The last menstrual period. Permanent cessation of menses (MENSTRUATION) is usually defined after 6 to 12 months of AMENORRHEA in a woman over 45 years of age. In the United States, menopause generally occurs in women between 48 and 55 years of age.
Excerpt | Reference |
"Menopause is merely a clinically discernible clue symbolic of the multitude of changes preceding or following the cessation of menses by many years." | ( Archer, DF; Detre, T; Hayashi, TT, 1978) |
"Menopause is a time of psychologic adjustment as well as of physical change." | ( Gruis, ML; Wagner, NN, 1979) |
"As the menopause is approached, urinary excretion of estrogens gradually diminishes and the cyclic fluctuation becomes more shallow." | ( Iwamura, K, 1979) |
"Estrogen loss at menopause is thus associated with an apparent partial release from an inhibition of skeletal resorption, and this release is, in whole or part, responsible for the negative skeletal balance shift associated with the postmenopausal years." | ( Heaney, RP; Recker, RR; Saville, PD, 1978) |
"It appears that the menopause is preceded by several years of rising gonadotropin, predominantly FSH, levels." | ( Faiman, C; Reyes, FI; Winter, JS, 1977) |
"The menopause is a fact of life for every woman, and how it affects her depends on her physiologic makeup and on her emotional health." | ( Banner, EA, 1976) |
"The menopause is centered on the ovary and its in-built obsolescence." | ( Mason, AS, 1976) |
"Premature menopause is associated with adverse lipid changes and an increased risk of coronary heart disease." | ( Barnes, JF; Farish, E; Fletcher, CD; Gray, CE; Hart, DM; Mack, A, 1992) |
"The menopause is associated with a rise in obligatory urinary calcium loss resulting from an increase in the filtered load of calcium which may be due to the complexed fraction." | ( Horowitz, H; Morris, HA; Need, AG; Nordin, BE; Polley, KJ, 1988) |
"Although the menopause is generally considered to be the consequence of follicular exhaustion, the relationship between follicle number and the menopausal transition has not been explicity studied." | ( Nelson, JF; Richardson, SJ; Senikas, V, 1987) |
"The menopause is the physiologic cessation of normal, cyclic ovarian function." | ( Cheang, A; Kottegoda, SR; Ratnam, SS, 1987) |
"Menopause is not inevitably a time of increased depression or nervous symptomatology." | ( Nolan, JW, 1986) |
"Since menopause is increasingly implicated in the etiology of some major age-related diseases in women, such as cancer, cardiovascular disease, osteoporosis, and depression, there is a need to understand the epidemiology of this physiologic event which is universal for women." | ( Brambilla, DJ; McKinlay, JB; McKinlay, SM, 1987) |
"Entry into menopause is associated with a severe diminution of ovarian estrogen and progesterone secretion and a reduction of circulating androgens, although, in the presence of ovaries, a degree of testosterone secretion persists." | ( Korenman, SG, 1982) |
"Menopause is associated with anatomical, physiological and psychological changes that often influence sexuality in the aging female." | ( Bachmann, GA, 1995) |
"Natural menopause is not associated with large changes in other risk factors in this sample." | ( Broda, G; Davis, CE; Ephross, S; Pajak, A; Pazucha, T; Rywik, S; Williams, DH, 1994) |
"The menopause is defined rigorously as the cessation of menstruation as a result of ovarian follicular depletion." | ( Burger, HG, 1994) |
"Menopause is associated with a gain in fat mass and a loss of lean body mass, but these changes in body composition are not prevented by hormone replacement therapy." | ( Aloia, JF; Flaster, E; Russo, L; Sheehan, M; Vaswani, A, 1995) |
