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cholestanoid

Any steroid based on a cholestane skeleton and its derivatives.

ChEBI ID: 50401

Members (25)

MemberDefinitionRole
19-hydroxycholesterol19-Hydroxycholesterol
20,22-dihydroxycholesterolAn oxysterol that is cholesterol substituted by hydroxy groups at positions 20 and 22 (the 20R,22R-stereoisomer).(20R,22R)-20,22-dihydroxycholesterol
22-ketocholesterolA 3beta-sterol that is cholesterol carrying an oxo group at position 22.22-ketocholesterol
24,25-epoxycholesterolA 3beta-hydroxy-Delta(5)-steroid that is desmosterol in which the double bond at position 24-25 has been oxidised to the corresponding epoxide (the 24S diastereoisomer). It is an oxysterol agonist of the liver X receptor.24(S),25-epoxycholesterol
3-hydroxy-5-cholestenoic acidA steroid acid resulting from the oxidation of one of the terminal methyl groups of cholesterol to the corresponding aldehyde.3beta-hydroxycholest-5-en-26-oic acid
4,4-dimethylcholesta-8,14-dien-3-olA cholestanoid that is 5alpha-cholesta-8,14-dien-3beta-ol bearing two additional methyl substituents at position 4.4,4-dimethyl-8,14-cholestadien-3beta-ol
4,6-cholestadien-3-onecholest-4,6-dien-3-one
5,22-cholestadien-3beta-olcholesta-5,22E-dien-3-ol
6-ketocholestanol6-Oxocholestanol
7 alpha-hydroxy-4-cholesten-3-oneA cholestanoid consisting of a cholesterol core having an oxo group at the 3-position, a C=C bond at the 4,5-position and an alpha-hydroxy group at the 7-position.7alpha-hydroxycholest-4-en-3-one
7-aminocholesterolA 3beta-sterol that is cholesterol substituted at position 7 by an amino group.7-aminocholesterol
7-dehydrocholesterolcholesta-5,7-dien-3beta-ol
7-ketocholesterolA cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.7-ketocholesterol
cholest-4-en-3-oneA cholestanoid that is cholest-4-ene substituted by an oxo group at position 3.cholest-4-en-3-one
cholest-5-en-3-oneA 3-oxo Delta(5)-steroid that is cholesterol in which the alcoholic hydroxy group has been oxidised to the corresponding ketone.cholest-5-en-3-one
cholestane-3,7,12,25-tetrolCholestane-3,7,12,25-tetrol
cholestanol(3S,5S)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
cholestanol, (3alpha, 5beta)-isomerEpi-coprostanol
coprostanone(5R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
dafachronic acidA cholestanoid that is (5alpha)-cholestan-26-oic acid in which the hydrogens at position 3 are replaced by an oxo group.(5alpha)-3-oxocholestan-26-oic acid
desmosterolA cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.desmosterol
lathosterolA cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3.5alpha-cholest-7-en-3beta-ol
ys 64Cholestan-6-oxo-3,5-diol
zymostenolA cholestanoid that is 5alpha-cholestane substituted by a beta-hydroxy group at position 3.5alpha-cholest-8-en-3beta-ol
zymosterolzymosterol

Research

Studies (2,488)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990567 (22.79)18.7374
1990's451 (18.13)18.2507
2000's605 (24.32)29.6817
2010's714 (28.70)24.3611
2020's151 (6.07)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials171 (6.12%)5.53%
Reviews137 (4.91%)6.00%
Case Studies113 (4.05%)4.05%
Observational6 (0.21%)0.25%
Other2,365 (84.71%)84.16%