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piperidinemonocarboxylic acid

Any member of the class of piperidines in which one of the carbons of the piperidine ring is substituted by a carboxy group.

ChEBI ID: 26148

Members (9)

MemberDefinitionRole
2,2,6,6-tetramethylpiperidine-n-oxide-4-amino-4-carboxylic acidTOAC
5-hydroxypipecolic acidA piperidinemonocarboxylic acid that is pipecolic acid with a hydroxy substituent at position 5.5-hydroxypipecolic acid
delta(1)-piperidine-2-carboxylic acid1-piperideine-2-carboxylic acid zwitterion; 1-piperideine-2-carboxylic acid
difenoxinA piperidinemonocarboxylic acid that is 4-phenylpiperidine-4-carboxylic acid in which the hydrogen attached to the nitrogen atom is substituted by a 3-cyano-3,3-diphenylpropyl group.difenoxin
N-hydroxypipecolic acidAn N-hydroxy-alpha-amino-acid resulting from the formal N-hydroxylation of the amino group of piperidine-carboxylic acid (pipecolic acid).N-hydroxypipecolic acid
nipecotic acidA piperidinemonocarboxylic acid that is piperidine in which one of the hydrogens at position 3 is substituted by a carboxylic acid group.nipecotic acid
pipecolic acidA piperidinemonocarboxylic acid in which the carboxy group is located at position C-2.pipecolic acid
tempo carboxylic acidA member of the class of aminoxyls that is TEMPO carrying a carboxy group at position 4.4-carboxy-TEMPO
tiagabineA piperidinemonocarboxylic acid that is (R)-nipecotic acid in which the hydrogen attached to the nitrogen has been replaced by a 1,1-bis(3-methyl-2-thienyl)but-1-en-4-yl group. A GABA reuptake inhibitor, it is used (generally as the hydrochloride salt) for the treatment of epilepsy.tiagabine

Research

Studies (1,229)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990167 (13.59)18.7374
1990's308 (25.06)18.2507
2000's422 (34.34)29.6817
2010's258 (20.99)24.3611
2020's74 (6.02)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials106 (7.17%)5.53%
Reviews131 (8.86%)6.00%
Case Studies88 (5.95%)4.05%
Observational1 (0.07%)0.25%
Other1,153 (77.96%)84.16%