Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
| Member | Definition | Class |
|---|
| 2-hydroxybutyric acid | A hydroxybutyric acid having a single hydroxyl group located at position 2; urinary secretion of 2-hydroxybutyric acid is increased with alcohol ingestion or vigorous physical exercise and is associated with lactic acidosis and ketoacidosis in humans and diabetes in animals. | 2-hydroxybutyric acid |
| 2-keto-4-methylvalerate | A 2-oxo monocarboxylic acid that is pentanoic acid (valeric acid) substituted with a keto group at C-2 and a methyl group at C-4. A metabolite that has been found to accumulate in maple syrup urine disease. | 4-methyl-2-oxopentanoic acid |
| 2-palmitoylglycerol | A 2-monoglyceride where the acyl group is hexadecanoyl (palmitoyl). | 2-palmitoylglycerol |
| 3-mercaptopropionic acid | A mercaptopropanoic acid that is propanoic acid carrying a sulfanyl group at position 3. | 3-mercaptopropanoic acid |
| 3-phosphoglycerate | A monophosphoglyceric acid having the phospho group at the 3-position. It is an intermediate in metabolic pathways like glycolysis and calvin cycle. | 3-phosphoglyceric acid |
| 4-hydroxybenzoic acid | A monohydroxybenzoic acid that is benzoic acid carrying a hydroxy substituent at C-4 of the benzene ring. | 4-hydroxybenzoic acid |
| 5'-methylthioadenosine | Adenosine with the hydroxy group at C-5' substituted with a methylthio (methylsulfanyl) group. | 5'-S-methyl-5'-thioadenosine |
| 6-bromo-3-(bromomethyl)-7-methyl-2,3,7-trichloro-1-octene | | (+)-halomon |
| acetohydroxamic acid | A member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group. | acetohydroxamic acid; N-hydroxyacetimidic acid |
| adonixanthin | A carotenone that consists of beta,beta-caroten-4-one bearing two hydroxy substituents at positions 3 and 3' (the 3S,3'R diastereomer). | adonixanthin |
| alpha-glycerophosphoric acid | A glycerol monophosphate having the phosphate group located at position 1. | glycerol 1-phosphate |
| altritol | A hexitol that is hexane-1,2,3,4,5,6-hexol having (2R,3R,4S,5R) configuration; the D-enantiomer of altritol. | D-altritol |
| aplysiatoxin | The parent member of the class of aplysiatoxins. It is a cyanotoxin produced by several species of freshwater and marine cyanobacteria, as well as algae and molluscs. | aplysiatoxin |
| benzoic acid | A compound comprising a benzene ring core carrying a carboxylic acid substituent. | benzoic acid |
| beta-aminoglutaric acid | A 1,5-dicarboxylic acid compound having a 3-amino substituent. It has been isolated from the extracts of the algae, Chondria armata. | isoglutamic acid |
| brassicasterol | An 3beta-sterol that is (22E)-ergosta-5,22-diene substituted by a hydroxy group at position 3beta. It is a phytosterol found in marine algae, fish, and rapeseed oil. | brassicasterol |
| butyl stearate | A fatty acid ester that is the butyl ester of stearic acid. | butyl octadecanoate |
| cetyl alcohol | A long-chain primary fatty alcohol that is hexadecane substituted by a hydroxy group at position 1. | hexadecan-1-ol |
| d-2-hydroxyglutarate | The (R)-enantiomer of 2-hydroxyglutaric acid. | (R)-2-hydroxyglutaric acid |
| d-alpha tocopherol | An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. | (R,R,R)-alpha-tocopherol |
| debromoaplysiatoxin | A member of the class of aplysiatoxins that has the structure of the parent aplysiatoxin, but is lacking the bromo substituent on the benzene ring at the position para to the phenolic hydroxy group. It is a cyanotoxin produced by several species of freshwater and marine cyanobacteria, as well as algae and molluscs. | debromoaplysiatoxin |
| decanoic acid | A C10, straight-chain saturated fatty acid. | decanoic acid |
| dimethyl sulfide | A methyl sulfide in which the sulfur atom is substituted by two methyl groups. It is produced naturally by some marine algae. | dimethyl sulfide |
| dipropylenetriame | | bis(3-aminopropyl)amine |
| docosahexaenoate | A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19. | all-cis-docosa-4,7,10,13,16,19-hexaenoic acid |
| docosapentaenoic acid | The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 7-, 10-, 13-, 16- and 19-positions. | (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid |
| domoic acid | An L-proline derivative that is L-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,4-dien-2-yl group at position 4. It is produced by the diatomic algal Pseudo-nitzschia. It is an analogue of kainic acid and a neurotoxin which causes amnesic shellfish poisoning (ASP). | domoic acid |
| ethylene dibromide | A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae. | 1,2-dibromoethane |
| gamma-tocopherol | A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils. | gamma-tocopherol |
