Dubin-Johnson Syndrome

A benign, autosomally recessive inherited hyperbilirubinemia characterized by the presence of a dark pigment in the centrilobular region of the liver cells. There is a functional defect in biliary excretion of bilirubin, cholephilic dyes, and porphyrins. Affected persons may be asymptomatic or have vague constitutional or gastrointestinal symptoms. The liver may be slightly enlarged, and oral and intravenous cholangiography fails to visualize the biliary tract.

Synonym
Hyperbilirubinemia 2
Dubin-Johnson Syndrome
Hyperbilirubinemia II
Jaundice, Chronic Idiopathic

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	216 (77.98)	23.3326
1990's	21 (7.58)	12.5806
2000's	20 (7.22)	18.1394
2010's	12 (4.33)	28.8240
2020's	8 (2.89)	9.53

Drug	Relationship Strength	Studies
aminolevulinic acid	low	1
glycine	low	1
iodine	low	1
pyridoxal	low	1
uric acid	low	1
chlorpromazine	low	2
erythrosine	low	1
halothane	low	3
iodipamide	low	3
isoniazid	low	1
phenacetin	low	1
phenobarbital	low	15
salicylamide	low	1
sulfobromophthalein	low	71
prednisolone	low	1
estriol	low	5
thyroxine	low	1
penicillamine	low	1
prednisone	low	4
estrone	low	3
dehydroepiandrosterone	low	1
adrenochrome	low	1
aminopyrine	low	1
tyrosine	low	2
leucine	low	1
phenylalanine	low	1
norethindrone	low	1
mestranol	low	1
tryptophan	low	2
arginine	low	1
dehydrocholic acid	low	1
thymol	low	1
uridine diphosphate glucose	low	2
glycocholic acid	low	1
c.i. 42510	low	1
metanephrine	low	1
lanthanum	low	1
technetium	low	5
camptothecin	low	1
silver nitrate	low	1
urobilinogen	low	3
ursodeoxycholic acid	low	8
transferrin	low	1
irinotecan	low	1
vanadates	low	1
glutathione disulfide	low	1
coproporphyrin i	low	5
6-carboxyfluorescein	low	1
fibrinogen	low	1
glucuronic acid	low	1
s-(2,4-dinitrophenyl)glutathione	low	1
zinc coproporphyrin iii	low	3
methotrexate	low	1
deoxycholic acid	low	2
estradiol 3-benzoate	low	1
leupeptins	low	1
glycogen	low	1
griseofulvin	low	1
phalloidine	low	1
mycophenolic acid	low	1
benzyloxycarbonylleucyl-leucyl-leucine aldehyde	low	1
nadp	low	1
cytellin	low	2
bilirubin	medium	156
vitamin k semiquinone radical	low	2
leukotriene c4	low	2
bilirubin diglucuronide	low	1
leukotriene e4	low	1
vitamin k 1	low	1
arsenic	low	1
phosphorus	low	2
technetium tc 99m disofenin	low	4
indocyanine green	low	7
acid phosphatase	low	3
tin mesoporphyrin	low	1
heme	low	6
novobiocin	low	1
tetracycline	low	1
warfarin	low	2
technetium tc 99m lidofenin	low	3
nitrophenols	low	1
vitamin b 12	low	1
rifampin	low	3
cholestyramine resin	low	1

