Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms.
| Member | Definition | Class |
|---|
| 2,2'-dipyridyl | A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'. | 2,2'-bipyridine |
| 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures. | Trolox |
| aa 861 | A member of the class of benzoquinones that is p-benzoquinone in which the hydrogens are substituted by three methyl groups and a 12-hydroxydodeca-5,10-diyn-1-yl group. | docebenone |
| acetylcysteine | An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine. | N-acetyl-L-cysteine |
| ammonium chloride | An inorganic chloride having ammonium as the counterion. | ammonium chloride |
| bafilomycin a1 | The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. | bafilomycin A1 |
| baicalein | A trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. | baicalein |
| baicalin | The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis. | baicalin |
| beta carotene | A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid. | beta-carotene |
| butylated hydroxytoluene | A member of the class of phenols that is 4-methylphenol substituted by tert-butyl groups at positions 2 and 6. | 2,6-di-tert-butyl-4-methylphenol |
| coenzyme q10 | A ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration. | coenzyme Q10 |
| cycloheximide | A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. | cycloheximide |
| deferoxamine | An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator. | desferrioxamine B |
| desferrioxamine b mesylate | A methanesulfonate salt obtained by reaction of desferrioxamine B with one molar equivalent of methanesulfonic acid. It is an iron-chelating medicine used to remove excess iron from the body. It binds to iron in the blood, which is then passed out in the urine. | desferrioxamine B mesylate |
| diphenylamine | An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union. | diphenylamine |
| ebselen | A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. | ebselen |
| ferrostatin-1 | An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals. | ferrostatin-1 |
| idebenone | A member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia. | idebenone |
| liproxstatin-1 | An azaspiro compound that is 1'H-spiro[piperidine-4,2'-quinoxaline] in which the hydrogen at position 3' is replaced by a (3-chlorobenzyl)amino group. It is a potent inhibitor of ferroptosis. | liproxstatin-1 |
| masoprocol | A tetrol that is butane which is substituted at positions 2 and 3 by 3,4-dihydroxybenzyl groups. Masoprocol, the meso-form found in the leaves of the creosote bush (Larrea divaricata), is a potent lipoxygenase inhibitor. | nordihydroguaiaretic acid |
| pd 146176 | An organic heterotetracyclic compound that is 1H-indole which is ortho-fused to a 2H-1-benzothiopyran group at positions 2-3. It is an inhibitor of 15-lipoxygenase that limits atherosclerotic lesion development in rabbits. | PD-146176 |
| phenothiazine | The 10H-tautomer of phenothiazine. | 10H-phenothiazine |
| phenoxazine | A member of the class of phenoxazines that is morpholine which is ortho-fused to two benzene rings at positions 2-3 and 5-6. | 10H-phenoxazine |
| pioglitazone | A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity. | pioglitazone |
| rosiglitazone | | rosiglitazone |
| tempo | A member of the class of aminoxyls that is piperidine that carries an oxidanediyl group at position 1 and methyl groups at positions 2, 2, 6, and 6, respectively. | TEMPO |
| tocotrienol, alpha | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a farnesyl chain at position 2. It has been found in palm oil derived from Elaeis guineensis. | alpha-tocotrienol |
| troglitazone | | troglitazone |
| zileuton | A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma. | zileuton |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 13.1363 | 1 | 10 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 2.6987 | 1 | 7 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 7.5686 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 11.1577 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 49.5930 | 3 | 7 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 34.6441 | 2 | 7 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 15.4778 | 1 | 15 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 32.4648 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 3.7547 | 1 | 4 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 9.9398 | 1 | 5 |
| AR protein | Homo sapiens (human) | Potency | 22.3447 | 11 | 78 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 24.0030 | 2 | 12 |
| arylsulfatase A | Homo sapiens (human) | Potency | 17.9304 | 1 | 3 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 13.7801 | 3 | 7 |
| Ataxin-2 | Homo sapiens (human) | Potency | 7.5244 | 2 | 6 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 12.6709 | 5 | 9 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 2.4865 | 2 | 6 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 6.7456 | 1 | 1 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 26.1216 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 5.2515 | 2 | 8 |
| BRCA1 | Homo sapiens (human) | Potency | 10.8820 | 1 | 2 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 36.6728 | 1 | 5 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 76.9588 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 76.9588 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 40.8834 | 3 | 18 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 8.8859 | 2 | 5 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 16.1273 | 1 | 17 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 28.2856 | 4 | 11 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 36.8266 | 2 | 4 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 26.6514 | 2 | 2 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 20.1277 | 2 | 5 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 8.2221 | 2 | 11 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.8162 | 1 | 7 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 15.2712 | 3 | 16 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 17.5942 | 3 | 15 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 17.1572 | 1 | 15 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 8.2221 | 2 | 11 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 36.2202 | 2 | 9 |