| glucuronic acid | A D-glucuronic acid in cyclic pyranose form. | D-glucopyranuronic acid |
| glycerol | A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups. | glycerol |
| glycerol 1-stearate | A 1-monoglyceride that has stearoyl as the acyl group. | 1-monostearoylglycerol; rac-1-monostearoylglycerol |
| guanine | A 2-aminopurine carrying a 6-oxo substituent. | guanine |
| harmalol | A harmala alkaloid in which the harman skeleton is hydroxy-substituted at C-7 and has been reduced across the 3,4 bond. | harmalol |
| histidine | The L-enantiomer of the amino acid histidine. | L-histidine zwitterion; L-histidine |
| homoserine | The L-enantiomer of homoserine. | L-homoserine zwitterion; L-homoserine |
| hydroxylamine | The simplest hydroxylamine, consisting of ammonia bearing a hydroxy substituent. It is an intermediate in the biological nitrification by microbes like bacteria. | hydroxylamine |
| isoleucine | The L-enantiomer of isoleucine. | L-isoleucine zwitterion; L-isoleucine |
| isonicotinic acid | A pyridinemonocarboxylic acid in which the carboxy group is at position 4 of the pyridine ring. | isonicotinic acid |
| lactic acid | A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. | 2-hydroxypropanoic acid |
| lauric acid | A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil. | dodecanoic acid |
| leucine | The L-enantiomer of leucine. | L-leucine zwitterion; L-leucine |
| linoleic acid | An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry. | linoleic acid |
| lysine | An L-alpha-amino acid; the L-isomer of lysine. | L-Lysine zwitterion; L-lysine |
| maleic acid | A butenedioic acid in which the double bond has cis- (Z)-configuration. | maleic acid |
| margaric acid | A C17 saturated fatty acid and trace component of fats in ruminants. | heptadecanoic acid |
| methyl bromide | A one-carbon compound in which the carbon is attached by single bonds to three hydrogen atoms and one bromine atom. It is produced naturally by marine algae. | bromomethane |
| methylene bromide | A member of the class of bromomethanes that is methane substituted by two bromo groups. It is produced by marine algae. | dibromomethane |
| methylphosphate | A monoalkyl phosphate having methyl as the alkyl group. | methyl dihydrogen phosphate |
| myristic acid | A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat. | tetradecanoic acid |
| n(1)-methylnicotinamide | A pyridinium ion comprising nicotinamide having a methyl group at the 1-position. It is a metabolite of nicotinamide which was initially considered to be biologically inactive but has emerged as an anti-thrombotic and anti-inflammatory agent. | 1-methylnicotinamide |
| ornithine | An optically active form of ornithine having L-configuration. | L-ornithine |
| oxalic acid | An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2. | oxalic acid |
| palmitic acid | A straight-chain, sixteen-carbon, saturated long-chain fatty acid. | hexadecanoic acid |
| palmitoleic acid | A hexadec-9-enoic acid in which the double bond at position C-9 has cis configuration. | palmitoleic acid |
| pelargonic acid | A C9 straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium. Has antifungal properties, and is also used as a herbicide as well as in the preparation of plasticisers and lacquers. | nonanoic acid |
| pentadecanoic acid | A straight-chain saturated fatty acid containing fifteen-carbon atoms. | pentadecanoic acid |
| phenylalanine | The L-enantiomer of phenylalanine. | L-phenylalanine zwitterion; L-phenylalanine |
| phloroglucinol | A benzenetriol with hydroxy groups at position 1, 3 and 5. | phloroglucinol |
| phosphoric acid | A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. | phosphoric acid |
| phosphorylethanolamine | The ethanolamine mono-ester of phosphoric acid, and a metabolite of phospholipid metabolism. This phosphomonoester shows strong structural similarity to the inhibitory neurotransmitter GABA, and is decreased in post-mortem Alzheimer's disease brain. | O-phosphoethanolamine |
| proline | Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. | L-proline zwitterion; L-proline |
| pyrrolidonecarboxylic acid | An optically active form of 5-oxoproline having L-configuration. | 5-oxo-L-proline |
| racemethionine | A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. | methionine zwitterion; methionine |
| salicylic acid | A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. | salicylic acid |
| serine | The L-enantiomer of serine. | L-serine zwitterion; L-serine |
| sodium benzoate | An organic sodium salt resulting from the replacement of the proton from the carboxy group of benzoic acid by a sodium ion. | sodium benzoate |
| stearic acid | A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics. | octadecanoic acid |
