Roles > protein kinase inhibitor
Page last updated: 2024-08-05 15:21:39

protein kinase inhibitor

An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.

ChEBI ID: 37699

Members (13)

MemberDefinitionClass
2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide2-({2-[(3-hydroxyphenyl)amino]pyrimidin-4-yl}amino)benzamide
3,3',4,5'-tetrahydroxystilbeneA stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.piceatannol
aminopurvalanol aaminopurvalanol
DMH1A pyrazolopyrimidine that is pyrazolo[1,5-a]pyrimidine bearing quinolin-4-yl and 4-isopropyloxyphenyl substituents at positions 3 and 6 respectively.DMH1
ekb 569pelitinib
erlotinibA quinazoline compound having a (3-ethynylphenyl)amino group at the 4-position and two 2-methoxyethoxy groups at the 6- and 7-positions.erlotinib
erlotinib hydrochlorideThe hydrochloride salt of erlotinib.erlotinib hydrochloride
gamma-mangostinA member of the class of xanthones that is 9H-xanthene substituted by hydroxy group at positions 1, 3, 6 and 7, an oxo group at position 9 and prenyl groups at positions 2 and 8. Isolated from the stems of Cratoxylum cochinchinense, it exhibits antitumour activity.gamma-mangostin
miltefosineA phospholipid that is the hexadecyl monoester of phosphocholine.miltefosine
nsc 65346A nucleoside analogue that is adenosine in which the nitrogen at position 7 is replaced by a carbamoyl-substituted carbon. It is a potent inhibitor of protein kinase C.sangivamycin
purvalanol bpurvalanol B
quercetinA pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. It is one of the most abundant flavonoids in edible vegetables, fruit and wine.quercetin
xmd 8-92A dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one carrying at C-2 on the pyrimidine ring a [2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino substituent. It is an inhibitor of the BMK1 kinase pathway.XMD8-92

Research

Studies (18,356)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990606 (3.30)18.7374
1990's1,016 (5.53)18.2507
2000's4,132 (22.51)29.6817
2010's9,165 (49.93)24.3611
2020's3,437 (18.72)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials1,115 (5.84%)5.53%
Reviews1,400 (7.33%)6.00%
Case Studies700 (3.66%)4.05%
Observational31 (0.16%)0.25%
Other15,862 (83.01%)84.16%

Protein Targets (890)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency20.401516
15-lipoxygenase, partialHomo sapiens (human)Potency0.794311
67.9K proteinVaccinia virusPotency25.400524
acid sphingomyelinaseHomo sapiens (human)Potency25.118911
activating transcription factor 6Homo sapiens (human)Potency3.116411
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency29.8141113
apical membrane antigen 1, AMA1Plasmodium falciparum 3D7Potency7.079511
AR proteinHomo sapiens (human)Potency18.1172712
aryl hydrocarbon receptorHomo sapiens (human)Potency33.051426
arylsulfatase AHomo sapiens (human)Potency28.871012
ATAD5 protein, partialHomo sapiens (human)Potency8.633545
Ataxin-2Homo sapiens (human)Potency3.162311
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency6.343723
atrial natriuretic peptide receptor 1 precursorHomo sapiens (human)Potency21.331311
atrial natriuretic peptide receptor 2 precursorHomo sapiens (human)Potency16.481611
Bloom syndrome protein isoform 1Homo sapiens (human)Potency28.378426
BRCA1Homo sapiens (human)Potency17.782811
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency50.118711
Cellular tumor antigen p53Homo sapiens (human)Potency40.514125
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency11.711623
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency17.458017
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency1.618227
Chain A, CruzipainTrypanosoma cruziPotency19.957425
Chain A, Ferritin light chainEquus caballus (horse)Potency32.464822
Chain A, HADH2 proteinHomo sapiens (human)Potency1.895825
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency44.668411
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency8.0998212
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency15.811412
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency26.560014
Chain B, HADH2 proteinHomo sapiens (human)Potency1.895825
chromobox protein homolog 1Homo sapiens (human)Potency35.061923
cytochrome P450 2C19 precursorHomo sapiens (human)Potency15.848912
cytochrome P450 2C9 precursorHomo sapiens (human)Potency13.948014
cytochrome P450 2C9, partialHomo sapiens (human)Potency11.198313
cytochrome P450 2D6Homo sapiens (human)Potency28.912913
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency35.716812
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency3.312924
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency8.530615
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency23.526313
D(1A) dopamine receptorHomo sapiens (human)Potency3.052123
D(1A) dopamine receptorSus scrofa (pig)Potency23.280911
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency31.622811
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)Potency35.481311
DNA polymerase betaHomo sapiens (human)Potency4.071412
DNA polymerase eta isoform 1Homo sapiens (human)Potency9.288612
DNA polymerase III, partialBacillus subtilisPotency10.621311
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency46.242314
DNA polymerase kappa isoform 1Homo sapiens (human)Potency11.8401112
dual specificity protein kinase CLK4Homo sapiens (human)Potency20.666511
dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform 1Homo sapiens (human)Potency18.419111
epidermal growth factor receptor isoform a precursorHomo sapiens (human)Potency0.297733
estrogen nuclear receptor alphaHomo sapiens (human)Potency17.9773613
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency23.566123
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency20.91991025
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency7.971219
EWS/FLI fusion proteinHomo sapiens (human)Potency12.8046416
farnesoid X nuclear receptorHomo sapiens (human)Potency21.589622
flap endonuclease 1Homo sapiens (human)Potency9.250725
Fumarate hydrataseHomo sapiens (human)Potency14.125411
GVesicular stomatitis virusPotency11.198313
GABA theta subunitRattus norvegicus (Norway rat)Potency3.312912
galactokinaseHomo sapiens (human)Potency42.128511
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency3.312912
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency3.312912
gemininHomo sapiens (human)Potency13.940734
GLI family zinc finger 3Homo sapiens (human)Potency19.615127
GLS proteinHomo sapiens (human)Potency12.641123
glucocerebrosidaseHomo sapiens (human)Potency22.333515
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency32.245233
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency16.784023
heat shock protein beta-1Homo sapiens (human)Potency33.488911
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency12.4536220
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency34.913413
histone deacetylase 9 isoform 3Homo sapiens (human)Potency24.516324
Histone H2A.xCricetulus griseus (Chinese hamster)Potency45.650024
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency22.387211
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency11.198313
hypothetical protein, conservedTrypanosoma bruceiPotency9.379944
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency10.000022
IDH1Homo sapiens (human)Potency23.109311
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency11.198316
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency11.269813
Integrin alpha-IIbHomo sapiens (human)Potency17.067412
Integrin beta-3Homo sapiens (human)Potency17.067412
Interferon betaHomo sapiens (human)Potency10.0641316
lamin isoform A-delta10Homo sapiens (human)Potency8.371025
lethal factor (plasmid)Bacillus anthracis str. A2012Potency25.118911
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency31.622811
LuciferasePhotinus pyralis (common eastern firefly)Potency30.382434
luciferasePhoturis pensylvanica (Pennsylania firefly)Potency12.589311
M-phase phosphoprotein 8Homo sapiens (human)Potency33.604613
Microtubule-associated protein tauHomo sapiens (human)Potency8.4669214
mitogen-activated protein kinase 1Homo sapiens (human)Potency34.352123
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency11.557422
muscleblind-like protein 1 isoform 1Homo sapiens (human)Potency22.983312
neuropeptide S receptor isoform AHomo sapiens (human)Potency0.158511
NFKB1 protein, partialHomo sapiens (human)Potency5.623422