| ClpP | Bacillus subtilis | Potency | 31.6228 | 1 | 1 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 2.9336 | 1 | 4 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 2.7758 | 1 | 4 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 9.5340 | 1 | 5 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 14.3029 | 1 | 4 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 18.5614 | 1 | 4 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 16.1701 | 2 | 17 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.2117 | 2 | 9 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 33.7102 | 1 | 12 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 14.0958 | 2 | 2 |
| D(1A) dopamine receptor | Sus scrofa (pig) | Potency | 26.1216 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 38.3152 | 1 | 6 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 11.6909 | 2 | 4 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 4.7444 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 33.3292 | 2 | 8 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 5.2954 | 1 | 7 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 0.0206 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 9.5818 | 2 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 23.2360 | 11 | 71 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 23.1205 | 2 | 12 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 24.5532 | 9 | 65 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 14.5927 | 1 | 22 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 15.5841 | 4 | 16 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 36.8051 | 4 | 10 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 43.6950 | 1 | 7 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 22.3872 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 5.0468 | 1 | 2 |
| G | Vesicular stomatitis virus | Potency | 9.5340 | 1 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 16.1523 | 1 | 9 |
| geminin | Homo sapiens (human) | Potency | 9.6286 | 4 | 27 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.0071 | 3 | 18 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 7.4598 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 6.6718 | 2 | 9 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 35.5869 | 1 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 25.4052 | 5 | 19 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 8.6438 | 1 | 2 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 0.6310 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 14.9109 | 2 | 8 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 0.6310 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 0.6310 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 48.3019 | 2 | 3 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 43.6303 | 2 | 7 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 8.6438 | 1 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 3.5273 | 2 | 24 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 17.7480 | 1 | 10 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 58.2725 | 2 | 15 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 9.5340 | 1 | 5 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 18.9667 | 4 | 8 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 35.9959 | 2 | 5 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 11.2035 | 2 | 10 |
| IDH1 | Homo sapiens (human) | Potency | 11.0134 | 1 | 3 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 141.2540 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 9.5340 | 1 | 10 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 3.9811 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 9.1825 | 3 | 13 |
| interleukin 8 | Homo sapiens (human) | Potency | 74.9780 | 1 | 3 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 13.2689 | 1 | 13 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 4.3443 | 1 | 7 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 34.5592 | 4 | 15 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 18.0789 | 3 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 13.4574 | 1 | 3 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 19.3285 | 1 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 16.6069 | 2 | 24 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 37.0814 | 2 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 15.1861 | 1 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 12.9244 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 10.3938 | 2 | 6 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 2.1154 | 1 | 2 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 0.4467 | 1 | 1 |
| Nrf2 | Homo sapiens (human) | Potency | 29.2278 | 2 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 27.2837 | 4 | 26 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 7.8222 | 2 | 4 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 13.4670 | 1 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 37.8678 | 1 | 9 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 0.1934 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 14.1915 | 2 | 22 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 18.0575 | 3 | 28 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| P53 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 84.3495 | 1 | 6 |
| Parkin | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 51.6252 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 17.2864 | 2 | 9 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 54.7470 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 18.7458 | 5 | 23 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 18.7494 | 4 | 12 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 29.3239 | 1 | 13 |