| stearyl alcohol | A long-chain primary fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of 18 carbon atoms. | octadecan-1-ol |
| sucrose | A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose. | sucrose |
| threonine | An optically active form of threonine having L-configuration. | L-threonine zwitterion; L-threonine |
| tramiprosate | An amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid. | 3-aminopropanesulfonic acid zwitterion; 3-aminopropanesulfonic acid |
| trans-phytol | A diterpenoid that is hexadec-2-en-1-ol substituted by methyl groups at positions 3, 7, 11 and 15. | phytol |
| valine | The L-enantiomer of valine. | L-valine zwitterion; L-valine |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 26.0501 | 1 | 4 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 17.5195 | 1 | 3 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 58.5346 | 3 | 10 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 223.8720 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 35.1328 | 2 | 7 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 29.9590 | 1 | 10 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 28.1838 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 18.9257 | 12 | 49 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 61.1306 | 1 | 1 |
| arylsulfatase A | Homo sapiens (human) | Potency | 37.9330 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.0348 | 2 | 3 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.0120 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 60.1373 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 60.1373 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 37.4712 | 2 | 16 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 1.6816 | 2 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 34.2102 | 1 | 5 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 50.1187 | 1 | 1 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 21.7234 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 39.8107 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 34.0908 | 1 | 4 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 72.6796 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 25.5641 | 1 | 4 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 17.7407 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 19.4878 | 1 | 4 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 34.0908 | 1 | 4 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 61.9992 | 2 | 4 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 3.3786 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 6.1683 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 17.4566 | 2 | 6 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 30.5252 | 1 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 46.9177 | 1 | 6 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 21.1360 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 12.2430 | 1 | 6 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 26.2278 | 11 | 72 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 42.1683 | 3 | 15 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 30.7644 | 6 | 33 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 19.3748 | 1 | 7 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 33.2087 | 4 | 8 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 54.2184 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 3.3786 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 17.4566 | 1 | 3 |
| geminin | Homo sapiens (human) | Potency | 13.5880 | 2 | 13 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 19.4479 | 2 | 18 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 9.0532 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 30.3001 | 1 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 25.7696 | 3 | 17 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 55.9820 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 1.4581 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 45.8009 | 2 | 9 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 23.7358 | 1 | 4 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 26.3849 | 1 | 6 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 3.3786 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 60.8142 | 2 | 4 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 36.1264 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 3.3786 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 25.7903 | 2 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0165 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0165 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 3.3540 | 2 | 2 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.1725 | 1 | 7 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 13.1805 | 1 | 5 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 