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency6.513111
Nrf2Homo sapiens (human)Potency26.619412
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency2.127022
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency32.642711
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency8.912511
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency28.765539
P53Homo sapiens (human)Potency10.000011
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency5.623411
ParkinHomo sapiens (human)Potency7.548624
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency2.685511
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency38.943012
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency46.496812
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency44.020611
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency17.963323
phosphopantetheinyl transferaseBacillus subtilisPotency53.714517
plasminogen precursorMus musculus (house mouse)Potency7.943311
polyproteinZika virusPotency14.125411
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency2.196313
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency10.212114
PPM1D proteinHomo sapiens (human)Potency9.634818
pregnane X nuclear receptorHomo sapiens (human)Potency35.439424
progesterone receptorHomo sapiens (human)Potency14.576012
RAF proto-oncogene serine/threonine-protein kinase isoform bHomo sapiens (human)Potency19.952611
Rap guanine nucleotide exchange factor 4Homo sapiens (human)Potency50.118711
RAR-related orphan receptor gammaMus musculus (house mouse)Potency35.335026
ras-related protein Rab-9AHomo sapiens (human)Potency58.047911
regulator of G-protein signaling 4Homo sapiens (human)Potency8.507114
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency28.080636
retinoid X nuclear receptor alphaHomo sapiens (human)Potency11.255726
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)Potency22.355433
signal transducer and activator of transcription 6, interleukin-4 inducedHomo sapiens (human)Potency2.511922
SMAD family member 2Homo sapiens (human)Potency12.330223
SMAD family member 3Homo sapiens (human)Potency12.330223
Smad3Homo sapiens (human)Potency35.481311
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency17.039012
survival motor neuron protein isoform dHomo sapiens (human)Potency27.018014
TDP1 proteinHomo sapiens (human)Potency13.7034217
thioredoxin glutathione reductaseSchistosoma mansoniPotency22.387211
thioredoxin reductaseRattus norvegicus (Norway rat)Potency14.692334
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency45.655125
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency55.193923
thyroid stimulating hormone receptorHomo sapiens (human)Potency30.207349
tyrosine-protein kinase YesHomo sapiens (human)Potency5.467313
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency25.057822
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency7.943311
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency7.943311
USP1 protein, partialHomo sapiens (human)Potency56.234112
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency32.493223
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency11.882311

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
1-deoxy-D-xylulose 5-phosphate reductoisomeraseEscherichia coli K-12IC501.900011
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)IC501.540022
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)IC505.400011
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)IC504.000011
5'-AMP-activated protein kinase subunit beta-1Homo sapiens (human)IC500.107911
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)IC500.107911
5'-nucleotidaseRattus norvegicus (Norway rat)Ki0.045311
7,8-dihydro-8-oxoguanine triphosphataseHomo sapiens (human)IC502.000011
72 kDa type IV collagenaseHomo sapiens (human)IC506.680011
AcetylcholinesteraseHomo sapiens (human)Ki38.300011
Activin receptor type-1Homo sapiens (human)IC500.105333
Activin receptor type-1BHomo sapiens (human)IC509.622011
Adenosine kinaseHomo sapiens (human)IC501,066,402.735044
Adenosine kinaseMycobacterium tuberculosis H37RvIC5016.500011
Adenosine receptor A1Rattus norvegicus (Norway rat)IC501,068,980.003222
Adenosine receptor A1Rattus norvegicus (Norway rat)Ki8.900033
Adenosine receptor A2aRattus norvegicus (Norway rat)IC502,137,960.000011
Adenosine receptor A2aRattus norvegicus (Norway rat)Ki5.125022
Adenosine receptor A2bRattus norvegicus (Norway rat)IC502,137,960.000011
Adenosine receptor A3Rattus norvegicus (Norway rat)IC502,137,960.000011
Adenosine receptor A3Homo sapiens (human)Ki30.000011
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1Homo sapiens (human)IC5068.950012
Aldo-keto reductase family 1 member A1Rattus norvegicus (Norway rat)IC502.320011
Aldo-keto reductase family 1 member A1Sus scrofa (pig)IC5038.400011
Aldo-keto reductase family 1 member B1Bos taurus (cattle)IC5017.754055
Aldo-keto reductase family 1 member B1Homo sapiens (human)IC502.214166
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)IC506.641756
Aldo-keto reductase family 1 member B1Sus scrofa (pig)IC5050.100011
Aldo-keto reductase family 1 member C21Mus musculus (house mouse)IC506.900011
Aldo-keto reductase family 1 member C21Mus musculus (house mouse)Ki11.000011
ALK tyrosine kinase receptorHomo sapiens (human)IC503.320011
Alpha-1A adrenergic receptor Sus scrofa (pig)IC500.300011
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)IC5039.900012
Alpha-amylase 1A Homo sapiens (human)IC5021.400022
Alpha-synucleinHomo sapiens (human)IC5020.000011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC502.620022
Amine oxidase [flavin-containing] A Bos taurus (cattle)IC500.010011
Amine oxidase [flavin-containing] BBos taurus (cattle)IC5020.000011
Amine oxidase [flavin-containing] BHomo sapiens (human)IC5064.330022
Amyloid-beta precursor proteinHomo sapiens (human)IC5040.785044
Anthrax toxin receptor 2Homo sapiens (human)IC50300.000011
Arginase Leishmania amazonensisIC504.000011
Arginase-1Bos taurus (cattle)IC5047.000011
Arginase-1Homo sapiens (human)IC50622.500022
Arginase-1Bos taurus (cattle)Ki136.000033
AromataseHomo sapiens (human)IC505.970544
ATP-binding cassette sub-family C member 3Homo sapiens (human)IC50133.000011
ATP-dependent translocase ABCB1Homo sapiens (human)IC5039.250022
Aurora kinase BHomo sapiens (human)IC5034.956733
B2 bradykinin receptorCavia porcellus (domestic guinea pig)IC504.000022
Beta-adrenergic receptor kinase 1Homo sapiens (human)Ki67.000011
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)IC501.500011
Beta-lactamaseEnterobacter cloacaeIC50269.666733
Beta-lactamaseEscherichia coli K-12IC5058.000044
Beta-secretase 1Homo sapiens (human)IC507.640033
Beta-secretase 1Homo sapiens (human)Ki14.000011
Bifunctional epoxide hydrolase 2Homo sapiens (human)IC5020.270022
Bile salt export pumpHomo sapiens (human)IC5092.666733
Bone morphogenetic protein receptor type-1AHomo sapiens (human)IC500.005011
Bone morphogenetic protein receptor type-1BHomo sapiens (human)IC500.047611
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)IC5016.157544
C-C chemokine receptor type 4Homo sapiens (human)IC5047.240936
C-X-C chemokine receptor type 1Homo sapiens (human)IC5035.378024
Calcium dependent protein kinaseTriticum aestivum (bread wheat)IC5019.000011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1BRattus norvegicus (Norway rat)IC50275.000011
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1CRattus norvegicus (Norway rat)IC50275.000011
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)IC503.000011
Calmodulin-1Homo sapiens (human)IC5012.970011
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)IC503.800011
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)IC503.800011
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)IC503.800011
Canalicular multispecific organic anion transporter 1Homo sapiens (human)IC5071.500022
Carbonic anhydrase 1Homo sapiens (human)Ki29.913848
Carbonic anhydrase 12Homo sapiens (human)Ki9.390011
Carbonic anhydrase 13Mus musculus (house mouse)Ki9.030011
Carbonic anhydrase 14Homo sapiens (human)Ki5.410011
Carbonic anhydrase 2Homo sapiens (human)Ki29.896248
Carbonic anhydrase 3Bos taurus (cattle)Ki6.526025
Carbonic anhydrase 3Homo sapiens (human)Ki8.100011
Carbonic anhydrase 4Homo sapiens (human)Ki6.753336
Carbonic anhydrase 5A, mitochondrialHomo sapiens (human)Ki6.810011
Carbonic anhydrase 5B, mitochondrialHomo sapiens (human)Ki11.900011
Carbonic anhydrase 6Homo sapiens (human)Ki4.950022