Protein Targets (891)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	8	0	0	8
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
thioredoxin reductase	11	0	0	11
GALC protein	3	0	0	3
GLI family zinc finger 3	18	0	0	18
nuclear receptor subfamily 1, group I, member 3	14	0	0	14
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
glucocorticoid receptor [Homo sapiens]	25	0	0	25
retinoic acid nuclear receptor alpha variant 1	21	0	0	21
retinoid X nuclear receptor alpha	16	0	0	16
estrogen-related nuclear receptor alpha	24	0	0	24
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	3	0	0	3
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
Bloom syndrome protein isoform 1	6	0	0	6
thyroid hormone receptor beta isoform a	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	20	0	0	20
geminin	24	0	0	24
peripheral myelin protein 22	10	0	0	10
survival motor neuron protein isoform d	8	0	0	8
muscleblind-like protein 1 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	6	1	0	7
ATP-binding cassette sub-family C member 3	0	10	0	10
Multidrug resistance-associated protein 4	0	11	0	12
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	2
Carbonic anhydrase 12	0	2	1	8
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	20	0	21
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	2	1	10
Carbonic anhydrase 2	0	2	2	10
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	3	1	5
Carbonic anhydrase 3	0	2	1	8
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	3	0	4
Steryl-sulfatase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	3	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2D6	0	2	1	3
Cytochrome P450 2A6	0	2	0	2
Cytochrome P450 2C9	0	6	1	7
5-hydroxytryptamine receptor 2A	0	3	0	3
Androgen receptor	0	11	0	11
Gamma-aminobutyric acid receptor subunit beta-1	6	1	0	7
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	6	1	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	6	1	0	7
Gamma-aminobutyric acid receptor subunit alpha-5	6	1	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	6	1	0	7
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	1	1	2
Carbonic anhydrase 4	0	2	1	7
Carbonic anhydrase 6	0	2	1	7
Gamma-aminobutyric acid receptor subunit gamma-1	6	1	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	6	1	0	7
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	1	0	3
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	6	1	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	6	1	0	7
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	6	1	0	7
Adenosine receptor A2a	0	1	0	3
5-hydroxytryptamine receptor 2B	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Cytochrome P450 2C19	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	1	3
Carbonic anhydrase 5A, mitochondrial	0	2	1	8
Carbonic anhydrase	0	1	0	4
Kappa-type opioid receptor	0	1	0	1
Carbonic anhydrase 7	0	2	1	7
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	2	1	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	4
D(2) dopamine receptor	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	6	1	0	7
Gamma-aminobutyric acid receptor subunit beta-3	6	1	0	7
Gamma-aminobutyric acid receptor subunit beta-2	6	1	0	7
Cholinesterase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	4	1	8
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Carbonic anhydrase 9	0	2	1	8
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	5
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	4
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	5
GABA theta subunit	6	1	0	7
Canalicular multispecific organic anion transporter 1	0	10	0	10
Carbonic anhydrase 4	0	2	0	2
Carbonic anhydrase 15	0	1	0	5
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	5
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	6	1	0	7
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	2	1	8
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	1	8
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	9	0	0	9
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
phosphopantetheinyl transferase	13	0	0	13
TDP1 protein	24	0	0	24
Microtubule-associated protein tau	10	0	0	10
vitamin D3 receptor isoform VDRA	11	0	0	11
DNA polymerase kappa isoform 1	8	0	0	8
histone acetyltransferase KAT2A isoform 1	11	0	0	11
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	1	0	1
Glutamate receptor 2	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Glutamate receptor 4	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Chain A, Ferritin light chain	4	0	0	4
Luciferase	8	0	0	8
interleukin 8	3	0	0	3
15-lipoxygenase, partial	4	0	0	4
RAR-related orphan receptor gamma	18	0	0	18
GLS protein	7	0	0	7
thyroid stimulating hormone receptor	9	0	0	9
estrogen receptor 2 (ER beta)	13	0	0	13
pregnane X nuclear receptor	14	0	0	14
estrogen nuclear receptor alpha	32	0	0	32
G	9	0	0	9