64.8281 | 3 | 14 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 13.7112 | 2 | 6 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 6.6640 | 2 | 3 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 15.8489 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 40.3722 | 4 | 16 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 0.0141 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 31.6859 | 1 | 6 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 60.2667 | 1 | 3 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 31.6228 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 14.1254 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 37.9692 | 2 | 5 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 55.7562 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 7.9496 | 1 | 5 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 31.8311 | 5 | 19 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 31.5381 | 1 | 5 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 45.0502 | 5 | 20 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 66.9654 | 1 | 6 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 23.7358 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 30.7705 | 2 | 6 |
| progesterone receptor | Homo sapiens (human) | Potency | 23.6778 | 2 | 7 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 30.6230 | 1 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 26.8799 | 2 | 10 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 21.1923 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 43.5706 | 3 | 26 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 46.2258 | 4 | 27 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 29.9349 | 1 | 1 |
| Single-stranded DNA cytosine deaminase | Homo sapiens (human) | Potency | 49.2215 | 2 | 4 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 36.6830 | 2 | 8 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 36.6830 | 2 | 8 |
| Smad3 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 36.1264 | 2 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 23.4451 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 18.1863 | 1 | 2 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 4.8102 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 18.4809 | 2 | 12 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 26.0051 | 2 | 3 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 53.2308 | 3 | 22 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 20.2227 | 2 | 7 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 20.4091 | 3 | 17 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 12.5893 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 42.4609 | 2 | 7 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 28.9171 | 2 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 31.5077 | 4 | 8 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 54.6066 | 1 | 5 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 55.9820 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 58.0000 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Ki | 27,000.0000 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 5A | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | IC50 | 80.2000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 58.0000 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 15,000.0000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 7.2362 | 3 | 4 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 346.0000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | Ki | 4.0100 | 2 | 2 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 20.3650 | 3 | 4 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 3.3600 | 6 | 6 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 2.7460 | 4 | 5 |
| Adenosine receptor A2b | Homo sapiens (human) | Ki | 11.0500 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 71.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 0.6800 | 1 | 1 |
| Albumin | Homo sapiens (human) | Ki | 5,888,440,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | IC50 | 0.6900 | 2 | 2 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Homo sapiens (human) | IC50 | 77.5250 | 3 | 4 |
| Alkaline phosphatase, tissue-nonspecific isozyme | Bos taurus (cattle) | IC50 | 80.2033 | 3 | 3 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 300.0000 | 1 | 3 |
| Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Amino acid transporter | Rattus norvegicus (Norway rat) | IC50 | 1,050.7250 | 2 | 4 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Angiotensin-converting enzyme | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 32.6667 | 1 | 3 |
| Beta-lactamase | Klebsiella pneumoniae | IC50 | 2,000.0000 | 1 | 1 |