"Menopause is associated with enhanced stress-induced cardiovascular responses and elevated ambulatory blood pressure during the workday." | ( Matthews, KA; Owens, JF; Stoney, CM, 1993) |
"Occurrence of menopause is rare before age 35, and it increases with the age of the female irrespective of religion or caste." | ( Bhattacharya, B; Singh, KK; Singh, U, 1995) |
"Although the perimenopause is associated with increases in baseline and stimulated gonadotropin levels similar to those seen after the menopause, significantly increased baseline luteinizing hormone bioactivity and the bioactivity/immunoactivity ratio are seen only after the menopause." | ( Baron, DA; Gindoff, PR; Rubinow, DR; Schmidt, PJ, 1996) |
"Menopause is marked by the permanent cessation of menstrual bleeding." | ( Ottesen, B; Pedersen, AT, 1996) |
"In conclusion, menopause is not characterized by altered levels of thyroid hormones or altered skeletal responsiveness to thyroid hormones." | ( Charles, P; Eriksen, EF; Langdahl, BL; Loft, AG; Mosekilde, L; Møller, N; Weeke, J, 1996) |
"Menopause is not a disease, but it can be associated with discomfort, a decreased quality of life, and an increase in the disease risks of osteoporosis and coronary heart disease." | ( Thacker, HL, 1997) |
"Menopause is associated with a reduction in melatonin which may relate to the changing gonadotropin levels." | ( Reiter, RJ, 1998) |
"Menopause is primary determined by the estrogen deficit." | ( Meczekalski, B; Warenik-Szymankiewicz, A, 1997) |
"Menopause is an expected event in a woman's life." | ( Barton, DL; Finck, G; Loprinzi, CL; Quella, SK; Sloan, JA, 1998) |
"Surgical menopause is able to affect short-term verbal memory more than physiological menopause and seems to represent a critical negative event within the female brain, in particular when it occurs prematurely." | ( Bono, G; Mauri, M; Nappi, G; Nappi, RE; Polatti, F; Sinforiani, E, 1999) |
"Menopause is associated with increased neurokinin B (NKB) gene expression and decreased proopiomelanocortin (POMC) gene expression in the human hypothalamus." | ( Abel, TW; Rance, NE; Voytko, ML, 1999) |
"Natural menopause is associated with aggravated postprandial lipemia in women matched for age and body mass index." | ( de Bruin, TW; de Ruijter-Heijstek, FC; Erkelens, DW; van Beek, AP, 1999) |
"Menopause is a physiologic event that gives a woman the opportunity to become involved in a preventive health program." | ( Kothari, S; Thacker, HL, 1999) |
"The menopause is associated with a decrease in the resting metabolic rate that reduces the utilisation of calories and hence increases body weight." | ( van Seumeren, I, 2000) |
"Menopause is associated with impaired arterial endothelial function in Caucasian but not Chinese women." | ( Celermajer, DS; McCrohon, JA; Woo, KS, 2000) |
"Menopause is characterized by a decreased expression of the obese gene, even if estrogens do not seem to represent a main causal factor." | ( Cento, RM; Ciampelli, M; Cucinelli, F; Lanzone, A; Napolitano, V; Proto, C; Spada, RS, 1999) |
"Menopause is a physiological event." | ( Morris, EP; Rymer, J, 2000) |
"Natural menopause is associated with profound biochemical and metabolic changes, which are established risk factors, e." | ( Gohlke-Bärwolf, C, 2000) |
"Menopause is a natural event, and understandably many women would like to take a natural therapy rather than a drug for managing their menopause symptoms as well as preventing the long-term sequelae of oestrogen deficiency." | ( Eden, JA, 2001) |
"'Early perimenopause' is defined as the self-reporting of changes in menstrual frequency over the last year, and 'late perimenopause' is defined as the self-report of 3-11 months of amenorrhea." | ( Burger, HG; Dennerstein, L; Dudley, EC; Guthrie, JR; Hopper, JL; Taffe, J, 1998) |
