Lathyrism

A paralytic condition of the legs caused by ingestion of lathyrogens, especially BETA-AMINOPROPIONITRILE or beta-N-oxalyl amino-L-alanine, which are found in the seeds of plants of the genus LATHYRUS.

Synonym
Neurolathyrism
Lathyrism

Excerpt	Reference
"Osteolathyrism is ascribed to an inhibition of crosslinking of the collagen by the lathyrogen and should be accompanied by a decrease in the elastic modulus of the bone."	( Barnard, SM; Churchill, D; Lees, S, 1987)
"Lathyrism is a toxic disease of the motor system constantly associated with primary consumption of the seed of Lathyrus sativus (chickling or grass pea)."	( Dwivedi, MP; Hugon, J; Ludolph, AC; Schaumburg, HH; Spencer, PS, 1987)
"In Xenopus, osteolathyrism is expressed morphologically as anomalies in bone development, skeletal conformation, and abnormal connective tissue organization in the aorta wall."	( Dumont, JN; Newman, SM, 1983)
"Neurolathyrism is a form of spastic paraparesis caused by the neuroexcitatory amino acid 3-N-oxalyl-L-2,3-diaminopropanoic acid (beta-ODAP) present in the seeds and foliage of Lathyrus sativus."	( De Reuck, J; Haque, A; Hossain, M; Khan, JK; Kuo, YH; Lambein, F, 1994)
"Neurolathyrism is a neurological condition seen among people who eat the seeds of Lathyrus sativus (LS) as a principal source of food energy for 2 months or more."	( Ahmad, K; Jahan, K, 1993)
"Lathyrism is characterized by defective collagen synthesis due to inhibition of lysyl oxidase, an enzyme essential for interfibrillar cross-linking."	( Acikgoz, G; Kaymaz, FF; Keles, GC; Senturk, N; Turanli, AY; Yildiz, L, 2004)
"Konzo and lathyrism are associated with consumption of cassava and grass pea, respectively."	( Ambrosio, S; Boadas-Vaello, P; Cutillas, B; Llorens, J; Saldaña-Ruíz, S; Soler-Martín, C, 2011)
"Lathyrism is characterized by defective collagen synthesis due to inhibition of lysyl oxidase, an enzyme that is essential for interfibrillar collagen cross-linking."	( Acikgoz, G; Cengiz, MI; Kirtiloğlu, T; Trisi, P; Wang, HL, 2012)
"Neurolathyrism is a motor neuron disease caused by the overconsumption of grass pea (Lathyrus sativus L."	( Ikegami, F; Kusama, T; Kusama-Eguchi, K; Lambein, F; Minoura, A; Watanabe, K; Yoshino, N, 2011)
"Neurolathyrism is associated with a complex pattern of alterations in the glutamatergic system of the cortical motor region of brain."	( Ankulu, M; Aparna, N; Khandare, AL, 2013)
"Neurolathyrism is past history in India since Lathyrus sativus (khesari dal) is no longer used as a staple."	( Rao, SL; Singh, SS, 2013)
"Lathyrism is now rarely seen as a clinical disease in general, medical or neurology outpatient departments, throughout the world."	( Ansari, AZ; Chaurasia, RN; Joshi, D; Kumar, A; Kumar, B; Mishra, VN; Nandmer, V; Tripathi, CB, 2014)
"Neurolathyrism is a motor neuron (MN) disease caused by β-N-oxalyl-L-α,β-diaminopropionic acid (L-β-ODAP), an AMPA receptor agonist."	( Ikegami, F; Ishige, K; Ishii, M; Ito, Y; Kusama, T; Kusama-Eguchi, K; Miyano, T; Ogawa, Y; Suda, A; Watanabe, K; Yamamoto, M, 2014)
"Neurolathyrism is a non progressive motor neuron disorder engendered by the prolonged over-consumption of Lathyrus sativus (grass pea) seeds which contain a neurotoxic amino acid, β-N oxalyl- L-α, β-diaminopropionic acid (β-ODAP)."	( Ankulu, M; Aparna, N; Babu, JJ; Khandare, AL; Rao, GS; Shirfule, A, 2014)
"Neurolathyrism is a unique neurodegeneration disease caused by β-N-oxalyl-L-α, β- diaminopropionic (β-ODAP) present in grass pea seed (Lathyrus stativus L."	( Hu, WT; Kong, HY; Lambein, F; Li, FM; Li, ZX; Tan, RY; Xing, GY; Xiong, JL; Xiong, YC; Zhang, SX; Zhou, GM; Zhu, H, 2017)
"Lathyrism is a disease caused by excessive consumption of grass pea, Lathyrus sativus especially under conditions of severe drought."	( Arlappa, N; Khandare, AL; Kumar, RH; Laxmaiah, A; Meshram, II; Rao, PA; Toteja, GS; Validandi, V; Venkaiah, K, 2018)
"Neurolathyrism is a motor neuron disease that is caused by the overconsumption of grass peas (Lathyrus sativus L."	( Kumai, T; Kusama-Eguchi, K; Lambein, F; Minagawa, K; Suzuki, A; Ta, S; Yamada, SI, 2019)