Carbonic anhydrase 7Homo sapiens (human)Ki4.840011
Carbonic anhydrase 9Homo sapiens (human)Ki7.000011
Casein kinase II subunit alphaHomo sapiens (human)IC502.711477
Casein kinase II subunit alphaHomo sapiens (human)Ki1.180044
Casein kinase II subunit alpha 3Homo sapiens (human)IC505.275022
Casein kinase II subunit alpha 3Homo sapiens (human)Ki1.180011
Casein kinase II subunit alpha'Homo sapiens (human)IC502.711477
Casein kinase II subunit alpha'Homo sapiens (human)Ki1.180011
Casein kinase II subunit betaHomo sapiens (human)IC502.711477
Casein kinase II subunit betaHomo sapiens (human)Ki1.180011
Cationic trypsinBos taurus (cattle)IC5024.420025
Cdc2Patiria pectiniferaIC500.150022
cGMP-dependent 3',5'-cyclic phosphodiesteraseRattus norvegicus (Norway rat)IC5081.300011
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydrataseHelicobacter pyloriKi12.700013
Chain A, APH(2')-IdEnterococcus casseliflavusKi25.100011
Chain A, Mitogen-activated protein kinase 8Homo sapiens (human)IC500.009011
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydrataseHelicobacter pyloriKi12.700013
Chymotrypsin-CHomo sapiens (human)IC50100.000011
Chymotrypsin-like elastase family member 1Sus scrofa (pig)IC5028.750014
Chymotrypsinogen ABos taurus (cattle)IC50292.500022
Chymotrypsinogen BHomo sapiens (human)IC50100.000011
Collagenase 3Homo sapiens (human)IC508.460011
Corticosteroid 11-beta-dehydrogenase isozyme 1 Rattus norvegicus (Norway rat)IC500.030011
Cyclin homologHerpesvirus saimiri (strain 11)IC5031.275014
Cyclin-A1Homo sapiens (human)IC500.006011
Cyclin-A2Homo sapiens (human)IC500.006022
Cyclin-dependent kinase 1Homo sapiens (human)IC50103.2305911
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)IC5025.021225
Cyclin-dependent kinase 1Saccharomyces cerevisiae S288CIC501.200011
Cyclin-dependent kinase 2Homo sapiens (human)IC505.484588
Cyclin-dependent kinase 4Homo sapiens (human)IC5027.000033
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)IC5021.158947
Cyclin-dependent kinase 6Homo sapiens (human)IC5030.020025
Cyclin-dependent-like kinase 5 Homo sapiens (human)IC5021.158947
Cyclin-G-associated kinaseHomo sapiens (human)IC500.474022
Cytochrome P450 11B1, mitochondrialRattus norvegicus (Norway rat)IC5050.000011
Cytochrome P450 1A1Homo sapiens (human)IC508.436455
Cytochrome P450 1A1Homo sapiens (human)Ki0.660011
Cytochrome P450 1A2Homo sapiens (human)IC5036.024244
Cytochrome P450 1B1Homo sapiens (human)IC501.110855
Cytochrome P450 1B1Homo sapiens (human)Ki0.023022
Cytochrome P450 2C19Homo sapiens (human)IC5050.043522
Cytochrome P450 2C8Homo sapiens (human)IC5013.500022
Cytochrome P450 2C9 Homo sapiens (human)IC50100.000011
Cytochrome P450 2C9 Homo sapiens (human)Ki27.000011
Cytochrome P450 2D6Homo sapiens (human)IC5046.666733
Cytochrome P450 3A4Homo sapiens (human)IC5029.403255
Cytochrome P450 3A4Homo sapiens (human)Ki6.300013
Cytosol aminopeptidaseSus scrofa (pig)IC5034.300011
D(1A) dopamine receptorSus scrofa (pig)IC500.300011
D(4) dopamine receptorHomo sapiens (human)Ki7.846011
Death-associated protein kinase 1Homo sapiens (human)IC508.900011
Dipeptidyl peptidase 3Homo sapiens (human)IC5074.100011
Dipeptidyl peptidase 4Homo sapiens (human)IC5066.460022
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)IC5038.000011
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)IC508.400022
Dual specificity protein kinase CLK2Homo sapiens (human)IC500.107911
ELAV-like protein 1Homo sapiens (human)IC501.400011
ELAV-like protein 3Homo sapiens (human)IC501.800011
Enoyl-[acyl-carrier-protein] reductase [NADH] FabIEscherichia coli K-12IC5020.000011
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)IC501.833333
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)Ki0.528333
Epidermal growth factor receptorHomo sapiens (human)IC504.6468166173
Epidermal growth factor receptorHomo sapiens (human)Ki0.04751313
epidermal growth factor receptor isoform a precursorHomo sapiens (human)IC500.001011
Epoxide hydrolase 1 Homo sapiens (human)IC507.000011
Fatty acid synthaseHomo sapiens (human)IC501.240011
Fatty-acid amide hydrolase 1Rattus norvegicus (Norway rat)IC500.009522
Focal adhesion kinase 1Homo sapiens (human)IC504.300022
G-protein coupled receptor 35Homo sapiens (human)IC5015.400011
G1/S-specific cyclin-D1Homo sapiens (human)IC5027.000033
G1/S-specific cyclin-E1Homo sapiens (human)IC500.009011
G1/S-specific cyclin-E2Homo sapiens (human)IC500.009011
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)IC5025.021225
G2/mitotic-specific cyclin-B1Homo sapiens (human)IC5014.385868
G2/mitotic-specific cyclin-B2Homo sapiens (human)IC5015.016035
G2/mitotic-specific cyclin-B3Homo sapiens (human)IC5015.016035
glucose-6-phosphate dehydrogenaseLeuconostoc mesenteroidesIC5025.000011
Glutathione reductaseSaccharomyces cerevisiae S288CIC5048.800011
Glutathione reductase, mitochondrialHomo sapiens (human)IC50218.000011
Glyceraldehyde-3-phosphate dehydrogenase, glycosomalTrypanosoma cruziIC50142.000011
Glycogen phosphorylase, liver formHomo sapiens (human)IC504.800011
Glycogen synthase kinase-3 alphaHomo sapiens (human)IC502.100011
Glycogen synthase kinase-3 betaHomo sapiens (human)IC506.050022
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)IC5031.275014
Heat shock factor protein 1Homo sapiens (human)IC5050.000011
Hepatocyte growth factor receptorHomo sapiens (human)IC506.540022
hexokinaseTrypanosoma brucei brucei TREU927IC5022.378011
Histone-lysine N-methyltransferase, H3 lysine-79 specificHomo sapiens (human)IC5026.000011
Hypoxia-inducible factor 1-alpha inhibitorHomo sapiens (human)IC5010.200011
Inositol hexakisphosphate kinase 2Homo sapiens (human)IC500.700011
Inositol polyphosphate multikinaseHomo sapiens (human)IC502.300011
Insulin receptorHomo sapiens (human)IC5014.900033
Insulin-like growth factor 1 receptorHomo sapiens (human)IC5017.575044
Integrase Human immunodeficiency virus 1IC5013.160055
Interstitial collagenaseHomo sapiens (human)IC501.490011
Isocitrate dehydrogenase [NADP] cytoplasmicHomo sapiens (human)Ki3.170011
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)IC501.000011
LactoperoxidaseBos taurus (cattle)IC506.100011
Lactoylglutathione lyaseHomo sapiens (human)IC501.980022
Lactoylglutathione lyaseHomo sapiens (human)Ki15.135611
large T antigenBetapolyomavirus macacaeIC5016.350011
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)IC500.046011
Lysine-specific histone demethylase 1AHomo sapiens (human)IC5018.530022
Lysosomal alpha-glucosidaseHomo sapiens (human)IC504.750022
Lysosomal alpha-glucosidaseHomo sapiens (human)Ki1.400011
M-phase inducer phosphatase 1Homo sapiens (human)IC5025.000011
Macrophage metalloelastaseHomo sapiens (human)IC5010.230011
Malate dehydrogenaseThermus thermophilusIC506.000011
Maltase-glucoamylase, intestinalHomo sapiens (human)IC506.766733
Maltase-glucoamylase, intestinalHomo sapiens (human)Ki1.400011
MAP kinase-activated protein kinase 2Homo sapiens (human)IC5050.000011
Matrix metalloproteinase-9Homo sapiens (human)IC500.891922
Mitogen-activated protein kinase 1Homo sapiens (human)IC5025.000011
Mitogen-activated protein kinase 10Homo sapiens (human)IC505.253323
Mitogen-activated protein kinase 11Homo sapiens (human)IC5050.000011
Mitogen-activated protein kinase 12Homo sapiens (human)IC5050.000011
Mitogen-activated protein kinase 13Homo sapiens (human)IC5050.000011
Mitogen-activated protein kinase 14Homo sapiens (human)IC5018.586723
Mitogen-activated protein kinase 3 Homo sapiens (human)IC503.316522
Mitogen-activated protein kinase 7Homo sapiens (human)IC500.560044
Mitogen-activated protein kinase 8Homo sapiens (human)IC501.902866
Mitogen-activated protein kinase 9Homo sapiens (human)IC5010.000011
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)IC5050.000011
Monocarboxylate transporter 1Rattus norvegicus (Norway rat)IC5014.000011
Monocarboxylate transporter 2Rattus norvegicus (Norway rat)IC505.000011
Multidrug resistance-associated protein 1 Homo sapiens (human)Ki5.250022
Multidrug resistance-associated protein 4Homo sapiens (human)IC5020.800011
MyeloperoxidaseHomo sapiens (human)IC501.697544
Myosin light chain kinase, smooth muscleHomo sapiens (human)IC5012.000022
NADPH oxidase 4Homo sapiens (human)IC500.680011
NeuraminidaseInfluenza A virus (A/Puerto Rico/8/1934(H1N1))IC507.750011
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))IC5053.925044
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))Ki3.800011
Neutrophil elastaseHomo sapiens (human)IC5018.339022