"The menopause is the permanent cessation of menstruation resulting from the loss of ovarian follicular activity." | ( Burger, HG; Dennerstein, L; Dudley, EC; Robertson, DM, 2002) |
"Menopause is a natural event in a woman's life cycle and loss of libido may be one of a multitude of symptoms experienced around this time." | ( Reddish, S, 2002) |
"Management of the menopause is a rapidly growing concern due to the ageing human population." | ( Eichholz, AC; Mahavni, V; Sood, AK, 2002) |
"Menopause is the period during which serious health problems such as cardiovascular diseases and osteoporosis occur with increasing frequency." | ( Biela, U, 2002) |
"Perimenopause is characterized by irregular menstrual cycles, and by the appearance of the so called hot flashes." | ( Netter, A, 1979) |
"The age of menopause is also increasing." | ( Aziz, NL, 1980) |
"Menopause is a time of anatomic, physiological and psychological changes that often influence in the sexuality of aging female." | ( Menendez, C; Palacios, S; Tobar, AC, 2002) |
"Aging and menopause are associated with alterations of the sleep EEG, while age-related changes of the hypothalamo-pituitary-adrenal (HPA) axis remain controversial." | ( Antonijevic, IA; Frieboes, RM; Murck, H; Steiger, A; Uhr, M, 2003) |
"Earlier onset of menopause is associated with an increased risk for cardiovascular disease, especially among women with surgical menopause." | ( Curhan, GC; Kramer, HM; Singh, A, 2003) |
"Menopause is associated with insomnia due to several factors including hot flashes, mood disorders and increased sleep-disordered breathing." | ( Broch, L; Gross, V; Moline, ML; Zak, R, 2003) |
"Late-onset of menopause is a marker of risk factor for neoplasia in the reproductive system and, conversely, anti-risk for certain non-infectious diseases, such as cardio-vascular disease or osteoporosis." | ( Bershteĭn, DM; Chernobrovkina, AE; Gamaiunova, VB; Kovalenko, IG; Kvachevskaia, IuO; Tsyrlina, EV, 2003) |
"The menopause is emerging as an issue owing to rapid globalization, urbanization, awareness and increased longevity in urban middle-aged Indian women, who are evolving as a homogeneous group." | ( Sengupta, A, 2003) |
"Perimenopause is a transition during which women with epilepsy are at risk for increased seizure frequency, probably because of alterations in the estrogen:progesterone ratio over this period." | ( Harden, CL, 2003) |
"Menopause is recognized as a period of increased risk for coronary heart disease (CHD) and osteoporosis." | ( Kaplan, JR; Manuck, SB, 2004) |
"The onset of human menopause is thought to be caused solely by ovarian failure and oocyte depletion." | ( Goldsmith, LT; Park, SJ; Santoro, NF; Skurnick, JH; Weiss, G, 2004) |
"The menopause is associated with an increase in oxidative stress and a decrease of some antioxidants, such as ascorbic acid, alpha-tocopherol, total thiols and erythrocyte GSH." | ( Akgül, C; Canbaz, M; Vural, P, 2005) |
"Menopause is associated with a significant decline in levels of estrogen, which reportedly leads to several distressing symptoms and adverse health effects on various target tissues including those on bones, heart, and brain." | ( Asthana, S; Atwood, C; Carlsson, CM; Gleason, CE; Johnson, S, 2005) |
"Menopause is one of the most common risk factors of osteoporosis." | ( Arjmandi, B; Hossein-Nezhad, A; Kimiagar, SM; Larijani, B; Roudsari, AH; Tahbaz, F, 2005) |
"Menopause is a normal milestone experienced annually by 2 million American women each year, and many women are concerned about the relation between menopause and health." | ( Henderson, VW, 2006) |
