Page last updated: 2024-09-28

Skin Syphilis

Cutaneous lesions arising from infection with Treponema pallidum. In the primary stage, 18-21 days following infection, one or more chancres appear. If untreated, the subsequent stages of the disease appear as syphilids. These eruptions are superficial, nondestructive, exanthematic, transient, macular roseolas that may later be maculopapular or papular polymorphous or scaly, pustular, pigmented eruptions.(Arnold, Odom, and James, Andrew's Diseases of the Skin, 8th ed, p409)

Synonyms(3)

Synonym
Skin Syphilis
Syphilis, Cutaneous
Syphilids

Research Excerpts

Overview

ExcerptReference
"The tertiary cutaneous syphilis is now extremely rare."( Drobacheff, C; Laurent, R; Merle, C; Moulin, T; Van Landuyt, H; Vigan, M, 1994)

Research

Studies (169)

TimeframeStudies, This Condition (%)All Conditions %
pre-199068 (40.24)23.3326
1990's24 (14.20)12.5806
2000's38 (22.49)18.1394
2010's38 (22.49)28.8240
2020's1 (0.59)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low10
salicylic acid0low90
niacinamide0low10
uracil0low20
urea0low10
ethoxzolamide0low10
gentamicin0low20
guaifenesin0low10
indomethacin0low10
2-propanol0low20
khellin0low20
methadone0low10
metronidazole0low20
minoxidil0low10
nevirapine0low10
pentamidine0low10
phenacetin0low10
potassium iodide0low10
probenecid0low20
procaine0low10
sulfanilamide0low10
thalidomide0low10
prednisolone0low20
prednisone0low30
penicillin g0low390
cyanides0low10
tyrosine0low10
cloxacillin0low10
desoxycorticosterone0low10
colchicine0low10
oxacillin0low10
ampicillin0low10
valine0low10
methylprednisolone0low10
benzathine0low20
thiazoles0low10
podophyllotoxin0low10
6-methyluracil0low20
erythromycin0low30
deoxycytidine0low10
streptomycin0low10
mercury0low20
zirconium0low10
bromine0low10
silver nitrate0low10
trolamine salicylate0low20
cephalexin0low10
amoxicillin0low30
amdinocillin0low10
permethrin0low10
cefmetazole0low10
fomesafen0low10
imiquimod0low10
lamivudine0low10
emtricitabine0low10
penicillin v benzathine0low10
benethamine penicillin0low10
cephalosporin c0low10
broadcillin0low10
organophosphonates0low10
cortisone0low10
trimethoprim, sulfamethoxazole drug combination0low10
inositol 3-phosphate0low70
clindamycin0low10
arsphenamine0low10
tenofovir0low10
bilirubin0low10
vitamin d 20low10
stigmasterol0low10
phenylephrine hydrochloride0low50
bismuth0low50
beryllium0low10
heroin0low10
poriferasterol monoglucoside0low10
hypericum0low10
chlorhexidine0low10
amoxicillin-potassium clavulanate combination0low10
apremilast0low10
emtricitabine, tenofovir disoproxil fumarate drug combination0low10
phosphatidylcholines0low30
ro13-99040low90
tetracycline0low20
chlortetracycline0low10
methacycline0low10
warfarin0low10
epidermal growth factor0low10
cyclosporine0low10
technetium tc 99m medronate0low10
chondroitin sulfates0low10
acyclovir0low10
rifampin0low10
valacyclovir0low10
sildenafil citrate0low10
concanavalin a0low20