peroxisome proliferator-activated receptor delta	9	0	0	9
vitamin D (1,25- dihydroxyvitamin D3) receptor	13	0	0	13
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
activating transcription factor 6	7	0	0	7
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	10	0	0	10
chromobox protein homolog 1	14	0	0	14
thyroid hormone receptor beta isoform 2	20	0	0	20
histone deacetylase 9 isoform 3	3	0	0	3
lamin isoform A-delta10	16	0	0	16
Voltage-dependent calcium channel gamma-2 subunit	10	0	0	10
Interferon beta	14	0	0	14
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
Glutamate receptor 2	10	1	0	11
Nicotinate phosphoribosyltransferase	0	1	0	1
Inositol hexakisphosphate kinase 1	9	0	0	9
cytochrome P450 2C9, partial	9	0	0	9
ORF73	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	4	0	0	4
alpha-galactosidase	3	0	0	3
cytochrome P450 2C19 precursor	3	0	0	3
flap endonuclease 1	3	0	0	3
DNA polymerase iota isoform a (long)	9	0	0	9
muscarinic acetylcholine receptor M1	2	0	0	2
lethal factor (plasmid)	4	0	0	4
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	7	0	0	7
Proteasome subunit beta type-11	0	1	0	2
Fumarate hydratase	5	0	0	5
PPM1D protein	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
EWS/FLI fusion protein	8	0	0	8
polyprotein	5	0	0	5
Calpain-9	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	2
Cathepsin B	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Replicase polyprotein 1ab	0	2	1	3
Aromatase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Calpain-2 catalytic subunit	0	1	0	1
Proteasome subunit beta type-1	0	2	0	3
Proteasome subunit alpha type-1	0	1	0	2
Proteasome subunit alpha type-2	0	1	0	2
Proteasome subunit alpha type-3	0	1	0	2
Proteasome subunit alpha type-4	0	1	0	2
NF-kappa-B inhibitor alpha	0	0	1	1
Proteasome subunit beta type-8	0	1	0	2
Proteasome subunit beta type-9	0	1	0	2
Proteasome subunit alpha type-5	0	1	0	2
Proteasome subunit beta type-4	0	1	0	2
Proteasome subunit beta type-6	0	1	0	2
Proteasome subunit beta type-5	0	2	0	3
Proteasome subunit beta type-10	0	1	0	2
Cathepsin K	0	1	0	1
Proteasome subunit beta type-3	0	1	0	2
Proteasome subunit beta type-2	0	2	0	3
Proteasome subunit alpha type-6	0	1	1	3
Proteasome subunit alpha-type 8	0	1	0	2
Proteasome subunit beta type-7	0	1	0	2
Gamma-secretase subunit PEN-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
Chain A, 2-oxoglutarate Oxygenase	10	0	0	10
Chain A, Cruzipain	6	0	0	6
USP1 protein, partial	7	0	0	7
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	3	0	0	3
Solute carrier organic anion transporter family member 1B3	0	4	0	7
Solute carrier organic anion transporter family member 1B1	0	4	0	7
AR protein	23	0	0	23
progesterone receptor	15	0	0	15
peroxisome proliferator activated receptor gamma	15	0	0	15
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Cellular tumor antigen p53	18	0	0	18
ATPase family AAA domain-containing protein 5	6	0	0	6
Ataxin-2	7	0	0	7
DNA topoisomerase	0	1	0	1
ATAD5 protein, partial	7	0	0	7
Thrombopoietin	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
regulator of G-protein signaling 4	2	0	0	2
67.9K protein	7	0	0	7
glucocerebrosidase	1	0	0	1
putative alpha-glucosidase	1	0	0	1
lysosomal alpha-glucosidase preproprotein	2	0	0	2
peripheral myelin protein 22 isoform 1	3	0	0	3
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
huntingtin isoform 2	2	0	0	2
ras-related protein Rab-9A	2	0	0	2
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
nuclear receptor ROR-gamma isoform 1	5	0	0	5
cytochrome P450 3A4 isoform 1	6	0	0	6
M-phase phosphoprotein 8	4	0	0	4
relaxin receptor 1 isoform 1	2	0	0	2
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Histone deacetylase 3	0	1	0	1
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	0	0	1
DNA ligase	0	1	0	1
Integrin beta-3	3	0	0	3
Integrin alpha-IIb	3	0	0	3
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	1	1	7
DNA topoisomerase 2-alpha	0	2	0	2
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	8	0	8
Type-2 restriction enzyme HindIII	0	1	0	1
Histone deacetylase 4	0	1	0	1
Ribonuclease pancreatic	0	1	0	1
DNA topoisomerase 2-beta	0	0	0	1
DNA topoisomerase 1	0	1	0	2
Histone deacetylase 1	0	1	0	1
DNA topoisomerase 1	0	1	0	1
Integrase	0	3	0	3
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
acetylcholinesterase	4	0	0	4
Smad3	3	0	0	3
caspase 7, apoptosis-related cysteine protease	2	0	0	2
NADPH oxidase 1	0	1	0	1
farnesoid X nuclear receptor	9	0	0	9
cytochrome P450 2D6	5	0	0	5
Snq2p	0	0	0	1
caspase-3	2	0	0	2
IDH1	4	0	0	4
Adenylate cyclase type 1	0	2	0	2
thyroid stimulating hormone receptor	7	0	0	7
Histone H2A.x	8	0	0	8
Caspase-7	1	0	0	1
Spike glycoprotein	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
cytochrome P450 2D6 isoform 1	2	0	0	2
D(1A) dopamine receptor	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