Neutrophil elastaseHomo sapiens (human)Ki11.900011
Nitric oxide synthase, inducibleMus musculus (house mouse)IC5016.400011
NUAK family SNF1-like kinase 1Homo sapiens (human)IC505.090011
Oligo-1,6-glucosidase IMA1Saccharomyces cerevisiae S288CIC50530.000011
Pancreatic triacylglycerol lipaseSus scrofa (pig)IC5070.000011
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)IC503.800011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)IC508.795022
Phosphodiesterase Rattus norvegicus (Norway rat)IC50275.000011
Phosphoglycerate mutase 1Homo sapiens (human)IC501.900011
Phospholipase A2Homo sapiens (human)IC502.000011
Platelet-activating factor receptorCavia porcellus (domestic guinea pig)IC50200.000011
Platelet-derived growth factor receptor alphaHomo sapiens (human)IC508.120011
Platelet-derived growth factor receptor betaHomo sapiens (human)IC5035.113399
Polyphenol oxidase 2Agaricus bisporusIC50135.500022
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)IC505.161477
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)IC501.950066
Polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)IC500.440011
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)IC502.200011
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)IC5018.715022
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)IC50100.000011
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC5062.500022
Probable maltase-glucoamylase 2Homo sapiens (human)IC504.750022
Probable maltase-glucoamylase 2Homo sapiens (human)Ki1.400011
Prolyl endopeptidaseHomo sapiens (human)IC5013.000011
Prostaglandin G/H synthase 1Homo sapiens (human)IC500.800011
Prostaglandin G/H synthase 1Ovis aries (sheep)IC5010.000011
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)IC5050.000022
Prostaglandin G/H synthase 2Homo sapiens (human)IC5013.533333
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)IC5050.000022
Proteasome subunit beta type-5Homo sapiens (human)IC502.750022
Protein E6Human papillomavirus 16IC5020.000011
Protein kinase C alpha typeHomo sapiens (human)IC50100.000011
Protein kinase C beta typeHomo sapiens (human)IC50100.000022
Protein kinase C delta typeHomo sapiens (human)IC50100.000011
Protein kinase C epsilon typeHomo sapiens (human)IC50100.000011
Protein kinase C eta typeHomo sapiens (human)IC50100.000011
Protein kinase C gamma typeHomo sapiens (human)IC50100.000011
Protein kinase C zeta typeHomo sapiens (human)IC50100.000011
ProthrombinHomo sapiens (human)IC5015.750022
Prothrombin Bos taurus (cattle)IC5028.750014
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)IC5078.100011
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)IC507.995034
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)IC507.560022
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)IC509.996733
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)IC501.70544852
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)Ki0.031833
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)IC500.258688
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)Ki0.031833
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)IC500.69251012
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)Ki0.031833
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)IC500.590011
Replicase polyprotein 1abBetacoronavirus England 1IC5010.000011
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC5023.800011
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusIC5026.425044
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2Ki7.400011
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusKi7.400011
Rhodopsin kinase GRK1Homo sapiens (human)Ki0.180011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)IC509.000011
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)Ki106.700011
Serine/threonine-protein kinase B-rafHomo sapiens (human)IC503.824522
Serine/threonine-protein kinase B-raf Mus musculus (house mouse)IC500.050022
Serine/threonine-protein kinase Chk1Homo sapiens (human)IC500.820011
Serine/threonine-protein kinase DCLK1Homo sapiens (human)IC500.716011
Serine/threonine-protein kinase N1Homo sapiens (human)IC505.800011
Serine/threonine-protein kinase Nek2Homo sapiens (human)IC503.195522
Serine/threonine-protein kinase Nek6Homo sapiens (human)IC504.230011
Serine/threonine-protein kinase PAK 4Homo sapiens (human)IC505.500011
Serine/threonine-protein kinase pim-1Homo sapiens (human)IC500.768655
Serine/threonine-protein kinase PLK1Homo sapiens (human)IC5023.493333
Serine/threonine-protein kinase receptor R3Homo sapiens (human)IC500.027011
Serine/threonine-protein kinase TBK1Homo sapiens (human)IC502.200011
Short transient receptor potential channel 5Homo sapiens (human)IC506.500011
SialidaseClostridium perfringensIC508.633356
SialidaseClostridium perfringensKi4.105022
Sialidase-2Homo sapiens (human)IC50160.000011
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)IC5050.000011
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)IC5050.000011
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)IC5050.000011
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)IC5050.000011
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)IC5010.184522
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)IC501.000011
Solute carrier family 2, facilitated glucose transporter member 2Homo sapiens (human)IC5012.000022
Solute carrier family 2, facilitated glucose transporter member 4 Rattus norvegicus (Norway rat)Ki16.000011
Solute carrier family 22 member 1 Homo sapiens (human)IC5016.200011
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)IC5021.000011
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)Ki21.000011
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)IC5044.000011
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)Ki41.000011
Solute carrier organic anion transporter family member 2B1 Homo sapiens (human)IC500.550011
Solute carrier organic anion transporter family member 2B1 Homo sapiens (human)Ki0.530011
Sorbitol dehydrogenaseHomo sapiens (human)IC50106.300022
Stromelysin-1Homo sapiens (human)IC505.570011
Substance-K receptorCavia porcellus (domestic guinea pig)IC5058.400011
Substance-P receptorCavia porcellus (domestic guinea pig)IC5058.400011
Sucrase-isomaltase, intestinalHomo sapiens (human)IC504.750022
Sucrase-isomaltase, intestinalHomo sapiens (human)Ki1.400011
Synaptic vesicular amine transporterRattus norvegicus (Norway rat)IC500.001011
TGF-beta receptor type-1Homo sapiens (human)IC500.107911
TransthyretinHomo sapiens (human)IC5010.000011
Trypsin-1Homo sapiens (human)IC5015.400011
Trypsin-2Homo sapiens (human)IC5015.400011
Trypsin-3Homo sapiens (human)IC5015.400011
TyrosinaseHomo sapiens (human)IC5044.380011
Tyrosine-protein kinase JAK2Homo sapiens (human)IC5012.000022
Tyrosine-protein kinase LckHomo sapiens (human)IC5029.834356
Tyrosine-protein kinase receptor UFOHomo sapiens (human)IC500.960011
Tyrosine-protein kinase SYKHomo sapiens (human)IC5022.666733
Tyrosine-protein kinase YesHomo sapiens (human)Ki0.472011
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)IC5016.466733
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)Ki2.700011
Urease subunit alphaHelicobacter pylori 26695IC5011.133333
Urease subunit alphaHelicobacter pylori 26695Ki9.340011
Urease subunit betaHelicobacter pylori 26695IC5011.133333
Urease subunit betaHelicobacter pylori 26695Ki9.340011
Urokinase-type plasminogen activatorHomo sapiens (human)IC5025.420025
Vascular endothelial growth factor receptor 1 Homo sapiens (human)IC500.250011
Vascular endothelial growth factor receptor 2Homo sapiens (human)IC5038.50322020
Vascular endothelial growth factor receptor 3Homo sapiens (human)IC500.250011
Vasopressin V2 receptorHomo sapiens (human)IC5020.328236
Xanthine dehydrogenase/oxidaseBos taurus (cattle)IC5031.900011
Xanthine dehydrogenase/oxidaseHomo sapiens (human)IC503.040033
Xanthine dehydrogenase/oxidaseBos taurus (cattle)Ki1.200011
Xanthine dehydrogenase/oxidaseHomo sapiens (human)Ki0.280011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
26S proteasome regulatory subunit 6BHomo sapiens (human)Kd30.000012
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)Kd10.000023
5-hydroxytryptamine receptor 1AHomo sapiens (human)EC50100.000011
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)Kd18.000035
5'-AMP-activated protein kinase catalytic subunit alpha-2Homo sapiens (human)Kd10.000023
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)Kd30.000012
