Page last updated: 2024-08-05 12:14:27
timolol
1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.
ChEBI ID: 39465
Members (1)
Member | Definition | Role |
timolol | The (S)-(-) (more active) enantiomer of timolol. A beta-adrenergic antagonist, both the hemihydrate and the maleate salt are used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine. | (S)-timolol (anhydrous) |
Research
Studies (3,612)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
pre-1990 | 1,297 (35.91) | 18.7374 |
1990's | 679 (18.80) | 18.2507 |
2000's | 750 (20.76) | 29.6817 |
2010's | 672 (18.60) | 24.3611 |
2020's | 214 (5.92) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
Trials | 1,198 (30.47%) | 5.53% |
Reviews | 249 (6.33%) | 6.00% |
Case Studies | 396 (10.07%) | 4.05% |
Observational | 14 (0.36%) | 0.25% |
Other | 2,075 (52.77%) | 84.16% |