| Beta-lactamase | Pseudomonas aeruginosa | Ki | 0.1800 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 36.4700 | 1 | 1 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | Escherichia coli K-12 | Ki | 45,000.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 24.4000 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 166.2300 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 560.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 254.4092 | 8 | 37 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 209.8923 | 3 | 30 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 214.5897 | 3 | 30 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 212.2387 | 3 | 30 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 8.2600 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 205.2500 | 4 | 4 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 227.5972 | 10 | 39 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 262.1503 | 3 | 30 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 231.5961 | 4 | 31 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 450.8958 | 4 | 31 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 221.6510 | 3 | 30 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 278.2548 | 4 | 31 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 235.9693 | 3 | 30 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 4,744.7282 | 6 | 33 |
| Caspase-1 | Homo sapiens (human) | IC50 | 6.7600 | 1 | 1 |
| Catechol O-methyltransferase | Homo sapiens (human) | Ki | 5,400.0000 | 1 | 1 |
| Cationic amino acid transporter 3 | Homo sapiens (human) | IC50 | 158.0000 | 1 | 1 |
| Chain A, AMINOPEPTIDASE | Streptomyces griseus | Ki | 12,550.0000 | 1 | 4 |
| Chain A, Arginase 1 | Rattus norvegicus (Norway rat) | Ki | 1,650.0000 | 1 | 4 |
| Chain A, Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Ki | 0.8020 | 1 | 1 |
| Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE | Homo sapiens (human) | Ki | 253.0000 | 1 | 1 |
| Chain A, Leucine Aminopeptidase | Bos taurus (cattle) | Ki | 0.0600 | 1 | 1 |
| Chain A, Oxygen-insensitive Nad(p)h Nitroreductase | Enterobacter cloacae | Ki | 100.0000 | 1 | 1 |
| Chain A, Phosphoenolpyruvate-protein phosphotransferase | Escherichia coli | Ki | 280.0000 | 1 | 1 |
| Chain A, Phosphonopyruvate hydrolase | Variovorax sp. Pal2 | Ki | 17.0000 | 1 | 1 |
| Chain A, Proto-oncogene Tyrosine-protein Kinase Src | Homo sapiens (human) | IC50 | 40,000.0000 | 1 | 26 |
| Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE | Pseudomonas putida | Ki | 122.0000 | 1 | 12 |
| Chain A, Pyruvate kinase, M2 isozyme | Homo sapiens (human) | Ki | 24.0000 | 1 | 1 |
| Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | Pisum sativum (garden pea) | Ki | 36,600.0000 | 1 | 2 |
| Chain B, Oxygen-insensitive Nad(p)h Nitroreductase | Enterobacter cloacae | Ki | 100.0000 | 1 | 1 |
| Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE | Pseudomonas putida | Ki | 122.0000 | 1 | 12 |
| Cholinesterase | Equus caballus (horse) | IC50 | 0.0160 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 80.5000 | 1 | 2 |
| Cystathionine gamma-lyase | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 6.2920 | 1 | 1 |
| D-amino-acid oxidase | Homo sapiens (human) | IC50 | 62.1723 | 4 | 4 |
| D-amino-acid oxidase | Homo sapiens (human) | Ki | 22.2800 | 5 | 5 |
| D-aspartate oxidase | Homo sapiens (human) | IC50 | 10,000.0000 | 2 | 2 |
| Deoxyhypusine synthase | Rattus norvegicus (Norway rat) | IC50 | 41.0000 | 1 | 1 |
| Dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Dynamin-1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| E3 ubiquitin-protein ligase XIAP | Homo sapiens (human) | IC50 | 80.2000 | 1 | 1 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 1,500.0000 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | Ki | 1.6902 | 2 | 10 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | IC50 | 8.3075 | 4 | 4 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Ki | 3.5680 | 2 | 2 |
| Fatty acid-binding protein, heart | Homo sapiens (human) | IC50 | 1.0000 | 3 | 3 |
| Fatty acid-binding protein, heart | Homo sapiens (human) | Ki | 9.3000 | 1 | 1 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | IC50 | 1.7000 | 1 | 1 |
| Fatty acid-binding protein, liver | Mus musculus (house mouse) | Ki | 0.0700 | 1 | 1 |
| Fe(3+)-Zn(2+) purple acid phosphatase | Phaseolus vulgaris | Ki | 2,000.0000 | 1 | 1 |
| G-protein coupled receptor 84 | Homo sapiens (human) | Ki | 2.1967 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 414.0000 | 1 | 1 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | Ki | 4,400.0000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 61.2000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 54.6000 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 625.0000 | 2 | 2 |