Protein Targets (849)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit7007
RAR-related orphan receptor gamma220022
GLI family zinc finger 3240024
AR protein230023
aldehyde dehydrogenase 1 family, member A1180018
retinoic acid nuclear receptor alpha variant 1200020
retinoid X nuclear receptor alpha190019
estrogen nuclear receptor alpha330033
peroxisome proliferator-activated receptor delta110011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a140014
activating transcription factor 66006
v-jun sarcoma virus 17 oncogene homolog (avian)9009
Histone H2A.x7007
thyroid hormone receptor beta isoform a9009
heat shock protein beta-17007
nuclear factor erythroid 2-related factor 2 isoform 1200020
lamin isoform A-delta10200020
Voltage-dependent calcium channel gamma-2 subunit120012
Glutamate receptor 2120012
estrogen-related nuclear receptor alpha240024
Carbonic anhydrase 1012117
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain2002
Thymidine kinase 0101
thioredoxin reductase8008
phosphopantetheinyl transferase7007
GLS protein3003
TDP1 protein240024
Smad33003
thyroid stimulating hormone receptor9009
EWS/FLI fusion protein120012
arylsulfatase A2002
euchromatic histone-lysine N-methyltransferase 2180018
Bloom syndrome protein isoform 13003
hemoglobin subunit beta1001
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Solute carrier family 22 member 1 0203
ATP-binding cassette sub-family C member 3021021
Multidrug resistance-associated protein 4021021
Solute carrier family 22 member 60708
Bile salt export pump0808
Bile salt export pump032032
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 013013
Cytochrome P450 2J20505
Disintegrin and metalloproteinase domain-containing protein 173104
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60507
Thymidine kinase 0101
Solute carrier family 22 member 80509
Canalicular multispecific organic anion transporter 1022022
Thymidine kinase0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE130013
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
nuclear receptor subfamily 1, group I, member 3160016
cytochrome P450 family 3 subfamily A polypeptide 4120012
glucocorticoid receptor [Homo sapiens]240024
pregnane X nuclear receptor230023
nuclear factor erythroid 2-related factor 2 isoform 28008
importin subunit beta-1 isoform 14004
snurportin-14004
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 439009
Protein mono-ADP-ribosyltransferase PARP150202
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 58008
Ataxin-28008
Chain A, Beta-lactamase9009
Chain A, 2-oxoglutarate Oxygenase8008
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
apical membrane antigen 1, AMA14004
Beta-lactamase 0002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)7007
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
DNA polymerase kappa isoform 16006
Beta-lactamase SHV-10002
Beta-lactamase SHV-10002
Beta-lactamase0002
Kappa-type opioid receptor0103
Solute carrier family 15 member 1011012
Solute carrier family 15 member 10404
B2 metallo-beta-lactamase 0003
Solute carrier family 15 member 20707
Beta-lactamase 0002
Beta-lactamase 0002
Solute carrier family 15 member 20809
Beta-lactamase 0002
Beta-lactamase 0002
Chain A, Mutant Al2 6e7p9g0011
Chain A, Cruzipain6006
Beta-lactamase 0002
acid sphingomyelinase3003
farnesoid X nuclear receptor100010
Beta-lactamase 0002
Beta-lactamase 0002
Metallo-beta-lactamase type 20002
Metallo-beta-lactamase VIM-11 0002
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0002
Metallo-beta-lactamase0002
Beta-lactamase 0002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
chromobox protein homolog 1110011
thyroid hormone receptor beta isoform 2120012
DNA polymerase beta3003
geminin240024
Carbonic anhydrase 2011217
60 kDa heat shock protein, mitochondrial0505
Beta-lactamase OXA-70003
Spike glycoprotein5005
10 kDa heat shock protein, mitochondrial0505
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Thiosulfate sulfurtransferase0404
Metallo-beta-lactamase VIM-130002
Efflux transporter 0103
Beta-lactamase 0001
Beta-lactamase Toho-10002
Beta-lactamase 0103
Class D beta-lactamase0003
60 kDa chaperonin 0505
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0002
10 kDa chaperonin 0505
Metallo-b-lactamase 0003
Carbapenem-hydrolyzing beta-lactamase KPC0002
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0003
Beta-lactamase VIM-1 0002
ATP-dependent phosphofructokinase4004
Cytochrome P450 1A20506
Cytochrome P450 3A4010010
Cytochrome P450 2D60404
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Cytochrome P450 2C190505
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Carboxylic ester hydrolase 0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
Chain A, Putative fructose-1,6-bisphosphate aldolase5005
USP1 protein, partial100010
Microtubule-associated protein tau7007
vitamin D3 receptor isoform VDRA8008
caspase-1 isoform alpha precursor2002
Caspase-71001
Inositol monophosphatase 12002
Solute carrier organic anion transporter family member 1B30608
Solute carrier organic anion transporter family member 1B10608