"Women with an early menopause are at an increased risk of cardiovascular disease." | ( Grobbee, DE; Kok, HS; Pearson, PL; Peeters, PH; van Asselt, KM; van der Schouw, YT; van der Tweel, I; Wilson, PW, 2006) |
"Age at natural menopause is related to several health outcomes, including cardiovascular disease and overall mortality." | ( Adam, E; Hartge, P; Hatch, EE; Herbst, AL; Hoover, RN; Hyer, M; Kaufman, R; Noller, KL; Palmer, JR; Robboy, S; Strohsnitter, W; Titus-Ernstoff, L; Troisi, R; Wise, LA, 2006) |
"Menopause is a physiologic transition and is assuming an increasing importance as the demographic bulge moves through this phase." | ( Blake, J, 2006) |
"Menopause is a risk factor for cardiovascular disease (CVD) because estrogen withdrawal has a detrimental effect on cardiovascular function and metabolism." | ( Marazzi, G; Rosano, GM; Vitale, C; Volterrani, M, 2007) |
"Menopause is a natural process that occurs in women's lives as part of normal aging." | ( Tuchman, E, 2007) |
"The perimenopause is associated with hormonal fluctuations and may worsen the epilepsy in women with catamenial epilepsy." | ( Gjerstad, L; Røste, LS; Svalheim, S; Taubøll, E, 2008) |
"Menopause is the time of life when menstrual cycles cease, and is caused by reduced secretion of the ovarian hormones oestrogen and progesterone." | ( Nelson, HD, 2008) |
"Menopause is characterized by depletion of ovarian follicles, a reduction of ovarian hormones to castrate levels and elevated levels of serum gonadotropins." | ( Rance, NE, 2009) |
"The natural menopause is not associated with substantial cognitive change." | ( Henderson, VW, 2008) |
"Menopause is associated with sharp declines in concentrations of circulating estrogens." | ( Henderson, VW, 2010) |
"Menopause is recognized as a period of increased risk for coronary heart disease." | ( Brito, S; Consolim-Colombo, F; De Angelis, K; Flues, K; Irigoyen, MC; Paulini, J; Sanches, IC, 2010) |
"Menopause is associated with an increased risk of cardiovascular and metabolic disease that is partly independent of aging." | ( Bolego, C; Cignarella, A; Kratz, M, 2010) |
"Menopause is associated with adverse metabolic changes, especially in plasma lipoprotein and cholesterol levels." | ( Dotlic, J; Maricic, S; Mihailovic, T; Terzic, MM; Tosic-Race, B, 2009) |
"As menopause is associated with increased blood pressure, inflammation and oxidative stress, tibolone restores blood pressure and has beneficial effect on inflammation and glycemia without worsening oxidative stress, although it also reduces HDL levels." | ( Battaglia, D; Cicinelli, E; Lello, S; Maffei, S; Mercuri, A; Vassalle, C, 2011) |
"The transition into menopause is a complex process that affects fertility and increases the risk for a number of health problems in aging women that include, but are not limited to osteoporosis, heart disease, diabetes mellitus and cognitive dysfunction." | ( Dicken, C; Neal-Perry, G; Nejat, E, 2010) |
"Menopause is associated with increased cardiovascular risk factors." | ( Cakir, C; Cakir, E; Küçüközkan, T; Okuyan, E; Özkaya, E; Ustün, G, 2011) |
"Thus, menopause is a critical phase for FSD complaints." | ( Andersen, ML; Hachul, H; Mazaro-Costa, R; Tufik, S, 2010) |
"Menopause is the descent in circulating estrogens that manifests clinically for the climacteric symptoms." | ( Basurto, L; Córdova-Pérez, N; Hernández-Valencia, M; Manuel, L; Ruiz, M; Saucedo, R; Vargas, A; Vargas, C; Zárate, A, 2010) |
"Natural menopause is a normal physiological process that can only be directly studied through observational research." | ( Henderson, VW, 2011) |