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)Kd30.000012
AarF domain-containing protein kinase 1Homo sapiens (human)Kd30.000012
Actin-related protein 2Homo sapiens (human)Kd30.000012
Actin-related protein 3Homo sapiens (human)Kd30.000012
Activated CDC42 kinase 1Homo sapiens (human)Kd12.310057
Activin receptor type-1Homo sapiens (human)Kd18.000035
Activin receptor type-1BHomo sapiens (human)Kd18.000035
Activin receptor type-2AHomo sapiens (human)Kd10.000023
Activin receptor type-2BHomo sapiens (human)Kd18.000035
Acyl-CoA dehydrogenase family member 10Homo sapiens (human)Kd30.000012
Acyl-CoA dehydrogenase family member 11Homo sapiens (human)Kd17.073512
Adenine phosphoribosyltransferaseHomo sapiens (human)Kd30.000012
Adenosine kinaseHomo sapiens (human)Kd30.000012
Adenylate kinase 2, mitochondrialHomo sapiens (human)Kd30.000012
ADP/ATP translocase 2Homo sapiens (human)Kd30.000012
ADP/ATP translocase 3Homo sapiens (human)Kd30.000012
ALK tyrosine kinase receptorHomo sapiens (human)Kd3.166723
Angiopoietin-1 receptorHomo sapiens (human)Kd8.225034
Angiotensin-converting enzyme 2 Homo sapiens (human)EC5083.400011
Ankyrin repeat and protein kinase domain-containing protein 1Homo sapiens (human)Kd10.000023
AP2-associated protein kinase 1Homo sapiens (human)Kd9.225058
ATP-dependent 6-phosphofructokinase, platelet typeHomo sapiens (human)Kd30.000012
ATP-dependent RNA helicase DDX1Homo sapiens (human)Kd30.000012
ATP-dependent RNA helicase DDX3XHomo sapiens (human)Kd30.000012
ATP-dependent RNA helicase DDX42Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DHX30Homo sapiens (human)Kd30.000012
ATP-dependent translocase ABCB1Homo sapiens (human)EC504.930011
ATP-dependent translocase ABCB1Homo sapiens (human)Kd7.079511
Atypical kinase COQ8A, mitochondrialHomo sapiens (human)Kd14.760035
Atypical kinase COQ8B, mitochondrialHomo sapiens (human)Kd3.700023
Aurora kinase AHomo sapiens (human)Kd13.535058
Aurora kinase BHomo sapiens (human)Kd12.146746
Aurora kinase CHomo sapiens (human)Kd2.820034
BDNF/NT-3 growth factors receptorHomo sapiens (human)Kd10.000023
Beta-adrenergic receptor kinase 1Homo sapiens (human)Kd30.000012
BMP-2-inducible protein kinaseHomo sapiens (human)Kd2.282747
Bone morphogenetic protein receptor type-1AHomo sapiens (human)Kd18.000035
Bone morphogenetic protein receptor type-1BHomo sapiens (human)Kd23.333323
Bone morphogenetic protein receptor type-2Homo sapiens (human)Kd18.000035
Breakpoint cluster region proteinHomo sapiens (human)Kd1.512512
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)EC500.189044
Bromodomain testis-specific proteinHomo sapiens (human)Kd2.791733
Bromodomain-containing protein 4Homo sapiens (human)Kd0.835044
Calcium-dependent protein kinase 1Plasmodium falciparum 3D7Kd10.000011
Calcium/calmodulin-dependent protein kinase kinase 1Homo sapiens (human)Kd8.366723
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)Kd9.348346
Calcium/calmodulin-dependent protein kinase type 1Homo sapiens (human)Kd10.000023
Calcium/calmodulin-dependent protein kinase type 1DHomo sapiens (human)Kd7.425034
Calcium/calmodulin-dependent protein kinase type 1GHomo sapiens (human)Kd10.000023
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)Kd10.000023
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)Kd10.000023
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)Kd17.280035
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)Kd18.000035
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)Kd18.000035
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Kd18.000035
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Kd18.000035
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)Kd10.000023
cAMP-dependent protein kinase type II-alpha regulatory subunitHomo sapiens (human)Kd30.000012
Casein kinase I isoform alphaHomo sapiens (human)Kd23.333323
Casein kinase I isoform alpha-likeHomo sapiens (human)Kd7.000023
Casein kinase I isoform deltaHomo sapiens (human)Kd8.395835
Casein kinase I isoform epsilonHomo sapiens (human)Kd7.030246
Casein kinase I isoform gamma-1Homo sapiens (human)Kd18.000035
Casein kinase I isoform gamma-2Homo sapiens (human)Kd18.000035
Casein kinase I isoform gamma-3Homo sapiens (human)Kd18.000035
Casein kinase II subunit alphaHomo sapiens (human)Kd10.000023
Casein kinase II subunit alpha'Homo sapiens (human)Kd18.000035
Cell division control protein 2 homologPlasmodium falciparum 3D7Kd10.000011
Cell division cycle 7-related protein kinaseHomo sapiens (human)Kd30.000012
cGMP-dependent protein kinase 1 Homo sapiens (human)Kd18.000035
cGMP-dependent protein kinase 2Homo sapiens (human)Kd10.000023
Chain A, G protein-coupled receptor kinase 6Homo sapiens (human)Kd1.000011
Choline-phosphate cytidylyltransferase AHomo sapiens (human)Kd30.000011
Chromodomain-helicase-DNA-binding protein 4Homo sapiens (human)Kd30.000012
Citron Rho-interacting kinaseHomo sapiens (human)Kd12.334035
Cyclin-dependent kinase 1Homo sapiens (human)Kd30.000012
Cyclin-dependent kinase 10Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 11AHomo sapiens (human)Kd10.000023
Cyclin-dependent kinase 11BHomo sapiens (human)Kd10.000023
Cyclin-dependent kinase 12Homo sapiens (human)Kd30.000012
Cyclin-dependent kinase 13Homo sapiens (human)Kd23.333323
Cyclin-dependent kinase 14Homo sapiens (human)Kd10.000023
Cyclin-dependent kinase 15Homo sapiens (human)Kd10.000011
Cyclin-dependent kinase 16Homo sapiens (human)Kd16.666746
Cyclin-dependent kinase 17Homo sapiens (human)Kd18.000035
Cyclin-dependent kinase 18Homo sapiens (human)Kd10.000023
Cyclin-dependent kinase 19Homo sapiens (human)Kd10.000023
Cyclin-dependent kinase 2Homo sapiens (human)Kd18.000035
Cyclin-dependent kinase 3Homo sapiens (human)Kd18.000035
Cyclin-dependent kinase 4Homo sapiens (human)Kd20.000034
Cyclin-dependent kinase 6Homo sapiens (human)Kd30.000012
Cyclin-dependent kinase 7Homo sapiens (human)Kd18.000035
Cyclin-dependent kinase 8Homo sapiens (human)Kd10.000023
Cyclin-dependent kinase 9Homo sapiens (human)Kd18.000035
Cyclin-dependent kinase-like 1Homo sapiens (human)Kd10.000011
Cyclin-dependent kinase-like 2Homo sapiens (human)Kd10.000011
Cyclin-dependent kinase-like 3Homo sapiens (human)Kd10.000011
Cyclin-dependent kinase-like 5Homo sapiens (human)Kd20.000022
Cyclin-dependent-like kinase 5 Homo sapiens (human)Kd18.000035
Cyclin-G-associated kinaseHomo sapiens (human)Kd0.04341518
Cysteine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000012
Cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)Kd25.600011
Cytochrome c1, heme protein, mitochondrialHomo sapiens (human)Kd30.000012
Cytochrome P450 1A1Homo sapiens (human)EC508.800011
Cytochrome P450 1B1Homo sapiens (human)EC501.100011
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)Kd9.133323
dCTP pyrophosphatase 1Homo sapiens (human)Kd16.527012
Death-associated protein kinase 1Homo sapiens (human)Kd10.000023
Death-associated protein kinase 2Homo sapiens (human)Kd10.000023
Death-associated protein kinase 3Homo sapiens (human)Kd7.116746
Delta(24)-sterol reductaseHomo sapiens (human)Kd30.000013
Deoxycytidine kinaseHomo sapiens (human)Kd30.000012
Discoidin domain-containing receptor 2Homo sapiens (human)Kd18.000035
DNA replication licensing factor MCM4Homo sapiens (human)Kd30.000012
DNA topoisomerase 2-alphaHomo sapiens (human)Kd30.000012
DNA topoisomerase 2-betaHomo sapiens (human)Kd30.000012
DnaJ homolog subfamily A member 1Homo sapiens (human)Kd30.000012
Dual serine/threonine and tyrosine protein kinaseHomo sapiens (human)Kd10.000011
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Kd11.826635
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)Kd10.706835
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)Kd18.000035
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)Kd18.000035
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)Kd11.334023
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)Kd18.000035
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)Kd10.000011
Dual specificity protein kinase CLK1Homo sapiens (human)EC5012.000011
Dual specificity protein kinase CLK1Homo sapiens (human)Kd14.050046
Dual specificity protein kinase CLK2Homo sapiens (human)Kd13.750046
Dual specificity protein kinase CLK3Homo sapiens (human)Kd11.540045
Dual specificity protein kinase CLK4Homo sapiens (human)Kd11.360045
Dual specificity protein kinase TTKHomo sapiens (human)Kd13.963346
Dual specificity testis-specific protein kinase 1Homo sapiens (human)Kd18.000035
