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timolol

1,2,5-Thiadiazole substituted at the 3 position by a 3-(tert-butylamino)-2-hydroxypropoxy group and at the 4 position by a morpholin-4-yl group. The (S)-(-) enantiomer, also known as timolol, is a beta-adrenergic antagonist and is used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.

ChEBI ID: 39465

Members (1)

MemberDefinitionRole
timololThe (S)-(-) (more active) enantiomer of timolol. A beta-adrenergic antagonist, both the hemihydrate and the maleate salt are used in the mangement of glaucoma, hypertension, angina pectoris and myocardial infarction, and for the prevention of migraine.(S)-timolol (anhydrous)

Research

Studies (3,612)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19901,297 (35.91)18.7374
1990's679 (18.80)18.2507
2000's750 (20.76)29.6817
2010's672 (18.60)24.3611
2020's214 (5.92)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,198 (30.47%)5.53%
Reviews249 (6.33%)6.00%
Case Studies396 (10.07%)4.05%
Observational14 (0.36%)0.25%
Other2,075 (52.77%)84.16%