Solute carrier family 22 member 80506
Insulin-degrading enzyme0101
bromodomain adjacent to zinc finger domain 2B4004
mitogen-activated protein kinase 17007
Interferon beta140014
Solute carrier family 22 member 80405
Chain A, JmjC domain-containing histone demethylation protein 3A3003
Chain A, BCL-2-RELATED PROTEIN A10022
Luciferase5005
interleukin 85005
acetylcholinesterase4004
PAX80003
glp-1 receptor, partial3003
15-lipoxygenase, partial3003
pregnane X receptor6006
SMAD family member 26006
SMAD family member 36006
caspase 7, apoptosis-related cysteine protease2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
PINK11001
estrogen receptor 2 (ER beta)5005
progesterone receptor120012
G8008
cytochrome P450 2D66006
67.9K protein4004
glucocerebrosidase3003
Parkin2002
peroxisome proliferator activated receptor gamma130013
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
heat shock protein 900011
caspase-32002
IDH16006
calcineurin A1, putative0011
aryl hydrocarbon receptor110011
thyroid stimulating hormone receptor4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
cytochrome P450 2D6 isoform 16006
hepatocyte nuclear factor 4-alpha isoform 20101
cellular tumor antigen p53 isoform a2002
cytochrome P450 2C19 precursor4004
cytochrome P450 2C9 precursor3003
perilipin-50101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d4004
transcriptional regulator ERG isoform 33003
huntingtin isoform 21001
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 11001
flap endonuclease 14004
protein AF-9 isoform a0001
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
nuclear receptor ROR-gamma isoform 15005
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
peripheral myelin protein 228008
cytochrome P450 3A4 isoform 17007
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10022
lethal factor (plasmid)5005
Gamma-aminobutyric acid receptor subunit pi7007
Synaptojanin-20101
Solute carrier family 22 member 20202
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Synaptojanin-10101
Solute carrier family 22 member 30303
Glutathione reductase, mitochondrial0102
HLA class I histocompatibility antigen, B alpha chain 8008
Cellular tumor antigen p53160016
Integrin beta-31001
72 kDa type IV collagenase0202
Integrin alpha-IIb1001
Matrix metalloproteinase-90101
Gamma-aminobutyric acid receptor subunit beta-17007
Gamma-aminobutyric acid receptor subunit delta7007
Gamma-aminobutyric acid receptor subunit gamma-27007
Gamma-aminobutyric acid receptor subunit alpha-57007
Gamma-aminobutyric acid receptor subunit alpha-37007
Gamma-aminobutyric acid receptor subunit gamma-17007
Gamma-aminobutyric acid receptor subunit alpha-27007
Gamma-aminobutyric acid receptor subunit alpha-47007
Gamma-aminobutyric acid receptor subunit gamma-37007
Trypanothione reductase0101
Gamma-aminobutyric acid receptor subunit alpha-67007
Alpha-synuclein1304
Histamine H2 receptor4004
Nuclear receptor ROR-gamma5005
Gamma-aminobutyric acid receptor subunit alpha-17007
Gamma-aminobutyric acid receptor subunit beta-37007
Gamma-aminobutyric acid receptor subunit beta-27007
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20202
Rap guanine nucleotide exchange factor 41001
GABA theta subunit7007
Inositol hexakisphosphate kinase 18008
Multidrug and toxin extrusion protein 10606
Gamma-aminobutyric acid receptor subunit epsilon7007
Spermine oxidase0101
cytochrome P450 2C9, partial8008
P2Y purinoceptor 120202
Protein-arginine deiminase type-40606
Beta-lactamase 0102
Beta-lactamase TEM0203
endonuclease IV2002
ATAD5 protein, partial3003
Fumarate hydratase1001
PPM1D protein5005
Thrombopoietin1001
polyprotein1001
nuclear receptor subfamily 1, group I, member 26006
nuclear receptor subfamily 0 group B member 10202
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A4004
steroidogenic factor 10202
muscleblind-like protein 1 isoform 13003
muscarinic acetylcholine receptor M13003
neuropeptide S receptor isoform A2002
Tubulin alpha-1A chain0426
Tubulin beta chain0426
Plasma kallikrein0002
Tubulin beta-4A chain0338
ATP-dependent translocase ABCB10404
Tubulin beta chain0338
ATP-dependent translocase ABCB10607
Tubulin alpha-3C chain0338
Serine/threonine-protein kinase pim-10101
ATP-dependent translocase ABCB10404
Tubulin alpha-1B chain0338
Tubulin alpha-4A chain0338
Tubulin beta-4B chain0338
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0338
Tubulin beta-2A chain0338
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0338
Tubulin beta-2B chain0303
Tubulin alpha-3E chain0338
Tubulin alpha-1A chain0338
Similar to alpha-tubulin isoform 1 0202
Similar to alpha-tubulin isoform 1 0202
CREB-binding protein1001
Tubulin alpha-1C chain0338
Tubulin beta-6 chain0338
Tubulin beta-2B chain0338
Tubulin beta-1 chain0338
dopamine D1 receptor1001
regulator of G-protein signaling 41001
peripheral myelin protein 22 isoform 12002
survival motor neuron protein isoform d7007
M-phase phosphoprotein 82002
Glucocorticoid receptor09216
Sex hormone-binding globulin0022
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0303