Excerpt	Reference
"Lathyrism has been reviewed in respect to four overlapping phases: finding an animal model for neurolathyrism, characterizing osteolathyrism in respect to its possible use as an animal model for human diseases, such as Marfan's syndrome, idiopathic juvenile scoliosis, etc."	( Arunatut, O; Buranarugsa, MW; Yeager, VL, 1985)
"A primate model of lathyrism has been produced in well-nourished male cynomolgus monkeys chronically fed a fortified diet composed of Lathyrus sativus (chickling or grass pea) and given daily per os an alcoholic extract of this legume."	( Hugon, J; Ludolph, A; Roy, DN; Schaumburg, HH; Spencer, PS, 1988)

Excerpt	Reference
"It is not clear how lathyrism affects the systemic bone metabolism."	( Acikgoz, G; Basoglu, T; Cetinkaya, BO; Firatli, E; Keles, G; Yapici, O, 2006)

Excerpt	Reference
"This data supports the hypothesis that lathyrism and colchicine therapy exert a measurable beneficial effect on surface scar in human beings."	( Peacock, EE, 1981)
"As experimental model we used lathyrism induced in mice by chronic administration of beta-amino-propionitril (beta-APN)."	( Azzi, G; Robert, AM; Safars, M; Viljanen-Tarifa, E; Vörös, E, 1995)
"Experimental lathyrism was induced by once daily subcutaneous administration of beta-aminoproprionitrile (beta-APN), at a dose of 5 mg/0."	( Acikgoz, G; Ayas, B; Firatli, E; Keles, GG; Sakallioglu, E, 2005)
"Experimental lathyrism was induced by once daily subcutaneous administration of beta-aminopropionitrile (beta-APN), at a dose of 5 mg beta-APN/0."	( Acikgoz, G; Basoglu, T; Cetinkaya, BO; Firatli, E; Keles, G; Yapici, O, 2006)
"In the experimental group, lathyrism was induced by a once daily subcutaneous administration of beta-APN at a dose of 5mg in 0."	( Bashir, MH; El Rouby, DH; Korany, NS, 2008)
"In the experimental group (18 rats), lathyrism was induced by a once daily subcutaneous administration of beta-APN for 40 days."	( Bashir, MH; El Rouby, DH; Korany, NS, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	557 (87.99)	23.3326
1990's	26 (4.11)	12.5806
2000's	22 (3.48)	18.1394
2010's	28 (4.42)	28.8240
2020's	0 (0.00)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	low	1	0
acetaldehyde	low	1	0
acetone	low	1	0
ammonium hydroxide	low	2	0
beta-alanine	low	14	0
bromide	low	3	0
carbamates	low	6	0
choline	low	1	0
chlorine	low	2	0
hydrochloric acid	low	1	0
salicylic acid	low	1	0
2,3-diaminopropionic acid	low	2	0
aminocaproic acid	low	2	0
creatine	low	2	0
dimethyl sulfoxide	low	1	0
formaldehyde	low	5	0
glycine	low	5	0
glyceraldehyde	low	1	0
hydrogen cyanide	low	2	0
hydrogen carbonate	low	1	0
histamine	low	2	0
niacin	low	7	0
pyridoxal	low	3	0
pyridoxal phosphate	low	1	0
pyridoxine	low	6	0
thiosulfates	low	2	0
sulfites	low	1	0
taurine	low	1	0
thiamine	low	3	0
urea	low	9	0
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	low	1	0
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	low	1	0
2,4-dinitrophenol	low	2	0
mercaptoethanol	low	1	0
aminopropionitrile	medium	241	2
3-methylcholanthrene	low	1	0
phenytoin	low	1	0
aspirin	low	1	0
chloroquine	low	4	0
clioquinol	low	1	0
erythrosine	low	2	0
guanidine	low	1	0
hydralazine	low	1	0
iproniazid	low	2	0
isoniazid	low	10	0
khellin	low	1	0
mephenesin	low	1	0
metformin	low	1	0
ethylmaleimide	low	1	0
neostigmine	low	2	0
pargyline	low	1	0
phenobarbital	low	1	0
phenylbutazone	low	3	0
procaine	low	2	0
pyridinolcarbamate	low	7	0
carbamylhydrazine	low	8	0
tolperisone	medium	1	1
trientine	low	1	0
corticosterone	low	1	0
prednisolone	low	4	0
lysergic acid diethylamide	low	1	0
thymidine	low	3	0
hydroxyproline	low	45	0
thyroxine	low	7	0
penicillamine	low	38	0
prednisone	low	2	0
triiodothyronine	low	2	0
alanine	low	13	0
serine	low	1	0
aspartic acid	low	2	0
glutamine	low	5	0
lysine	low	25	0
cyanides	low	127	0
sucrose	low	1	0
9,10-dimethyl-1,2-benzanthracene	low	1	0
galactose	low	6	0
edetic acid	low	3	0
tyrosine	low	1	0
cysteamine	low	2	0
leucine	low	4	0
methionine	low	8	0
phenylalanine	low	1	0
desoxycorticosterone	low	1	0
colchicine	low	3	0