Dual specificity testis-specific protein kinase 2Homo sapiens (human)Kd30.000011
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)Kd23.333323
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)Kd13.500034
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)Kd1.300011
Dynamin-like 120 kDa protein, mitochondrialHomo sapiens (human)Kd30.000012
eIF-2-alpha kinase GCN2Homo sapiens (human)Kd3.030023
EKC/KEOPS complex subunit TP53RKHomo sapiens (human)Kd30.000012
Electron transfer flavoprotein subunit betaHomo sapiens (human)Kd30.000011
Elongation factor Tu, mitochondrialHomo sapiens (human)Kd30.000013
endoribonuclease toxin MazFEscherichia coli str. K-12 substr. MG1655EC5099.000022
Ephrin type-A receptor 1Homo sapiens (human)Kd18.000035
Ephrin type-A receptor 2Homo sapiens (human)Kd18.000035
Ephrin type-A receptor 3Homo sapiens (human)Kd3.225034
Ephrin type-A receptor 4Homo sapiens (human)Kd18.000035
Ephrin type-A receptor 5Homo sapiens (human)Kd13.570046
Ephrin type-A receptor 6Homo sapiens (human)Kd2.806746
Ephrin type-A receptor 7Homo sapiens (human)Kd10.700034
Ephrin type-A receptor 8Homo sapiens (human)Kd1.395034
Ephrin type-B receptor 1Homo sapiens (human)Kd6.325034
Ephrin type-B receptor 2Homo sapiens (human)Kd18.000035
Ephrin type-B receptor 3Homo sapiens (human)Kd18.000035
Ephrin type-B receptor 4Homo sapiens (human)Kd12.716746
Ephrin type-B receptor 6Homo sapiens (human)Kd20.566723
Epidermal growth factor receptorHomo sapiens (human)Kd0.06492739
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)Kd14.316035
Eukaryotic translation initiation factor 2-alpha kinase 1Homo sapiens (human)Kd23.333323
Eukaryotic translation initiation factor 5BHomo sapiens (human)Kd30.000011
Exosome RNA helicase MTR4Homo sapiens (human)Kd30.000012
Ferrochelatase, mitochondrialHomo sapiens (human)Kd9.187524
Fibroblast growth factor receptor 1Homo sapiens (human)Kd18.000035
Fibroblast growth factor receptor 2Homo sapiens (human)Kd7.975034
Fibroblast growth factor receptor 3Homo sapiens (human)Kd10.000046
Fibroblast growth factor receptor 4Homo sapiens (human)Kd10.000023
Focal adhesion kinase 1Homo sapiens (human)Kd15.733346
G protein-coupled receptor kinase 4Homo sapiens (human)Kd7.300011
G protein-coupled receptor kinase 6Homo sapiens (human)Kd30.000011
G-protein coupled receptor 35Homo sapiens (human)EC506.975022
General transcription and DNA repair factor IIH helicase subunit XPDHomo sapiens (human)Kd30.000012
Glycine--tRNA ligaseHomo sapiens (human)Kd30.000012
Glycogen phosphorylase, brain formHomo sapiens (human)Kd30.000012
Glycogen phosphorylase, liver formHomo sapiens (human)Kd30.000012
Glycogen synthase kinase-3 alphaHomo sapiens (human)Kd18.000035
Glycogen synthase kinase-3 betaHomo sapiens (human)Kd18.000035
GTP-binding nuclear protein RanHomo sapiens (human)Kd30.000012
Guanine nucleotide-binding protein G(i) subunit alpha-2Homo sapiens (human)Kd30.000012
Heat shock cognate 71 kDa proteinHomo sapiens (human)Kd3.268012
Heme oxygenase 2Homo sapiens (human)Kd30.000012
Hepatocyte growth factor receptorHomo sapiens (human)Kd7.950056
Heterogeneous nuclear ribonucleoprotein A1Homo sapiens (human)Kd5.300012
High affinity nerve growth factor receptorHomo sapiens (human)Kd18.000035
Homeodomain-interacting protein kinase 1Homo sapiens (human)Kd10.000011
Homeodomain-interacting protein kinase 2Homo sapiens (human)Kd5.040022
Homeodomain-interacting protein kinase 3Homo sapiens (human)Kd10.000011
Homeodomain-interacting protein kinase 4Homo sapiens (human)Kd0.960011
Hormonally up-regulated neu tumor-associated kinaseHomo sapiens (human)Kd10.000011
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)Kd10.000011
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)Kd10.000011
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)Kd18.000035
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)Kd30.000012
Insulin receptorHomo sapiens (human)Kd18.000035
Insulin receptor-related proteinHomo sapiens (human)Kd10.000023
Insulin-like growth factor 1 receptorHomo sapiens (human)Kd20.000036
Integrin-linked protein kinaseHomo sapiens (human)Kd30.000012
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)Kd1.500023
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)Kd23.333323
Interleukin-1 receptor-associated kinase 3Homo sapiens (human)Kd18.000035
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)Kd25.000024
Interstitial collagenaseHomo sapiens (human)Kd51.800011
Isoleucine--tRNA ligase, mitochondrialHomo sapiens (human)Kd30.000011
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)Kd3.850022
Leukocyte tyrosine kinase receptorHomo sapiens (human)Kd3.926723
Leukotriene C4 synthaseCavia porcellus (domestic guinea pig)Kd10.000011
LIM domain kinase 1Homo sapiens (human)Kd20.000036
LIM domain kinase 2Homo sapiens (human)Kd20.000036
Long-chain-fatty-acid--CoA ligase 5Homo sapiens (human)Kd30.000011
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)Kd8.100023
Macrophage-stimulating protein receptorHomo sapiens (human)Kd23.333323
MAP kinase-activated protein kinase 2Homo sapiens (human)Kd18.000035
MAP kinase-activated protein kinase 3Homo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 5Homo sapiens (human)Kd15.000034
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd3.793323
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd5.650034
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)Kd18.000035
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)Kd20.000036
Mast/stem cell growth factor receptor KitHomo sapiens (human)Kd6.76361522
Maternal embryonic leucine zipper kinaseHomo sapiens (human)Kd18.000035
Megakaryocyte-associated tyrosine-protein kinaseHomo sapiens (human)Kd10.000011
Membrane-associated progesterone receptor component 1Homo sapiens (human)Kd30.000011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)Kd12.133657
Microtubule-associated serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000011
MidasinHomo sapiens (human)Kd30.000012
Misshapen-like kinase 1Homo sapiens (human)Kd15.650022
Mitogen-activated protein kinase 1Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase 10Homo sapiens (human)Kd16.860035
Mitogen-activated protein kinase 11Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase 12Homo sapiens (human)Kd10.000023
Mitogen-activated protein kinase 13Homo sapiens (human)Kd10.000011
Mitogen-activated protein kinase 14Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase 15Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase 3 Homo sapiens (human)Kd20.000036
Mitogen-activated protein kinase 4Homo sapiens (human)Kd5.000023
Mitogen-activated protein kinase 6Homo sapiens (human)Kd10.000023
Mitogen-activated protein kinase 7Homo sapiens (human)EC505.000011
Mitogen-activated protein kinase 7Homo sapiens (human)Kd11.280068
Mitogen-activated protein kinase 8Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase 9Homo sapiens (human)Kd14.333346
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)Kd4.114723
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)Kd10.000023
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase kinase kinase 12Homo sapiens (human)Kd10.000011
Mitogen-activated protein kinase kinase kinase 13Homo sapiens (human)Kd10.000011
Mitogen-activated protein kinase kinase kinase 15Homo sapiens (human)Kd10.000011
Mitogen-activated protein kinase kinase kinase 19Homo sapiens (human)Kd0.025011
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)Kd20.833323
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)Kd10.415035
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)Kd11.464723
Mitogen-activated protein kinase kinase kinase 4Homo sapiens (human)Kd8.463246
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)Kd18.000035
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)Kd23.333323
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)Kd10.000011
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)Kd10.000023
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)Kd10.273235
Mitogen-activated protein kinase kinase kinase kinase 2Homo sapiens (human)Kd18.070024
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)Kd10.071835
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)Kd16.066035
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)Kd8.342646
Mitotic checkpoint serine/threonine-protein kinase BUB1Homo sapiens (human)Kd20.037713
Multifunctional protein ADE2Homo sapiens (human)Kd30.000012