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
Carbonic anhydrase 40609
Carbonic anhydrase0405
Carbonic anhydrase 150405
Thymidine kinase 2 0101
Deoxycytidine kinase0001
Probable deoxycytidylate deaminase0001
Cytidine deaminase0001
AAA family ATPase 0001
Reverse transcriptase/RNaseH 03413
GALC protein3003
Solute carrier family 22 member 30101
Solute carrier family 22 member 20202
Albumin0268
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK11001
streptokinase A precursor0022
Motilin receptor0112
Rap guanine nucleotide exchange factor 35005
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
60 kDa chaperonin0202
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Potassium voltage-gated channel subfamily H member 20505
Cytochrome P450 1B10202
Lanosterol 14-alpha demethylase0415
50S ribosomal protein L36 20213
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0002
Carbonic anhydrase 0303
Nrf21001
Carbonic anhydrase 0202
Carbonic anhydrase 0202
Carbonic anhydrase0202
pyruvate kinase PKM isoform a1001
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Carbonic anhydrase0202
Carbonic anhydrase 120418
Prolyl endopeptidase0101
Glycogen phosphorylase, muscle form0101
Carbonic anhydrase 30306
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 2A0202
Translocator protein0101
Carbonic anhydrase 60418
Carbonic anhydrase 5A, mitochondrial0202
Dipeptidyl peptidase 40001
5-hydroxytryptamine receptor 2B0202
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0303
Carbonic anhydrase 5A, mitochondrial06010
Carbonic anhydrase 70317
Carbonic anhydrase0203
Mu-type opioid receptor0202
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 908011
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase 0203
Carbonic anhydrase 30101
Carbonic anhydrase0203
Carbonic anhydrase0203
Carbonic anhydrase 0202
Delta carbonic anhydrase0202
Carbonic anhydrase 0203
Carbonic anhydrase 130112
Carbonic anhydrase 40202
Carbonic anhydrase 130305
Carbonic anhydrase 140306
Carbonic anhydrase 5B, mitochondrial0408
unnamed protein product0101
heat shock protein HSP 90-alpha isoform 20102
Histone deacetylase 30101
Chymotrypsinogen A0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0101
Heme oxygenase 1 0101
Lanosterol 14-alpha demethylase0112
Aromatase0101
Cytochrome P450 11B1, mitochondrial0101
Cytochrome P450 11B2, mitochondrial0101
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0101
Histone deacetylase 40101
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10101
Sterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0112
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
14-alpha sterol demethylase 0011
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
heat shock protein 90, putative0001
likely tRNA 2'-phosphotransferase0101
Liver carboxylesterase 10001
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
Adenosine receptor A2a0202
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
Chain A, membrane-associated prostaglandin E synthase-20101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
serine/threonine-protein kinase mTOR isoform 11001
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0404
Cytochrome c oxidase subunit 20101
Epidermal growth factor receptor0101
Phospholipase A2, major isoenzyme0101
Prostaglandin G/H synthase 10405
Procathepsin L0101
Neuronal acetylcholine receptor subunit alpha-41102
Interleukin-80101
Androgen receptor0213
Neuronal acetylcholine receptor subunit beta-21102
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10202
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10101
Thromboxane-A synthase 0101
Adenosine receptor A10102
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10101
Caspase-10102
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0102
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20415
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Sodium- and chloride-dependent betaine transporter0101
C-X-C chemokine receptor type 30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G2002
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Prostaglandin G/H synthase 20303
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20203
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 70103
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0202
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
histone acetyltransferase KAT2A isoform 17007
Cytochrome P450 1A10202
Hsf1 protein0011
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Capsid protein 0123
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Multidrug transporter MdfA0202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0202
D(2) dopamine receptor0101
Cytochrome P450 2B60112
D(4) dopamine receptor0101
Mu-type opioid receptor0202
D(3) dopamine receptor0303
Delta-type opioid receptor0101
Kappa-type opioid receptor0101
Mas-related G-protein coupled receptor member X20011
Aldehyde oxidase 1 0101
nonstructural protein 11001
Nuclear receptor subfamily 1 group I member 20022