cycloserine	low	1	0
asparagine	low	1	0
histidine	low	2	0
valine	low	1	0
alizarin	low	1	0
isoleucine	low	1	0
arginine	low	1	0
acetone cyanohydrin	low	1	0
pantothenic acid	low	2	0
quinoxalines	low	1	0
furaldehyde	low	1	0
phenylhydrazine	low	1	0
allylamine	low	1	0
propionitrile	low	5	0
2-methylpentane	low	1	0
allyl cyanide	low	1	0
3,3'-iminodipropionitrile	low	3	0
ergotamine	low	1	0
ditiocarb	low	1	0
catechin	low	1	0
homoarginine	low	3	0
isoxazoles	low	2	0
thiazoles	low	3	0
hydrazine	low	11	0
methysergide	low	2	0
cyanoacetic acid	low	1	0
nandrolone	low	1	0
cyanogen	low	1	0
cyanogen bromide	low	7	0
aminoacetonitrile	low	30	0
hematoporphyrin	low	2	0
acetylcysteine	low	1	0
3-cyanoalanine	low	2	0
oxalic acid hydrazide	low	1	0
sodium hydroxide	low	2	0
d-alpha tocopherol	low	4	0
uridine diphosphate galactose	low	1	0
dithiothreitol	low	2	0
manganese	low	5	0
mercury	low	2	0
technetium	low	1	0
cadmium	low	1	0
gold	low	2	0
galactosamine	low	1	0
bromine	low	3	0
zinc sulfate	low	1	0
copper sulfate	low	2	0
deuterium	low	1	0
nitrous acid	low	1	0
galactose	low	5	0
trolamine salicylate	low	5	0
ammonium chloride	low	1	0
fluorides	low	1	0
phenyl acetate	low	8	0
alkenes	low	1	0
glutamic acid	low	1	0
azides	low	3	0
metsulfuron methyl	low	1	0
metaperiodate	low	2	0
glutaurine	low	1	0
coenzyme a	low	1	0
homocysteine	low	1	0
p-methoxy-n-methylphenethylamine	low	1	0
vitamin b 6	low	1	0
cyanates	low	1	0
pyridinoline	low	2	0
beta-n-methylamino-l-alanine	low	1	0
procyanidin	low	1	0
alpha-n-carboxy-beta-n-methylaminoalanine	low	1	0
xylose	low	1	0
proline	medium	22	1
serine o-sulfate	low	1	0
organophosphonates	low	1	0
cortisone	low	4	0
solanine	low	1	0
glycogen	low	3	0
fibrin	low	1	0
canavanine	low	1	0
glucosamine	low	7	0
elastin	low	49	0
puromycin	low	2	0
retinol	low	8	0
dactinomycin	low	1	0
azaserine	low	1	0
riboflavin	low	1	0
bromochloroacetic acid	low	1	0
glycosides	low	6	0
crotononitrile	low	1	0
pyrophosphate	low	1	0
propylthiouracil	low	1	0
thiouracil	low	2	0
thiosemicarbazide	low	4	0
nitrogen dioxide	low	1	0
dermatan sulfate	low	1	0
hydroxylysine	low	8	0
quinine	low	1	0
cystine	low	3	0
ovalbumin	low	1	0
6-cyano-7-nitroquinoxaline-2,3-dione	low	1	0
alpha-chymotrypsin	low	2	0
vitamin k semiquinone radical	low	2	0
hymecromone	low	1	0
vitamin d 2	low	1	0
lysophosphatidylcholines	low	1	0
strontium	low	1	0
sulfur	low	2	0
fumarates	low	16	0
cysteine	low	8	0
phosphorus	low	2	0
strontium radioisotopes	low	1	0
selenium	low	4	0
oxalates	low	7	0
beta-aminopropionitrile fumarate	low	9	0
beta-escin	low	1	0
sepharose	low	1	0
acid phosphatase	low	6	0
jaw	low	1	0
desmosine	low	1	0
glucagon	low	2	0
cellulose	low	2	0
phosphatidylcholines	low	1	0
sodium salicylate	low	6	0
nuclear fast red	low	1	0
sodium ethylxanthate	low	1	0
glycolipids	low	1	0
methylcellulose	low	3	0
chondroitin	low	8	0
heparitin sulfate	low	4	0
ascorbic acid	low	8	0
tetracycline	low	4	0
salicylates	low	2	0
demeclocycline	low	1	0
transforming growth factor beta	low	1	0
lysine tyrosylquinone	low	1	0
glutaminase	low	1	0
caseins	low	2	0
hyaluronoglucosaminidase	low	2	0
vitamin b 12	low	3	0
chondroitin sulfates	low	2	0
phosphorus radioisotopes	low	2	0

Protein Targets (1,082)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Dihydropteridine reductase	0	1	0	1
Amine oxidase [flavin-containing] A	0	4	0	5
Amine oxidase [flavin-containing] B	0	7	1	8
Amine oxidase [flavin-containing] B	0	1	0	2
retinoic acid nuclear receptor alpha variant 1	41	0	0	41
retinoid X nuclear receptor alpha	29	0	0	29
estrogen-related nuclear receptor alpha	43	0	0	43
pregnane X nuclear receptor	35	0	0	35
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
acetylcholinesterase	16	0	0	16
pregnane X receptor	11	0	0	11
RAR-related orphan receptor gamma	32	0	0	32
TDP1 protein	32	0	0	32
GLI family zinc finger 3	37	0	0	37
AR protein	51	0	0	51
aldehyde dehydrogenase 1 family, member A1	36	0	0	36
thyroid stimulating hormone receptor	16	0	0	16
estrogen receptor 2 (ER beta)	19	0	0	19
nuclear receptor subfamily 1, group I, member 3	32	0	0	32
glucocorticoid receptor [Homo sapiens]	33	0	0	33
estrogen nuclear receptor alpha	57	0	0	57