| PINK1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.8422 | 1 | 5 |
| polyprotein | Zika virus | Potency | 5.0468 | 1 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 12.1591 | 1 | 6 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 4.2787 | 1 | 6 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 15.8014 | 1 | 6 |
| PPM1D protein | Homo sapiens (human) | Potency | 9.4095 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 37.1865 | 3 | 12 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 50.3175 | 1 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 24.3168 | 2 | 13 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.5513 | 5 | 5 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 5.1189 | 4 | 4 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 40.8708 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 16.7177 | 2 | 24 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 0.3162 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 15.3296 | 1 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 22.2294 | 3 | 27 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 10.8800 | 4 | 29 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 20.0061 | 3 | 4 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 19.3862 | 1 | 4 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Potency | 5.7988 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 18.3020 | 2 | 3 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 18.3020 | 2 | 3 |
| Smad3 | Homo sapiens (human) | Potency | 14.9316 | 1 | 4 |
| snurportin-1 | Homo sapiens (human) | Potency | 141.2540 | 1 | 1 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 22.2818 | 1 | 5 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 6.8894 | 1 | 10 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 6.5356 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 15.3355 | 2 | 51 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 31.1305 | 1 | 3 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 18.7522 | 3 | 11 |
| Thrombopoietin | Homo sapiens (human) | Potency | 17.3926 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 27.2411 | 3 | 30 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 21.9793 | 4 | 5 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 26.2382 | 5 | 12 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 3.3786 | 1 | 1 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 1.7291 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.8422 | 1 | 5 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.8422 | 1 | 5 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 31.7516 | 2 | 10 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 31.0736 | 2 | 19 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 9.4122 | 4 | 7 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 33.6084 | 1 | 12 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 16.9509 | 1 | 7 |
| Vpr | Human immunodeficiency virus 1 | Potency | 12.5893 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 11.5530 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 2.2555 | 2 | 2 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 2.2000 | 1 | 1 |
| 14-3-3 protein gamma | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 1 | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 0.3800 | 1 | 1 |
| 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | Cavia porcellus (domestic guinea pig) | IC50 | 1.7000 | 1 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 12,800.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 1.3120 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.8350 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 2.2360 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 1.1710 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 2.2360 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 1.1710 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | IC50 | 275.0000 | 1 | 2 |
| 5-lipoxygenase | Bos taurus (cattle) | IC50 | 0.7000 | 2 | 2 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 16.3116 | 2 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 28.0050 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 1,398.8000 | 3 | 3 |
| Acyl-CoA:cholesterol acyltransferase | Oryctolagus cuniculus (rabbit) | IC50 | 55.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 15.4240 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 6.1717 | 2 | 3 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 0.4610 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 0.4570 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 15.4240 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 8.7175 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 15.4240 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 8.7175 | 1 | 2 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 8.6575 | 4 | 4 |
| Alpha-synuclein | Homo sapiens (human) | Ki | 0.5000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 17.8305 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 19.0500 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | Ki | 12.5569 | 3 | 3 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 1.0667 | 2 | 6 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 2.9340 | 4 | 5 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | Ki | 3.8540 | 4 | 5 |
| Androgen receptor | Homo sapiens (human) | IC50 | 32.9333 | 3 | 3 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | IC50 | 0.5800 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 1.5240 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 107.5000 | 1 | 4 |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | IC50 | 0.6665 | 1 | 2 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 41.0000 | 1 | 1 |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | IC50 | 0.6665 | 1 | 2 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 8.1250 | 1 | 2 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 0.7242 | 5 | 5 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 84.6014 | 7 | 24 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 124.1800 | 2 | 5 |