"Menopause is a consequence of reproductive aging and follicular depletion (ovarian failure), yielding very low circulating estrogen serum concentrations and biologically disadvantageous metabolic alterations." | ( Naftolin, F; Pollycove, R; Simon, JA, 2011) |
"DISCUSSION Menopause is characterized by increased levels of IL-2, which has critical immune-modulatory effects." | ( Akyol, S; Aydinli, K; Cınar, SA; Purisa, S, 2011) |
"Menopause is a physiological event." | ( Burbos, N; Morris, EP, 2010) |
"Menopause is associated with central obesity, dyslipidemia, hypertension and insulin resistance, which are also shown in the patients with excess of glucocorticoids." | ( Cai, Y; Chen, Q; Huang, R; Li, S; Liu, W; Wang, L; Wu, Y, 2011) |
"The menopause is a time in a woman's life when it is recognized that biological and social changes can impact upon mental wellbeing." | ( Dening, T; Sandilyan, MB, 2011) |
"Early menopause is a risk factor for rheumatoid arthritis, and post-menopausal status in RA is associated with greater damage and disability." | ( Sammaritano, LR, 2012) |
"The menopause is a period in which significant changes in oestrogen levels are recorded, and this review discusses studies that help to clarify the link between menopause and the perception of thinning hair." | ( Mirmirani, P, 2011) |
"Menopause is a unique phenomenon in modern women, as most mammalian species possess a reproductive period comparable with their life span." | ( Cai, KQ; Miki, RA; Smedberg, JL; Smith, ER; Wei, JQ; Xu, XX; Yang, WL; Yeasky, T, 2012) |
"Menopause is associated with changes in bone, muscle and fat mass." | ( Armamento-Villareal, RC; Giri, TK; Napoli, N; Nekkalapu, S; Qualls, C; Vattikuti, S; Yarramaneni, J, 2012) |
"The transition to menopause is associated with an increased risk of depressed mood." | ( Bazanella Sampaio, T; Mozzaquatro Gai, B; Nogueira, CW; Pinton, S; Trevisan da Rocha, J; Zeni, G, 2012) |
"Menopause is characterized by amenorrhea for 1 year due to the cessation of ovarian function." | ( Eyster, KM; Hansen, KA, 2012) |
"Human menopause is ubiquitous among women and is uninfluenced by modernity." | ( Gillespie, DOS; Lahdenperä, M; Lummaa, V; Russell, AF, 2012) |
"Menopause is associated with endothelial dysfunction and oxidative stress." | ( Barazzoni, R; Biolo, G; Carretta, R; Fabris, B; Gortan Cappellari, G; Jevnicar, M; Losurdo, P; Macaluso, L; Mazzucco, S; Panizon, E; Zanetti, M, 2013) |
"Menopause is an important stage in the life of every woman." | ( Khaleghinezhad, K; Menati, L; Siahpoosh, A; Tadayon, M, 2014) |
"Menopause is a physiological event of women's life that is the end of menstrual cycles and the end of the fertile period." | ( Caldaci, LM; Catavorello, A; Fichera, M; La Rosa, B; Panella, MM; Rinaldi, N; Tarascio, M; Taschetta, S, 2013) |
"Menopause is the interruption of menstrual and reproductive capacity, therefore, that occurs naturally in all women between 48 and 55 years, due to a lower production of gonadal steroids." | ( Ambrosio, D; Ammaturo, FP; De Franciscis, P; La Rezza, F; Labriola, D; Schettino, MT; Torella, M; Trotta, C; Zarcone, R, 2013) |
"Menopause is the permanent cessation of menstruation that results from depletion of ovarian germ cells and follicles." | ( Cai, KQ; Smedberg, J; Smith, ER; Xu, XX; Yang, WL; Yeasky, T, 2013) |
"Menopause is a normal part of a woman's lifecycle and consists of a series of body changes that can last from one to ten years." | ( Ghosh, M; Rodriguez-Garcia, M; Wira, CR, 2014) |
"Menopause is a key point moment in the specific aging process of women." | ( Berardesca, E; Gaspard, U; Hermanns-Lê, T; Humbert, P; Piérard, GE; Piérard-Franchimont, C, 2013) |