67.9K protein	4	0	0	4
peroxisome proliferator-activated receptor delta	23	0	0	23
peroxisome proliferator activated receptor gamma	22	0	0	22
vitamin D (1,25- dihydroxyvitamin D3) receptor	28	0	0	28
aryl hydrocarbon receptor	21	0	0	21
cellular tumor antigen p53 isoform a	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	13	0	0	13
thyroid hormone receptor beta isoform a	17	0	0	17
nuclear factor erythroid 2-related factor 2 isoform 2	9	0	0	10
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
thyroid hormone receptor beta isoform 2	29	0	0	29
histone deacetylase 9 isoform 3	2	0	0	2
mitogen-activated protein kinase 1	12	0	0	12
nuclear factor erythroid 2-related factor 2 isoform 1	37	0	0	37
nuclear receptor ROR-gamma isoform 1	13	0	0	13
geminin	30	0	0	30
survival motor neuron protein isoform d	15	0	0	15
histone acetyltransferase KAT2A isoform 1	18	0	0	18
Voltage-dependent calcium channel gamma-2 subunit	15	0	0	15
Cellular tumor antigen p53	24	0	0	24
Integrin beta-3	3	2	1	6
Integrin alpha-IIb	3	2	1	6
Glutamate receptor 2	16	4	2	22
Nuclear receptor ROR-gamma	12	0	0	12
TAR DNA-binding protein 43	6	0	0	6
ATPase family AAA domain-containing protein 5	9	0	0	9
Ataxin-2	12	0	0	12
Luciferase	14	0	0	14
phosphopantetheinyl transferase	20	0	0	20
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
Microtubule-associated protein tau	15	0	0	15
caspase 7, apoptosis-related cysteine protease	5	0	0	5
farnesoid X nuclear receptor	18	0	0	18
caspase-3	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	52	0	0	52
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
activating transcription factor 6	14	0	0	14
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
heat shock protein beta-1	15	0	0	15
Cytochrome P450 1A2	0	5	0	5
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	2	1	3
Aldo-keto reductase family 1 member B1	0	5	0	5
Adenosine receptor A3	0	2	0	2
Alpha-1B adrenergic receptor	0	3	1	4
Acetylcholinesterase	0	6	0	6
Sodium-dependent noradrenaline transporter	0	2	0	2
Aryl hydrocarbon receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	3	1	4
15-lipoxygenase, partial	11	0	0	11
USP1 protein, partial	17	0	0	17
glucocerebrosidase	8	0	0	8
lethal factor (plasmid)	12	0	0	12
Glutamate receptor 1	0	5	2	7
Glutamate receptor 2	0	5	2	7
Glutamate receptor 3	0	4	1	5
Glutamate receptor 4	0	5	1	6
Inositol monophosphatase 1	4	0	0	4
Chain A, Beta-lactamase	8	0	0	8
Chain A, HADH2 protein	15	0	0	15
Chain B, HADH2 protein	15	0	0	15
Chain A, Cruzipain	6	0	0	6
acid sphingomyelinase	1	0	0	1
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
ATAD5 protein, partial	10	0	0	10
apical membrane antigen 1, AMA1	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
progesterone receptor	19	0	0	19
bromodomain adjacent to zinc finger domain 2B	7	0	0	7
P53	1	0	0	1
IDH1	10	0	0	10
thyroid stimulating hormone receptor	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	20	0	0	20
Caspase-7	6	0	0	6
serine-protein kinase ATM isoform a	1	0	0	1
chromobox protein homolog 1	25	0	0	25
caspase-3	6	0	0	6
nuclear factor NF-kappa-B p105 subunit isoform 1	3	0	0	3
ras-related protein Rab-9A	3	0	0	3
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
cytochrome P450 3A4 isoform 1	18	0	0	18
caspase-1 isoform alpha precursor	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	18	1	1	20
Gamma-aminobutyric acid receptor subunit beta-1	18	1	1	20
Gamma-aminobutyric acid receptor subunit delta	18	1	1	20
Gamma-aminobutyric acid receptor subunit gamma-2	18	1	1	20
Gamma-aminobutyric acid receptor subunit alpha-5	18	1	1	20
Gamma-aminobutyric acid receptor subunit alpha-3	18	1	1	20
Gamma-aminobutyric acid receptor subunit gamma-1	18	1	1	20
Gamma-aminobutyric acid receptor subunit alpha-2	18	1	1	20
Gamma-aminobutyric acid receptor subunit alpha-4	18	1	1	20
Gamma-aminobutyric acid receptor subunit gamma-3	18	1	1	20
Gamma-aminobutyric acid receptor subunit alpha-6	18	1	1	20
Caspase-7	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	18	2	1	21
Gamma-aminobutyric acid receptor subunit beta-3	18	1	1	20
Gamma-aminobutyric acid receptor subunit beta-2	18	1	1	20