| C-C chemokine receptor type 1 | Homo sapiens (human) | IC50 | 125.9465 | 1 | 2 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 32.6000 | 1 | 1 |
| C-C chemokine receptor type 5 | Homo sapiens (human) | IC50 | 81.7164 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Rattus norvegicus (Norway rat) | Ki | 7.9500 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 24.8570 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 19.6240 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 245.2000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 1.7177 | 1 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 0.6300 | 1 | 1 |
| Carnitine O-palmitoyltransferase 1, liver isoform | Homo sapiens (human) | IC50 | 10.0000 | 1 | 2 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 2 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Caspase-1 | Homo sapiens (human) | IC50 | 7.0200 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 4.6905 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Rattus norvegicus (Norway rat) | IC50 | 1.0500 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.2005 | 1 | 2 |
| CDGSH iron-sulfur domain-containing protein 2 | Homo sapiens (human) | IC50 | 3.5450 | 1 | 2 |
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | IC50 | 35.0600 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 10.4740 | 2 | 2 |
| core protein, partial | | IC50 | 35.9843 | 3 | 4 |
| COUP transcription factor 2 isoform a | Homo sapiens (human) | IC50 | 1.3150 | 1 | 1 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 10.4450 | 1 | 2 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | IC50 | 0.4200 | 1 | 1 |
| Cysteinyl leukotriene receptor 2 | Homo sapiens (human) | IC50 | 0.4200 | 1 | 1 |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 2 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 1.2200 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.0160 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 117.0000 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.2600 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 12.6667 | 2 | 3 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 8.1000 | 2 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Dehydrogenase/reductase SDR family member 9 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Deoxyhypusine hydroxylase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 2 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 212.5000 | 1 | 2 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 0.0360 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Francisella tularensis subsp. tularensis SCHU S4 | IC50 | 79.0000 | 1 | 1 |
| Estrogen receptor 1 | Homo sapiens (human) | IC50 | 22.1937 | 1 | 1 |
| Eukaryotic initiation factor 4A-I | Homo sapiens (human) | IC50 | 0.1390 | 4 | 4 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 1.1500 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | IC50 | 122.4000 | 1 | 1 |
| Forkhead box protein M1 | Homo sapiens (human) | Ki | 0.0520 | 1 | 1 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 29.0000 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | IC50 | 8.7000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 28.2000 | 1 | 1 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 10.4450 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 41.6241 | 1 | 2 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 0.7420 | 5 | 5 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 19.0000 | 1 | 1 |
| Glucose transporter | Leishmania mexicana | IC50 | 0.2420 | 1 | 1 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 46.6000 | 1 | 2 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 32.9600 | 3 | 6 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 16.3116 | 2 | 2 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.9009 | 1 | 1 |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.3100 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 1,581.7000 | 2 | 2 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 794.9000 | 4 | 4 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 1,581.8500 | 2 | 2 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 0.7300 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 0.0360 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 61.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.0940 | 3 | 3 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 4.5000 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 33.3520 | 3 | 3 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 0.9000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 3.2960 | 5 | 5 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 17.8850 | 1 | 2 |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | IC50 | 0.2525 | 2 | 2 |
| Linoleate 9S-lipoxygenase-4 | Glycine max (soybean) | IC50 | 22.0000 | 1 | 1 |
| Lipoxygenase | Glycine max (soybean) | IC50 | 23.3460 | 5 | 5 |
| Lipoxygenase | Solanum tuberosum (potato) | IC50 | 10.0000 | 1 | 1 |
| Lysine-specific demethylase 4A | Homo sapiens (human) | IC50 | 3.2750 | 2 | 2 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | Ki | 4.3300 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 5.5175 | 3 | 4 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| M17 leucyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 53.4500 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 0.5700 | 2 | 2 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 2.4300 | 1 | 1 |
| Methylcytosine dioxygenase TET2 | Homo sapiens (human) | IC50 | 46.0000 | 1 | 1 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 1.2380 | 1 | 1 |
| MPI protein | Homo sapiens (human) | IC50 | 0.2905 | 2 | 2 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0380 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 66.1250 | 1 | 4 |