| Hypoxia-inducible factor 1-alpha inhibitor | Homo sapiens (human) | IC50 | 189.0000 | 1 | 1 |
| Indolethylamine N-methyltransferase | Homo sapiens (human) | Ki | 700.0000 | 1 | 2 |
| Intestinal-type alkaline phosphatase | Bos taurus (cattle) | IC50 | 80.2060 | 5 | 5 |
| Intestinal-type alkaline phosphatase | Homo sapiens (human) | IC50 | 47.5500 | 3 | 4 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 88.6667 | 3 | 9 |
| Large neutral amino acids transporter small subunit 1 | Rattus norvegicus (Norway rat) | Ki | 55.0000 | 1 | 1 |
| Lethal factor | Bacillus anthracis | IC50 | 11,400.0000 | 1 | 1 |
| Lysine-specific demethylase 2A | Homo sapiens (human) | IC50 | 106.0000 | 1 | 1 |
| Lysine-specific demethylase 4A | Homo sapiens (human) | IC50 | 24.0000 | 1 | 1 |
| Lysine-specific demethylase 4C | Homo sapiens (human) | IC50 | 79.0000 | 1 | 1 |
| Monocarboxylate transporter 2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 54.0000 | 1 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 54.0000 | 1 | 1 |
| Neutral amino acid transporter A | Homo sapiens (human) | IC50 | 1,215.5000 | 1 | 2 |
| Neutral amino acid transporter B(0) | Homo sapiens (human) | IC50 | 5,411.0000 | 1 | 2 |
| Nicotinate phosphoribosyltransferase | Homo sapiens (human) | Ki | 0.0009 | 1 | 3 |
| Nociceptin receptor | Mus musculus (house mouse) | Ki | 20,000.0000 | 1 | 1 |
| Ornithine transcarbamylase, mitochondrial | Homo sapiens (human) | Ki | 12,666.6667 | 3 | 3 |
| Oxoeicosanoid receptor 1 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Peptide deformylase | Staphylococcus aureus subsp. aureus Mu50 | IC50 | 100.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Ki | 22.0000 | 1 | 1 |
| Phospholipase A-2-activating protein | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 332.3729 | 6 | 7 |
| Prolyl 4-hydroxylase | Paramecium bursaria Chlorella virus 1 | IC50 | 500.0000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 2,750.0000 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 184.3333 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 364.1667 | 1 | 6 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 350.6333 | 1 | 6 |
| Protein kinase C alpha type | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 40,000.0000 | 2 | 4 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 36,140.0000 | 1 | 5 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Purine nucleoside phosphorylase | Homo sapiens (human) | Ki | 5.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 200.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | Ki | 6.2920 | 1 | 1 |
| Ricin | Ricinus communis (castor bean) | IC50 | 900.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 8.3333 | 3 | 3 |
| Serine racemase | Homo sapiens (human) | IC50 | 10,000.0000 | 1 | 1 |
| Shiga toxin subunit A | Shigella dysenteriae | IC50 | 11.5000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 28.8138 | 1 | 4 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 280.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 198.4332 | 1 | 4 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 670.5000 | 2 | 2 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 1,020.0000 | 1 | 1 |
| Spermidine synthase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 159.0000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Homo sapiens (human) | IC50 | 1,000.0000 | 2 | 2 |
| Sterol O-acyltransferase 1 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Succinate-semialdehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Succinyl-diaminopimelate desuccinylase | Haemophilus influenzae Rd KW20 | IC50 | 1,000.0000 | 1 | 1 |
| Thiopurine S-methyltransferase | Homo sapiens (human) | IC50 | 1,737.8000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 9.7000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 80.5000 | 1 | 2 |
| Toll-like receptor 2 | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Toll-like receptor 2 | Mus musculus (house mouse) | IC50 | 118.1100 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| Trypsin | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 2 |
| Tyrosinase | Homo sapiens (human) | IC50 | 9.3500 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | Ki | 520.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 12.5250 | 2 | 4 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Ki | 19,400.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 7 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Tyrosine-protein phosphatase YopH | Yersinia pseudotuberculosis IP 32953 | Ki | 1,000.0000 | 1 | 1 |
| Ubiquitin-like domain-containing CTD phosphatase 1 | Homo sapiens (human) | IC50 | 66,000.0000 | 1 | 1 |
| Urease | Canavalia ensiformis (jack bean) | IC50 | 36.0000 | 4 | 4 |