GABA theta subunit	18	1	1	20
Gamma-aminobutyric acid receptor subunit epsilon	18	1	1	20
thyrotropin-releasing hormone receptor	4	0	0	4
Histone H2A.x	17	0	0	17
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Fibrinogen C domain-containing protein 1	0	1	0	1
lamin isoform A-delta10	27	0	0	27
Chain A, 2-oxoglutarate Oxygenase	17	0	0	17
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
dopamine D1 receptor	4	0	0	4
NFKB1 protein, partial	4	0	0	4
Thrombopoietin	7	0	0	7
regulator of G-protein signaling 4	17	0	0	17
arylsulfatase A	15	0	0	15
Bloom syndrome protein isoform 1	13	0	0	13
D(1A) dopamine receptor	4	0	0	4
flap endonuclease 1	15	0	0	15
peripheral myelin protein 22	15	0	0	15
muscarinic acetylcholine receptor M1	15	0	0	15
Histone deacetylase 3	0	2	0	2
Solute carrier family 22 member 6	0	3	0	3
Histone deacetylase 4	0	2	0	2
Guanine nucleotide-binding protein G	2	0	0	2
Histone deacetylase 1	0	2	0	2
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
ATP-dependent phosphofructokinase	18	0	0	18
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	24	0	0	24
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
Carbonic anhydrase 1	0	21	0	32
Carbonic anhydrase 2	0	22	1	35
Alanine racemase, biosynthetic	0	0	0	1
5-hydroxytryptamine receptor 1D	0	2	0	6
Glutamate receptor ionotropic, NMDA 1	0	11	3	18
Proton-coupled amino acid transporter 1	0	12	0	13
Adenosine deaminase	0	0	0	1
Carbonic anhydrase 4	0	0	0	4
endonuclease IV	5	0	0	5
WRN	1	0	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	27	0	0	27
G	13	0	0	13
cytochrome P450 2D6	12	0	0	12
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
importin subunit beta-1 isoform 1	5	0	0	5
serine/threonine-protein kinase PLK1	2	0	0	2
snurportin-1	5	0	0	5
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
tumor susceptibility gene 101 protein	1	0	0	1
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	10	0	0	10
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
DNA polymerase kappa isoform 1	12	0	0	12
Vpr	1	0	0	1
kelch-like ECH-associated protein 1	0	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Interferon beta	20	0	0	20
HLA class I histocompatibility antigen, B alpha chain	13	0	0	13
Transthyretin	0	3	0	5
Gag-Pol polyprotein	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Glutamate receptor 1	1	4	2	7
Glutamate receptor 3	1	4	2	7
Glutamate receptor 4	1	4	2	7
Histamine H2 receptor	7	0	1	9
Induced myeloid leukemia cell differentiation protein Mcl-1	0	3	0	3
Cytochrome P450 1B1	0	2	0	2
RmtA	0	1	0	1
Reverse transcriptase/RNaseH	0	2	0	3
Inositol hexakisphosphate kinase 1	13	0	0	13
Protein arginine N-methyltransferase 1	0	1	0	1
cytochrome P450 2C9, partial	13	0	0	13
phosphoglycerate kinase	1	0	0	1
Amine oxidase [flavin-containing] B	0	4	0	4
Amine oxidase [flavin-containing] A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutamate receptor ionotropic, kainate 1	0	4	1	5
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	3	1	4
Glutamate receptor ionotropic, kainate 2	0	4	1	5
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Excitatory amino acid transporter 1	0	5	0	6
Excitatory amino acid transporter 2	0	4	0	5
Excitatory amino acid transporter 3	0	5	0	6
Glutamate receptor ionotropic, NMDA 2A	0	9	3	16
Glutamate receptor ionotropic, NMDA 2B	0	9	3	16
Glutamate receptor ionotropic, NMDA 2C	0	9	3	16
Glutamate receptor ionotropic, kainate 4	0	3	0	3
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, kainate 2	0	3	1	4
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	9	3	16
Glutamate receptor ionotropic, kainate 5	0	3	0	3
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	9	3	16
Glutamate receptor ionotropic, NMDA 3A	0	9	3	16
Glutamate receptor 4	0	1	0	1
Glutamate receptor 3	0	1	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, Ferritin light chain	7	0	0	7
Chain A, Apolipoprotein	0	0	1	1
EWS/FLI fusion protein	12	0	0	12
nonstructural protein 1	5	0	0	5
Rap guanine nucleotide exchange factor 3	7	0	0	7
Plasminogen	0	2	1	3
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	3	3
thioredoxin reductase	28	0	0	28
GLS protein	20	0	0	20