| NAD-dependent protein deacetylase | Schistosoma mansoni | IC50 | 1.9000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 15.4000 | 1 | 1 |
| NADPH oxidase 1 | Homo sapiens (human) | IC50 | 0.3588 | 2 | 2 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil cytosol factor 1 | Homo sapiens (human) | Ki | 125.0000 | 3 | 3 |
| P2X purinoceptor 3 | Homo sapiens (human) | IC50 | 0.7550 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP14 | Homo sapiens (human) | Ki | 76.2000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | IC50 | 3.6000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | Ki | 3.4000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP3 | Homo sapiens (human) | Ki | 124.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP4 | Homo sapiens (human) | Ki | 24.2000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Ki | 200.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 | Homo sapiens (human) | Ki | 187.0000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 3.4100 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 1.1010 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | IC50 | 25.5266 | 18 | 19 |
| Peroxisome proliferator-activated receptor alpha | Mus musculus (house mouse) | IC50 | 0.6150 | 1 | 2 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Ki | 33.3000 | 1 | 1 |
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | IC50 | 32.0010 | 5 | 5 |
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Ki | 33.3000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | IC50 | 1.3583 | 52 | 61 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | IC50 | 0.7000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Rattus norvegicus (Norway rat) | IC50 | 0.7000 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Ki | 0.2588 | 25 | 30 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | IC50 | 0.1110 | 1 | 1 |
| phosphomannomutase 2 | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| Pleiotropic ABC efflux transporter of multiple drugs | Saccharomyces cerevisiae S288C | IC50 | 400.0000 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 200.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 5.2867 | 86 | 91 |
| Polyunsaturated fatty acid 5-lipoxygenase | Mus musculus (house mouse) | IC50 | 0.2073 | 3 | 3 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 1.4779 | 27 | 31 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 24.2000 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | IC50 | 20.5955 | 7 | 11 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Ki | 1.6000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 12.6921 | 10 | 14 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 2.6986 | 4 | 5 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | Ki | 2.7400 | 3 | 3 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | IC50 | 42.4722 | 4 | 9 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Rattus norvegicus (Norway rat) | IC50 | 0.2600 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 29.5000 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Progesterone receptor | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 20.1000 | 2 | 3 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 3.4420 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 150.0000 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 22.0333 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | IC50 | 26.2580 | 3 | 5 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 53.3974 | 6 | 7 |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | IC50 | 14.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | IC50 | 26.2580 | 3 | 5 |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | IC50 | 100,000.0000 | 1 | 1 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | IC50 | 100,000.0000 | 1 | 1 |
| Proto-oncogene c-Fos | Homo sapiens (human) | IC50 | 0.0079 | 1 | 1 |
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | IC50 | 18.5000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase S | Homo sapiens (human) | IC50 | 10.3000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 7.6675 | 2 | 4 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 0.6700 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 1.9314 | 19 | 30 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 1.8420 | 2 | 5 |
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | IC50 | 12.0617 | 1 | 2 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 13.1350 | 8 | 8 |
| Seed linoleate 9S-lipoxygenase | Glycine max (soybean) | IC50 | 400.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 6.3050 | 2 | 2 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 314.0000 | 1 | 1 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 130.0000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 40.0000 | 1 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 18.6360 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 14.8070 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 0.4610 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 0.4570 | 1 | 1 |
| Sodium/bile acid cotransporter | Homo sapiens (human) | IC50 | 5.1000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 0.2280 | 1 | 1 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 2,000.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 0.6166 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 0.3400 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 2.9512 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 2.2600 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 0.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Steryl-sulfatase | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Structural capsid protein | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 43.5000 | 2 | 2 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 156.0000 | 2 | 2 |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | IC50 | 97.6100 | 2 | 2 |
| Thromboxane-A synthase | Rattus norvegicus (Norway rat) | IC50 | 20.0000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 3.2630 | 1 | 2 |