"Menopause is characterized by an altered hormonal status and by a decrease in life quality due to the appearance of uncomfortable symptoms." | ( Moreira, AC; Santos, MS; Sardão, VA; Silva, AM, 2014) |
"Menopause is a natural change in a women's life, the menopause-related low estrogen levels affecting many body functions, among them the immune system." | ( Daniilidis, A; Iliodromiti, Z; Kalantaridou, S; Valsamakis, G; Vrachnis, N; Zygouris, D, 2014) |
"Menopause is associated with increased visceral adiposity and disrupted glucose homeostasis, but the underlying molecular mechanisms related to these metabolic changes are still elusive." | ( Barthem, CS; Carvalho, DP; de Meis, L; Fortunato, RS; Ketzer, LA; Louzada, RA; Nigro, M; Santos, AT, 2014) |
"Menopause is associated with disc degeneration in the lumbar spine." | ( Chen, HL; Fang, MQ; Feng, XZ; Jin, YL; Lou, C; Tian, NF; Wang, C; Xiang, GH; Xu, HZ; Zhu, SP, 2014) |
"Menopause is a crucial time in the life of any women." | ( Isaeva, AS; Vovchenko, MN, 2014) |
"Early menopause is associated with greater NT-proBNP levels, whereas each 1-year increase in menopause age is associated with lower NT-proBNP levels, in postmenopausal women." | ( Bertoni, AG; Bluemke, DA; Ebong, IA; Goff, DC; Horwich, T; Srikanthan, P; Watson, KE, 2015) |
"Menopause is the stage when the menstrual period permanently stops, and is a part of every woman's life." | ( Jayabharathi, B; Judie, A, 2014) |
"Menopause is caused by changes in the function of the hypothalamic-pituitary-gonadal axis that controls reproduction." | ( Gore, AC; Naugle, MM, 2014) |
"In women, menopause is associated with increased risk of memory disturbances, which can be attenuated by timely estrogen therapy." | ( Auer, H; Hrabovszky, E; Kalló, I; Liposits, Z; Rodolosse, A; Sárvári, M; Solymosi, N; Vastagh, C, 2015) |
"Menopause is a significant physiological phase that occurs as women's ovaries stop producing ovum and the production of estrogen declines." | ( Han, NR; Jeong, HJ; Kim, HM; Kim, HY; Kim, NR; Moon, PD; Nam, SY; Park, CL; Yoou, MS, 2015) |
"Menopause is a turning point in a woman's life." | ( Brończyk, AP; Dittfeld, A; Gwizdek, K; Koszowska, A; Nowak, J; Zubelewicz-Szkodzińska, B, 2015) |
"Menopause is associated with higher plasma and liver triacylglycerol (TAG) and increased risk for cardiovascular disease." | ( Aristizabal Henao, JJ; Kitson, AP; Marks, KA; Stark, KD; Tupling, AR, 2015) |
"Menopause is an endocrinological transition that greatly affects health and disease susceptibility in middle-aged and elderly women." | ( Guo, B; Hou, Y; Ke, C; Li, H; Li, K; Li, Y; Wang, J; Yang, K; Zhang, F; Zhang, H; Zhou, X, 2015) |
"Menopause is a critical stage in every woman's life." | ( Abdi, F; Kazemi, F; Ramezani Tehrani, F; Roozbeh, N, 2016) |
"Menopause is accompanied by enhanced oxidative stress and behavioral changes, effects attenuated by antioxidants." | ( Caravan, I; Decea, N; Filip, GA; Moldovan, R; Orasan, R; Sevastre Berghian, A, 2016) |
"Menopause is a period of higher depressive vulnerability." | ( Huang, S; Liu, C; Liu, X; Ye, Y, 2016) |
"Menopause is characterized by dramatically decreased circulating estrogen level secondary to loss of ovarian function and atrophic state of genital organs." | ( Wei, Y; Yi, T; Zhao, L; Zhao, X; Zhou, S, 2016) |
"Menopause is associated with increased bone resorption and decreased bone mineral density (BMD)." | ( Abdi, F; Alimoradi, Z; Haqi, P; Mahdizad, F, 2016) |
"Menopause is for many females associated with an occurrence of a variety of health complaints and a decrease in quality in life." | ( Diel, P; Hanke, L; Kurrat, A; Oden, C, 2017) |