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	6	0	0	6
Cytochrome P450 3A4	0	9	0	10
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	1	1	4
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	8	0	0	8
Polyphenol oxidase 2	0	9	0	12
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	7	1	8
Spike glycoprotein	4	1	1	6
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Neutral amino acid transporter A	0	5	0	5
Neutral amino acid transporter B(0)	0	5	0	5
Carbonic anhydrase-like protein, putative	0	0	0	8
Amino acid transporter	0	5	0	5
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	5	0	0	5
hypothetical protein, conserved	2	0	0	2
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
ATP-binding cassette sub-family C member 3	0	16	0	16
Multidrug resistance-associated protein 4	0	16	0	16
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Bile salt export pump	0	34	0	34
Epidermal growth factor receptor	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	2	1	3
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	0	2	0	6
Adenosine receptor A2a	0	2	0	6
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	7	0	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Canalicular multispecific organic anion transporter 1	0	16	0	16
Sigma non-opioid intracellular receptor 1	0	4	1	5
Sigma non-opioid intracellular receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	8	0	11
5-hydroxytryptamine receptor 4	0	6	0	6
Muscarinic acetylcholine receptor M2	0	4	1	8
Muscarinic acetylcholine receptor M4	0	3	1	6
Muscarinic acetylcholine receptor M1	0	2	1	5
Muscarinic acetylcholine receptor M3	0	2	1	5
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M5	0	3	1	6
Muscarinic acetylcholine receptor M2	0	2	1	6
Muscarinic acetylcholine receptor M1	0	3	1	7
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	3	1	6
Alpha-1D adrenergic receptor	0	4	0	4
5-hydroxytryptamine receptor 2C	0	7	0	7
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 7	0	3	0	3
Muscarinic acetylcholine receptor	0	1	1	2
vitamin D3 receptor isoform VDRA	15	0	0	15
Carbonic anhydrase 4	0	14	0	19
Carbonic anhydrase	0	10	0	14
Carbonic anhydrase 15	0	10	0	14
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
peripheral myelin protein 22 isoform 1	5	0	0	5
neuropeptide S receptor isoform A	6	0	0	6
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	3	4
Carbonic anhydrase 6	0	7	0	12
Sucrase-isomaltase, intestinal	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Xanthine dehydrogenase/oxidase	0	3	0	3
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
PPM1D protein	4	0	0	4
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	1	2
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	5	0	5
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	1	1	2
Alpha-2A adrenergic receptor	0	6	0	6
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Spike glycoprotein	0	2	0	2
Replicase polyprotein 1ab	0	1	1	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2C adrenergic receptor	0	4	0	4
DNA ligase 1	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	1	2
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	3	0	6
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	9	0	14
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	10	0	13
glp-1 receptor, partial	5	0	0	5
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
Fumarate hydratase	4	0	0	4
Smad3	3	0	0	3
polyprotein	4	0	0	4
LAP4	0	0	1	1
MEP2	0	0	1	1
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
huntingtin isoform 2	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
heat shock protein HSP 90-alpha isoform 2	0	2	0	3
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Carbonic anhydrase 12	0	3	0	8
Carbonic anhydrase 3	0	2	0	7
Botulinum neurotoxin type A	0	1	0	1
Catechol O-methyltransferase	0	2	0	2
Alpha-1D adrenergic receptor	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	6	0	11
Alpha-synuclein	1	2	0	3
Carbonic anhydrase 7	0	5	0	10
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Carbonic anhydrase 9	0	7	1	13
Beta-galactosidase	0	0	1	1
Carbonic anhydrase 13	0	5	0	9