Muscle, skeletal receptor tyrosine-protein kinaseHomo sapiens (human)Kd10.000023
Myosin light chain kinase 2, skeletal/cardiac muscleHomo sapiens (human)Kd1.910034
Myosin light chain kinase 3Homo sapiens (human)Kd23.333323
Myosin light chain kinase family member 4Homo sapiens (human)Kd10.000023
Myosin light chain kinase, smooth muscleGallus gallus (chicken)Kd10.000012
Myosin light chain kinase, smooth muscleHomo sapiens (human)Kd18.000035
Myosin-10Homo sapiens (human)Kd30.000012
Myosin-14Homo sapiens (human)Kd30.000013
Myosin-IIIaHomo sapiens (human)Kd10.000023
Myosin-IIIbHomo sapiens (human)Kd10.000023
Myotonin-protein kinaseHomo sapiens (human)Kd1.953023
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Homo sapiens (human)Kd30.000013
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)Kd12.025046
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)Kd15.400046
NT-3 growth factor receptorHomo sapiens (human)Kd10.000023
NUAK family SNF1-like kinase 1Homo sapiens (human)Kd10.000023
NUAK family SNF1-like kinase 2Homo sapiens (human)Kd16.540035
Nucleolar GTP-binding protein 1Homo sapiens (human)Kd30.000012
Obg-like ATPase 1Homo sapiens (human)Kd30.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)Kd30.000013
Peripheral plasma membrane protein CASKHomo sapiens (human)Kd10.000011
Peroxisomal acyl-coenzyme A oxidase 1Homo sapiens (human)Kd30.000012
Peroxisomal acyl-coenzyme A oxidase 3Homo sapiens (human)Kd30.000012
Phenylalanine--tRNA ligase beta subunitHomo sapiens (human)Kd30.000012
Phosphatidylethanolamine-binding protein 1Homo sapiens (human)Kd30.000012
Phosphatidylinositol 4-kinase betaHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammaHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaHomo sapiens (human)Kd10.000023
Phosphatidylinositol 4-phosphate 5-kinase type-1 gammaHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)Kd10.00001214
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)Kd10.000011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)Kd10.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaHomo sapiens (human)Kd30.000012
Phosphatidylinositol 5-phosphate 4-kinase type-2 betaHomo sapiens (human)Kd7.533323
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHomo sapiens (human)Kd22.750024
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)Kd15.416746
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformHomo sapiens (human)Kd6.250034
Platelet-derived growth factor receptor alphaHomo sapiens (human)Kd4.533323
Platelet-derived growth factor receptor betaHomo sapiens (human)Kd14.560035
Probable ATP-dependent RNA helicase DDX6Homo sapiens (human)Kd30.000013
Procathepsin LHomo sapiens (human)EC5083.400011
Prostaglandin G/H synthase 2Homo sapiens (human)Kd10.000011
Protein kinase C alpha typeHomo sapiens (human)Kd30.000013
Protein kinase C beta typeHomo sapiens (human)Kd30.000013
Protein kinase C delta typeHomo sapiens (human)Kd16.920035
Protein kinase C epsilon typeHomo sapiens (human)Kd10.000023
Protein kinase C eta typeHomo sapiens (human)Kd10.000023
Protein kinase C iota typeHomo sapiens (human)Kd23.333323
Protein kinase C theta typeHomo sapiens (human)Kd18.000035
Protein kinase C zeta typeHomo sapiens (human)Kd30.000011
Protein-tyrosine kinase 2-betaHomo sapiens (human)Kd18.000035
Protein-tyrosine kinase 6Homo sapiens (human)Kd18.000035
ProthrombinHomo sapiens (human)Kd0.038711
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)Kd9.5099711
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)Kd10.000023
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)Kd9.100047
Putative heat shock protein HSP 90-beta 2Homo sapiens (human)Kd30.000011
Pyridoxal kinaseHomo sapiens (human)Kd30.000012
Rab-like protein 3Homo sapiens (human)Kd30.000012
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)Kd18.000035
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)Kd18.000035
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)Kd20.000036
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)Kd10.000023
Ras-related protein Rab-10Homo sapiens (human)Kd30.000012
Ras-related protein Rab-27AHomo sapiens (human)Kd30.000012
Ras-related protein Rab-6AHomo sapiens (human)Kd30.000012
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)Kd3.715435
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)Kd1.100011
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)Kd0.230011
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000023
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd8.867246
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000012
Receptor-interacting serine/threonine-protein kinase 4Homo sapiens (human)Kd4.900011
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)Kd6.01051319
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirusEC5083.400022
Replicase polyprotein 1abBetacoronavirus England 1EC5083.400011
Replicase polyprotein 1abHuman coronavirus 229EEC5083.400022
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2EC5083.400011
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusEC5083.400022
Rho-associated protein kinase 1Homo sapiens (human)Kd23.333323
Rho-associated protein kinase 2Homo sapiens (human)Kd23.333323
Rhodopsin kinase GRK1Homo sapiens (human)Kd10.000011
Rhodopsin kinase GRK7Homo sapiens (human)Kd10.000011
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)Kd15.000058
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)Kd9.542957
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)Kd18.000035
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)Kd14.250058
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)Kd15.000058
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)Kd15.000058
Ribosomal protein S6 kinase beta-1Homo sapiens (human)Kd23.333323
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)Kd30.000012
RNA cytidine acetyltransferaseHomo sapiens (human)Kd30.000012
S-adenosylmethionine synthase isoform type-2Homo sapiens (human)Kd30.000013
Septin-9Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase 10Homo sapiens (human)Kd0.670858
Serine/threonine-protein kinase 16Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase 17AHomo sapiens (human)Kd4.139234
Serine/threonine-protein kinase 17BHomo sapiens (human)Kd6.225034
Serine/threonine-protein kinase 24Homo sapiens (human)Kd7.366723
Serine/threonine-protein kinase 25Homo sapiens (human)Kd7.800023
Serine/threonine-protein kinase 26Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase 3Homo sapiens (human)Kd16.480035
Serine/threonine-protein kinase 3Mus musculus (house mouse)Kd1.100011
Serine/threonine-protein kinase 32AHomo sapiens (human)Kd10.000011
Serine/threonine-protein kinase 32BHomo sapiens (human)Kd8.666723
Serine/threonine-protein kinase 32CHomo sapiens (human)Kd10.000023
Serine/threonine-protein kinase 33Homo sapiens (human)Kd8.166723
serine/threonine-protein kinase 33 isoform aHomo sapiens (human)EC5012.790011
Serine/threonine-protein kinase 35Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase 36Homo sapiens (human)Kd4.900034
Serine/threonine-protein kinase 38Homo sapiens (human)Kd20.000022
Serine/threonine-protein kinase 38-likeHomo sapiens (human)Kd12.620045
Serine/threonine-protein kinase 4Homo sapiens (human)Kd14.583346
Serine/threonine-protein kinase A-RafHomo sapiens (human)Kd30.000012
Serine/threonine-protein kinase ATRHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase B-rafHomo sapiens (human)Kd15.000058
Serine/threonine-protein kinase BRSK1Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase BRSK2Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase Chk1Homo sapiens (human)Kd16.380035
Serine/threonine-protein kinase Chk2Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase D1Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase D2Homo sapiens (human)Kd20.000036
Serine/threonine-protein kinase D3Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase DCLK1Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase DCLK2Homo sapiens (human)Kd7.547534
Serine/threonine-protein kinase DCLK3Homo sapiens (human)Kd8.300023
Serine/threonine-protein kinase ICKHomo sapiens (human)Kd23.333323
Serine/threonine-protein kinase LATS1Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase LATS2Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase MAKHomo sapiens (human)Kd10.000011
Serine/threonine-protein kinase MARK1Homo sapiens (human)Kd8.000023
Serine/threonine-protein kinase MARK2Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)Kd18.000035