| Urease subunit alpha | Escherichia coli | IC50 | 29.2000 | 1 | 1 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 61.0238 | 24 | 24 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 96.0000 | 1 | 1 |
| Urease subunit beta | Escherichia coli | IC50 | 29.2000 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 58.4596 | 23 | 23 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 96.0000 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori | IC50 | 17.2000 | 1 | 1 |
| Urease subunit gamma | Escherichia coli | IC50 | 29.2000 | 1 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | Mus musculus (house mouse) | Ki | 0.9786 | 1 | 2 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Ki | 100,000.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | KA | 113.0000 | 1 | 1 |
| 5-methylthioadenosine/S-adenosylhomocysteine deaminase | Thermotoga maritima MSB8 | Km | 44.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | KA | 5.4565 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Affinity constant | 10.0000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | KA | 5.4565 | 1 | 4 |
| Adenosine receptor A2b | Homo sapiens (human) | Affinity constant | 10.0000 | 1 | 1 |
| Carbonic anhydrase | Candida albicans SC5314 | KA | 19.8000 | 1 | 2 |
| Carbonic anhydrase | Methanosarcina thermophila | KA | 68.0000 | 1 | 2 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ka | 69.5000 | 1 | 2 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ka | 84.0000 | 2 | 4 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | KA | 44.5500 | 1 | 2 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ka | 30.5500 | 1 | 2 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Activity | 0.0300 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | KA | 0.4046 | 15 | 28 |
| Carbonic anhydrase 12 | Homo sapiens (human) | KA | 19.5700 | 2 | 4 |
| Carbonic anhydrase 13 | Homo sapiens (human) | KA | 0.5650 | 1 | 2 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | KA | 0.5750 | 1 | 2 |
| Carbonic anhydrase 14 | Homo sapiens (human) | KA | 0.5700 | 2 | 4 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | KA | 32.7500 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Activity | 10.0000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | KA | 16.0869 | 17 | 32 |
| Carbonic anhydrase 3 | Homo sapiens (human) | KA | 35.3667 | 3 | 6 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | KA | 39.0000 | 2 | 2 |
| Carbonic anhydrase 4 | Homo sapiens (human) | KA | 21.0125 | 4 | 8 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | KA | 5.5625 | 2 | 4 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | KA | 5.5975 | 2 | 4 |
| Carbonic anhydrase 6 | Homo sapiens (human) | KA | 15.1657 | 3 | 7 |
| Carbonic anhydrase 7 | Homo sapiens (human) | KA | 5.6925 | 2 | 4 |
| Carbonic anhydrase 9 | Homo sapiens (human) | KA | 12.2840 | 3 | 5 |
| Carbonic anhydrase-like protein, putative | Trypanosoma cruzi strain CL Brener | KA | 11.7000 | 1 | 2 |
| Collagenase 3 | Homo sapiens (human) | Kb | 1.2000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | Activity | 1.2500 | 1 | 1 |
| Estrogen receptor | Mus musculus (house mouse) | Kis | 19,400.0000 | 1 | 4 |
| Estrogen receptor beta | Mus musculus (house mouse) | Kis | 19,400.0000 | 1 | 4 |
| Glutamate 5-kinase | Escherichia coli K-12 | I0.5 | 2.5000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | KA | 5.9250 | 1 | 2 |
| Guanine deaminase | Homo sapiens (human) | Km | 11.2100 | 1 | 1 |
| Hypoxanthine-guanine phosphoribosyltransferase | Homo sapiens (human) | Km | 1.9000 | 2 | 2 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | INH | 1,000.0000 | 1 | 1 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | Km | 12.6000 | 2 | 2 |
| Monocarboxylate transporter 1 | Rattus norvegicus (Norway rat) | Km | 336.5250 | 2 | 2 |
| Monocarboxylate transporter 10 | Rattus norvegicus (Norway rat) | Km | 7,020.0000 | 1 | 1 |
| Monocarboxylate transporter 4 | Homo sapiens (human) | Km | 75,500.0000 | 1 | 2 |
| ORF73 | Human gammaherpesvirus 8 | AC50 | 350.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Emax | 51.0000 | 1 | 1 |
| Plasma kallikrein | Homo sapiens (human) | KA | 5.7100 | 1 | 2 |
| Polyphenol oxidase 2 | Agaricus bisporus | ID50 | 2,900.0000 | 2 | 2 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | pKi | 2,000.0000 | 1 | 1 |
| Purine nucleoside phosphorylase | Bos taurus (cattle) | Kieq | 4.0000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | ED50 | 50.0000 | 1 | 1 |
| S-methyl-5'-thioadenosine phosphorylase | Homo sapiens (human) | Km | 38.5333 | 2 | 3 |
| SLC16A10 protein | Homo sapiens (human) | Km | 740.5000 | 1 | 1 |
| Solute carrier family 22 member 7 | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Activity | 19,400.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Kis | 19,400.0000 | 1 | 1 |