caspase-3	1	0	0	1
heat shock protein beta-1	5	0	0	5
mitogen-activated protein kinase 1	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
Solute carrier family 22 member 1	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Transmembrane protease serine 2	0	1	1	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Bile salt export pump	0	6	0	6
5-hydroxytryptamine receptor 4	0	2	0	2
Potassium channel subfamily K member 2	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Albumin	0	1	4	5
Albumin	0	0	2	2
Major prion protein	0	0	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	0	2
Procathepsin L	0	1	1	2
Aldo-keto reductase family 1 member B1	0	6	0	6
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	4	0	4
ATP-dependent translocase ABCB1	0	1	0	2
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Replicase polyprotein 1a	0	1	1	2
Replicase polyprotein 1ab	0	1	1	2
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	2	0	3
Alpha-1B adrenergic receptor	0	5	0	5
Sphingomyelin phosphodiesterase	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	6	0	6
D	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	0	2
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	3
D(4) dopamine receptor	0	2	0	3
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	3	0	3
Sodium-dependent noradrenaline transporter	0	6	0	6
Sodium-dependent dopamine transporter	0	2	0	2
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
D(1B) dopamine receptor	0	2	0	2
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	0	2
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Histamine H1 receptor	0	1	1	2
Sodium-dependent serotonin transporter	0	12	0	12
Melanocortin receptor 4	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	3	1	7
D(3) dopamine receptor	0	2	0	3
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	1	0	1
Adenylate cyclase type 8	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	5	0	5
Histamine H2 receptor	3	0	0	3
5-hydroxytryptamine receptor 6	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Cytochrome P450 2J2	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	1	0	1
Spike glycoprotein	4	1	1	6
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	7
Glutamate receptor ionotropic, NMDA 2C	0	3	1	7
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	3	0	3
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	3	1	7
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Adenylyl cyclase 7	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	1	7
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Angiotensin-converting enzyme 2	0	1	1	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	1	7
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
DNA polymerase eta isoform 1	4	0	0	4
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
SMAD family member 2	5	0	0	5
SMAD family member 3	5	0	0	5
aryl hydrocarbon receptor	12	0	0	12
Sex hormone-binding globulin	0	0	5	5
Beta-glucuronidase	0	1	0	1
Corticosteroid-binding globulin	0	4	0	4
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Alpha-synuclein	3	5	0	8
TAR DNA-binding protein 43	6	0	0	6
G-protein coupled bile acid receptor 1	0	0	4	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
Steroid Delta-isomerase	0	0	1	1
Vitamin D3 receptor	0	2	2	4
Ileal sodium/bile acid cotransporter	0	2	0	2
Bile acid receptor	0	1	2	3
Genome polyprotein	0	2	2	4
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
thioredoxin glutathione reductase	4	0	0	4
hypothetical protein, conserved	1	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
eyes absent homolog 2 isoform a	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
glp-1 receptor, partial	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
streptokinase A precursor	0	0	1	1
Estrogen receptor	0	12	1	14
Glucocorticoid receptor	0	10	3	18
Estrogen receptor	0	0	2	2
Glycine receptor subunit alpha-1	0	10	0	10
Adenosine receptor A3	0	2	0	2
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Estrogen receptor beta	0	0	2	2
UDP-glucuronosyltransferase 2B7	0	1	0	2
Solute carrier organic anion transporter family member 1A1	0	3	0	4
Lanosterol 14-alpha demethylase	0	0	1	1
Olfactory receptor 51E2	0	0	2	2
UDP-glucuronosyltransferase 1A10	0	0	0	2
endonuclease IV	1	0	0	1
nonstructural protein 1	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
glucokinase regulatory protein	1	0	0	1
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
Rap guanine nucleotide exchange factor 3	4	0	0	4
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Cytochrome P450 1B1	0	1	0	1
Estrogen receptor beta	0	3	1	5
Ghrelin O-acyltransferase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
Glutathione reductase	0	0	0	1
Multidrug resistance-associated protein 1	0	0	0	2
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	5	0	6
