha	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Casein kinase II subunit alpha'	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Acetylcholinesterase	0	4	0	4
Sodium-dependent noradrenaline transporter	0	2	1	3
Sodium-dependent dopamine transporter	0	0	1	1
Cruzipain	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Dipeptidyl peptidase 4	0	3	0	3
Proteasome subunit beta type-5	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Substance-P receptor	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Alpha-synuclein	0	2	0	2
Macrophage metalloelastase	0	1	0	1
Homeobox protein Nkx-2.5	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	0	2
Fatty acid synthase	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
Urease subunit beta	0	2	0	2
Xanthine dehydrogenase/oxidase	0	2	0	3
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Cyclin homolog	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Transcription factor GATA-4	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Substance-K receptor	0	1	0	1
Protein polybromo-1	0	0	1	1
Casein kinase II subunit alpha 3	0	1	0	1
Inositol polyphosphate multikinase	0	1	0	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	2	0	2
Aurora kinase B	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
NADPH oxidase 4	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
Sialidase-2	0	1	0	1
phosphoglycerate kinase	2	0	0	2
M1-family alanyl aminopeptidase	0	1	0	1
large T antigen	0	1	1	2
Solute carrier family 22 member 1	0	5	0	6
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
BlaVIM-1	0	0	0	2
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
5-hydroxytryptamine receptor 3E	0	0	1	1
D(1A) dopamine receptor	2	0	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
5-hydroxytryptamine receptor 3B	0	0	1	1
Albumin	0	0	1	1
Myeloperoxidase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
Alpha-2A adrenergic receptor	0	5	0	5
D(2) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-1B adrenergic receptor	0	3	0	3
D	0	1	0	1
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
D(3) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Alpha-1A adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 7	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	2
5-hydroxytryptamine receptor 3D	0	0	1	1
5-hydroxytryptamine receptor 3C	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Histidine decarboxylase	0	0	1	1
Adenosine receptor A1	0	1	0	1
Kappa-type opioid receptor	0	1	0	2
Kappa-type opioid receptor	0	1	2	3
Mu-type opioid receptor	0	2	1	4
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	2	5
Mu-type opioid receptor	0	1	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
Valosin-containing protein	0	1	0	1
thioredoxin glutathione reductase	2	0	0	2
transcriptional regulator ERG isoform 3	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Tumor necrosis factor	0	1	0	1
Cholinesterase	0	1	0	1
Adenosine receptor A2b	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Inositol monophosphatase 1	1	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chitotriosidase-1	0	2	1	3
Endochitinase B1	0	2	1	3
serine-protein kinase ATM isoform a	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
GALC protein	1	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Dihydrofolate reductase	0	2	0	2
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Dihydrofolate reductase	0	4	1	6
Bifunctional dihydrofolate reductase-thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	4	0	5
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Trace amine-associated receptor 5	0	0	2	2
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	2	0	3
N	0	1	0	1
NPYLR7B	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
tumor susceptibility gene 101 protein	1	0	0	1
Glutathione reductase, mitochondrial	0	1	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	0	1	1
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
Trypanothione reductase	0	2	0	2
D(1A) dopamine receptor	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Cholinesterase	0	1	0	1
Aldehyde oxidase	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Acetylcholinesterase	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Neutrophil collagenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
caspase-3	1	0	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium-dependent serotonin transporter	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (150)

Protein Targets (847)

Borrelia hermsii Infection

Synonyms(5)

Research Excerpts

Overview

Treatment

Research

Studies (150)

Drugs Studied (95)

Protein Targets (847)