Any compound that has anti-asthmatic effects.
| Member | Definition | Class |
|---|
| betamethasone | | betamethasone |
| davidigenin | A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', and 4' respectively. | davidigenin |
| ici 204,219 | | zafirlukast |
| jte 013 | A semicarbazide derivative that is semicarbazide in which the amino group at position 2 is replaced by a [1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl]amino group and the amino group adjacent to the carbonyl is replaced by a (2,6-dichloropyridin-4-yl)amino group. It is a potent S1P2 antagonist (IC50 = 17.6 nM). | JTE-013 |
| khellin | A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. | khellin |
| matairesinol | A lignan that is gamma-butyrolactone in which the 3 and 4 positions are substituted by 4-hydroxy-3-methoxybenzyl groups (the 3R,4R-diastereomer). | (-)-matairesinol |
| oridonin | An organic heteropentacyclic compound and ent-kaurane diterpenoid with formula C20H28O6 isolated from the leaves of the medicinal herb Rabdosia rubescens. | oridonin |
| picrinine | A natural product with formula C20H22N2O3 that is the member of the akuammiline family of alkaloids, first isolated in 1965 from the leaves of Alstonia scholaris. | picrinine |
| schizandrin b | An organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis. | (+)-schisandrin B; Deoxygomisin A |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 21.1546 | 1 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 10.6822 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 0.0089 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 2.5308 | 11 | 19 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 13.3953 | 2 | 6 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 8.4284 | 2 | 3 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 0.2512 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 12.3834 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 21.5138 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 7.5060 | 2 | 6 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 7.3954 | 2 | 4 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.0146 | 1 | 2 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 37.6858 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 6.0393 | 6 | 9 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 13.3332 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 64.8601 | 2 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 19.2293 | 1 | 3 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 20.5627 | 4 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 33.4889 | 2 | 2 |
| G | Vesicular stomatitis virus | Potency | 12.3834 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| GALC protein | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 7.5060 | 1 | 4 |
| geminin | Homo sapiens (human) | Potency | 21.1360 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 15.6058 | 2 | 5 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 4.6999 | 4 | 9 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.0841 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 9.9276 | 1 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 12.3834 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 23.9145 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 3.6626 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 12.3834 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 12.3834 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 18.1227 | 3 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 26.6514 | 2 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 29.0000 | 3 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 0.0108 | 2 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 30.1065 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 13.5346 | 2 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 14.1254 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 12.8962 | 3 | 6 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 5.4897 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 8.0250 | 3 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 33.4889 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 22.3832 | 2 | 3 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 17.7828 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 10.0073 | 3 | 4 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 26.8325 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 12.5893 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 1.2589 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.1267 | 2 | 3 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 25.6204 | 2 | 2 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 4.3386 | 2 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 36.2530 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.0841 | 1 | 1 |