"Menopause is a cardiovascular risk factor in women, and cardiovascular changes during perimenopause can increase the risk." | ( Bai, W; Jia, J; Jiang, H; Liu, S; Liu, Y; Qin, L; Wang, K; Wang, W; Zhang, J, 2017) |
"Menopause is an important time for middle aged women and postmenopausal physiological changes could have a significant role in the development of FSD." | ( Borghi, C; Dell'Atti, L, 2017) |
"Menopause is associated with adverse changes in hematological parameters." | ( Arjmandi, BH; Chai, SC; Feresin, RG; Johnson, SA; Keshavarz, B; Khalil, DA; Pourafshar, S, 2018) |
"Menopause is the most important sign of aging in women, and the ovary is the organ most sensitive to aging." | ( Gao, Q; Jin, H; Lv, C; Qian, X; Wang, J; Xu, J; Zhu, H, 2018) |
"Menopause is associated with adverse effects on quality of life of perimenopausal and post-menopausal women." | ( Ampatzi, C; Goulis, DG; Mareti, E; Paschou, SA; Voziki, E, 2019) |
"Menopause is a critical period during which, without timely interventions, increased risks of cardiovascular and metabolic diseases, osteoporosis, sexual dysfunction and premature cognitive decline will contribute to diminished quality-of-life in women." | ( Howe, PRC; Thaung Zaw, JJ; Wong, RHX, 2018) |
"Obesity and menopause are independent negative predictors of plasma oxytocin." | ( Aimaretti, G; Castello, L; Di Blasio, A; Maestrini, S; Mai, S; Marzullo, P; Mele, C; Scacchi, M; Surico, D; Vietti, R, 2018) |
"Menopause is the cessation of menstruation due to loss of ovarian function and is diagnosed retrospectively after 12 consecutive months of amenorrhea." | ( Bain, J; Bradford, S; Bragg, S; Ramsetty, A, 2018) |
"Menopause is associated with dyslipidemia and an increased risk of cardio-cerebrovascular disease." | ( Bo, T; Chen, W; Cui, M; Gao, L; Guan, Q; Guo, Y; He, Z; Hou, X; Li, Q; Li, Y; Lin, X; Lin, Y; Liu, J; Liu, L; Ma, S; Qi, X; Song, Y; Wang, L; Wang, Q; Xuan, S; Yan, H; Yang, Z; Yu, C; Yuan, Z; Zhang, H; Zhang, Z; Zhao, J; Zhao, L; Zhao, M; Zhu, Q, 2019) |
"Menopause is associated with increased oxidative stress and memory impairment." | ( Allahtavakoli, M; Delrobaei, F; Fatemi, I; Shamsizadeh, A, 2019) |
""Menopause is an event in life, not a disease"." | ( Devi, SK, 2016) |
"Menopause is the universal physiological process of women's midlife and exhibits a wide variety of symptoms." | ( Kaur, M; Sinha, AK; Thakur, M, 2019) |
"Menopause is considered the major determinant of blood pressure rise in women." | ( Casiglia, E; Gasparotti, F; Spinella, P; Tikhonoff, V, 2019) |
"Menopause is an important physiological event associated with structural and functional changes in the kidneys." | ( Abdallah, HI; El-Gendy, AA; Elsaed, WM, 2019) |
"Menopause is closely associated with the risk of anxiety and depression in a woman's life." | ( Shi, DD; Zhang, ZJ; Zhou, XD, 2019) |
"Menopause is a product of interrupted ovarian activity and decrease in its estradiol production." | ( Badehnoosh, B; Emaminia, F; Ramezani, R; Rezaei, A; Shabani, M, 2020) |
"Menopause is an endocrine-related transition that induces a number of physiological and potentially pathological changes in middle-aged and elderly women." | ( Cui, X; Fan, Z; Gao, X; Hu, T; Likhodii, S; Randell, E; Sun, G; Yu, X; Zhang, J; Zhang, W, 2019) |
"Menopause is clinically diagnosed as a condition when a woman has not menstruated for one year." | ( Kim, HS; Ko, SH, 2020) |
"The age at menopause is not associated with the presence of MS." | ( Goulis, DG; Karageorgiou, V; Lambrinoudaki, I, 2020) |
"Menarche and menopause are two major components of a woman's reproductive life." | ( Mondal, N; Sen, J; Sinha, I; Tigga, P, 2021) |
"Menopause is the termination of menstruation and fertility." | ( Baser, M; Gürler, M; Kızılırmak, A, 2020) |
