C21-steroid hormone

A steroid compound with a structure based on a 21-carbon (pregnane) skeleton that acts as a hormone.

ChEBI ID: 64600

Members (3)

Member	Definition	Role
5-alpha-dihydroprogesterone	A C21-steroid hormone that is 5alpha-pregnane substituted by oxo groups at positions 3 and 20. It is a metabolite of progestrone.	5alpha-pregnane-3,20-dione
aldosterone	A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.	aldosterone
triamcinolone	A C21-steroid hormone that is 1,4-pregnadiene-3,20-dione carrying four hydroxy substituents at positions 11beta, 16alpha, 17alpha and 21 as well as a fluoro substituent at position 9. Used in the form of its 16,17-acetonide to treat various skin infections.	triamcinolone