Carbonic anhydrase 14	0	2	0	7
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
N-alpha-acetyltransferase 50	0	0	1	1
PAX8	0	0	0	1
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
cytochrome P450 2D6 isoform 1	5	0	0	5
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C9 precursor	5	0	0	5
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	5	0	0	5
Solute carrier family 22 member 3	0	5	0	6
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	5
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	2	0	2
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	4	0	7
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
GALC protein	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Solute carrier family 22 member 3	0	2	0	2
Sex hormone-binding globulin	0	0	4	4
Corticosteroid-binding globulin	0	5	0	5
Mineralocorticoid receptor	0	2	2	4
Androgen receptor	0	6	0	6
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
M-phase phosphoprotein 8	5	0	0	5
Glucocorticoid receptor	0	8	2	15
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Bile salt export pump	0	8	0	8
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
RAD51	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	2	0	2
Discoidin domain-containing receptor 2	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	2	0	2
Gasdermin-D	0	1	0	1
Gasdermin-D	0	1	0	1
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Adenylate cyclase	0	1	0	1
Beta-2 adrenergic receptor	0	3	0	3
Beta-1 adrenergic receptor	0	3	0	3
D(2) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	6	0	6
D(1A) dopamine receptor	0	4	0	4
Sodium-dependent dopamine transporter	0	2	0	2
Thromboxane-A synthase	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	1	6
5-hydroxytryptamine receptor 1B	0	4	0	4
D(3) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2B	0	5	0	5
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 6	0	5	0	5
Genome polyprotein	0	2	1	3
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
eyes absent homolog 2 isoform a	2	0	0	2
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
Ghrelin O-acyltransferase	0	1	0	1
Monoglyceride lipase	0	1	0	1
14 kDa phosphohistidine phosphatase	0	1	0	1
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Metabotropic glutamate receptor 5	0	1	1	3
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate carboxypeptidase 2	0	2	0	2
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Asc-type amino acid transporter 1	0	2	0	2
Aldo-keto reductase family 1 member B10	0	0	0	2
Aldo-keto reductase family 1 member B1	0	3	0	5
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	8	0	9
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	3	0	3
Histamine H2 receptor	0	1	2	3
Histamine H1 receptor	0	1	3	4
Histamine H1 receptor	0	2	1	3
Histamine H1 receptor	0	3	2	5
Carbonic anhydrase	0	0	0	5
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	3	0	8
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	0	0	5
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Carbonic anhydrase 5B, mitochondrial	0	5	0	9
Histamine H3 receptor	0	1	2	3
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Parkin	2	0	0	2
pyruvate kinase	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase, alpha family	0	1	0	1
Glutamine synthetase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Acetylcholinesterase	0	3	0	3
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	2	0	2
Genome polyprotein	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Cholinesterase	0	3	0	3
Sorbitol dehydrogenase	0	1	0	1
Oleandomycin glycosyltransferase	0	0	0	1
Cytochrome P450 2D6	0	5	0	5
C-X-C chemokine receptor type 3	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 2C19	0	3	0	3
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Chymotrypsinogen A	0	2	0	2
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 2C9	0	7	1	8
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	1	2
D(4) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
D	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
DNA polymerase III, partial	1	0	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Cholinesterase	0	2	0	2