Proton-coupled amino acid transporter 1	0	2	0	3
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Sodium/bile acid cotransporter	0	0	0	1
Multidrug resistance associated protein	0	1	0	3
Bile salt export pump	0	0	0	1
pregnane X receptor	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Heme oxygenase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Nuclear receptor ROR-gamma	3	0	0	3
Lanosterol 14-alpha demethylase	0	2	0	2
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	2
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	2	0	2
Liver carboxylesterase 1	0	0	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Multidrug and toxin extrusion protein 1	0	3	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Polyphenol oxidase 2	0	3	0	4
Myeloperoxidase	0	2	0	2
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	3	0	4
DNA gyrase subunit B	0	3	1	4
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	3	0	3
DNA gyrase subunit A	0	3	0	3
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	3
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	3	0	3
Phospholipase A-2-activating protein	0	3	0	3
Cysteinyl leukotriene receptor 2	0	0	2	2
Cysteinyl leukotriene receptor 1	0	0	2	2
Canalicular multispecific organic anion transporter 1	0	2	0	3
P2Y purinoceptor 12	0	1	1	2
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Cannabinoid receptor 1	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
dopamine D1 receptor	1	0	0	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
transcriptional regulator ERG isoform 3	2	0	0	2
importin subunit beta-1 isoform 1	1	0	0	1
DNA polymerase beta	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
snurportin-1	1	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	3
Solute carrier family 22 member 6	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	2
Protein-arginine deiminase type-4	0	2	0	2
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Glutamate receptor 1	0	1	0	1
Glutamate receptor 3	0	1	0	1
Glutamate receptor 4	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	3
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A7	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Amyloid-beta precursor protein	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Progesterone receptor	0	4	2	7
Chain A, Gyrase	0	0	1	1
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90-alpha	0	0	2	2
Heat shock protein HSP 90-beta	0	1	2	4
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit B	0	1	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
Cell division inhibitor SulA	0	0	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Heat shock protein HSP 90	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA topoisomerase	0	1	0	1
Microtubule-associated proteins 1A/1B light chain 3B	0	2	1	3
Microtubule-associated proteins 1A/1B light chain 3A	0	2	1	3
Solute carrier family 2, facilitated glucose transporter member 9	0	2	2	4
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Cytochrome P450 1A2	0	0	0	2
UDP-glucuronosyltransferase 1-6	0	1	0	1
Arylacetamide deacetylase	0	1	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Plasma kallikrein	0	0	0	3
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	3
Carbonic anhydrase-like protein, putative	0	0	0	3
Large neutral amino acids transporter small subunit 1	0	1	0	1
Monocarboxylate transporter 10	0	0	0	3
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	3	0	3
Glutamine synthetase	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Nociceptin receptor	0	0	1	1
Pyridoxal kinase	0	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Stromelysin-1	0	2	1	3
cytochrome P450 2C9 precursor	1	0	0	1
Endothelin-1 receptor	0	2	0	2
Endothelin-1 receptor	0	1	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain B, Odorant-binding Protein	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Acetylcholinesterase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Secreted chorismate mutase	0	1	0	1
Heat sensitive channel TRPV3	0	0	1	1
Transient receptor potential cation channel subfamily A member 1	0	1	1	2
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
apical membrane antigen 1, AMA1	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Substance-P receptor	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Guanine deaminase	0	1	0	1
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 14	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Sodium/bile acid cotransporter	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
M1-family alanyl aminopeptidase	0	1	0	1
Receptor-type tyrosine-protein phosphatase F	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research

Studies (277)

Protein Targets (891)

Dubin-Johnson Syndrome

Synonyms(4)

Research

Studies (277)

Drugs Studied (102)

Protein Targets (891)