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Chain B, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain A, Hiv-1 Reverse Transcriptase0101
Chain B, Hiv-1 Reverse Transcriptase0101
Chain A, Reverse transcriptase/ribonuclease H0101
Prothrombin 0101
Renin0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0202
Imidazoleglycerol-phosphate dehydratase0101
Gag-Pol polyprotein0101
5-hydroxytryptamine receptor 1A0001
Ryanodine receptor 10101
Acetylcholinesterase0001
Cannabinoid receptor 10202
Microsomal triglyceride transfer protein large subunit0101
Exoribonuclease H 0101
Protease 0202
Cardiac ryanodine receptor 2 0101
Fructose-1,6-bisphosphatase 1 0001
Reverse transcriptase 0112
Chain A, NAD-dependent deacetylase0101
Caspase-71001
caspase-31001
Poly [ADP-ribose] polymerase 20101
NAD-dependent histone deacetylase SIR20101
Coagulation factor VII0101
Poly [ADP-ribose] polymerase 10101
Tissue factor0101
Cytochrome P450 3A50101
NAD-dependent protein deacetylase HST20101
Fatty-acid amide hydrolase 10101
NAD(+) hydrolase SARM10101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-60101
NAD-dependent protein deacetylase sirtuin-10101
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0101
NAD-dependent protein deacetylase 0101
MecA 0101
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Protein arginine N-methyltransferase 50101
5-hydroxytryptamine receptor 40202
Protein tyrosine phosphatase type IVA 30101
Coagulation factor X0101
Plasminogen0101
Urokinase-type plasminogen activator0101
Protein S100-B0112
Glyceraldehyde-3-phosphate dehydrogenase0101
Protein S100-B0011
Trypsin-10101
Aldo-keto reductase family 1 member B10202
Acrosin0101
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Angiotensin-converting enzyme0202
Amiloride-sensitive amine oxidase [copper-containing]0101
Amine oxidase [flavin-containing] A0101
Diamine acetyltransferase 10101
Sodium-dependent noradrenaline transporter 0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Sodium-dependent dopamine transporter 0202
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Protein tyrosine phosphatase type IVA 20101
Nuclear receptor subfamily 3 group C member 3 0202
Protein tyrosine phosphatase type IVA 10101
Aurora kinase B0101
Protein arginine N-methyltransferase 10101
Suppressor of tumorigenicity 14 protein0101
serine-protein kinase ATM isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Cytochrome P450 1A2 0002
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60202
UDP-glucuronosyltransferase 1A1 0202
UDP-glucuronosyltransferase 1A40101
Arylacetamide deacetylase0103
UDP-glucuronosyltransferase 2B10 0101
Arylacetamide deacetylase0001
Arylacetamide deacetylase0001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
alpha-galactosidase2002
NPC intracellular cholesterol transporter 1 precursor1001
Regulatory protein E20011
Regulatory protein E20011
Regulatory protein E20011
Calcium-activated potassium channel subunit alpha-10101
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
thioredoxin glutathione reductase3003
Solute carrier organic anion transporter family member 1A40202
UDP-glucuronosyltransferase 1A90101
Transient receptor potential cation channel subfamily A member 10011
Solute carrier organic anion transporter family member 1A10202
Solute carrier family 22 member 10101
Canalicular multispecific organic anion transporter 10101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Pannexin-10101
Solute carrier family 22 member 120101
Solute carrier organic anion transporter family member 1C10101
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Pannexin-10101
Solute carrier family 22 member 110203
Solute carrier family 22 member 70203
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
DNA-directed RNA polymerase subunit beta0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20103
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0202
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Carbonic anhydrase 0101
DNA polymerase beta0101
Carbonic anhydrase 20112
Cholinesterase0101
Carbonic anhydrase 0101
Protein argonaute-20011
Adenylate kinase isoenzyme 10001
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Adenylate kinase 2, mitochondrial0001
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
Alpha-1B adrenergic receptor0101
Neutrophil collagenase0101
Alpha-1D adrenergic receptor0101
Alpha-1A adrenergic receptor0101
Collagenase 30101
Integrase 0101
Cereblon isoform 40202
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0416
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Glutamate receptor ionotropic, NMDA 1 0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10202
SLC16A10 protein0001
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, NMDA 2D0001
Tubulin--tyrosine ligase0101
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Glutamate receptor ionotropic, NMDA 3A0001
Chain A, Uracil-DNA Glycosylase0101
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
Valacyclovir hydrolase0001
Chain A, Arginase 10101
eyes absent homolog 2 isoform a1001
Vitamin D3 receptor0001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]