An acetylenic and an olefinic compound containing a carbon chain that contains a carbon-carbon double bond and a carbon-carbon triple bond.
ChEBI ID: 59831
| Member | Definition | Role |
|---|---|---|
| beraprost | An organic heterotricyclic compound that is (3aS,8bS)-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan in which the hydrogens at positions 1R, 2R and 5 are replaced by (3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl, hydroxy and 3-carboxypropyl groups, respectively. It is a prostaglandin receptor agonist which is approved to treat pulmonary arterial hypertension in Asia. | beraprost |
| terbinafine | A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. | terbinafine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 69 (2.89) | 18.7374 |
| 1990's | 544 (22.79) | 18.2507 |
| 2000's | 774 (32.43) | 29.6817 |
| 2010's | 717 (30.04) | 24.3611 |
| 2020's | 283 (11.86) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 341 (13.26%) | 5.53% |
| Reviews | 334 (12.99%) | 6.00% |
| Case Studies | 616 (23.96%) | 4.05% |
| Observational | 6 (0.23%) | 0.25% |
| Other | 1,274 (49.55%) | 84.16% |