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)Kd18.000035
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)Kd15.360035
Serine/threonine-protein kinase mTORHomo sapiens (human)Kd10.000011
Serine/threonine-protein kinase N1Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase N2Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase N3Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase Nek1Homo sapiens (human)Kd16.780035
Serine/threonine-protein kinase Nek11Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase Nek2Homo sapiens (human)Kd13.470046
Serine/threonine-protein kinase Nek3Homo sapiens (human)Kd23.333323
Serine/threonine-protein kinase Nek4Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase Nek5Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase Nek6Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase Nek7Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase Nek9Homo sapiens (human)Kd20.000036
Serine/threonine-protein kinase NIM1Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase NLKHomo sapiens (human)Kd18.000035
Serine/threonine-protein kinase OSR1Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase PAK 1Homo sapiens (human)Kd6.375034
Serine/threonine-protein kinase PAK 2Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase PAK 3Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase PAK 5Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase PAK 6Homo sapiens (human)Kd15.000034
Serine/threonine-protein kinase pim-1Homo sapiens (human)Kd12.872157
Serine/threonine-protein kinase pim-2Homo sapiens (human)Kd15.013346
Serine/threonine-protein kinase pim-3Homo sapiens (human)Kd7.520034
Serine/threonine-protein kinase PknBMycobacterium tuberculosis H37RvKd10.000011
Serine/threonine-protein kinase PLK1Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase PLK2Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase PLK3Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase PLK4Homo sapiens (human)Kd13.750046
Serine/threonine-protein kinase PRP4 homologHomo sapiens (human)Kd10.000011
Serine/threonine-protein kinase receptor R3Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase RIO1Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase RIO2Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase RIO3Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase SBK1Homo sapiens (human)Kd1.200011
Serine/threonine-protein kinase Sgk3Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase SIK1Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase SIK2Homo sapiens (human)Kd15.420035
Serine/threonine-protein kinase SIK3Homo sapiens (human)Kd23.333323
Serine/threonine-protein kinase STK11Homo sapiens (human)Kd18.000035
Serine/threonine-protein kinase TAO1Homo sapiens (human)Kd23.333323
Serine/threonine-protein kinase TAO2Homo sapiens (human)Kd23.333323
Serine/threonine-protein kinase TAO3Homo sapiens (human)Kd23.333323
Serine/threonine-protein kinase TBK1Homo sapiens (human)Kd21.033323
Serine/threonine-protein kinase TNNI3KHomo sapiens (human)Kd2.780023
Serine/threonine-protein kinase tousled-like 1Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase tousled-like 2Homo sapiens (human)Kd10.000023
Serine/threonine-protein kinase ULK1Homo sapiens (human)Kd23.333323
Serine/threonine-protein kinase ULK2Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase ULK3Homo sapiens (human)Kd20.306723
Serine/threonine-protein kinase ULK3Mus musculus (house mouse)Kd2.215012
Serine/threonine-protein kinase VRK2Homo sapiens (human)Kd10.000011
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)Kd25.000024
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)Kd30.000012
SNF-related serine/threonine-protein kinaseHomo sapiens (human)Kd10.000011
Spike glycoproteinBetacoronavirus England 1EC5083.400011
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusEC5083.400011
SRSF protein kinase 1Homo sapiens (human)Kd10.000023
SRSF protein kinase 2Homo sapiens (human)Kd10.000023
SRSF protein kinase 3Homo sapiens (human)Kd8.300011
STE20-like serine/threonine-protein kinase Homo sapiens (human)Kd4.609047
STE20-related kinase adapter protein alphaHomo sapiens (human)Kd30.000012
STE20/SPS1-related proline-alanine-rich protein kinaseHomo sapiens (human)Kd10.000011
Structural maintenance of chromosomes protein 1AHomo sapiens (human)Kd30.000012
Structural maintenance of chromosomes protein 2Homo sapiens (human)Kd30.000012
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrialHomo sapiens (human)Kd30.000011
Testis-specific serine/threonine-protein kinase 1Homo sapiens (human)Kd10.000023
TGF-beta receptor type-1Homo sapiens (human)Kd20.000036
TGF-beta receptor type-2Homo sapiens (human)Kd18.000035
Thyroid hormone receptor-associated protein 3Homo sapiens (human)Kd30.000012
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)Kd7.669246
Transient receptor potential cation channel subfamily M member 6Homo sapiens (human)Kd10.000011
Transmembrane protease serine 2Homo sapiens (human)EC5083.400011
Tubulin alpha-1A chainRattus norvegicus (Norway rat)Kd0.125512
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000012
Tyrosine-protein kinase ABL1Homo sapiens (human)Kd1.31683146
Tyrosine-protein kinase ABL2Homo sapiens (human)Kd8.747147
Tyrosine-protein kinase BlkHomo sapiens (human)Kd0.152723
Tyrosine-protein kinase BTKHomo sapiens (human)Kd9.485746
Tyrosine-protein kinase CSKHomo sapiens (human)Kd14.216746
Tyrosine-protein kinase FerHomo sapiens (human)Kd14.841746
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)Kd17.140035
Tyrosine-protein kinase FgrHomo sapiens (human)Kd8.287534
Tyrosine-protein kinase FRKHomo sapiens (human)Kd9.294357
Tyrosine-protein kinase FynHomo sapiens (human)Kd14.000046
Tyrosine-protein kinase HCKHomo sapiens (human)Kd6.563346
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)Kd7.500023
Tyrosine-protein kinase JAK1Homo sapiens (human)Kd16.666746
Tyrosine-protein kinase JAK2Homo sapiens (human)Kd6.425034
Tyrosine-protein kinase JAK3Homo sapiens (human)Kd0.551723
Tyrosine-protein kinase LckHomo sapiens (human)Kd7.712958
Tyrosine-protein kinase LynHomo sapiens (human)Kd10.456746
Tyrosine-protein kinase MerHomo sapiens (human)Kd14.456035
Tyrosine-protein kinase receptor Tie-1Homo sapiens (human)Kd0.900023
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)Kd3.833323
Tyrosine-protein kinase receptor UFOHomo sapiens (human)Kd4.973323
Tyrosine-protein kinase SrmsHomo sapiens (human)Kd10.000023
Tyrosine-protein kinase SYKHomo sapiens (human)EC5021.666733
Tyrosine-protein kinase SYKHomo sapiens (human)Kd16.914347
Tyrosine-protein kinase TecHomo sapiens (human)Kd20.000036
Tyrosine-protein kinase TXKHomo sapiens (human)Kd6.433323
Tyrosine-protein kinase YesHomo sapiens (human)Kd11.056746
Tyrosine-protein kinase ZAP-70Homo sapiens (human)Kd10.000023
U5 small nuclear ribonucleoprotein 200 kDa helicaseHomo sapiens (human)Kd30.000012
UMP-CMP kinase Homo sapiens (human)Kd30.000011
Uncharacterized aarF domain-containing protein kinase 5Homo sapiens (human)Kd30.000012
Uncharacterized protein FLJ45252Homo sapiens (human)Kd30.000012
Uncharacterized serine/threonine-protein kinase SBK3Homo sapiens (human)Kd10.000011
Vascular endothelial growth factor receptor 1 Homo sapiens (human)Kd6.266723
Vascular endothelial growth factor receptor 2Homo sapiens (human)Kd8.566723
Vascular endothelial growth factor receptor 3Homo sapiens (human)Kd4.733323
Very long-chain specific acyl-CoA dehydrogenase, mitochondrialHomo sapiens (human)Kd30.000012
Wee1-like protein kinaseHomo sapiens (human)Kd8.651546
Wee1-like protein kinase 2Homo sapiens (human)Kd5.249022

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Cyclin-A1Homo sapiens (human)ID500.006011
Cyclin-A2Homo sapiens (human)ID500.006011
Cyclin-dependent kinase 2Homo sapiens (human)ID500.007522
dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)AC507.534011
FAD-linked sulfhydryl oxidase ALRHomo sapiens (human)AC500.689011
G1/S-specific cyclin-E1Homo sapiens (human)ID500.009011
G1/S-specific cyclin-E2Homo sapiens (human)ID500.009011
glycogen synthase kinase-3 alphaHomo sapiens (human)AC5038.780011
interferon gamma precursorHomo sapiens (human)AC5016.690022
Polyphenol oxidase 2Agaricus bisporusID5070.000011
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)Km114.800022
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)Vmax0.007022
Xanthine dehydrogenase/oxidaseBos taurus (cattle)Km65.300044