"Menopause is associated with bothersome symptoms for many women, including mood changes, hot flushes, sleep problems, and fatigue." | ( Cordeiro Mitchell, CN; Dolitsky, SN; Segars, JH; Stadler, SS, 2020) |
"The diagnosis of menopause is sometimes difficult." | ( Rousset-Jablonski, C, 2021) |
"Estrogen loss at menopause is thought to contribute to specific memory problems commonly encountered by women who are transitioning through or who have experienced menopause." | ( Korol, DL; Prakapenka, AV, 2021) |
"Menopause is a universal experience for midlife women." | ( Stuenkel, CA, 2021) |
"Menopause is a matter of concern for women's health due to a deficiency of female hormones; additionally, reactive oxygen species and aging can cause osteoporosis." | ( Chung, SI; Kang, MY; Ryu, SN, 2021) |
"However, menopause is a factor leading to deterioration of female vascular integrity, and it is reported that the risk of vascular diseases such as atherosclerosis and abdominal aortic aneurysm is increased in postmenopausal women." | ( Kiriyama, K; Kugo, H; Miyamoto, K; Moriyama, T; Nakamura, T; Sutoh, K; Zaima, N, 2021) |
"Menopause is associated with an overall increase in fat mass, which tends to accumulate around the waist." | ( Belda-Montesinos, R; Cano, A; Chedraui, P; Moccia, P; Monllor-Tormos, A, 2022) |
"If menopause is really independent risk factor for cardiovascular disease is still under debate." | ( Bartuskova, H; Hlinka, T; Huttl, M; Malinska, H; Markova, I; Miklankova, D; Pitha, J, 2022) |
"We found that menopause is a manifestation of the general aging process, with specific metabolic changes that aggravate menopausal symptoms, which are accelerated by estrogen depletion and associated neurotransmitter dysregulation." | ( Boonen, G; Culmsee, C; Drewe, J, 2022) |
"Menopause is a critical period of the woman life, characterized by a peculiar modification in estrogens concentration and accompanied by different signs and symptoms." | ( Giannetta, E; Pandozzi, C; Tarsitano, MG, 2022) |
"Early menopause is associated with a reduced risk of breast cancer, but increased risks of premature osteoporosis, cardiovascular disease and premature death." | ( Baber, RJ; Davis, SR, 2022) |
"The beginning of menopause is an ideal time for each woman to evaluate her health status by assessing her bone, cardiovascular, and cancer-related risk factors that may be amplified by postmenopausal estrogen deficiency and by reviewing her lifestyle habits." | ( André, G; Boutet, G; Chabbert-Buffet, N; Duclos, M; Fritel, X; Gosset, A; Graesslin, O; Hamdaoui, N; Hocke, C; Hugon-Rodin, J; Lecerf, JM; Lopes, P; Maitrot-Mantelet, L; Maris, E; Mathelin, C; Plu-Bureau, G; Pouilles, JM; Robin, G; Rousset-Jablonski, C; Trémollieres, FA, 2022) |
"Female menopause is a hormone deficiency phenomenon that causes hot flashes, vaginal dryness, depression, nervous tension, insomnia, obesity, and bone loss." | ( Choi, BR; Ha, IH; Hong, EY; Lee, YJ; Park, DR; Yeo, CH; Yoon, JE, 2022) |
"Menopause is a stage in life when a woman stops having menstruation and the ovaries produce less estrogen." | ( Abdul-Razzak, KK; Alkhatatbeh, MJ; Sindiani, AM, 2022) |
"Menopause is a physiological change in any woman." | ( Ali, M; Bączkowska, M; Byrczak, M; Ciebiera, M; Feduniw, S; Górski, K; Kociuba, J; Korczyńska, L; Zgliczyńska, M, 2022) |
"Menopause is a hormone-deficiency state that causes facial flushing, vaginal dryness, depression, anxiety, insomnia, obesity, osteoporosis, and cardiovascular disease as ovarian function decreases." | ( Choi, B; Ha, IH; Lee, YJ; Park, D; Yoon, JE, 2023) |
"Common symptoms of menopause are vasomotor (i." | ( Chang, JG; Lewis, MN; Wertz, MC, 2023) |