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Pyrroline-5-carboxylate reductase 1, mitochondrial	0	1	0	1
Renin	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	0	1	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	2
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Histone acetyltransferase KAT8	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Androgen receptor	0	3	0	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	1	0	1
Estrogen receptor beta	0	2	0	2
Glutamate 5-kinase	0	0	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	2	4
30S ribosomal protein S6	0	2	0	3
30S ribosomal protein S7	0	2	0	3
50S ribosomal protein L15	0	2	0	3
50S ribosomal protein L10	0	2	0	3
50S ribosomal protein L11	0	2	0	3
50S ribosomal protein L7/L12	0	2	0	3
50S ribosomal protein L19	0	2	0	3
50S ribosomal protein L1	0	2	0	3
50S ribosomal protein L20	0	2	0	3
50S ribosomal protein L27	0	2	0	3
50S ribosomal protein L28	0	2	0	3
50S ribosomal protein L29	0	2	0	3
50S ribosomal protein L31	0	2	0	3
50S ribosomal protein L31 type B	0	2	0	3
50S ribosomal protein L32	0	2	0	3
50S ribosomal protein L33	0	2	0	3
50S ribosomal protein L34	0	2	0	3
50S ribosomal protein L35	0	2	0	3
50S ribosomal protein L36	0	2	0	3
30S ribosomal protein S10	0	2	0	3
30S ribosomal protein S11	0	2	0	3
30S ribosomal protein S12	0	2	0	3
30S ribosomal protein S13	0	2	0	3
30S ribosomal protein S16	0	2	0	3
30S ribosomal protein S18	0	2	0	3
30S ribosomal protein S19	0	2	0	3
30S ribosomal protein S20	0	2	0	3
30S ribosomal protein S2	0	2	0	3
30S ribosomal protein S3	0	2	0	3
30S ribosomal protein S4	0	2	0	3
30S ribosomal protein S5	0	2	0	3
30S ribosomal protein S8	0	2	0	3
30S ribosomal protein S9	0	2	0	3
50S ribosomal protein L13	0	2	0	3
50S ribosomal protein L14	0	2	0	3
50S ribosomal protein L16	0	2	0	3
50S ribosomal protein L23	0	2	0	3
30S ribosomal protein S15	0	2	0	3
50S ribosomal protein L17	0	2	0	3
50S ribosomal protein L21	0	2	0	3
50S ribosomal protein L30	0	2	0	3
50S ribosomal protein L6	0	2	0	3
30S ribosomal protein S14	0	2	0	3
30S ribosomal protein S17	0	2	0	3
30S ribosomal protein S1	0	2	0	3
50S ribosomal protein L18	0	2	0	3
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
50S ribosomal protein L2	0	2	0	3
50S ribosomal protein L3	0	2	0	3
50S ribosomal protein L24	0	2	0	3
50S ribosomal protein L4	0	2	0	3
50S ribosomal protein L22	0	2	0	3
50S ribosomal protein L5	0	2	0	3
30S ribosomal protein S21	0	2	0	3
50S ribosomal protein L25	0	2	0	3
50S ribosomal protein L36 2	0	2	0	3
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Pyridoxal kinase	0	0	0	2
Aldehyde oxidase	0	1	0	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	1	0	1
P2X purinoceptor 4	0	0	1	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Potassium channel subfamily K member 2	0	1	0	1
Albumin	0	1	2	3
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
tumor necrosis factor	1	0	0	1
60 kDa chaperonin	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	2	0	2
Thiosulfate sulfurtransferase	0	2	0	2
60 kDa chaperonin	0	2	0	2
10 kDa chaperonin	0	2	0	2
Neuraminidase	0	2	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Pyruvate kinase PKM	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine kinase, cytosolic	0	2	0	4
Thymidine kinase	0	1	0	2
Thymidylate synthase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
Cannabinoid receptor 1	0	1	0	1
Diamine acetyltransferase 1	0	0	0	1
Thialysine N-epsilon-acetyltransferase	0	0	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	0	1	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Beta-1,4-galactosyltransferase 1	0	0	0	1
N-acetyllactosaminide alpha-1,3-galactosyltransferase	0	0	0	1
P2Y purinoceptor 14	0	0	1	1
Chain A, Arginase 1	0	1	0	1
Vitamin D3 receptor	0	0	0	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Hsf1 protein	0	0	1	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

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Studies (633)

Protein Targets (1,082)

Lathyrism

Synonyms(2)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (633)

Drugs Studied (263)

Protein Targets (1,082)