| Toxin B | Clostridioides difficile | IC50 | 0.0172 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 5.2900 | 2 | 2 |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | IC50 | 0.8800 | 1 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 85.4210 | 1 | 1 |
| Transcription factor AP-1 | Homo sapiens (human) | IC50 | 0.0079 | 1 | 1 |
| Transmembrane prolyl 4-hydroxylase | Homo sapiens (human) | IC50 | 34.2000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 501.8500 | 1 | 2 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 501.8500 | 1 | 2 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 501.8500 | 1 | 2 |
| Tubulin alpha-1A chain | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Tubulin beta chain | Sus scrofa (pig) | IC50 | 10.0000 | 1 | 1 |
| Tumor necrosis factor ligand superfamily member 11 | Mus musculus (house mouse) | IC50 | 20.0000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 3.3000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 176.2500 | 2 | 4 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | Ki | 20.0000 | 1 | 1 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 5.7000 | 2 | 2 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 82.5780 | 5 | 5 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 82.5780 | 5 | 5 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| V-type proton ATPase subunit S1 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Vacuolar proton pump subunit B | Gallus gallus (chicken) | IC50 | 0.0300 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 37.4000 | 2 | 2 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 501.3950 | 2 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 1.6330 | 1 | 3 |
| C-C chemokine receptor type 1 | Homo sapiens (human) | EC50 | 32.8114 | 1 | 2 |
| C-C chemokine receptor type 5 | Homo sapiens (human) | EC50 | 19.4763 | 1 | 2 |
| C-C chemokine receptor type 8 | Homo sapiens (human) | EC50 | 40.9054 | 1 | 2 |
| calcineurin A1, putative | Candida dubliniensis CD36 | EC50 | 180.0000 | 1 | 1 |
| Cannabinoid receptor 2 | Mus musculus (house mouse) | EC50 | 0.0330 | 1 | 1 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | EC50 | 0.2200 | 1 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | EC50 | 0.0110 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | EC50 | 0.0110 | 1 | 1 |
| Cytochrome P450 3A5 | Homo sapiens (human) | EC50 | 0.0110 | 1 | 1 |
| Free fatty acid receptor 1 | Homo sapiens (human) | EC50 | 412.1562 | 1 | 2 |
| G-protein coupled receptor 35 | Homo sapiens (human) | EC50 | 16.5000 | 2 | 2 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | Kd | 4.1000 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 0.0210 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | EC50 | 0.0210 | 1 | 1 |
| heat shock protein 90 | Candida albicans | EC50 | 112.6818 | 3 | 4 |
| hexokinase HKDC1 | Homo sapiens (human) | EC50 | 38.8000 | 1 | 1 |
| hexokinase-1 isoform HKI | Homo sapiens (human) | EC50 | 41.9000 | 1 | 1 |
| Hsf1 protein | Mus musculus (house mouse) | EC50 | 2.3190 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | EC50 | 17.8000 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | EC50 | 0.4700 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | EC50 | 0.4700 | 1 | 1 |
| Methionine aminopeptidase 1 | Homo sapiens (human) | EC50 | 66.7733 | 3 | 3 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | EC50 | 1.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | EC50 | 0.4687 | 1 | 6 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | EC50 | 0.4687 | 1 | 6 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | EC50 | 0.4687 | 1 | 6 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | EC50 | 0.4687 | 1 | 6 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | EC50 | 0.4687 | 1 | 6 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 15.8833 | 3 | 6 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | EC50 | 6.7705 | 41 | 43 |
| Peroxisome proliferator-activated receptor alpha | Mus musculus (house mouse) | EC50 | 3.0000 | 1 | 1 |
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | EC50 | 6.1110 | 10 | 10 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | EC50 | 51.4692 | 185 | 202 |
| Peroxisome proliferator-activated receptor gamma | Mus musculus (house mouse) | EC50 | 0.4551 | 4 | 7 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Kd | 1.1677 | 8 | 8 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | EC50 | 0.4700 | 1 | 1 |
| POsterior Segregation | Caenorhabditis elegans | EC50 | 26.1110 | 1 | 1 |
| Procathepsin L | Homo sapiens (human) | EC50 | 1.6330 | 1 | 3 |
| regulator of G-protein signaling 16 | Homo sapiens (human) | EC50 | 1.8500 | 1 | 1 |
| regulator of G-protein signaling 19 | Homo sapiens (human) | EC50 | 4.0900 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | EC50 | 1.5700 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 1.6330 | 1 | 3 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 1.6330 | 1 | 3 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 1.6330 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 3.4956 | 3 | 7 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 2.5018 | 2 | 5 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Kd | 15.8200 | 3 | 5 |
| RGS7, partial | Homo sapiens (human) | EC50 | 1.2400 | 1 | 1 |
| RPL19A | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 0.7570 | 2 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | EC50 | 8.7550 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 1.6330 | 1 | 3 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 1.6330 | 1 | 3 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 1.5190 | 1 | 1 |
| Thrombin | Oryctolagus cuniculus (rabbit) | EC50 | 0.0110 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | EC50 | 25.1271 | 2 | 3 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 1.6330 | 1 | 3 |
| Transthyretin | Homo sapiens (human) | EC50 | 9.4667 | 3 | 3 |
| Zinc finger protein mex-5 | Caenorhabditis elegans | EC50 | 8.7550 | 1 | 1 |